Development of a new DNA sequencing method: 3'-ester cleavage catalyzed by Taq DNA polymerase.
Abstract:
A new 3'-esterified dTTP is incorporated into DNA by Taq DNA polymerase but does not act as a chain terminator. The esterase activity of the polymerase seems to be template dependent and occurs only if the next correct nucleotide is present.
Polymerases:
Topics:
Status:
new | topics/pols set | partial results | complete | validated |
Results:
No results available for this paper.