MMuLV RT

From Moloney Murine Leukemia Virus (aliases:MLV, Moloney Murine Leukemia Virus Reverse Transcriptase, M-MuLV RT)
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Welcome to the Polymerase Page

This page presents all the information in Polbase for MMuLV RT.

Mutants:

At the top of the page you'll find a map of all positions of known mutants. Text links to mutants and digestion products are listed in the Mutants section.

Structures/Sequence:

If available, a representative structure is displayed at the upper right. All known structures are listed in the Structures section.

External links:

Polbase polymerases are linked to UniProt and Genbank where possible. The UniProt search link directs you to a pre-constructed UniProt search containing relevant terms.

References:

All references that refer to this Polymerase are listed with their topics and paper's title in the References table.

Results:

All the results for this polymerase can be examined by following the "Results" link at the bottom of the page.

Help icons:

The show help symbol in the upper-right corner of the page links to this help text. The question mark icon is used everywhere to indicate that help is available.

Missing mutants?
MMuLV RT is a family RT enzyme from Moloney Murine Leukemia Virus.

Selected Properties for MMuLV RT:

 3'-5' exo activity 5'-3' exo activity Frameshift Rate Substitution Rate General Error Rate
No (1) no data no data no data no data
Year Authors Title Results by property
2009 LaTeca S Glass, Binh Nguyen, Kristie D Goodwin, Christophe Dardonville, W David Wilson, Eric C Long, Millie M Georgiadis Crystal structure of a trypanocidal 4...
2008 Kristie D Goodwin, Mark A Lewis, Eric C Long, Millie M Georgiadis Crystal structure of DNA-bound Co(III...
2006 Kristie D Goodwin, Mark A Lewis, Farial A Tanious, Richard R Tidwell, W David Wilson, Millie M Georgiadis, Eric C Long A high-throughput, high-resolution st...
2006 Sherwin P Montaño, Marie L Coté, Monica J Roth, Millie M Georgiadis Crystal structures of oligonucleotide...
2005 Darwin J Operario, Holly M Reynolds, Baek Kim Comparison of DNA polymerase activiti... Molecular Weight,All properties
2005 Kristie D Goodwin, Eric C Long, Millie M Georgiadis A host-guest approach for determining...
2004 Debanu Das, Millie M Georgiadis The crystal structure of the monomeri... RT,All properties
2000 S Najmudin, Marie L Coté, D Sun, S Yohannan, Sherwin P Montano, J Gu, Millie M Georgiadis Crystal structures of an N-terminal f...
1994 S H Whiting, J J Champoux Strand displacement synthesis capabil... Nick Extension,Strand Displacement,All properties
1992 J J DeStefano, R G Buiser, L M Mallaber, P J Fay, Robert A Bambara Parameters that influence processive ... RT,Cloned or native,Full length or truncated,Specific Activity,RNase H,All properties
1989 J D Roberts, Bradley D Preston, L A Johnston, A Soni, Lawrence A Loeb, Thomas A Kunkel Fidelity of two retroviral reverse tr... RT,3-5' exo,Molecular Weight,RNase H,All properties
1985 M J Roth, N Tanese, S P Goff Purification and characterization of ...
1975 I M Verma Studies on reverse transcriptase of R... Molecular Weight,RNase H,All properties
Protein sequence:
Name 3'-5' exo activity 5'-3' exo activity Frameshift Rate Substitution Rate General Error Rate
MMuLV RT N term R116A
MMuLV RT N term

Version:20240415

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