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Hurwitz J

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Publications:

Title Authors Year Journal
Reconstitution of recombination-associated DNA synthesis with human proteins. Hurwitz J 2013 Nucleic acids research
Properties of the human Cdc45/Mcm2-7/GINS helicase complex and its action with DNA polymerase {varepsilon} in rolling circle DNA synthesis. Hurwitz J 2012 Proceedings of the National Academy of Sciences of the United States of America
Characterization of the DNA primase complex isolated from the archaeon, Thermococcus kodakaraensis. Hurwitz J 2012 The Journal of biological chemistry
A novel DNA nuclease is stimulated by association with the GINS complex. Hurwitz J 2011 Nucleic acids research
Studies on Human DNA Polymerase {epsilon} and GINS Complex and Their Role in DNA Replication. Hurwitz J 2011 The Journal of biological chemistry
DNA polymerase eta lacking the ubiquitin-binding domain promotes replicative lesion bypass in humans cells. Hurwitz J 2010 Proceedings of the National Academy of Sciences of the United States of America
Roles of PCNA-binding and ubiquitin-binding domains in human DNA polymerase eta in translesion DNA synthesis. Hurwitz J 2008 Proceedings of the National Academy of Sciences of the United States of America
Crystal structure of the GINS complex and functional insights into its role in DNA replication. Hurwitz J 2007 Proceedings of the National Academy of Sciences of the United States of America
Fission yeast Mcm10p contains primase activity. Hurwitz J 2006 The Journal of biological chemistry
Isolation of human Dna2 endonuclease and characterization of its enzymatic properties. Hurwitz J 2006 Nucleic acids research
The discovery of RNA polymerase. Hurwitz J 2005 The Journal of biological chemistry
A single domain in human DNA polymerase iota mediates interaction with PCNA: implications for translesion DNA synthesis. Hurwitz J 2005 Molecular and cellular biology
Primer utilization by DNA polymerase alpha-primase is influenced by its interaction with Mcm10p. Hurwitz J 2004 The Journal of biological chemistry
The alternative Ctf18-Dcc1-Ctf8-replication factor C complex required for sister chromatid cohesion loads proliferating cell nuclear antigen onto DNA. Hurwitz J 2003 Proceedings of the National Academy of Sciences of the United States of America
Stimulation of DNA synthesis activity of human DNA polymerase kappa by PCNA. Hurwitz J 2002 Molecular and cellular biology
The influence of the Cdc27 subunit on the properties of the Schizosaccharomyces pombe DNA polymerase delta. Hurwitz J 2002 The Journal of biological chemistry
Targeting of human DNA polymerase iota to the replication machinery via interaction with PCNA. Hurwitz J 2001 Proceedings of the National Academy of Sciences of the United States of America
Physical and functional interactions of human DNA polymerase eta with PCNA. Hurwitz J 2001 Molecular and cellular biology
In vitro reconstitution of the Schizosaccharomyces pombe alternative excision repair pathway. Hurwitz J 2000 Biochemistry
Dynamics of beta and proliferating cell nuclear antigen sliding clamps in traversing DNA secondary structure. Hurwitz J 2000 The Journal of biological chemistry
Fidelity of eucaryotic DNA polymerase delta holoenzyme from Schizosaccharomyces pombe. Hurwitz J 2000 The Journal of biological chemistry
Structure and activity associated with multiple forms of Schizosaccharomyces pombe DNA polymerase delta. Hurwitz J 2000 The Journal of biological chemistry
A unique organization of the protein subunits of the DNA polymerase clamp loader in the archaeon Methanobacterium thermoautotrophicum deltaH. Hurwitz J 2000 The Journal of biological chemistry
Species specificity of human RPA in simian virus 40 DNA replication lies in T-antigen-dependent RNA primer synthesis. Hurwitz J 2000 Nucleic acids research
The C-terminal region of Schizosaccaromyces pombe proliferating cell nuclear antigen is essential for DNA polymerase activity. Hurwitz J 1999 Proceedings of the National Academy of Sciences of the United States of America
Isolation and characterization of a split B-type DNA polymerase from the archaeon Methanobacterium thermoautotrophicum deltaH. Hurwitz J 1999 The Journal of biological chemistry
Multiple competition reactions for RPA order the assembly of the DNA polymerase delta holoenzyme. Hurwitz J 1999 The EMBO journal
Reconstitution of proliferating cell nuclear antigen-dependent repair of apurinic/apyrimidinic sites with purified human proteins. Hurwitz J 1999 The Journal of biological chemistry
