Trisodium phosphonoformate, a new antiviral compound.

Helgstrand E, Eriksson B, Johansson NG, Lannerö B, Larsson A, Misiorny A, Norén JO, Sjöberg B, Stenberg K, Stening G, Stridh S, Oberg B
Science (1978), Volume 201, Page 819
PubMed entry

Abstract:

Trisodium phosphonoformate selectively inhibits cell-free DNA ...
Trisodium phosphonoformate selectively inhibits cell-free DNA polymerase activity induced by herpesvirus. The new inhibitor has an antiviral effect on herpes simplex virus types 1 and 2, pseudorables virus, and infectious bovine rhinotracheitis virus in cell culture. It has a good therapeutic activity against cutaneous herpes simplex virus infection in guinea pigs.

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