Spectrum of spontaneous frameshift mutations. Sequences of bacteriophage T4 rII gene frameshifts.

Abstract:

The DNA sequences of 185 independent spontaneous frameshift mutations ...

Polymerases:

T4

Topics:

Fidelity

One line summary:

The spectrum of frameshift mutations generated in the rIIB gene in vivo by the wild type T4 DNA polymerase suggest a role for complex mutations in evolution.

Status:

new topics/pols set partial results complete validated

Results:

Polymerase Reference Property Result Context
T4 Spectrum of spontaneous frameshift mutations. Sequences of bacteriophage T4 rII gene frameshifts. Frameshift Error Rate 3E-07 errors/bp

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