HIV RT M184V

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This page presents all the information in Polbase for HIV RT M184V.

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Mutant of: HIV RT (M184V)

HIV RT M184V is a family RT enzyme from HIV. "From the Los Alamos National Labs HIV Mutant database (now offline):|id:520|codon:ATG>GTG|drugs:1592U89 "From the Los Alamos National Labs HIV Mutant database (now offline):|id:521|codon:ATG>GTG|drugs:3TC "From the Los Alamos National Labs HIV Mutant database (now offline):|id:522|codon:ATG>GTG|drugs:dOTC "From the Los Alamos National Labs HIV Mutant database (now offline):|id:523|codon:ATG>GTG|drugs:ddC "From the Los Alamos National Labs HIV Mutant database (now offline):|id:524|codon:ATG>GTG|drugs:ddI From the Los Alamos National Labs HIV Mutant database (now offline):|id:525|codon:ATG>GTG|drugs:(-)dOTC|class:Nucleoside RT Inhibitor (NRTI)|notes:Selected in 15-20 passages From the Los Alamos National Labs HIV Mutant database (now offline):|id:526|codon:ATG>GTG|drugs:(+)dOTC|class:Nucleoside RT Inhibitor (NRTI)|notes:6-7-fold resistance From the Los Alamos National Labs HIV Mutant database (now offline):|id:527|codon:ATG>GTG|drugs:(-)dOTFC|class:Nucleoside RT Inhibitor (NRTI)|notes:high level resistance From the Los Alamos National Labs HIV Mutant database (now offline):|id:528|codon:ATG>GTG|drugs:(+)dOTFC|class:Nucleoside RT Inhibitor (NRTI)|notes:high level resistance "From the Los Alamos National Labs HIV Mutant database (now offline):|id:529|codon:ATG>GTG|drugs:(-)-FTC From the Los Alamos National Labs HIV Mutant database (now offline):|id:530|codon:ATG>GTG|drugs:L-FddC|class:Nucleoside RT Inhibitor (NRTI)|notes:>100-fold resistant to 3TC-resistant virus From the Los Alamos National Labs HIV Mutant database (now offline):|id:984|codon:TAT>TTT|drugs:VRX-329747|class:RT inhibitor|notes:This mutation also acts synergistically with K103N and Y181C to confer higher levels of resistance to DLV and EFV than seen with either of these mutations alone From the Los Alamos National Labs HIV Mutant database (now offline):|id:991|codon:TAT>TTT|drugs:VRX-413638|class:RT inhibitor|notes:This mutation also acts synergistically with K103N and Y181C to confer higher levels of resistance to DLV and EFV than seen with either of these mutations alone

Selected Properties for HIV RT M184V:

3'-5' exo activity 5'-3' exo activity Frameshift Rate Substitution Rate General Error Rate
no data no data no data no data no data
Year Authors Title Results by property
2007 Paul L Boyer, John G Julias, Zandrea Ambrose, Maqbool A Siddiqui, Victor E Marquez, Stephen H Hughes Boyer PL2007
2006 Zhijun Zhang, Michelle Walker, Wen Xu, Jae Hoon Shim, Jean-Luc Girardet, Robert K Hamatake, Zhi Hong Zhang Z2006
2006 Zhijun Zhang, Michelle Walker, Wen Xu, Jae Hoon Shim, Jean-Luc Girardet, Robert K Hamatake, Zhi Hong Zhang Z2006
2002 Phillip P Chamberlain, Jingshan Ren, Charles E Nichols, L Douglas, Johan Lennerstrand, Brendan A Larder, David I Stuart, David K Stammers Chamberlain PP2002
2002 Janina Cramer, Michael Strerath, Andreas Marx, Tobias Restle Cramer J2002 RT,Associated condition,All properties
2000 N Richard, H Salomon, R Rando, T Mansour, T L Bowlin, Mark A. Wainberg Richard N2000
2000 D L Taylor, P S Ahmed, A S Tyms, L J Wood, L A Kelly, P Chambers, J Clarke, J Bedard, T L Bowlin, R F Rando Taylor DL2000
2000 N Richard, H Salomon, R Rando, T Mansour, T L Bowlin, Mark A. Wainberg Richard N2000
1999 N Richar, Yudong Quan, H Salomon, M Hsu, J Bedard, P Richard Harrigan, R Rando, T Mansour, T L Bowlin, Mark A. Wainberg Richar N1999
1997 M Tisdale, T Alnadaf, D Cousens Tisdale M1997
1994 G Gosselin, Raymond F Schinazi, J P Sommadossi, C Mathé, M C Bergogne, A M Aubertin, A Kirn, J L Imbach Gosselin G1994
1993 Raymond F Schinazi, R M Lloyd, M H Nguyen, D L Cannon, A McMillan, N Ilksoy, Chung K Chu, Dennis C Liotta, Holly Z Bazmi, John W Mellors Schinazi RF1993
1993 Q Gao, Z Gu, Michael A. Parniak, J Cameron, Nick Cammack, C Boucher, Mark A. Wainberg Gao Q1993
1993 M Tisdale, S D Kemp, N R Parry, Brendan A Larder Tisdale M1993
1992 Q Gao, Z X Gu, Michael A. Parniak, X G Li, Mark A. Wainberg Gao Q1992
1992 Z Gu, Q Gao, Xincang Li, Michael A. Parniak, Mark A. Wainberg Gu Z1992
1992 Z Gu, Q Gao, Xincang Li, Michael A. Parniak, Mark A. Wainberg Gu Z1992
All Polymerases | 2 Results

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