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Welcome to the Polymerase Page

This page presents all the information in Polbase for HBV RT.


At the top of the page you'll find a map of all positions of known mutants. Text links to mutants and digestion products are listed in the Mutants section.


If available, a representative structure is displayed at the upper right. All known structures are listed in the Structures section.

External links:

Polbase polymerases are linked to UniProt and Genbank where possible. The UniProt search link directs you to a pre-constructed UniProt search containing relevant terms.


All references that refer to this Polymerase are listed with their topics and paper's title in the References table.


All the results for this polymerase can be examined by following the "Results" link at the bottom of the page.

Help icons:

The show help symbol in the upper-right corner of the page links to this help text. The question mark icon is used everywhere to indicate that help is available.

HBV RT is a family RT enzyme from Hepatitis B.

Selected Properties for HBV RT:

3'-5' exo activity 5'-3' exo activity Frameshift Rate Substitution Rate General Error Rate
no data no data no data no data no data
Year Authors Title Results by property
2013 John E Tavis, Xiaohong Cheng, Yuan Hu, Michael Totten, Feng Cao, Eleftherios Michailidis, Rajeev Aurora, Marvin J Meyers, E Jon Jacobsen, Michael A. Parniak, Stefan G Sarafianos The hepatitis B virus ribonuclease h ...
2012 Eleftherios Michailidis, Karen A Kirby, Atsuko Hachiya, Wangdon Yoo, Sun Pyo Hong, Soo-Ok Kim, William R Folk, Stefan G Sarafianos Antiviral therapies: Focus on hepatit...
2012 Xiu-Juan Jiao, Xun Peng, Xiu-Min Jiao, Jin-Sheng Wang, Xie-Wen Sun, Pei-Li Zhao, Shou-Yun Wang, Jia-Qun Liu, Tong Li, Jing-Xian Yang [Mutation analysis of the HBV reverse...
2011 Eleftherios Michailidis, Kamlendra Singh, Karen A Kirby, Atsuko Hachiya, Wangdon Yoo, Sun Pyo Hong, Soo-Ok Kim, William R Folk, Stefan G Sarafianos Hepatitis B Virus genotypic differenc...

Using Polbase tables:


Tables may be sorted by clicking on any of the column titles. A second click reverses the sort order. <Ctrl> + click on the column titles to sort by more than one column (e.g. family then name).


It is also possible to filter the table by typing into the search box above the table. This will instantly hide lines from the table that do not contain your search text.