Studies on the biochemical basis of spontaneous mutation. III. Rate model for DNA polymerase-effected nucleotide misincorporation.

Goodman MF, Gore WC, Muzyczka N, Bessman MJ
Journal of molecular biology (1974), Volume 88, Page 243
PubMed entry

Polymerases:

Topics:

Fidelity, Exonuclease Activity

One line summary:

Theoretical paper that demonstrates the importance of 3'-exonuclease activity on the fidelity of DNA replication by the T4 and other DNA polymerases with exonuclease proofreading activity.

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