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Kasai H

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Publications:

Title Authors Year Journal
Misreading of DNA templates containing 8-hydroxydeoxyguanosine at the modified base and at adjacent residues. Kasai H Nature
Establishment of immortalized human hepatocytes by introduction of HPV16 E6/E7 and hTERT as cell sources for liver cell-based therapy. Kasai H 2008 Cell transplantation
2-Hydroxy-2'-deoxyadenosine 5'-triphosphate enhances A.T --> C.G mutations caused by 8-hydroxy-2'-deoxyguanosine 5'-triphosphate by suppressing its degradation upon replication in a HeLa extract. Kasai H 2007 Biochemistry
Arg660Ser mutation in Thermus aquaticus DNA polymerase I suppresses T-->C transitions: implication of wobble base pair formation at the nucleotide incorporation step. Kasai H 2001 Nucleic acids research
2-Hydroxy-dATP is incorporated opposite G by Escherichia coli DNA polymerase III resulting in high mutagenicity. Kasai H 2000 Nucleic acids research
Incorporation of the guanosine triphosphate analogs 8-oxo-dGTP and 8-NH2-dGTP by reverse transcriptases and mammalian DNA polymerases. Kasai H 1997 The Journal of biological chemistry
Misincorporation of dAMP opposite 2-hydroxyadenine, an oxidative form of adenine. Kasai H 1995 Nucleic acids research
Formation of 2-hydroxydeoxyadenosine triphosphate, an oxidatively damaged nucleotide, and its incorporation by DNA polymerases. Steady-state kinetics of the incorporation. Kasai H 1995 The Journal of biological chemistry
8-Hydroxyguanine, an abundant form of oxidative DNA damage, causes G----T and A----C substitutions. Kasai H 1992 The Journal of biological chemistry

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