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Wright GE

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Publications:

Title Authors Year Journal
7-Alkyl-N(2)-substituted-3-deazaguanines. Synthesis, DNA polymerase III inhibition and antibacterial activity. Wright GE 2011 Bioorganic & medicinal chemistry letters
A method to assay inhibitors of DNA polymerase IIIC activity. Wright GE 2008 Methods Mol Med
Hybrid antibacterials. DNA polymerase-topoisomerase inhibitors. Wright GE 2006 J Med Chem
Synthesis of substituted 6-anilinouracils and their inhibition of DNA polymerase IIIC and Gram-positive bacterial growth. Wright GE 2003 J Med Chem
In vitro antimicrobial activities of novel anilinouracils which selectively inhibit DNA polymerase III of gram-positive bacteria. Wright GE 2000 Antimicrob Agents Chemother
Sensitivity of bacteriophage RB69 DNA polymerase to N2-(p-n-butylphenyl)-2'-deoxyguanosine nucleotides. Wright GE 1999 Nucleosides Nucleotides
Inhibitors of DNA polymerase III as novel antimicrobial agents against gram-positive eubacteria. Wright GE 1999 Antimicrob Agents Chemother
6-Anilinouracil-based inhibitors of Bacillus subtilis DNA polymerase III: antipolymerase and antimicrobial structure-activity relationships based on substitution at uracil N3. Wright GE 1999 J Med Chem
Analysis of inhibitors of bacteriophage T4 DNA polymerase. Wright GE 1994 Nucleic acids research
The molecular mechanism of inhibition of alpha-type DNA polymerases by N2-(butylphenyl)dGTP and 2-(butylanilino)dATP: variation in susceptibility to polymerization. Wright GE 1991 Nucleic acids research
Development of novel inhibitor probes of DNA polymerase III based on dGTP analogs of the HPUra type: base, nucleoside and nucleotide derivatives of N2-(3,4-dichlorobenzyl)guanine. Wright GE 1990 Nucleic acids research
A kinetic study of rat recombinant DNA polymerase beta: detection of a slow (hysteretic) transition in polymerase activity and inhibition by butylphenyl-deoxyguanosine triphosphate. Wright GE 1989 Nucleic acids research
Carbonyldiphosphonate, a selective inhibitor of mammalian DNA polymerase delta. Wright GE 1989 Biochemistry
Inhibitors of Bacillus subtilis DNA polymerase III. Influence of modifications in the pyrimidine ring of anilino- and (benzylamino)pyrimidines. Wright GE 1986 J Med Chem
Elucidation of the mechanism of selective inhibition of mammalian DNA polymerase alpha by 2-butylanilinopurines: development and characterization of 2-(p-n-butylanilino)adenine and its deoxyribonucleotides. Wright GE 1985 Nucleic acids research
Differential inhibition of human placental DNA polymerases delta and alpha by BuPdGTP and BuAdATP. Wright GE 1985 Nucleic acids research
Synthesis and characterization of N2-(p-n-butylphenyl)-2'-deoxyguanosine and its 5'-triphosphate and their inhibition of HeLa DNA polymerase alpha. Wright GE 1984 J Med Chem
Butylphenyl dGTP: a selective and potent inhibitor of mammalian DNA polymerase alpha. Wright GE 1984 Nucleic acids research
Quantitative structure-activity relationships of 6-anilinouracils as inhibitors of Bacillus subtilis DNA polymerase III. Wright GE 1984 J Med Chem
Design and characterization of N2-arylaminopurines which selectively inhibit replicative DNA synthesis and replication-specific DNA polymerases: guanine derivatives active on mammalian DNA polymerase alpha and bacterial DNA polymerase III. Wright GE 1982 Nucleic acids research
Butylanilinouracil: a selective inhibitor of HeLa cell DNA synthesis and HeLa cell DNA polymerase alpha. Wright GE 1980 Nucleic acids research
Inhibitors of Bacillus subtilis DNA polymerase III. 6-Anilinouracils and 6-(alkylamino)uracils. Wright GE 1980 J Med Chem
Inhibitors of Bacillus subtilis DNA polymerase III. 6-(arylalkylamino)uracils and 6-anilinouracils. Wright GE 1977 J Med Chem
Inhibitors of Bacillus subtilis DNA polymerase III. Structure-activity relationships of 6-(phenylhydrazino)uracils. Wright GE 1977 J Med Chem

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