Error-prone DNA polymerases: novel structures and the benefits of infidelity.
Abstract:
Studies on several recently discovered error-prone DNA polymerases reveal novel structures that may explain the low fidelity of this general class of enzymes, a number of which are involved in the replicative bypass (translesion synthesis) of base damage in DNA.
Polymerases:
Topics:
Structure and Structure/Function
Note:
The review is largely based on the crystal structure of Dpo4.
Status:
new | topics/pols set | partial results | complete | validated |
Results:
No results available for this paper.