Mouse pol alpha

From Mus musculus (aliases:Mmu pol alpha)
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Welcome to the Polymerase Page

This page presents all the information in Polbase for Mouse pol alpha.

Mutants:

At the top of the page you'll find a map of all positions of known mutants. Text links to mutants and digestion products are listed in the Mutants section.

Structures/Sequence:

If available, a representative structure is displayed at the upper right. All known structures are listed in the Structures section.

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References:

All references that refer to this Polymerase are listed with their topics and paper's title in the References table.

Results:

All the results for this polymerase can be examined by following the "Results" link at the bottom of the page.

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Mouse pol alpha is a family B enzyme from Mus musculus.

Selected Properties for Mouse pol alpha:

 3'-5' exo activity 5'-3' exo activity Frameshift Rate Substitution Rate General Error Rate
no data no data no data no data no data
Year Authors Title Results by property
2009 Christian S Eichinger, Takeshi Mizuno, Keiko Mizuno, Yasuyuki Miyake, Ken-ichiro Yanagi, Naoko Imamoto, Fumio Hanaoka Aberrant DNA polymerase alpha is excl...
1999 Takeshi Mizuno, K Yamagishi, Hiroshi Miyazawa, Fumio Hanaoka Molecular architecture of the mouse D...
1998 Takeshi Mizuno, Nobutoshi Ito, Masayuki Yokoi, Atsushi Kobayashi, Katsuyuki Tamai, Hiroshi Miyazawa, Fumio Hanaoka The second-largest subunit of the mou...

Predicted Structure Model

Predicted model AlphaFold DB Not experimentally determined

This AlphaFold DB model is predicted and not an experimentally determined structure. View AlphaFold DB entry Download predicted model (.pdb)

Confidence legend (pLDDT)

AlphaFold DB colors residues by predicted confidence. Use high-confidence regions for structural context and treat low-confidence regions cautiously.

  • Very high (pLDDT > 90) Backbone and side chains are usually reliable.
  • Confident (pLDDT 70-90) Overall fold is usually reliable, but some local detail may shift.
  • Low (pLDDT 50-70) Use with caution; this region may be flexible or uncertain.
  • Very low (pLDDT < 50) Often disordered or not confidently placed.

Version:20260603

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