Structural basis for the role of the K65R mutation in HIV-1 reverse transcriptase polymerization, excision antagonism, and tenofovir resistance.

Abstract:

K65R is a primary reverse transcriptase (RT) mutation selected in ...

Polymerases:

Topics:

Structure and Structure/Function, Reverse Transcriptase

Status:

new topics/pols set partial results complete validated

Results:

Polymerase Reference Property Result Context
HIV RT Structural basis for the role of the K65R mutation in HIV-1 reverse transcriptase polymerization, excision antagonism, and tenofovir resistance. Reverse Transcriptase Activity Yes
HIV RT K65R Structural basis for the role of the K65R mutation in HIV-1 reverse transcriptase polymerization, excision antagonism, and tenofovir resistance. Reverse Transcriptase Activity Yes

Entry validated by:

Structures:

3JYT 3JSM