Taq pol I
From
Thermus aquaticus
(aliases:Taq)
Welcome to the Polymerase Page
This page presents all the information in Polbase for Taq pol I.
Mutants:At the top of the page you'll find a map of all positions of known mutants. Text links to mutants and digestion products are listed in the Mutants section.
Structures/Sequence:If available, a representative structure is displayed at the upper right. All known structures are listed in the Structures section.
External links:Polbase polymerases are linked to UniProt and Genbank where possible. The UniProt search link directs you to a pre-constructed UniProt search containing relevant terms.
References:All references that refer to this Polymerase are listed with their topics and paper's title in the References table.
Results:All the results for this polymerase can be examined by following the "Results" link at the bottom of the page.
Help icons:
The symbol in the upper-right corner of the page
links to this help text. The question mark icon is used everywhere to indicate that help is available.
Taq pol I
is a family A enzyme
from
Thermus aquaticus.
Selected Properties for Taq pol I: |
3'-5' exo activity | 5'-3' exo activity | Frameshift Rate | Substitution Rate | General Error Rate |
|---|---|---|---|---|---|
| No (8) | Yes (5) | 4.8e-06-5.3e-05 errors/bp (3) | 3.3e-06-1.9e-03 errors/bp (9) | 8.0e-06-2.0e-04 errors/bp (7) |
- References (179)
- Structures (8)
- Sequences (1)
- Mutants (19)...
- Formulations (46)
- Polymerase Lots (0)
- External links
| Year | Authors | Title | Results by property |
|---|---|---|---|
| 2014 | Chin-Chi Liu, Vince J LiCata | The stability of Taq DNA polymerase r... | |
| 2013 | Samra Obeid, H Bußkamp, Wolfram Welte, Kay Diederichs, Andreas Marx | Snapshot of a DNA polymerase while in... | |
| 2013 | Gumjung Lim, Joungmok Kim, Jeong Hee Kim | Optimization of the masking molecule ... | |
| 2013 | Brian J Keith, Stanislaw K Jozwiakowski, Bernard A Connolly | A plasmid-based lacZα gene assay for ... | Overall Error Rate,All properties |
| 2012 | Tian-Lei Liu, Shou-Bin Xue, Fang Wang, Lin-Ying Zhu, Wei-Wei Liang, Sheng-Xuan Qu, Wen-Bo Cai | [Purification of Taq DNA polymerase e... | |
| 2012 | Praveen Nedumpully Govindan, Luca Monticelli, Emppu Salonen | Mechanism of taq DNA polymerase inhib... | |
| 2012 | Daniela Bessa, Filipa Pereira, Roxana Moreira, Björn Johansson, Odília Queirós | Improved gap repair cloning in yeast:... | |
| 2012 | Xiaoqing Yu, Xiaoqi Zheng, Liangyu Meng, Chun Li, Jun Wang | A Support Vector Machine Based Method... | |
| 2012 | Carlos Rodolfo Pungitore, Celina García, V Sotero Martín, Carlos E Tonn | Inhibition of Taq DNA polymerase by i... | |
| 2011 | Ping Xie, Jon R Sayers | A model for transition of 5'-nuclease... | |
| 2011 | Osvaldo A Martin, Hugo A Garro, Marcela B Kurina Sanz, Carlos Rodolfo Pungitore, Carlos E Tonn | In silico study of the inhibition of ... | |
| 2011 | Gumjung Lim, Hyun Jin Hwang, Jeong Hee Kim | Protected immobilization of Taq DNA p... | |
| 2011 | H Niimi, M Mori, H Tabata, H Minami, Takayuki Ueno, S Hayashi, I Kitajima | A novel "eukaryote-made" thermostable... | |
