HIV RT M184V
From
HIV
Mutant of: HIV RT (M184V)
HIV RT M184V
is a family RT enzyme
from
HIV.
"From the Los Alamos National Labs HIV Mutant database (now offline):|id:520|codon:ATG>GTG|drugs:1592U89
"From the Los Alamos National Labs HIV Mutant database (now offline):|id:521|codon:ATG>GTG|drugs:3TC
"From the Los Alamos National Labs HIV Mutant database (now offline):|id:522|codon:ATG>GTG|drugs:dOTC
"From the Los Alamos National Labs HIV Mutant database (now offline):|id:523|codon:ATG>GTG|drugs:ddC
"From the Los Alamos National Labs HIV Mutant database (now offline):|id:524|codon:ATG>GTG|drugs:ddI
From the Los Alamos National Labs HIV Mutant database (now offline):|id:525|codon:ATG>GTG|drugs:(-)dOTC|class:Nucleoside RT Inhibitor (NRTI)|notes:Selected in 15-20 passages
From the Los Alamos National Labs HIV Mutant database (now offline):|id:526|codon:ATG>GTG|drugs:(+)dOTC|class:Nucleoside RT Inhibitor (NRTI)|notes:6-7-fold resistance
From the Los Alamos National Labs HIV Mutant database (now offline):|id:527|codon:ATG>GTG|drugs:(-)dOTFC|class:Nucleoside RT Inhibitor (NRTI)|notes:high level resistance
From the Los Alamos National Labs HIV Mutant database (now offline):|id:528|codon:ATG>GTG|drugs:(+)dOTFC|class:Nucleoside RT Inhibitor (NRTI)|notes:high level resistance
"From the Los Alamos National Labs HIV Mutant database (now offline):|id:529|codon:ATG>GTG|drugs:(-)-FTC
From the Los Alamos National Labs HIV Mutant database (now offline):|id:530|codon:ATG>GTG|drugs:L-FddC|class:Nucleoside RT Inhibitor (NRTI)|notes:>100-fold resistant to 3TC-resistant virus
From the Los Alamos National Labs HIV Mutant database (now offline):|id:984|codon:TAT>TTT|drugs:VRX-329747|class:RT inhibitor|notes:This mutation also acts synergistically with K103N and Y181C to confer higher levels of resistance to DLV and EFV than seen with either of these mutations alone
From the Los Alamos National Labs HIV Mutant database (now offline):|id:991|codon:TAT>TTT|drugs:VRX-413638|class:RT inhibitor|notes:This mutation also acts synergistically with K103N and Y181C to confer higher levels of resistance to DLV and EFV than seen with either of these mutations alone
Selected Properties for HIV RT M184V: |
3'-5' exo activity | 5'-3' exo activity | Frameshift Rate | Substitution Rate | General Error Rate |
|---|---|---|---|---|---|
| no data | no data | no data | no data | no data |
- References (17)
- Structures (1)
- Sequences (0)
- Mutants (0)...
- Formulations (0)
- Polymerase Lots (0)
- External links
| Year | Authors | Title | Results by property |
|---|---|---|---|
| 2007 | Paul L Boyer, John G Julias, Zandrea Ambrose, Maqbool A Siddiqui, Victor E Marquez, Stephen H Hughes | The nucleoside analogs 4'C-methyl thy... | |
| 2006 | Zhijun Zhang, Michelle Walker, Wen Xu, Jae Hoon Shim, Jean-Luc Girardet, Robert K Hamatake, Zhi Hong | Novel nonnucleoside inhibitors that s... | |
| 2006 | Zhijun Zhang, Michelle Walker, Wen Xu, Jae Hoon Shim, Jean-Luc Girardet, Robert K Hamatake, Zhi Hong | Novel nonnucleoside inhibitors that s... | |
| 2002 | Phillip P Chamberlain, Jingshan Ren, Charles E Nichols, L Douglas, Johan Lennerstrand, Brendan A Larder, David I Stuart, David K Stammers | Crystal structures of Zidovudine- or ... | |
| 2002 | Janina Cramer, Michael Strerath, Andreas Marx, Tobias Restle | Exploring the effects of active site ... | RT,Associated condition,All properties |
| 2000 | N Richard, H Salomon, R Rando, T Mansour, T L Bowlin, Mark A. Wainberg | Selection and characterization of hum... | |
| 2000 | D L Taylor, P S Ahmed, A S Tyms, L J Wood, L A Kelly, P Chambers, J Clarke, J Bedard, T L Bowlin, R F Rando | Drug resistance and drug combination ... | |
| 2000 | N Richard, H Salomon, R Rando, T Mansour, T L Bowlin, Mark A. Wainberg | Selection and characterization of hum... | |
| 1999 | N Richar, Yudong Quan, H Salomon, M Hsu, J Bedard, P Richard Harrigan, R Rando, T Mansour, T L Bowlin, Mark A. Wainberg | Selection and characterization of HIV... | |
| 1997 | M Tisdale, T Alnadaf, D Cousens | Combination of mutations in human imm... | |
| 1994 | G Gosselin, Raymond F Schinazi, J P Sommadossi, C Mathé, M C Bergogne, A M Aubertin, A Kirn, J L Imbach | Anti-human immunodeficiency virus act... | |
| 1993 | Raymond F Schinazi, R M Lloyd, M H Nguyen, D L Cannon, A McMillan, N Ilksoy, Chung K Chu, Dennis C Liotta, Holly Z Bazmi, John W Mellors | Characterization of human immunodefic... | |
| 1993 | Q Gao, Z Gu, Michael A. Parniak, J Cameron, Nick Cammack, C Boucher, Mark A. Wainberg | The same mutation that encodes low-le... | |
| 1993 | M Tisdale, S D Kemp, N R Parry, Brendan A Larder | Rapid in vitro selection of human imm... | |
| 1992 | Q Gao, Z X Gu, Michael A. Parniak, X G Li, Mark A. Wainberg | In vitro selection of variants of hum... | |
| 1992 | Z Gu, Q Gao, Xincang Li, Michael A. Parniak, Mark A. Wainberg | Novel mutation in the human immunodef... | |
| 1992 | Z Gu, Q Gao, Xincang Li, Michael A. Parniak, Mark A. Wainberg | Novel mutation in the human immunodef... |
Protein information: search for HIV RT M184V at UniProt
Sequence information: