Selection conditions affect the evolution of specific mutations in the reverse transcriptase gene associated with resistance to DMP 266.

Winslow DL, Garber S, Reid C, Scarnati H, Baker D, Rayner MM, Anton ED
AIDS (London, England) (1996), Volume 10, Page 1205
PubMed entry

Abstract:

To monitor the appearance of HIV-1 variants resistant to inhibition by ...
To monitor the appearance of HIV-1 variants resistant to inhibition by DMP 266, a benzoxazinone non-nucleoside reverse transcriptase inhibitor using two different protocols for applying drug selective pressure in tissue culture. To compare the phenotype and genotype of viral isolates selected by each method.

Polymerases:

HIV RT L100I,HIV RT V108I,HIV RT V179D,HIV RT Y181C,HIV RT

Topics:

Status:

new topics/pols set partial results complete validated

Results:

No results available for this paper.
Log in to add missing results...

Entry validated by:

Log in to validate this paper...

Version:20240423

Using Polbase tables:

Sorting:

Tables may be sorted by clicking on any of the column titles. A second click reverses the sort order. <Ctrl> + click on the column titles to sort by more than one column (e.g. family then name).

Filtering:

It is also possible to filter the table by typing into the search box above the table. This will instantly hide lines from the table that do not contain your search text.