| 2011 | Samra Obeid, Andreas Schnur, Christian Gloeckner, Nina Blatter, Wolfram Welte, Kay Diederichs, Andreas Marx | Learning from Directed Evolution: The... | |
| 2010 | Sophie Vichier-Guerre, Jean-Luc Jestin | Characterisation of a DNA polymerase ... | |
| 2010 | Karin Betz, Frank Streckenbach, Andreas Schnur, Thomas Exner, Wolfram Welte, Kay Diederichs, Andreas Marx | Structures of DNA polymerases caught ... | |
| 2010 | Dad D Roux-Michollet, Joshua P Schimel, Patricia A Holden | Pushing the limits for amplifying Brd... | |
| 2010 | Wujie Li, Mou Cao, Lu Pei, Xiaomei Ling, Bingchao Li, Zhenjun Yang | Study on steady-state kinetics of nuc... | |
| 2010 | Guojie Zhao, Yifu Guan | Polymerization behavior of Klenow fra... | |
| 2010 | Samra Obeid, Anna Baccaro, Wolfram Welte, Kay Diederichs, Andreas Marx | Structural basis for the synthesis of... | |
| 2010 | Ramon Kranaster, Matthias Drum, Nicole Engel, Manfred Weidmann, Frank T Hufert, Andreas Marx | One-step RNA pathogen detection with ... | |
| 2009 | Qiuying Huang, Qingge Li | Characterization of the 5' to 3' nucl... | 3-5' exo,5-3' exo,All properties |
| 2009 | Md Monsur Ali, Shuhei Imoto, Yingqian Li, Shigeki Sasaki, Fumi Nagatsugi | Incorporation of an inducible nucleot... | |
| 2009 | Thomas E Exner | Insights into the high fidelity of a ... | |
| 2009 | Younguk Sun, Kalvin J Gregory, Val Golovlev | Efficiency and specificity of microRN... | |
| 2009 | Suk-Tae Kwon, Hyekyung Shim, Jin Choia Jeong, Jae Kima Yun, Jae-Geun Songa, Eui-Joon Kila, Il Lee Jong | Characterization and PCR optimization... | Vmax,Overall Error Rate,All properties |
| 2009 | Lijiang Wang, Qingjun Liu, Zhaoying Hu, Yongqing Zhang, Chunsheng Wu, Mo Yang, Ping Wang | A novel electrochemical biosensor bas... | |
| 2009 | Milko B Kermekchiev, Lyubka I Kirilova, Erika E Vail, Wayne M Barnes | Mutants of Taq DNA polymerase resista... | |
| 2009 | J W Brandis, Kenneth A Johnson | High-cell density shake-flask express... | |
| 2008 | Zhengan Yang, Yumei Ding, Yongqing Zhang, Feihu Liu | Rapid purification of truncated Taq D... | |
| 2008 | J Gury, L Zinger, L Gielly, P Taberlet, RA Geremia | Exonuclease activity of proofreading ... | |
| 2008 | Linda J Reha-Krantz | Recent patents of gene sequences rela... | |
| 2008 | Hyung Joo Jin, Mi Young Oh, Deuk Hee Jin, Yong Ki Hong | Identification of a Taq DNA polymeras... | |
| 2007 | Marc d'Abbadie, Michael Hofreiter, Alexandra Vaisman, David Loakes, Didier Gasparutto, Jean Cadet, Roger Woodgate, Svante Pääbo, Philipp Holliger | Molecular breeding of polymerases for... | |
| 2007 | Hayan Lee, Kyung-Nam Kim, Young Kee Chae | Reevaluating the capability of Taq DN... | |
| 2007 | Jan A Sikorsky, Donald A Primerano, Terry W Fenger, James Denvir | DNA damage reduces Taq DNA polymerase... | |
| 2007 | Michael Strerath, Christian Gloeckner, Dan Liu, Andreas Schnur, Andreas Marx | Directed DNA polymerase evolution: ef... | |
| 2007 | Huseyin Avni Oktem, Gulay Bayramoglu, V Cengiz Ozalp, M Yakup Arica | Single-step purification of recombina... | |
