KF D424A

From E. coli
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Mutant of: Klenow fragment (D424A)

KF D424A is a family A enzyme from E. coli.

Selected Properties for KF D424A:

3'-5' exo activity 5'-3' exo activity Frameshift Rate Substitution Rate General Error Rate
No (2) no data 5.0e-06-4.3e-03 errors/bp (2) 2.5e-05-1.2e-04 errors/bp (2) no data
Year Authors Title Results by property
2007 Gudrun Stengel, JP Gill, Peter Sandin, L Marcus Wilhelmsson, Bo Albinsson, Bengt Nordén, David P Millar Conformational dynamics of DNA polyme...
1991 V Derbyshire, Nigel D F Grindley, Catherine M Joyce The 3'-5' exonuclease of DNA polymera... Specific Activity,kcat,All properties
1991 Lorena S Beese, Thomas A Steitz Structural basis for the 3'-5' exonuc...
1990 Katarzyna Bebenek, Catherine M Joyce, M P Fitzgerald, Thomas A Kunkel The fidelity of DNA synthesis catalyz... 3-5' exo,Frameshift Error Rate,Nucleotide Substitution Rate,All properties
1988 V Derbyshire, P S Freemont, M R Sanderson, L Beese, J M Friedman, Catherine M Joyce, Thomas A Steitz Genetic and crystallographic studies ... Specific Activity,Other Important Residues,All properties