Structural and biochemical investigation of the role in proofreading of a beta hairpin loop found in the exonuclease domain of a replicative DNA polymerase of the B family.

Abstract:

Replicative DNA polymerases, as exemplified by the B family ...

Polymerases:

Topics:

Mutational Analysis, Kinetic Parameters, Structure and Structure/Function, Nucleotide Incorporation, Exonuclease Activity, Enzyme Substrate Interactions

Status:

new topics/pols set partial results complete validated

Results:

Polymerase Reference Property Result Context
RB69 Structural and biochemical investigation of the role in proofreading of a beta hairpin loop found in the exonuclease domain of a replicative DNA polymerase of the B family. 3-5' Exonuclease (proofreading) Yes

Entry validated by:

Structures:

2DTU