Bioorganic & medicinal chemistry

(Bioorg Med Chem) ISSNs: , 1464-3391

References in Bioorganic & medicinal chemistry:

Title Authors Year
Systematic synthesis of galloyl-substituted procyanidin B1 and B2, and their ability of DPPH radical scavenging activity and inhibitory activity of DNA polymerases. Saito A, Mizushina Y, Ikawa H, Yoshida H, Doi Y, Tanaka A, Nakajima N 2005
The design, synthesis and biological evaluations of C-6 or C-7 substituted 2-hydroxyisoquinoline-1,3-diones as inhibitors of hepatitis C virus. Chen YL, Tang J, Kesler MJ, Sham YY, Vince R, Geraghty RJ, Wang Z 2011
Lucidenic acid O and lactone, new terpene inhibitors of eukaryotic DNA polymerases from a basidiomycete, Ganoderma lucidum. Mizushina Y, Takahashi N, Hanashima L, Koshino H, Esumi Y, Uzawa J, Sugawara F, Sakaguchi K 1999
Hybrid diarylbenzopyrimidine non-nucleoside reverse transcriptase inhibitors as promising new leads for improved anti-HIV-1 chemotherapy. Zeng ZS, He QQ, Liang YH, Feng XQ, Chen FE, De Clercq E, Balzarini J, Pannecouque C 2010
Design, synthesis, and structure-activity relationships of 1,3-dihydrobenzimidazol-2-one analogues as anti-HIV agents. Monforte AM, Logoteta P, Ferro S, De Luca L, Iraci N, Maga G, Clercq ED, Pannecouque C, Chimirri A 2009
Design, synthesis, anti-HIV evaluation and molecular modeling of piperidine-linked amino-triazine derivatives as potent non-nucleoside reverse transcriptase inhibitors. Chen X, Zhan P, Liu X, Cheng Z, Meng C, Shao S, Pannecouque C, De Clercq E, Liu X 2012
Enzymatic synthesis of perfluoroalkylated DNA. Holzberger B, Marx A 2009
Novel N1-substituted 1,3-dihydro-2H-benzimidazol-2-ones as potent non-nucleoside reverse transcriptase inhibitors. Monforte AM, Rao A, Logoteta P, Ferro S, De Luca L, Barreca ML, Iraci N, Maga G, De Clercq E, Pannecouque C, Chimirri A 2008
Pharmacophore and structure-activity relationships of integrase inhibition within a dual inhibitor scaffold of HIV reverse transcriptase and integrase. Wang Z, Tang J, Salomon CE, Dreis CD, Vince R 2010
1-deoxyrubralactone, a novel specific inhibitor of families X and Y of eukaryotic DNA polymerases from a fungal strain derived from sea algae. Naganuma M, Nishida M, Kuramochi K, Sugawara F, Yoshida H, Mizushina Y 2008
Inhibitory effect of novel 5-O-acyl juglones on mammalian DNA polymerase activity, cancer cell growth and inflammatory response. Maruo S, Kuriyama I, Kuramochi K, Tsubaki K, Yoshida H, Mizushina Y 2011
Structure-activity relationships of epolactaene analogs as DNA polymerases inhibitors. Kuramochi K, Mizushina Y, Nagata S, Sugawara F, Sakaguchi K, Kobayashi S 2004
Penicilliols A and B, novel inhibitors specific to mammalian Y-family DNA polymerases. Kimura T, Takeuchi T, Kumamoto-Yonezawa Y, Ohashi E, Ohmori H, Masutani C, Hanaoka F, Sugawara F, Yoshida H, Mizushina Y 2009
Novel azaphilones, kasanosins A and B, which are specific inhibitors of eukaryotic DNA polymerases beta and lambda from Talaromyces sp. Kimura T, Nishida M, Kuramochi K, Sugawara F, Yoshida H, Mizushina Y 2008
Novel 1,3-dihydro-benzimidazol-2-ones and their analogues as potent non-nucleoside HIV-1 reverse transcriptase inhibitors. Monforte AM, Logoteta P, De Luca L, Iraci N, Ferro S, Maga G, De Clercq E, Pannecouque C, Chimirri A 2010
5-Alkyl-2-alkylamino-6-(2,6-difluorophenylalkyl)-3,4-dihydropyrimidin-4(3H)-ones, a new series of potent, broad-spectrum non-nucleoside reverse transcriptase inhibitors belonging to the DABO family. Mai A, Artico M, Ragno R, Sbardella G, Massa S, Musiu C, Mura M, Marturana F, Cadeddu A, Maga G, La Colla P 2005
Design and synthesis of dual inhibitors of HIV reverse transcriptase and integrase: introducing a diketoacid functionality into delavirdine. Wang Z, Vince R 2008
Synthesis and biological evaluation of 4-(hydroxyimino)arylmethyl diarylpyrimidine analogues as potential non-nucleoside reverse transcriptase inhibitors against HIV. Feng XQ, Zeng ZS, Liang YH, Chen FE, Pannecouque C, Balzarini J, De Clercq E 2010
