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Mullen GP

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Publications:

Title Authors Year Journal
Identification of small molecule synthetic inhibitors of DNA polymerase beta by NMR chemical shift mapping. Mullen GP 2004 The Journal of biological chemistry
Site-directed mutagenesis analysis of the structural interaction of the single-strand-break repair protein, X-ray cross-complementing group 1, with DNA polymerase beta. Mullen GP 2003 Nucleic acids research
1H, 13C and 15N resonance assignments for the perdeuterated 22 kD palm-thumb domain of DNA polymerase beta. Mullen GP 2002 J Biomol NMR
Mapping of the interaction interface of DNA polymerase beta with XRCC1. Mullen GP 2002 Structure (London, England : 1993)
1H, 15N, and 13C resonance assignments for a 20 kDa DNA polymerase from African swine fever virus. Mullen GP 2001 J Biomol NMR
Domain specific interaction in the XRCC1-DNA polymerase beta complex. Mullen GP 2000 Nucleic acids research
Backbone dynamics and refined solution structure of the N-terminal domain of DNA polymerase beta. Correlation with DNA binding and dRP lyase activity. Mullen GP 2000 Journal of molecular biology
Mapping of the 5'-2-deoxyribose-5-phosphate lyase active site in DNA polymerase beta by mass spectrometry. Mullen GP 2000 The Journal of biological chemistry
Functional analysis of the amino-terminal 8-kDa domain of DNA polymerase beta as revealed by site-directed mutagenesis. DNA binding and 5'-deoxyribose phosphate lyase activities. Mullen GP 1998 The Journal of biological chemistry
DNA polymerase beta in abasic site repair: a structurally conserved helix-hairpin-helix motif in lesion detection by base excision repair enzymes. Mullen GP 1997 Biochemistry
Three-dimensional solution structure of the N-terminal domain of DNA polymerase beta and mapping of the ssDNA interaction interface. Mullen GP 1996 Biochemistry
Solution structure of DNA polymerases and DNA polymerase-substrate complexes. Mullen GP 1995 Methods in enzymology
Assignments of 1H, 15N, and 13C resonances for the backbone and side chains of the N-terminal domain of DNA polymerase beta. Determination of the secondary structure and tertiary contacts. Mullen GP 1994 Biochemistry
Sequential proton NMR resonance assignments, circular dichroism, and structural properties of a 50-residue substrate-binding peptide from DNA polymerase I. Mullen GP 1993 Arch Biochem Biophys
NMR studies of the active site of DNA polymerase I and of a 50-residue peptide fragment of the enzyme. Mullen GP 1990 Biochem Pharmacol
Metal binding to DNA polymerase I, its large fragment, and two 3',5'-exonuclease mutants of the large fragment. Mullen GP 1990 The Journal of biological chemistry
Substrate and DNA binding to a 50-residue peptide fragment of DNA polymerase I. Comparison with the enzyme. Mullen GP 1989 The Journal of biological chemistry
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