Evolution of DNA polymerase iota structure and function in eukaryotes.


Analysis of DNA polymerase iota (Pol iota) enzymic activity in ...
Analysis of DNA polymerase iota (Pol iota) enzymic activity in different classes of eukaryotes has shown that error-prone activity of this enzyme can be found only in mammals, and that it is completely absent from organisms that are at lower stages of development. It was supposed that the emergence of the error-prone Pol iota activity in mammals is caused by structural alteration of the active center. Possible functions of error-prone Pol iota in higher eukaryotes are discussed.




new topics/pols set partial results complete validated


No results available for this paper.

Entry validated by:

Using Polbase tables:


Tables may be sorted by clicking on any of the column titles. A second click reverses the sort order. <Ctrl> + click on the column titles to sort by more than one column (e.g. family then name).


It is also possible to filter the table by typing into the search box above the table. This will instantly hide lines from the table that do not contain your search text.