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Sayer JM

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Publications:

Title Authors Year Journal
A structural gap in Dpo4 supports mutagenic bypass of a major benzo[a]pyrene dG adduct in DNA through template misalignment. Sayer JM 2007 Proceedings of the National Academy of Sciences of the United States of America
Structure of DNA polymerase beta with a benzo[c]phenanthrene diol epoxide-adducted template exhibits mutagenic features. Sayer JM 2006 Proceedings of the National Academy of Sciences of the United States of America
Error-prone translesion synthesis by human DNA polymerase eta on DNA-containing deoxyadenosine adducts of 7,8-dihydroxy-9,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene. Sayer JM 2005 The Journal of biological chemistry
Crystal structure of a benzo[a]pyrene diol epoxide adduct in a ternary complex with a DNA polymerase. Sayer JM 2004 Proceedings of the National Academy of Sciences of the United States of America
Nucleotide incorporation by human DNA polymerase gamma opposite benzo[a]pyrene and benzo[c]phenanthrene diol epoxide adducts of deoxyguanosine and deoxyadenosine. Sayer JM 2004 Nucleic acids research
Preferential misincorporation of purine nucleotides by human DNA polymerase eta opposite benzo[a]pyrene 7,8-diol 9,10-epoxide deoxyguanosine adducts. Sayer JM 2002 The Journal of biological chemistry
Structures of HIV-1 reverse transcriptase with pre- and post-translocation AZTMP-terminated DNA. Sayer JM 2002 The EMBO journal
Translesion replication of benzo[a]pyrene and benzo[c]phenanthrene diol epoxide adducts of deoxyadenosine and deoxyguanosine by human DNA polymerase iota. Sayer JM 2002 Nucleic acids research
Benzo[a]pyrene diol epoxide-deoxyguanosine adducts are accurately bypassed by yeast DNA polymerase zeta in vitro. Sayer JM 2002 Mutation research
Cross-linking of the fingers subdomain of human immunodeficiency virus type 1 reverse transcriptase to template-primer. Sayer JM 2001 Journal of virology
Incorporation of 4-thiothymidine into DNA by the Klenow fragment and HIV-1 reverse transcriptase. Sayer JM 2000 Bioorganic & medicinal chemistry letters
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