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White KL

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Publications:

Title Authors Year Journal
Mechanism of resistance to GS-9148 conferred by the Q151L mutation in HIV-1 reverse transcriptase. White KL 2011 Antimicrobial agents and chemotherapy
Visualizing the molecular interactions of a nucleotide analog, GS-9148, with HIV-1 reverse transcriptase-DNA complex. White KL 2010 Journal of molecular biology
Structural basis for the role of the K65R mutation in HIV-1 reverse transcriptase polymerization, excision antagonism, and tenofovir resistance. White KL 2009 The Journal of biological chemistry
Effects of the translocation status of human immunodeficiency virus type 1 reverse transcriptase on the efficiency of excision of tenofovir. White KL 2007 Antimicrob Agents Chemother
The K65R reverse transcriptase mutation in HIV-1 reverses the excision phenotype of zidovudine resistance mutations. White KL 2006 Antivir Ther
A combination of decreased NRTI incorporation and decreased excision determines the resistance profile of HIV-1 K65R RT. White KL 2005 Aids
Molecular mechanisms of tenofovir resistance conferred by human immunodeficiency virus type 1 reverse transcriptase containing a diserine insertion after residue 69 and multiple thymidine analog-associated mutations. White KL 2004 Antimicrob Agents Chemother
Mechanistic basis for reduced viral and enzymatic fitness of HIV-1 reverse transcriptase containing both K65R and M184V mutations. White KL 2004 The Journal of biological chemistry
Structures of HIV-1 RT-DNA complexes before and after incorporation of the anti-AIDS drug tenofovir. White KL 2004 Nature structural & molecular biology
Molecular mechanisms of resistance to human immunodeficiency virus type 1 with reverse transcriptase mutations K65R and K65R+M184V and their effects on enzyme function and viral replication capacity. White KL 2002 Antimicrob Agents Chemother
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