Insights into the cellular role of enigmatic DNA polymerase iota.

Abstract:

It has been a decade since the discovery of human DNA polymerase iota (poliota). Since that time, the enzyme has been characterized extensively at the biochemical level, but the cellular function of poliota remains enigmatic. Recent studies on poliota have, however, provided much needed insights into its biological role(s) and suggest that the enzyme plays important functions in protecting humans from the deleterious consequences of exposure to both oxidative- and ultraviolet light-induced DNA damage.

Polymerases:

Topics:

Status:

new topics/pols set partial results complete validated

Results:

No results available for this paper.

Entry validated by:

Log in to edit reference All References

Using Polbase tables:

Sorting:

Tables may be sorted by clicking on any of the column titles. A second click reverses the sort order. <Ctrl> + click on the column titles to sort by more than one column (e.g. family then name).

Filtering:

It is also possible to filter the table by typing into the search box above the table. This will instantly hide lines from the table that do not contain your search text.