Human Pol mu
Welcome to the Polymerase Page
This page presents all the information in Polbase for Human Pol mu.
Mutants:At the top of the page you'll find a map of all positions of known mutants. Text links to mutants and digestion products are listed in the Mutants section.
Structures/Sequence:If available, a representative structure is displayed at the upper right. All known structures are listed in the Structures section.
External links:Polbase polymerases are linked to UniProt and Genbank where possible. The UniProt search link directs you to a pre-constructed UniProt search containing relevant terms.
References:All references that refer to this Polymerase are listed with their topics and paper's title in the References table.
Results:All the results for this polymerase can be examined by following the "Results" link at the bottom of the page.
Help icons:
The symbol in the upper-right corner of the page
links to this help text. The question mark icon is used everywhere to indicate that help is available.
- References (25)
- Structures (3)
- Sequences (1)
- Mutants (0)...
- Formulations (0)
- Polymerase Lots (0)
- External links
| Year | Authors | Title | Results by property |
|---|---|---|---|
| S Sharma, CM Helchowski, CE Canman | The roles of DNA polymerase ζ and the... | ||
| 2012 | Maria Jose Martin, Maria V Garcia-Ortiz, Veronica Esteban, Luis Blanco | Ribonucleotides and manganese ions im... | |
| 2012 | Shanen M Sherrer, Laura E Sanman, Cynthia X Xia, Eric R Bolin, Chanchal K Malik, Georgia Efthimiopoulos, Ashis K Basu, Zucai Suo | Kinetic Analysis of the Bypass of a B... | |
| 2012 | Yaofeng Zhao, Christian Biertümpfel, Mark T Gregory, Yue-Jin Hua, Fumio Hanaoka, Wei Wen Yang | Structural basis of human DNA polymer... | |
| 2012 | Ajay Ummat, Olga Rechkoblit, Rinku Jain, Jayati Roy Choudhury, Robert E Johnson, Timothy D Silverstein, Angeliki Buku, Samer Lone, Louise Prakash, Satya Prakash, Aneel K Aggarwal | Structural basis for cisplatin DNA da... | |
| 2012 | Takuro Matsumoto, Kaori Go, Mariko Hyodo, Kotaro Koiwai, So Maezawa, Takahide Hayano, Masahiro Suzuki, Osamu Koiwai | BRCT domain of DNA polymerase μ has D... | |
| 2010 | Romain Chayot, Anne Danckaert, Benjamin Montagne, Miria Ricchetti | Lack of DNA polymerase mu affects the... | |
| 2010 | Mark D Sutton | Coordinating DNA polymerase traffic d... | |
| 2010 | Jennifer Yamtich, Joann B Sweasy | DNA polymerase family X: function, st... | Full length or truncated,Gap fill,Terminal Transferase,3-5' exo,5-3' exo,Molecular Weight,Vmax,Template lesions,All properties |
| 2009 | Paula Andrade, María José Martín, Raquel Juárez, Francisco López de Saro, Luis Blanco | Limited terminal transferase in human... | |
| 2007 | Robert S Pitcher, Nigel C Brissett, Angel J Picher, Paula Andrade, Raquel Juarez, Darren Thompson, Gavin C Fox, Luis Blanco, Aidan J Doherty | Structure and function of a mycobacte... | Terminal Transferase,All properties |
| 2007 | Andrea F Moon, Miguel Garcia-Diaz, Vinod K Batra, William A Beard, Katarzyna Bebenek, Thomas A Kunkel, Samuel H Wilson, Lars C Pedersen | The X family portrait: structural ins... | |
| 2007 | Eugene F DeRose, Michael W Clarkson, Steven A Gilmore, Cristina J Galban, Ashutosh Tripathy, Jody M Havener, Geoffrey A Mueller, Dale A Ramsden, Robert E London, Andrew L Lee | Solution structure of polymerase mu's... | |
| 2006 | Raquel Juárez, José F Ruiz, Stephanie A Nick McElhinny, Dale A Ramsden, Luis Blanco | A specific loop in human DNA polymera... | |
| 2004 | Michelle P Roettger, Kevin A Fiala, Susmitha Sompalli, Yuxia Dong, Zucai Suo | Pre-steady-state kinetic studies of t... | |
| 2004 | Shay Covo, Luis Blanco, Zvi Livneh | Lesion bypass by human DNA polymerase... | |
| 2004 | José F Ruiz, Daniel Lucas, Esther García-Palomero, Ana I Saez, Manuel A González, Miguel A Piris, Antonio Bernad, Luis Blanco | Overexpression of human DNA polymeras... | |
| 2003 | José F Ruiz, Raquel Juárez, Miguel García-Díaz, Gloria Terrados, Angel J Picher, Sergio González-Barrera, Antonio R Fernández de Henestrosa, Luis Blanco | Lack of sugar discrimination by human... | |
| 2003 | Stephanie A Nick McElhinny, Dale A Ramsden | Polymerase mu is a DNA-directed DNA/R... | |
| 2003 | Jody M Havener, Stephanie A Nick McElhinny, Ekaterina Bassett, Michele Gauger, Dale A Ramsden, Stephen G Chaney | Translesion synthesis past platinum D... | |
| 2002 | Yongqing Zhang, Xiaoming Wu, Dongyu Guo, Olga Rechkoblit, John-Stephen Taylor, Nicholas E Geacintov, Zhengqiang Wang | Lesion bypass activities of human DNA... | |
| 2002 | Jean-Baptiste Duvauchelle, Luis Blanco, Robert P P Fuchs, Agnes M Cordonnier | Human DNA polymerase mu (Pol mu) exhi... | |
| 2001 | Yongqing Zhang, Xiaoming Wu, Fenghua Yuan, Zhongwen Xie, Zhengqiang Wang | Highly frequent frameshift DNA synthe... | Cloned or native,Tagged,Tag Name,Full length or truncated,3-5' exo,Molecular Weight,All properties |
| 2001 | Patricia J Gearhart, Richard D Wood | Emerging links between hypermutation ... | Associated condition,All properties |
| 2000 | Orlando Domínguez, José F Ruiz, Teresa Laín de Lera, Miguel García-Díaz, Manuel A González, Tomas Kirchhoff, Carlos Martínez-A, Antonio Bernad, Luis Blanco | DNA polymerase mu (Pol mu), homologou... | Cloned or native,Full length or truncated,Terminal Transferase,3-5' exo,Molecular Weight,All properties |
Predicted Structure Model
This AlphaFold DB model is predicted and not an experimentally determined structure. View AlphaFold DB entry Download predicted model (.pdb)
Confidence legend (pLDDT)
AlphaFold DB colors residues by predicted confidence. Use high-confidence regions for structural context and treat low-confidence regions cautiously.
- Very high (pLDDT > 90) Backbone and side chains are usually reliable.
- Confident (pLDDT 70-90) Overall fold is usually reliable, but some local detail may shift.
- Low (pLDDT 50-70) Use with caution; this region may be flexible or uncertain.
- Very low (pLDDT < 50) Often disordered or not confidently placed.
Protein information: Uniprot Q9NP87 search for Human Pol mu at UniProt
Sequence information: NCBI nucleotides European nucleotide archive
Predicted structure: AlphaFold DB entry AF-Q9NP87-F1