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Welcome to the Polymerase Page

This page presents all the information in Polbase for HIV RT K103R.


At the top of the page you'll find a map of all positions of known mutants. Text links to mutants and digestion products are listed in the Mutants section.


If available, a representative structure is displayed at the upper right. All known structures are listed in the Structures section.

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Mutant of: HIV RT (K103R)

HIV RT K103R is a family RT enzyme from HIV. "From the Los Alamos National Labs HIV Mutant database (now offline):|id:412|codon:AAA>AGA|drugs:LY-300046 HCl From the Los Alamos National Labs HIV Mutant database (now offline):|id:414|codon:AAA>AGA|drugs:O-(2-Phenoxy ethyl)benzoyl (phenyl) thiocarbamate 17c|class:HIV-1 Specific RT Inhibitor (NNRTI)|notes:Low potency also against K103N/Y181C

Selected Properties for HIV RT K103R:

3'-5' exo activity 5'-3' exo activity Frameshift Rate Substitution Rate General Error Rate
no data no data no data no data no data
Year Authors Title Results by property
2003 Angelo Ranise, Andrea Spallarossa, Silvia Schenone, Olga Bruno, Francesco Bondavalli, Laura Vargiu, Tiziana Marceddu, Massimo Mura, Paolo La Colla, Alessandra Pani Design, synthesis, SAR, and molecular...
1995 Haijiang Zhang, L Vrang, K Bäckbro, P Lind, Christer Sahlberg, Torsten Unge, Bo Oberg Inhibition of human immunodeficiency ...

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