Rat Pol beta

From Rattus norvegicus (aliases:beta-pol, rPol beta)
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Welcome to the Polymerase Page

This page presents all the information in Polbase for Rat Pol beta.

Mutants:

At the top of the page you'll find a map of all positions of known mutants. Text links to mutants and digestion products are listed in the Mutants section.

Structures/Sequence:

If available, a representative structure is displayed at the upper right. All known structures are listed in the Structures section.

External links:

Polbase polymerases are linked to UniProt and Genbank where possible. The UniProt search link directs you to a pre-constructed UniProt search containing relevant terms.

References:

All references that refer to this Polymerase are listed with their topics and paper's title in the References table.

Results:

All the results for this polymerase can be examined by following the "Results" link at the bottom of the page.

Help icons:

The show help symbol in the upper-right corner of the page links to this help text. The question mark icon is used everywhere to indicate that help is available.

Missing mutants?
Rat Pol beta is a family X enzyme from Rattus norvegicus.

Selected Properties for Rat Pol beta:

 3'-5' exo activity 5'-3' exo activity Frameshift Rate Substitution Rate General Error Rate
Yes (1) no data 3.6e-02 errors/bp (1) 2.2e-02 errors/bp (1) 6.4e-02 errors/bp (1)
Year Authors Title Results by property
2013 Yoshiyuki Mizushina, Isoko Kuriyama, Tatsuo Nakahara, Yoshihito Kawashima, Hiromi Yoshida Inhibitory effects of α-mangostin on ...
2013 Chelsea L Gridley, Sneha Rangarajan, Susan J Firbank, Shibani Dalal, Joann B Sweasy, Joachim Jaeger Structural changes in the hydrophobic...
2012 V N Vyjayanti, Umakanta Swain, Kalluri Subba Rao Age-related decline in DNA polymerase...
2011 Joann B Sweasy, Joachim Jaeger, Drew L Murphy A Triad Interaction in the Fingers Su...
2010 Ken Hirano, Yuichiro Yoshida, Tomomi Ishido, Yukihisa Wada, Naoji Moriya, Naoshi Yamazaki, Yoshiyuki Mizushina, Yoshinobu Baba, Mitsuru Ishikawa Consecutive incorporation of fluoroph...
2010 Matthew J Cuneo, Robert E London Oxidation state of the XRCC1 N-termin...
2008 Kuo-Hsiang Tang, Marc Niebuhr, Chang-Shung Tung, Hsiu-Chien Chan, Chia-Cheng Chou, Ming-Daw Tsai Mismatched dNTP incorporation by DNA ...
2007 Melanie F Brown, Jeffrey A Stuart Correlation of mitochondrial superoxi...
2007 George C Lin, Joachim Jaeger, Joann B Sweasy Loop II of DNA polymerase beta is imp...
2007 Tieming Lang, Shibani Dalal, Anna K Chikova, Daniel Dimaio, Joann B Sweasy The E295K DNA polymerase beta gastric...
2002 Yoshiyuki Mizushina, Shinji Kamisuki, Nobuyuki Kasai, Tomomi Ishidoh, Noriko Shimazaki, Masaharu Takemura, Hitomi Asahara, Stuart Linn, Shonen Yoshida, Osamu Koiwai, Fumio Sugawara, Hiromi Yoshida, Kengo Sakaguchi Petasiphenol: a DNA polymerase lambda...
2001 J W Arndt, W Gong, Xuejun Zhong, Alexander K Showalter, Jianhua Liu, Christopher A Dunlap, Z Lin, C Paxson, Ming-Daw Tsai, M K Chan Insight into the catalytic mechanism ...
2000 Mark W Maciejewski, D Liu, Rajendra Prasad, Samuel H Wilson, Gregory P Mullen Backbone dynamics and refined solutio...
2000 Igor V Shevelev, N V Belyakova, T P Kravetskaya, V M Krutyakov Autonomous 3'-->5' exonucleases can p... 3-5' exo,All properties
1999 Y Timsit DNA structure and polymerase fidelity.
1997 J Ahn, B G Werneburg, Ming-Daw Tsai DNA polymerase beta: structure-fideli...
1997 V S Kraynov, B G Werneburg, Xuejun Zhong, H Lee, J Ahn, Ming-Daw Tsai DNA polymerase beta: analysis of the ...
1996 D Liu, Rajendra Prasad, Samuel H Wilson, Eugene F DeRose, Gregory P Mullen Three-dimensional solution structure ...
1996 H Pelletier, M R Sawaya Characterization of the metal ion bin...
1994 M R Sawaya, H Pelletier, A Kumar, Samuel H Wilson, J Kraut Crystal structure of rat DNA polymera...
1987 Akio Matsukage, K Nishikawa, T Ooi, Y Seto, Masamitsu Yamaguchi Homology between mammalian DNA polyme...
1985 Thomas A Kunkel The mutational specificity of DNA pol... Cloned or native,Full length or truncated,Frameshift Error Rate,Nucleotide Substitution Rate,Overall Error Rate,All properties
1973 A M de Recondo, J A Lepesant, O Fichot, L Grasset, J M Rossignol, M Cazillis Synthetic template specificity of a d...
1971 H Berger, R C Huang, J L Irvin Purification and characterization of ...
Protein sequence:
Name 3'-5' exo activity 5'-3' exo activity Frameshift Rate Substitution Rate General Error Rate
Rat Pol beta I260Q

Version:20241007

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