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Reference: DNA polymerization in the absence of exonucleolytic proofreading: in vivo and in vitro studies.
Polymerase | Reference | Property | Result | Context |
---|---|---|---|---|
T4 D189A | DNA polymerization in the absence of exonucleolytic proofreading: in vivo and in vitro studies. | Nucleotide Substitution Rate | 4 Mutation frequency (relative to WT) | Technique: ac forward mutational assay |
T4 D189A | DNA polymerization in the absence of exonucleolytic proofreading: in vivo and in vitro studies. | Nucleotide Substitution Rate | 1 Mutation frequency (relative to WT) | Technique: T4 rII 199oc reversion assay |
T4 D189A | DNA polymerization in the absence of exonucleolytic proofreading: in vivo and in vitro studies. | Nucleotide Substitution Rate | 1 Mutation frequency (relative to WT) | Technique: T4 rII P7oc reversion assay |
T4 E191A | DNA polymerization in the absence of exonucleolytic proofreading: in vivo and in vitro studies. | Nucleotide Substitution Rate | 5 Mutation frequency (relative to WT) | Technique: ac forward mutational assay |
T4 E191A | DNA polymerization in the absence of exonucleolytic proofreading: in vivo and in vitro studies. | Nucleotide Substitution Rate | 2 Mutation frequency (relative to WT) | Technique: T4 rII 199oc reversion assay |
T4 E191A | DNA polymerization in the absence of exonucleolytic proofreading: in vivo and in vitro studies. | Nucleotide Substitution Rate | 6 Mutation frequency (relative to WT) | Technique: T4 rII P7oc reversion assay |
T4 D189AE191A | DNA polymerization in the absence of exonucleolytic proofreading: in vivo and in vitro studies. | Nucleotide Substitution Rate | 16 Mutation frequency (relative to WT) | Technique: ac forward mutational assay |
T4 D189AE191A | DNA polymerization in the absence of exonucleolytic proofreading: in vivo and in vitro studies. | Nucleotide Substitution Rate | 11 Mutation frequency (relative to WT) | Technique: T4 rII 199oc reversion assay |
T4 D189AE191A | DNA polymerization in the absence of exonucleolytic proofreading: in vivo and in vitro studies. | Nucleotide Substitution Rate | 30 Mutation frequency (relative to WT) | Technique: T4 rII P7oc reversion assay |
T4 A89TD363N | DNA polymerization in the absence of exonucleolytic proofreading: in vivo and in vitro studies. | Nucleotide Substitution Rate | 74 Mutation frequency (relative to WT) | Technique: T4 rII 199oc reversion assay |
T4 A89TD363N | DNA polymerization in the absence of exonucleolytic proofreading: in vivo and in vitro studies. | Nucleotide Substitution Rate | 36 Mutation frequency (relative to WT) | Technique: ac forward mutational assay |
T4 D324G | DNA polymerization in the absence of exonucleolytic proofreading: in vivo and in vitro studies. | Nucleotide Substitution Rate | 280 Mutation frequency (relative to WT) | Technique: T4 rII P7oc reversion assay |
T4 D324G | DNA polymerization in the absence of exonucleolytic proofreading: in vivo and in vitro studies. | Nucleotide Substitution Rate | 63 Mutation frequency (relative to WT) | Technique: T4 rII 199oc reversion assay |
T4 D324G | DNA polymerization in the absence of exonucleolytic proofreading: in vivo and in vitro studies. | Nucleotide Substitution Rate | 56 Mutation frequency (relative to WT) | Technique: ac forward mutational assay |
T4 E191AD324G | DNA polymerization in the absence of exonucleolytic proofreading: in vivo and in vitro studies. | Nucleotide Substitution Rate | 650 Mutation frequency (relative to WT) | Technique: ac forward mutational assay |
T4 E191AD324G | DNA polymerization in the absence of exonucleolytic proofreading: in vivo and in vitro studies. | Nucleotide Substitution Rate | 514 Mutation frequency (relative to WT) | Technique: T4 rII 199oc reversion assay |
T4 E191AD324G | DNA polymerization in the absence of exonucleolytic proofreading: in vivo and in vitro studies. | Nucleotide Substitution Rate | 1800 errors/bp | Technique: T4 rII P7oc reversion assay |
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