SEMG-1 expression in early stage chronic lymphocytic leukemia.

Ahmed SU, Meklat F, Shahriar M, Zhang J, Mastulov S, Giannakouros T, Jewell A, Zhang Y, Lim SH
Cytotherapy (2009), Volume 11, Page 238
PubMed entry Publisher's site

Abstract:

Chronic lymphocytic leukemia (CLL) is an indolent disease. It is ...
Chronic lymphocytic leukemia (CLL) is an indolent disease. It is currently recommended that patients with CLL stages 0 and I follow a watchful waiting strategy. These patients are, therefore, a suitable group for testing immunotherapeutic approaches to avoid problems of immunosuppression as a result of disease progression and chemotherapy. In this study, we investigated the expression of SEMG-1 in early CLL to determine the suitability of SEMG-1 as a target for further development of tumor vaccines for early CLL.

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