KF D424A

From E. coli
show help

Welcome to the Polymerase Page

This page presents all the information in Polbase for KF D424A.

Mutants:

At the top of the page you'll find a map of all positions of known mutants. Text links to mutants and digestion products are listed in the Mutants section.

Structures/Sequence:

If available, a representative structure is displayed at the upper right. All known structures are listed in the Structures section.

External links:

Polbase polymerases are linked to UniProt and Genbank where possible. The UniProt search link directs you to a pre-constructed UniProt search containing relevant terms.

References:

All references that refer to this Polymerase are listed with their topics and paper's title in the References table.

Results:

All the results for this polymerase can be examined by following the "Results" link at the bottom of the page.

Help icons:

The show help symbol in the upper-right corner of the page links to this help text. The question mark icon is used everywhere to indicate that help is available.

Mutant of: Klenow fragment (D424A)

KF D424A is a family A enzyme from E. coli.

Selected Properties for KF D424A:

3'-5' exo activity 5'-3' exo activity Frameshift Rate Substitution Rate General Error Rate
No (2) no data 5.0e-06-4.3e-03 errors/bp (2) 2.5e-05-1.2e-04 errors/bp (2) no data
Year Authors Title Results by property
2007 Gudrun Stengel, JP Gill, Peter Sandin, L Marcus Wilhelmsson, Bo Albinsson, Bengt Nordén, David P Millar Stengel G2007
1991 V Derbyshire, Nigel D F Grindley, Catherine M Joyce Derbyshire V1991 Specific Activity,kcat,All properties
1991 Lorena S Beese, Thomas A Steitz Beese LS1991
1990 Katarzyna Bebenek, Catherine M Joyce, M P Fitzgerald, Thomas A Kunkel Bebenek K1990 3-5' exo,Frameshift Error Rate,Nucleotide Substitution Rate,All properties
1988 V Derbyshire, P S Freemont, M R Sanderson, L Beese, J M Friedman, Catherine M Joyce, Thomas A Steitz Derbyshire V1988 Specific Activity,Other Important Residues,All properties
All Polymerases | 11 Results

Using Polbase tables:

Sorting:

Tables may be sorted by clicking on any of the column titles. A second click reverses the sort order. <Ctrl> + click on the column titles to sort by more than one column (e.g. family then name).

Filtering:

It is also possible to filter the table by typing into the search box above the table. This will instantly hide lines from the table that do not contain your search text.