| New DNA polymerase IIIC inhibitors: 3-subtituted anilinouracils with potent antibacterial activity in vitro and in vivo. |
Svenstrup N, Ehlert K, Ladel C, Kuhl A, Häbich D |
2008 |
| Synthesis, Biological Activity, and ADME Properties of Novel S-DABOs/N-DABOs as HIV Reverse Transcriptase Inhibitors. |
Radi M, Pagano M, Franchi L, Castagnolo D, Schenone S, Casaluce G, Zamperini C, Dreassi E, Maga G, Samuele A, Gonzalo E, Clotet B, Esté JA, Botta M |
2012 |
| N2-benzyloxycarbonylguan-9-yl acetic acid derivatives as HIV-1 reverse transcriptase non-nucleoside inhibitors with decreased loss of potency against common drug-resistance mutations. |
Adebambo KF, Zanoli S, Thomas MG, Cancio R, Howarth NM, Maga G |
2007 |
| Slow-, tight-binding HIV-1 reverse transcriptase non-nucleoside inhibitors highly active against drug-resistant mutants. |
Cancio R, Mai A, Rotili D, Artico M, Sbardella G, Clotet-Codina I, Esté JA, Crespan E, Zanoli S, Hübscher U, Spadari S, Maga G |
2007 |
| Arylthiopyrrole (AThP) derivatives as non-nucleoside HIV-1 reverse transcriptase inhibitors: synthesis, structure-activity relationships, and docking studies (part 2). |
Lavecchia A, Costi R, Artico M, Miele G, Novellino E, Bergamini A, Crespan E, Maga G, Di Santo R |
2006 |
| Arylthiopyrrole (AThP) derivatives as non-nucleoside HIV-1 reverse transcriptase inhibitors: synthesis, structure-activity relationships, and docking studies (part 1). |
Di Santo R, Costi R, Artico M, Miele G, Lavecchia A, Novellino E, Bergamini A, Cancio R, Maga G |
2006 |
| Design, synthesis, biological evaluation, and molecular modeling studies of TIBO-like cyclic sulfones as non-nucleoside HIV-1 reverse transcriptase inhibitors. |
Di Santo R, Costi R, Artico M, Ragno R, Lavecchia A, Novellino E, Gavuzzo E, La Torre F, Cirilli R, Cancio R, Maga G |
2006 |
| Substrate-induced stable enzyme-inhibitor complex formation allows tight binding of novel 2-aminopyrimidin-4(3H)-ones to drug-resistant HIV-1 reverse transcriptase mutants. |
Samuele A, Facchini M, Rotili D, Mai A, Artico M, Armand-Ugón M, Esté JA, Maga G |
2008 |
| A multidisciplinary approach for the identification of novel HIV-1 non-nucleoside reverse transcriptase inhibitors: S-DABOCs and DAVPs. |
Radi M, Falciani C, Contemori L, Petricci E, Maga G, Samuele A, Zanoli S, Terrazas M, Castria M, Togninelli A, Esté JA, Clotet-Codina I, Armand-Ugón M, Botta M |
2008 |
| Design, synthesis, and SAR of naphthyl-substituted Diarylpyrimidines as non-nucleoside inhibitors of HIV-1 reverse transcriptase. |
Liang YH, Feng XQ, Zeng ZS, Chen FE, Balzarini J, Pannecouque C, De Clercq E |
2009 |
| Synthesis and anti-HIV activity of aryl-2-[(4-cyanophenyl)amino]-4-pyrimidinone hydrazones as potent non-nucleoside reverse transcriptase inhibitors. |
Ma XD, Yang SQ, Gu SX, He QQ, Chen FE, De Clercq E, Balzarini J, Pannecouque C |
2011 |
| Synthesis and biological evaluation of 6-substituted 5-alkyl-2-(phenylaminocarbonylmethylthio)pyrimidin-4(3H)-ones as potent HIV-1 NNRTIs. |
Yu M, Li Z, Liu S, Fan E, Pannecouque C, De Clercq E, Liu X |
2011 |
| Lead optimization of diarylpyrimidines as non-nucleoside inhibitors of HIV-1 reverse transcriptase. |
Zeng ZS, Liang YH, Feng XQ, Chen FE, Pannecouque C, Balzarini J, De Clercq E |
2010 |
| Discovery of Piperidine-Linked Pyridine Analogues as Potent Non-nucleoside HIV-1 Reverse Transcriptase Inhibitors. |
Chen X, Li Y, Ding S, Balzarini J, Pannecouque C, De Clercq E, Liu H, Liu X |
2013 |
| Design, Synthesis, and Evaluation of WC5 Analogues as Inhibitors of Human Cytomegalovirus Immediate-Early 2 Protein, a Promising Target for Anti-HCMV Treatment. |
Massari S, Mercorelli B, Sancineto L, Sabatini S, Cecchetti V, Gribaudo G, Palù G, Pannecouque C, Loregian A, Tabarrini O |
2013 |