| 2007 | Sotirios Melissis, Nikolaos E Labrou, Yannis D Clonis | One-step purification of Taq DNA poly... | |
| 2007 | Carlos Rodolfo Pungitore, Leticia G León, Celina García, Víctor S Martín, Carlos E Tonn, José M Padrón | Novel antiproliferative analogs of th... | |
| 2006 | Jae Seok Song, Jung Hun Lee, Jung-Hyun Lee, Byeong Chul Jeong, Won-Keun Lee, Sang Hee Lee | Removal of contaminating TEM-la beta-... | |
| 2006 | Huayou Chen, Zhongmei Chu, Yongqing Zhang, Shengli Yang | Over-expression and characterization ... | |
| 2006 | John P McDonald, Ashley Hall, Didier Gasparutto, Jean Cadet, Jack Ballantyne, Roger Woodgate | Novel thermostable Y-family polymeras... | |
| 2006 | Pongpan Laksanalamai, Andrey R Pavlov, Alexei I Slesarev, Frank T Robb | Stabilization of Taq DNA polymerase a... | |
| 2006 | Takahisa Noma, Koji Sode, Kazunori Ikebukuro | Characterization and application of a... | |
| 2005 | Jon P Anderson, Bernhard Angerer, Lawrence A Loeb | Incorporation of reporter-labeled nuc... | Cloned or native,Tagged,Full length or truncated,3-5' exo,5-3' exo,Application name,Incorporation of non-standard nucleotides,All properties |
| 2005 | Atsushi Kobayashi, Motomitsu Kitaoka, Kiyoshi Hayashi | Novel PCR-mediated mutagenesis employ... | |
| 2005 | Young Shik Chi, Young Hwan Jung, Insung S Choi, Yang-Gyun Kim | Surface-initiated growth of poly d(A-... | |
| 2005 | François Vigneault, Régen Drouin | Optimal conditions and specific chara... | |
| 2004 | Farid J Ghadessy, Nicola Ramsay, François Boudsocq, David Loakes, Anthony Brown, Shigenori Iwai, Alexandra Vaisman, Roger Woodgate, Philipp Holliger | Generic expansion of the substrate sp... | |
| 2004 | Nancy Quach, Myron F Goodman, Darryl Shibata | In vitro mutation artifacts after for... | |
| 2004 | Allyn J Schoeffler, Allison M Joubert, Fenggang Peng, Farheen Khan, Chin-Chi Liu, Vince J LiCata | Extreme free energy of stabilization ... | |
| 2004 | Carlos Rodolfo Pungitore, M Juri Ayub, Eduardo J Borkowski, Carlos E Tonn, G M Ciuffo | Inhibition of Taq DNA polymerase by c... | |
| 2003 | Kausiki Datta, Vince J LiCata | Thermodynamics of the binding of Ther... | |
| 2003 | Kazunori Ikebukuro, Takahisa Noma | Screening of DNA aptamers inhibiting ... | |
| 2003 | Linda M Benson, Allison P Null, David C Muddiman | Advantages of Thermococcus kodakaraen... | |
| 2003 | O Yu Yakimovich, Ya I Alekseev, A V Maksimenko, O L Voronina, V G Lunin | Influence of DNA aptamer structure on... | |
| 2003 | N R Isola, Z Liu, S L Allman, N I Taranenko, Y Kong, C H Chen | Matrix-assisted laser desorption/ioni... | |
| 2003 | Jim Youngblom | Extended stability of Taq DNA polymer... | |
| 2003 | Deepali Shinde, Yinglei Lai, Fengzhu Sun, Norman Arnheim | Taq DNA polymerase slippage mutation ... | |
| 2003 | Milko B Kermekchiev, Anatoly Tzekov, Wayne M Barnes | Cold-sensitive mutants of Taq DNA pol... | Nucleotide Substitution Rate,All properties |
| 2003 | Natasha Paul, Vishal C Nashine, Geoffrey Hoops, Peiming Zhang, Jie Zhou, Donald E Bergstrom, V Jo Davisson | DNA polymerase template interactions ... | |
