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Focher F

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Publications:

Title Authors Year Journal
DNA synthesis enzymes and proliferating cell nuclear antigen in normal and neoplastic nerve cells. Focher F Anticancer research
Enantioselective binding of second generation pyrrolobenzoxazepinones to the catalytic ternary complex of HIV-1 RT wild-type and L100I and K103N drug resistant mutants. Focher F 2011 Bioorganic & medicinal chemistry letters
Anti-(herpes simplex virus) activity of 4'-thio-2'-deoxyuridines: a biochemical investigation for viral and cellular target enzymes. Focher F 2000 The Biochemical journal
Molecular basis for the antiviral and anticancer activities of unnatural L-beta-nucleosides. Focher F 1998 Expert opinion on investigational drugs
Stereospecificity of human DNA polymerases alpha, beta, gamma, delta and epsilon, HIV-reverse transcriptase, HSV-1 DNA polymerase, calf thymus terminal transferase and Escherichia coli DNA polymerase I in recognizing D- and L-thymidine 5'-triphosphate as substrate. Focher F 1995 Nucleic acids research
Lack of stereospecificity of some cellular and viral enzymes involved in the synthesis of deoxyribonucleotides and DNA: molecular basis for the antiviral activity of unnatural L-beta-nucleosides. Focher F 1995 Biochimie
Aphidicolin inhibits in vitro the activity of pseudorabies virus (PRV) DNA polymerase and in vivo the viral proliferation. Focher F 1994 In Vivo
Developmental activity profile of DNA polymerases delta and alpha in rat neurons suggests a coordinated in vivo function. Focher F 1992 In vivo (Athens, Greece)
Specific inhibition of human DNA ligase adenylation by a distamycin derivative possessing antitumor activity. Focher F 1991 Nucleic acids research
HP 0.35, a cephalosporin degradation product is a specific inhibitor of lentiviral RNAses H. Focher F 1991 Nucleic acids research
Activity profiles of enzymes that control the uracil incorporation into DNA during neuronal development. Focher F 1990 Mutation research
Effect of divalent and monovalent cations on calf thymus PCNA-independent DNA polymerase delta and its 3'----5' exonuclease. Focher F 1990 FEBS letters
Calf thymus DNA polymerase delta independent of proliferating cell nuclear antigen (PCNA). Focher F 1989 Nucleic acids research
Do DNA polymerases delta and alpha act coordinately as leading and lagging strand replicases? Focher F 1988 FEBS letters
Replication of single-stranded porcine circovirus DNA by DNA polymerases alpha and delta. Focher F 1988 Biochimica et biophysica acta
Calf thymus DNA polymerase delta: purification, biochemical and functional properties of the enzyme after its separation from DNA polymerase alpha, a DNA dependent ATPase and proliferating cell nuclear antigen. Focher F 1988 Nucleic acids research
Aphidicolin does not inhibit DNA repair synthesis in ultraviolet-irradiated HeLa cells. A radioautographic study. Focher F 1981 The Biochemical journal

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