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Kaushik N

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Publications:

Title Authors Year Journal
Lysine 152 of MuLV reverse transcriptase is required for the integrity of the active site. Kaushik N 2002 Biochemistry
Mutational analysis of Lys65 of HIV-1 reverse transcriptase. Kaushik N 2000 Biochem J
The J-helix of Escherichia coli DNA polymerase I (Klenow fragment) regulates polymerase and 3'- 5'-exonuclease functions. Kaushik N 2000 The Journal of biological chemistry
A carboxylate triad is essential for the polymerase activity of Escherichia coli DNA polymerase I (Klenow fragment). Presence of two functional triads at the catalytic center. Kaushik N 2000 The Journal of biological chemistry
Role of glutamine 151 of human immunodeficiency virus type-1 reverse transcriptase in substrate selection as assessed by site-directed mutagenesis. Kaushik N 2000 Biochemistry
Role of Q190 of MuLV RT in ddNTP resistance and fidelity of DNA synthesis: a molecular model of interactions with substrates. Kaushik N 2000 Protein engineering
Valine of the YVDD motif of moloney murine leukemia virus reverse transcriptase: role in the fidelity of DNA synthesis. Kaushik N 2000 Biochemistry
Tyrosine 222, a member of the YXDD motif of MuLV RT, is catalytically essential and is a major component of the fidelity center. Kaushik N 1999 Biochemistry
Analysis of the role of glutamine 190 in the catalytic mechanism of murine leukemia virus reverse transcriptase. Kaushik N 1999 The Journal of biological chemistry
Phenotypic mechanism of HIV-1 resistance to 3'-azido-3'-deoxythymidine (AZT): increased polymerization processivity and enhanced sensitivity to pyrophosphate of the mutant viral reverse transcriptase. Kaushik N 1998 Biochemistry
Functional analysis of amino acid residues constituting the dNTP binding pocket of HIV-1 reverse transcriptase. Kaushik N 1998 The Journal of biological chemistry
Role of glutamine-151 of human immunodeficiency virus type-1 reverse transcriptase in RNA-directed DNA synthesis. Kaushik N 1997 Biochemistry
Role of methionine 184 of human immunodeficiency virus type-1 reverse transcriptase in the polymerase function and fidelity of DNA synthesis. Kaushik N 1996 Biochemistry
Significance of the O-helix residues of Escherichia coli DNA polymerase I in DNA synthesis: dynamics of the dNTP binding pocket. Kaushik N 1996 Biochemistry
Elucidation of the role of Arg 110 of murine leukemia virus reverse transcriptase in the catalytic mechanism: biochemical characterization of its mutant enzymes. Kaushik N 1996 Biochemistry
Biochemical analysis of catalytically crucial aspartate mutants of human immunodeficiency virus type 1 reverse transcriptase. Kaushik N 1996 Biochemistry
Glutamine 151 participates in the substrate dNTP binding function of HIV-1 reverse transcriptase. Kaushik N 1995 Biochemistry
Site-directed mutagenesis of arginine 72 of HIV-1 reverse transcriptase. Catalytic role and inhibitor sensitivity. Kaushik N 1995 The Journal of biological chemistry
Role of lysine 758 of Escherichia coli DNA polymerase I as assessed by site-directed mutagenesis. Kaushik N 1994 The Journal of biological chemistry
Photoaffinity labeling of DNA template-primer binding site in Escherichia coli DNA polymerase I. Identification of involved amino acids. Kaushik N 1994 The Journal of biological chemistry
Site directed mutagenesis of DNA polymerase I (Klenow) from Escherichia coli. The significance of Arg682 in catalysis. Kaushik N 1993 Eur J Biochem

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