Studies on the interactions between human replication factor C and human proliferating cell nuclear antigen. Hurwitz J 1999 Proceedings of the National Academy of Sciences of the United States of America
Processivity of DNA polymerases: two mechanisms, one goal. Hurwitz J 1998 Structure (London, England : 1993)
ATP hydrolysis catalyzed by human replication factor C requires participation of multiple subunits. Hurwitz J 1998 Proceedings of the National Academy of Sciences of the United States of America
A complex consisting of human replication factor C p40, p37, and p36 subunits is a DNA-dependent ATPase and an intermediate in the assembly of the holoenzyme. Hurwitz J 1997 The Journal of biological chemistry
The influence of the proliferating cell nuclear antigen-interacting domain of p21(CIP1) on DNA synthesis catalyzed by the human and Saccharomyces cerevisiae polymerase delta holoenzymes. Hurwitz J 1997 The Journal of biological chemistry
DNA polymerase delta isolated from Schizosaccharomyces pombe contains five subunits. Hurwitz J 1997 Proceedings of the National Academy of Sciences of the United States of America
The large subunit of replication factor C is a substrate for caspase-3 in vitro and is cleaved by a caspase-3-like protease during Fas-mediated apoptosis. Hurwitz J 1997 The EMBO journal
Transcription-positive cofactor 4 forms complexes with HSSB (RPA) on single-stranded DNA and influences HSSB-dependent enzymatic synthesis of simian virus 40 DNA. Hurwitz J 1996 The Journal of biological chemistry
Reconstitution of human replication factor C from its five subunits in baculovirus-infected insect cells. Hurwitz J 1996 Proceedings of the National Academy of Sciences of the United States of America
Structure of the C-terminal region of p21(WAF1/CIP1) complexed with human PCNA. Hurwitz J 1996 Cell
In vitro reconstitution of human replication factor C from its five subunits. Hurwitz J 1996 Proceedings of the National Academy of Sciences of the United States of America
Assignment of the 36.5-kDa (RFC5), 37-kDa (RFC4), 38-kDa (RFC3), and 40-kDa (RFC2) subunit genes of human replication factor C to chromosome bands 12q24.2-q24.3, 3q27, 13q12.3-q13, and 7q11.23. Hurwitz J 1995 Genomics
Cell-cycle inhibition by independent CDK and PCNA binding domains in p21Cip1. Hurwitz J 1995 Nature
Replication of bovine papillomavirus type 1 origin-containing DNA in crude extracts and with purified proteins. Hurwitz J 1994 The Journal of biological chemistry
Initiation of DNA replication by simian virus 40 T antigen is inhibited by the p107 protein. Hurwitz J 1994 The Journal of biological chemistry
Cdk-interacting protein 1 directly binds with proliferating cell nuclear antigen and inhibits DNA replication catalyzed by the DNA polymerase delta holoenzyme. Hurwitz J 1994 Proceedings of the National Academy of Sciences of the United States of America
The subunits of activator 1 (replication factor C) carry out multiple functions essential for proliferating-cell nuclear antigen-dependent DNA synthesis. Hurwitz J 1993 Proceedings of the National Academy of Sciences of the United States of America
Functional interactions between SV40 T antigen and other replication proteins at the replication fork. Hurwitz J 1993 The Journal of biological chemistry
DNA polymerase alpha stimulates the ATP-dependent binding of simian virus tumor T antigen to the SV40 origin of replication. Hurwitz J 1993 The Journal of biological chemistry
Studies of the cloned 37-kDa subunit of activator 1 (replication factor C) of HeLa cells. Hurwitz J 1992 Proceedings of the National Academy of Sciences of the United States of America
The replication of DNA containing the simian virus 40 origin by the monopolymerase and dipolymerase systems. Hurwitz J 1992 The Journal of biological chemistry
Sequence and expression in Escherichia coli of the 40-kDa subunit of activator 1 (replication factor C) of HeLa cells. Hurwitz J 1992 Proceedings of the National Academy of Sciences of the United States of America
Studies on the initiation of simian virus 40 replication in vitro: RNA primer synthesis and its elongation. Hurwitz J 1992 Proceedings of the National Academy of Sciences of the United States of America
Synthesis of DNA by DNA polymerase epsilon in vitro. Hurwitz J 1991 The Journal of biological chemistry
Influence of poly(ADP-ribose) polymerase on the enzymatic synthesis of SV40 DNA. Hurwitz J 1991 The Journal of biological chemistry
Studies on the activator 1 protein complex, an accessory factor for proliferating cell nuclear antigen-dependent DNA polymerase delta. Hurwitz J 1991 The Journal of biological chemistry
