HIV RT L74V

From HIV
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This page presents all the information in Polbase for HIV RT L74V.

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Mutant of: HIV RT (L74V)

HIV RT L74V is a family RT enzyme from HIV. "From the Los Alamos National Labs HIV Mutant database (now offline):|id:353|codon:TTA>GTA|drugs:1592U89 "From the Los Alamos National Labs HIV Mutant database (now offline):|id:354|codon:TTA>GTA|drugs:ddC "From the Los Alamos National Labs HIV Mutant database (now offline):|id:355|codon:TTA>GTA|drugs:ddI From the Los Alamos National Labs HIV Mutant database (now offline):|id:356|codon:TTA>GTA|drugs:DXG|class:Nucleoside RT Inhibitor (NRTI)|notes:4-fold resistance From the Los Alamos National Labs HIV Mutant database (now offline):|id:357|codon:TTA>GTA|drugs:HBY 097|class:HIV-1 Specific RT Inhibitor (NNRTI)|notes:4-fold resistance

Selected Properties for HIV RT L74V:

 3'-5' exo activity 5'-3' exo activity Frameshift Rate Substitution Rate General Error Rate
no data no data no data no data no data
Year Authors Title Results by property
2000 Holly Z Bazmi, J L Hammond, S C Cavalcanti, Chung K Chu, Raymond F Schinazi, John W Mellors In vitro selection of mutations in th...
1997 M Tisdale, T Alnadaf, D Cousens Combination of mutations in human imm...
1996 Jörg-Peter Kleim, M Rösner, I Winkler, A Paessens, R Kirsch, Y Hsiou, Edward Arnold, G Riess Selective pressure of a quinoxaline n...
1991 M H St Clair, J L Martin, G Tudor-Williams, M C Bach, C L Vavro, D M King, P Kellam, S D Kemp, Brendan A Larder Resistance to ddI and sensitivity to ...
1991 M H St Clair, J L Martin, G Tudor-Williams, M C Bach, C L Vavro, D M King, P Kellam, S D Kemp, Brendan A Larder Resistance to ddI and sensitivity to ...

Version:20241007

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