Visualizing the molecular interactions of a nucleotide analog, GS-9148, with HIV-1 reverse transcriptase-DNA complex.

Abstract:

GS-9148 ...

Polymerases:

Topics:

Nucleotide Analogs / Template Lesions, Structure and Structure/Function, Nucleotide Incorporation, Reverse Transcriptase, Source / Purification

Status:

new topics/pols set partial results complete validated

Results:

Polymerase Reference Property Result Context
HIV RT Visualizing the molecular interactions of a nucleotide analog, GS-9148, with HIV-1 reverse transcriptase-DNA complex. Reverse Transcriptase Activity Yes
HIV RT Visualizing the molecular interactions of a nucleotide analog, GS-9148, with HIV-1 reverse transcriptase-DNA complex. Polymerase Catalytic Residue Amino Acids D110, D185, D186
HIV RT Visualizing the molecular interactions of a nucleotide analog, GS-9148, with HIV-1 reverse transcriptase-DNA complex. Incorporation of non-standard nucleotides Unspecified
HIV RT Visualizing the molecular interactions of a nucleotide analog, GS-9148, with HIV-1 reverse transcriptase-DNA complex. Cloned or native Cloned in E. coli
HIV RT Visualizing the molecular interactions of a nucleotide analog, GS-9148, with HIV-1 reverse transcriptase-DNA complex. Tagged Yes
HIV RT Visualizing the molecular interactions of a nucleotide analog, GS-9148, with HIV-1 reverse transcriptase-DNA complex. Tag Name his
HIV RT Visualizing the molecular interactions of a nucleotide analog, GS-9148, with HIV-1 reverse transcriptase-DNA complex. Residues Involved in Catalysis of RNase H D443, E478, D498, D549
HIV RT Visualizing the molecular interactions of a nucleotide analog, GS-9148, with HIV-1 reverse transcriptase-DNA complex. Full length or truncated Full length

Structures:

3KK3 3KK2 3KK1 3KJV