Mechanism of elongation of primed DNA by DNA polymerase delta, proliferating cell nuclear antigen, and activator 1. Hurwitz J 1990 Proceedings of the National Academy of Sciences of the United States of America
Studies on the initiation and elongation reactions in the simian virus 40 DNA replication system. Hurwitz J 1990 Proceedings of the National Academy of Sciences of the United States of America
Multiple functions of human single-stranded-DNA binding protein in simian virus 40 DNA replication: single-strand stabilization and stimulation of DNA polymerases alpha and delta. Hurwitz J 1989 Proceedings of the National Academy of Sciences of the United States of America
Synthesis of DNA containing the simian virus 40 origin of replication by the combined action of DNA polymerases alpha and delta. Hurwitz J 1989 Proceedings of the National Academy of Sciences of the United States of America
Studies on the DNA elongation inhibitor and its proliferating cell nuclear antigen-dependent control in simian virus 40 DNA replication in vitro. Hurwitz J 1989 Proceedings of the National Academy of Sciences of the United States of America
Studies on the role of the phi X174 gene A protein in phi X viral strand synthesis. I. Replication of DNA containing an alteration in position 1 of the 30-nucleotide icosahedral bacteriophage origin. Hurwitz J 1988 The Journal of biological chemistry
Complete enzymatic synthesis of DNA containing the SV40 origin of replication. Hurwitz J 1988 The Journal of biological chemistry
Initiation of adenovirus DNA replication. II. Structural requirements using synthetic oligonucleotide adenovirus templates. Hurwitz J 1988 The Journal of biological chemistry
Initiation of adenovirus DNA replication. I. Mechanism of action of a host protein required for replication of adenovirus DNA templates devoid of the terminal protein. Hurwitz J 1988 The Journal of biological chemistry
Studies on the role of the phi X174 gene A protein in phi X viral strand synthesis. II. Effects of DNA replication of mutations in the 30-nucleotide icosahedral bacteriophage origin. Hurwitz J 1988 The Journal of biological chemistry
In vitro replication of DNA containing either the SV40 or the polyoma origin. Hurwitz J 1987 Philosophical transactions of the Royal Society of London. Series B, Biological sciences
Replication of simian virus 40 origin-containing DNA in vitro with purified proteins. Hurwitz J 1987 Proceedings of the National Academy of Sciences of the United States of America
Unwinding of duplex DNA from the SV40 origin of replication by T antigen. Hurwitz J 1987 Science (New York, N.Y.)
Role of DNA polymerase alpha and DNA primase in simian virus 40 DNA replication in vitro. Hurwitz J 1986 Proceedings of the National Academy of Sciences of the United States of America
Species-specific in vitro synthesis of DNA containing the polyoma virus origin of replication. Hurwitz J 1986 Proceedings of the National Academy of Sciences of the United States of America
The adenovirus DNA binding protein and adenovirus DNA polymerase interact to catalyze elongation of primed DNA templates. Hurwitz J 1986 The Journal of biological chemistry
Expression in Escherichia coli of a fusion protein product containing a region of the adenovirus DNA polymerase. Hurwitz J 1985 Proceedings of the National Academy of Sciences of the United States of America
Protein-primed replication of plasmids containing the terminus of the adenovirus genome. II. Purification and characterization of a host protein required for the replication of DNA templates devoid of the terminal protein. Hurwitz J 1984 The Journal of biological chemistry
Protein-primed replication of plasmids containing the terminus of the adenovirus genome. I. Characterization of an in vitro DNA replication system dependent on adenoviral DNA sequences. Hurwitz J 1984 The Journal of biological chemistry
Purification of a primase activity associated with DNA polymerase alpha from HeLa cells. Hurwitz J 1984 The Journal of biological chemistry
DNA sequences required for the in vitro replication of adenovirus DNA. Hurwitz J 1984 Proceedings of the National Academy of Sciences of the United States of America
Properties of the adenovirus DNA polymerase. Hurwitz J 1984 The Journal of biological chemistry
Evidence for an altered adenovirus DNA polymerase in cells infected with the mutant H5ts149. Hurwitz J 1983 Proceedings of the National Academy of Sciences of the United States of America
