Dme Pol delta

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Welcome to the Polymerase Page

This page presents all the information in Polbase for Dme Pol delta.

Mutants:

At the top of the page you'll find a map of all positions of known mutants. Text links to mutants and digestion products are listed in the Mutants section.

Structures/Sequence:

If available, a representative structure is displayed at the upper right. All known structures are listed in the Structures section.

External links:

Polbase polymerases are linked to UniProt and Genbank where possible. The UniProt search link directs you to a pre-constructed UniProt search containing relevant terms.

References:

All references that refer to this Polymerase are listed with their topics and paper's title in the References table.

Results:

All the results for this polymerase can be examined by following the "Results" link at the bottom of the page.

Help icons:

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Dme Pol delta is a family B enzyme from Drosophila melanogaster.

Selected Properties for Dme Pol delta:

3'-5' exo activity 5'-3' exo activity Frameshift Rate Substitution Rate General Error Rate
Yes (1) No (1) no data no data no data
Year Authors Title Results by property
1999 Masahiko Oshige, N Aoyagi, P V Harris, K C Burtis, Kengo Sakaguchi A new DNA polymerase species from Dro...
1995 C S Chiang, I. Robert Lehman Isolation and sequence determination ...
1994 N Aoyagi, S Matsuoka, A Furunobu, Akio Matsukage, Kengo Sakaguchi Drosophila DNA polymerase delta. Puri... Cloned or native,Full length or truncated,Isoelectric Point,3-5' exo,5-3' exo,Molecular Weight,All properties
1993 C S Chiang, P G Mitsis, I. Robert Lehman DNA polymerase delta from embryos of ...
1992 V M Peck, E W Gerner, A E Cress Delta-type DNA polymerase characteriz...
1990 Kazufumi Kuroda, R Kagiyama-Takahashi, T Shinomiya Immunoaffinity purification and prope...
1988 M E Reyland, I. Robert Lehman, Lawrence A Loeb Specificity of proofreading by the 3'...
Protein sequence:

Predicted Structure Model

Predicted model AlphaFold DB Not experimentally determined

This AlphaFold DB model is predicted and not an experimentally determined structure. View AlphaFold DB entry Download predicted model (.pdb)

Confidence legend (pLDDT)

AlphaFold DB colors residues by predicted confidence. Use high-confidence regions for structural context and treat low-confidence regions cautiously.

  • Very high (pLDDT > 90) Backbone and side chains are usually reliable.
  • Confident (pLDDT 70-90) Overall fold is usually reliable, but some local detail may shift.
  • Low (pLDDT 50-70) Use with caution; this region may be flexible or uncertain.
  • Very low (pLDDT < 50) Often disordered or not confidently placed.

Using Polbase tables:

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