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Matsuoka M

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Publications:

Title Authors Year Journal
Design of peptide-based inhibitors for human immunodeficiency virus type 1 strains resistant to T-20. Matsuoka M 2009 The Journal of biological chemistry
Clinical relevance of substitutions in the connection subdomain and RNase H domain of HIV-1 reverse transcriptase from a cohort of antiretroviral treatment-naïve patients. Matsuoka M 2009 Antiviral research
SC29EK, a peptide fusion inhibitor with enhanced alpha-helicity, inhibits replication of human immunodeficiency virus type 1 mutants resistant to enfuvirtide. Matsuoka M 2009 Antimicrobial agents and chemotherapy
Amino acid mutation N348I in the connection subdomain of human immunodeficiency virus type 1 reverse transcriptase confers multiclass resistance to nucleoside and nonnucleoside reverse transcriptase inhibitors. Matsuoka M 2008 J Virol
2'-deoxy-4'-C-ethynyl-2-halo-adenosines active against drug-resistant human immunodeficiency virus type 1 variants. Matsuoka M 2008 The international journal of biochemistry & cell biology
Activity against human immunodeficiency virus type 1, intracellular metabolism, and effects on human DNA polymerases of 4'-ethynyl-2-fluoro-2'-deoxyadenosine. Matsuoka M 2007 Antimicrob Agents Chemother
2'-Deoxy-4'-C-ethynyl-2-fluoroadenosine: a nucleoside reverse transcriptase inhibitor with highly potent activity against all HIV-1 strains, favorable toxic profiles and stability in plasma. Matsuoka M 2006 Nucleic Acids Symp Ser (Oxf)
Attempt to reduce cytotoxicity by synthesizing the L-enantiomer of 4'-C-ethynyl-2'-deoxypurine nucleosides as antiviral agents against HIV and HBV. Matsuoka M 2004 Antivir Chem Chemother
Design, efficient synthesis, and anti-HIV activity of 4'-C-cyano- and 4'-C-ethynyl-2'-deoxy purine nucleosides. Matsuoka M 2004 Nucleosides, nucleotides & nucleic acids
4'-Ethynyl nucleoside analogs: potent inhibitors of multidrug-resistant human immunodeficiency virus variants in vitro. Matsuoka M 2001 Antimicrob Agents Chemother
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