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Reference: DNA polymerase family X: function, structure, and cellular roles.

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Polymerase Reference Property Result Context
Human Pol beta DNA polymerase family X: function, structure, and cellular roles. Molecular Weight 39kD
Human Pol beta DNA polymerase family X: function, structure, and cellular roles. 3-5' Exonuclease (proofreading) No
Human Pol beta DNA polymerase family X: function, structure, and cellular roles. 5-3' Exonuclease No
Human Pol beta DNA polymerase family X: function, structure, and cellular roles. Template lesions Bypasses Reaction: Nucleotide incorporation; Substrate: dCTP; DNA lesion: 8-oxo-dG
Human Pol beta DNA polymerase family X: function, structure, and cellular roles. Template lesions Bypasses Reaction: Nucleotide incorporation
Human Pol beta DNA polymerase family X: function, structure, and cellular roles. Template lesions Bypasses Reaction: Nucleotide incorporation
Human Pol beta DNA polymerase family X: function, structure, and cellular roles. Amino Acids Contacting Primer Tyr271
Human Pol beta DNA polymerase family X: function, structure, and cellular roles. Overall Error Rate 0.0005 errors/bp
Human Pol beta DNA polymerase family X: function, structure, and cellular roles. Overall Error Rate 0.0024 errors/bp
Human Pol beta DNA polymerase family X: function, structure, and cellular roles. Full length or truncated Full length
Human Pol beta DNA polymerase family X: function, structure, and cellular roles. Amino Acids Contacting Template Arg283 and Tyr271
Human Pol beta DNA polymerase family X: function, structure, and cellular roles. Other Important Residues Tyr271, Phe272, Asp276, and Asn279 = dNTP binding pocket; Tyr271 = important for both chemistry and dNTP binding, alters steady-state catalytic efficiency
Human Pol beta DNA polymerase family X: function, structure, and cellular roles. Amino Acids Contacting NTP Phe272, Asp276 and Asn279
Human Pol beta DNA polymerase family X: function, structure, and cellular roles. Strand Displacement Yes
Human Pol beta DNA polymerase family X: function, structure, and cellular roles. Associated condition I260M and K289M - Cancer
Human Pol lamba DNA polymerase family X: function, structure, and cellular roles. Terminal Transferase Yes
Human Pol lamba DNA polymerase family X: function, structure, and cellular roles. Molecular Weight 68kD
Human Pol lamba DNA polymerase family X: function, structure, and cellular roles. 3-5' Exonuclease (proofreading) No
Human Pol lamba DNA polymerase family X: function, structure, and cellular roles. 5-3' Exonuclease No
Human Pol lamba DNA polymerase family X: function, structure, and cellular roles. Template lesions Bypasses Reaction: Nucleotide incorporation; DNA lesion: 8-oxo-dG
Human Pol lamba DNA polymerase family X: function, structure, and cellular roles. Full length or truncated Full length
Human Pol lamba DNA polymerase family X: function, structure, and cellular roles. Vmax 2.1 /second Reaction: Nucleotide incorporation; Substrate: dNTPs
Human Pol lamba DNA polymerase family X: function, structure, and cellular roles. Other accessory protein(s) PCNA, CDK2/CyclinA
Human Pol lamba DNA polymerase family X: function, structure, and cellular roles. Gap Filling Yes
Human Pol mu DNA polymerase family X: function, structure, and cellular roles. Terminal Transferase Yes
Human Pol mu DNA polymerase family X: function, structure, and cellular roles. Molecular Weight 55kD
Human Pol mu DNA polymerase family X: function, structure, and cellular roles. 3-5' Exonuclease (proofreading) No
Human Pol mu DNA polymerase family X: function, structure, and cellular roles. 5-3' Exonuclease No
Human Pol mu DNA polymerase family X: function, structure, and cellular roles. Template lesions Bypasses Reaction: Nucleotide incorporation; DNA lesion: 8-oxo-dG
Human Pol mu DNA polymerase family X: function, structure, and cellular roles. Template lesions Bypasses Reaction: Nucleotide incorporation; DNA lesion: Apurinic/Apyrimidinic (AP) site
Human Pol mu DNA polymerase family X: function, structure, and cellular roles. Full length or truncated Full length
Human Pol mu DNA polymerase family X: function, structure, and cellular roles. Vmax 0.076 /second Reaction: Nucleotide incorporation; Substrate: dNTPs
Human Pol mu DNA polymerase family X: function, structure, and cellular roles. Gap Filling Yes

Using Polbase tables:

Sorting:

Tables may be sorted by clicking on any of the column titles. A second click reverses the sort order. <Ctrl> + click on the column titles to sort by more than one column (e.g. family then name).

Filtering:

It is also possible to filter the table by typing into the search box above the table. This will instantly hide lines from the table that do not contain your search text.