Inhibitory effect of novel somatostatin peptide analogues on human cancer cell growth based on the selective inhibition of DNA polymerase β Kuriyama I, Miyazaki A, Tsuda Y, Yoshida H, Mizushina Y 2012
Bisphosphonate inhibitors of ATP-mediated HIV-1 reverse transcriptase catalyzed excision of chain-terminating 3'-azido, 3'-deoxythymidine: a QSAR investigation. Song Y, Chan JM, Tovian Z, Secrest A, Nagy E, Krysiak K, Bergan K, Parniak MA, Oldfield E 2008
Synthesis and anti-HIV evaluation of novel 1,3-disubstituted thieno[3,2-c][1,2,6]thiadiazin-4(3H)-one 2,2-dioxides(TTDDs). Lin Y, Liu X, Yan R, Li J, Pannecouque C, Witvrouw M, De Clercq E 2008
1-[2-(2-Benzoyl- and 2-benzylphenoxy)ethyl]uracils as potent anti-HIV-1 agents. Novikov MS, Ivanova ON, Ivanov AV, Ozerov AA, Valuev-Elliston VT, Temburnikar K, Gurskaya GV, Kochetkov SN, Pannecouque C, Balzarini J, Seley-Radtke KL 2011
Synthesis and biological evaluation of novel 6-substituted 5-alkyl-2-(arylcarbonylmethylthio)pyrimidin-4(3H)-ones as potent non-nucleoside HIV-1 reverse transcriptase inhibitors. Wang YP, Chen FE, De Clercq E, Balzarini J, Pannecouque C 2008
Synthesis and evaluation of 2-(2,6-dihalophenyl)-3-pyrimidinyl-1,3-thiazolidin-4-one analogues as anti-HIV-1 agents. Rawal RK, Tripathi R, Katti SB, Pannecouque C, De Clercq E 2007
Synthesis and anti-HIV activity of cosalane analogues incorporating nitrogen in the linker chain. Casimiro-Garcia A, De Clercq E, Pannecouque C, Witvrouw M, Stup TL, Turpin JA, Buckheit RW, Cushman M 2000
Synthesis and biological evaluation of imidazole thioacetanilides as novel non-nucleoside HIV-1 reverse transcriptase inhibitors. Zhan P, Liu X, Zhu J, Fang Z, Li Z, Pannecouque C, Clercq ED 2009
Synthesis and anti-HIV activity of 2-naphthyl substituted DAPY analogues as non-nucleoside reverse transcriptase inhibitors. Liang YH, He QQ, Zeng ZS, Liu ZQ, Feng XQ, Chen FE, Balzarini J, Pannecouque C, Clercq ED 2010
Synthesis and anti-HIV activity of 1,1,3-trioxo-2H,4H-thieno[3,4-e][1,2,4]thiadiazines (TTDs): a new family of HIV-1 specific non-nucleoside reverse transcriptase inhibitors. Arranz ME, Díaz JA, Ingate ST, Witvrouw M, Pannecouque C, Balzarini J, De Clercq E, Vega S 1999
Synthesis and biological evaluation of novel 5-alkyl-2-arylthio-6-((3,4-dihydroquinolin-1(2H)-yl)methyl)pyrimidin-4(3H)-ones as potent non-nucleoside HIV-1 reverse transcriptase inhibitors. Zhang J, Zhan P, Wu J, Li Z, Jiang Y, Ge W, Pannecouque C, De Clercq E, Liu X 2011
1,2,3-Selenadiazole thioacetanilides: synthesis and anti-HIV activity evaluation. Zhan P, Liu X, Fang Z, Pannecouque C, De Clercq E 2009
Synthesis and anti-HIV activity of new alkenyldiarylmethane (ADAM) non-nucleoside reverse transcriptase inhibitors (NNRTIs) incorporating benzoxazolone and benzisoxazole rings. Deng BL, Cullen MD, Zhou Z, Hartman TL, Buckheit RW, Pannecouque C, De Clercq E, Fanwick PE, Cushman M 2006
Discovery of novel 2-(3-(2-chlorophenyl)pyrazin-2-ylthio)-N-arylacetamides as potent HIV-1 inhibitors using a structure-based bioisosterism approach. Zhan P, Chen W, Li Z, Li X, Chen X, Tian Y, Pannecouque C, Clercq ED, Liu X 2012
N(1),N(3)-disubstituted uracils as nonnucleoside inhibitors of HIV-1 reverse transcriptase. Novikov MS, Valuev-Elliston VT, Babkov DA, Paramonova MP, Ivanov AV, Gavryushov SA, Khandazhinskaya AL, Kochetkov SN, Pannecouque C, Andrei G, Snoeck R, Balzarini J, Seley-Radtke KL 2013
Synthesis and biological evaluation of pyridazine derivatives as novel HIV-1 NNRTIs. Li D, Zhan P, Liu H, Pannecouque C, Balzarini J, De Clercq E, Liu X 2013
Improving bioorthogonal protein ubiquitylation by click reaction. Schneider D, Schneider T, Rösner D, Scheffner M, Marx A 2013
Towards new C6-rigid S-DABO HIV-1 reverse transcriptase inhibitors: Synthesis, biological investigation and molecular modeling studies. Wu HQ, Yan ZH, Chen WX, He QQ, Chen FE, De Clercq E, Balzarini J, Daelemans D, Pannecouque C 2013

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