Adenovirus DNA replication in vitro: synthesis of full-length DNA with purified proteins. Hurwitz J 1983 Proceedings of the National Academy of Sciences of the United States of America
Adenoviral protein-primed initiation of DNA chains in vitro. Hurwitz J 1982 Proceedings of the National Academy of Sciences of the United States of America
Adenovirus DNA replication in vitro: identification of a host factor that stimulates synthesis of the preterminal protein-dCMP complex. Hurwitz J 1982 Proceedings of the National Academy of Sciences of the United States of America
Separation of the adenovirus terminal protein precursor from its associated DNA polymerase: role of both proteins in the initiation of adenovirus DNA replication. Hurwitz J 1982 Proceedings of the National Academy of Sciences of the United States of America
Adenovirus DNA replication in vitro: purification of the terminal protein in a functional form. Hurwitz J 1981 Proceedings of the National Academy of Sciences of the United States of America
Replication of adenovirus DNA-protein complex with purified proteins. Hurwitz J 1981 Proceedings of the National Academy of Sciences of the United States of America
Elongation of primed DNA templates by eukaryotic DNA polymerases. Hurwitz J 1980 Proceedings of the National Academy of Sciences of the United States of America
In vitro DNA replication of recombinant plasmid DNAs containing the origin of progeny replicative form DNA synthesis of phage phi X174. Hurwitz J 1980 Proceedings of the National Academy of Sciences of the United States of America
Initiation of DNA replication by the dnaG protein. Hurwitz J 1980 The Journal of biological chemistry
Role of polymeric forms of the bacteriophage phi X174 coded gene A protein in phi XRFI DNA cleavage. Hurwitz J 1979 The Journal of biological chemistry
Selective inhibition of in vitro DNA synthesis dependent on phiX174 compared with fd DNA. I. Protein requirements for selective inhibition. Hurwitz J 1977 The Journal of biological chemistry
Selective inhibition of phiX RFII compared with fd RFII DNA synthesis in vitro. II. Resolution of discrimination reaction into multiple steps. Hurwitz J 1977 The Journal of biological chemistry
Involvement of escherichia coli dnaZ gene product in DNA elongation in vitro. Hurwitz J 1976 Proceedings of the National Academy of Sciences of the United States of America
RNA-dependent DNA polymerase activity of RNA tumor viruses. V. Rous sarcoma virus single-stranded RNA-DNA covalent hybrids in infected chicken embryo fibroblast cells. Hurwitz J 1975 Journal of virology
Association of phiX174 DNA-dependent ATPase activity with an Escherichia coli protein, replication factor Y, required for in vitro synthesis of phiX174 DNA. Hurwitz J 1975 Proceedings of the National Academy of Sciences of the United States of America
RNA-dependent DNA polymerase from avian myeloblastosis virus. Hurwitz J 1974 Methods in enzymology
Conversion of phiX174 viral DNA to double-stranded form by purified Escherichia coli proteins. Hurwitz J 1974 Proceedings of the National Academy of Sciences of the United States of America
Involvement of two protein factors and ATP in in vitro DNA synthesis catalyzed by DNA polymerase 3 of Escherichia coli. Hurwitz J 1974 Proceedings of the National Academy of Sciences of the United States of America
Mechanism of action of ribonuclease H isolated from avian myeloblastosis virus and Escherichia coli. Hurwitz J 1973 Proceedings of the National Academy of Sciences of the United States of America
Studies on in vitro DNA synthesis. II. Isolation of a protein which stimulates deoxynucleotide incorporation catalyzed by DNA polymerase of E. coli. Hurwitz J 1973 Biochemical and biophysical research communications
Studies on in vitro DNA synthesis. Purification of the dna G gene product from Escherichia coli. Hurwitz J 1973 Proceedings of the National Academy of Sciences of the United States of America
RNA-dependent DNA polymerase activity of RNA tumor viruses. I. Directing influence of DNA in the reaction. Hurwitz J 1972 Journal of virology
Conversion of phiX174 and fd single-stranded DNA to replicative forms in extracts of Escherichia coli. Hurwitz J 1972 Proceedings of the National Academy of Sciences of the United States of America
RNA-dependent DNA polymerase activity of RNA tumor viruses. II. Directing influence of RNA in the reaction. Hurwitz J 1972 Journal of virology
The enzymatic repair of DNA. I. Formation of circular lambda-DNA. Hurwitz J 1967 Proceedings of the National Academy of Sciences of the United States of America
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