A helix-destabilising protein from herpes simplex virus type I infected cells which specifically stimulates the virus induced DNA polymerase activity in vitro.

Bruce CB, Pearson CK
Biochem Biophys Res Commun (1983), Volume 116, Page 327
PubMed entry

Abstract:

We have isolated a protein fraction from HSV-1 infected cells which ...
We have isolated a protein fraction from HSV-1 infected cells which binds specifically to single-stranded DNA, facilitates a lowering of the melting temperature of poly[d(A-T)] and specifically stimulates the activity of the homologous virus-induced DNA-dependent DNA polymerase in vitro. These are major characteristics of a helix-destabilising protein, exemplified by the prokaryotic gene 32 protein.

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