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Doublié S

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Publications:

Title Authors Year Journal
Fluorescence resonance energy transfer studies of DNA polymerase β: the critical role of fingers domain movements and a novel non-covalent step during nucleotide selection. Doublié S 2014 The Journal of biological chemistry
Look Ma, no PCNA: how DNA polymerase ε synthesizes long stretches of DNA without a processivity factor. Doublié S 2014 Nature structural & molecular biology
A Crystallographic Study of the Role of Sequence Context in Thymine Glycol Bypass by a Replicative DNA Polymerase Serendipitously Sheds Light on the Exonuclease Complex. Doublié S 2011 Journal of molecular biology
Lesion bypass activity of DNA polymerase theta (POLQ) is an intrinsic property of the pol domain and depends on unique sequence inserts. Doublié S 2011 Journal of molecular biology
Phosphonoformic acid inhibits viral replication by trapping the closed form of the DNA polymerase. Doublié S 2011 The Journal of biological chemistry
Kinetics of mismatch formation opposite lesions by the replicative DNA polymerase from bacteriophage RB69. Doublié S 2010 Biochemistry
Crystal structure of a replicative DNA polymerase bound to the oxidized guanine lesion guanidinohydantoin. Doublié S 2010 Biochemistry
A structural rationale for stalling of a replicative DNA polymerase at the most common oxidative thymine lesion, thymine glycol. Doublié S 2007 Proceedings of the National Academy of Sciences of the United States of America
Structural and biochemical investigation of the role in proofreading of a beta hairpin loop found in the exonuclease domain of a replicative DNA polymerase of the B family. Doublié S 2007 The Journal of biological chemistry
Caught bending the A-rule: crystal structures of translesion DNA synthesis with a non-natural nucleotide. Doublié S 2007 Biochemistry
Bumps in the road: how replicative DNA polymerases see DNA damage. Doublié S 2005 Current opinion in structural biology
Structural basis for the dual coding potential of 8-oxoguanosine by a high-fidelity DNA polymerase. Doublié S 2004 The EMBO journal
Crystallographic snapshots of a replicative DNA polymerase encountering an abasic site. Doublié S 2004 The EMBO journal
Nucleotide insertion opposite a cis-syn thymine dimer by a replicative DNA polymerase from bacteriophage T7. Doublié S 2004 Nature structural & molecular biology
Crystal structure of mammalian poly(A) polymerase in complex with an analog of ATP. Doublié S 2000 The EMBO journal
An open and closed case for all polymerases. Doublié S 1999 Structure (London, England : 1993)
The motif D loop of human immunodeficiency virus type 1 reverse transcriptase is critical for nucleoside 5'-triphosphate selectivity. Doublié S 1999 The Journal of biological chemistry
Crystal structure of a bacteriophage T7 DNA replication complex at 2.2 A resolution. Doublié S 1998 Nature
The mechanism of action of T7 DNA polymerase. Doublié S 1998 Current opinion in structural biology
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