Utilization of aminopurine deoxynucleoside triphosphate by mutator, antimutator and wild-type DNA polymerases of bacteriophage T4.

Genetics (1973), Volume 73, Page 137



Nucleotide Incorporation, Nucleotide Analogs / Template Lesions, Fidelity, Mutational Analysis

One line summary:

All three of T4 wildtype, T4 tsL141 (A737V, antimutator) and T4 tsL98 (S345P, mutator) DNA polymerases discriminate between adenine and 2-aminopurine, but antimutator (tsL141) incorporates the least of it into DNA.


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