HIV RT V179D

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Mutant of: HIV RT (V179D)

HIV RT V179D is a family RT enzyme from HIV. "From the Los Alamos National Labs HIV Mutant database (now offline):|id:467|codon:GTT>GAT|drugs:8-chloro-TIBO From the Los Alamos National Labs HIV Mutant database (now offline):|id:468|codon:GTT>GAT|drugs:ADAMII|class:HIV-1 Specific RT Inhibitor (NNRTI)|notes:28-fold. Tested against a site-directed mutant. "From the Los Alamos National Labs HIV Mutant database (now offline):|id:469|codon:GTT>GAT|drugs:DMP-266 "From the Los Alamos National Labs HIV Mutant database (now offline):|id:470|codon:GTT>GAT|drugs:L-697 "From the Los Alamos National Labs HIV Mutant database (now offline):|id:471|codon:GTT>GAT|drugs:LY-300046 HCl From the Los Alamos National Labs HIV Mutant database (now offline):|id:472|codon:GTT>GAT|drugs:QM96521|class:HIV-1 Specific RT Inhibitor (NNRTI)|notes:10-fold resistant. Other TTD-derivatives are 15-140 fold-R. From the Los Alamos National Labs HIV Mutant database (now offline):|id:473|codon:GTT>GAT|drugs:TIBO R82913|class:HIV-1 Specific RT Inhibitor (NNRTI)|notes:20-fold "From the Los Alamos National Labs HIV Mutant database (now offline):|id:474|codon:GTT>GAT|drugs:UC-10

Selected Properties for HIV RT V179D:

 3'-5' exo activity 5'-3' exo activity Frameshift Rate Substitution Rate General Error Rate
no data no data no data no data no data
Year Authors Title Results by property
1998 Mark Cushman, A Casimiro-Garcia, E Hejchman, J A Ruell, M Huang, C A Schaeffer, K Williamson, W G Rice, Robert W Buckheit New alkenyldiarylmethanes with enhanc...
1998 Myriam Witvrouw, M E Arranz, Christophe Pannecouque, R Declercq, H Jonckheere, J C Schmit, A-M Vandamme, J A Diaz, S T Ingate, J Desmyter, Robert Esnouf, L Van Meervelt, S Vega, Jan Balzarini, Erik De Clercq 1,1,3-Trioxo-2H,4H-thieno[3,4-e][1,2,...
1996 Jan Balzarini, H Pelemans, Stefano Aquaro, CF Perno, Myriam Witvrouw, Dominique Schols, Erik De Clercq, Anna Karlsson Highly favorable antiviral activity a...
1996 D L Winslow, S Garber, C Reid, H Scarnati, D Baker, M M Rayner, E D Anton Selection conditions affect the evolu...
1995 Haijiang Zhang, L Vrang, K Bäckbro, P Lind, Christer Sahlberg, Torsten Unge, Bo Oberg Inhibition of human immunodeficiency ...
1994 A-M Vandamme, Zeger Debyser, Rudi Pauwels, K De Vreese, P Goubau, M Youle, B Gazzard, P A Stoffels, G F Cauwenbergh, J Anne Characterization of HIV-1 strains iso...
1993 V W Byrnes, V V Sardana, W A Schleif, J H Condra, J A Waterbury, J A Wolfgang, W J Long, C L Schneider, A J Schlabach, B S Wolanski Comprehensive mutant enzyme and viral...

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