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Canitrot Y

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Publications:

Title Authors Year Journal
The R438W polymorphism of human DNA polymerase lambda triggers cellular sensitivity to camptothecin by compromising the homologous recombination repair pathway. Canitrot Y 2010 Carcinogenesis
Regulation of DNA polymerase beta by the LMP1 oncoprotein of EBV through the nuclear factor-kappaB pathway. Canitrot Y 2009 Cancer research
Characterization of a natural mutator variant of human DNA polymerase lambda which promotes chromosomal instability by compromising NHEJ. Canitrot Y 2009 PloS one
Involvement of DNA polymerase mu in the repair of a specific subset of DNA double-strand breaks in mammalian cells. Canitrot Y 2007 Nucleic acids research
The DNA polymerase lambda is required for the repair of non-compatible DNA double strand breaks by NHEJ in mammalian cells. Canitrot Y 2006 Nucleic acids research
Enhanced expression and activity of DNA polymerase beta in chronic myelogenous leukemia. Canitrot Y 2006 Anticancer Res
Modulation of cellular response to cisplatin by a novel inhibitor of DNA polymerase beta. Canitrot Y 2005 Mol Pharmacol
DNA polymerase beta overexpression stimulates the Rad51-dependent homologous recombination in mammalian cells. Canitrot Y 2004 Nucleic acids research
Deregulated DNA polymerase beta strengthens ionizing radiation-induced nucleotidic and chromosomal instabilities. Canitrot Y 2002 Oncogene
Deregulated DNA polymerase beta induces chromosome instability and tumorigenesis. Canitrot Y 2002 Cancer research
DNA polymerase beta imbalance increases apoptosis and mutagenesis induced by oxidative stress. Canitrot Y 2001 FEBS letters
Enhanced expression and activity of DNA polymerase beta in human ovarian tumor cells: impact on sensitivity towards antitumor agents. Canitrot Y 2001 Oncogene
Nucleotide excision repair DNA synthesis by excess DNA polymerase beta: a potential source of genetic instability in cancer cells. Canitrot Y 2000 The FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Overexpression of DNA polymerase beta: a genomic instability enhancer process. Canitrot Y 1999 FASEB J
Mutator phenotype of BCR--ABL transfected Ba/F3 cell lines and its association with enhanced expression of DNA polymerase beta. Canitrot Y 1999 Oncogene
Overexpression of DNA polymerase beta in cell results in a mutator phenotype and a decreased sensitivity to anticancer drugs. Canitrot Y 1998 Proceedings of the National Academy of Sciences of the United States of America

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