| 2003 | John F Davidson, Richard Fox, Dawn D Harris, Sally Lyons-Abbott, Lawrence A Loeb | Insertion of the T3 DNA polymerase th... | Specific Activity,Processivity,5-3' exo,Nucleotide Substitution Rate,All properties |
| 2002 | Andrew F Gardner, William E Jack | Acyclic and dideoxy terminator prefer... | |
| 2002 | Gang Xia, Liangjing Chen, Takashi Sera, Ming Fa, Peter G Schultz, Floyd E Romesberg | Directed evolution of novel polymeras... | |
| 2002 | Tadayuki Imanaka, Haruyuki Atomi | Catalyzing "hot" reactions: enzymes f... | |
| 2001 | Jochen Wilhelm, Alfred Pingoud, Meinhard Hahn | Comparison between Taq DNA polymerase... | |
| 2001 | Enrique Viguera, D Canceill, S Dusko Ehrlich | In vitro replication slippage by DNA ... | |
| 2001 | Yingqian Li, Gabriel Waksman | Crystal structures of a ddATP-, ddTTP... | |
| 2001 | Masanori Ogawa, A Tosaka, Yasutomo Ito, Shonen Yoshida, Motoshi Suzuki | Enhanced ribonucleotide incorporation... | |
| 2001 | A Tosaka, Masanori Ogawa, Shonen Yoshida, Motoshi Suzuki | O-helix mutant T664P of Thermus aquat... | |
| 2001 | Holly H Hogrefe, J Cline, A E Lovejoy, K B Nielson | DNA polymerases from hyperthermophiles. | RT,Specific Activity,Processivity,Strand Displacement,3-5' exo,5-3' exo,KM,kcat,Overall Error Rate,All properties |
| 2001 | K Yoshida, A Tosaka, Hiroyuki Kamiya, Takashi Murate, Hironori Kasai, Y Nimura, Masanori Ogawa, Shonen Yoshida, Motoshi Suzuki | Arg660Ser mutation in Thermus aquatic... | |
| 2001 | Farid J Ghadessy, J L Ong, Philipp Holliger | Directed evolution of polymerase func... | |
| 2000 | B Villbrandt, H Sobek, B Frey, D Schomburg | Domain exchange: chimeras of Thermus ... | |
| 2000 | P H Patel, Lawrence A Loeb | DNA polymerase active site is highly ... | |
| 2000 | Motoshi Suzuki, Shonen Yoshida, Elinor T Adman, A Blank, Lawrence A Loeb | Thermus aquaticus DNA polymerase I mu... | |
| 2000 | P H Patel, Lawrence A Loeb | Multiple amino acid substitutions all... | |
| 2000 | Y P Zhang, A Rowhani | A strategy for rapid cDNA cloning fro... | |
| 2000 | K Nord, E Gunneriusson, M Uhlén, P A Nygren | Ligands selected from combinatorial l... | |
| 1999 | Yingqian Li, V Mitaxov, Gabriel Waksman | Structure-based design of Taq DNA pol... | |
| 1999 | K B Ignatov, A A Bashirova, A I Miroshnikov, V M Kramarov | Mutation S543N in the thumb subdomain... | |
| 1999 | Bruno Canard, Kajal Chowdhury, R Sarfati, Sylvie Doublié, Charles C Richardson | The motif D loop of human immunodefic... | |
| 1999 | B Baury, D Masson, P Lustenberger, M G Denis | Gene walking by PCR amplification of ... | |
| 1999 | Jun Zhang, C N Ji, H S Du, Z H Zheng, Y M Mao | [A study of a derivative of Taq DNA p... | |
| 1999 | U K Urs, R Murali, H M Krishna Murthy | Structure of taq DNA polymerase shows... | |
| 1999 | Thomas A Steitz | DNA polymerases: structural diversity... | |
| 1999 | J W Brandis | Dye structure affects Taq DNA polymer... | |
| 1999 | Sylvie Doublié, M R Sawaya, Tom Ellenberger | An open and closed case for all polym... | |
| 1999 | V Lyamichev, M A Brow, V E Varvel, J E Dahlberg | Comparison of the 5' nuclease activit... | |
| 1999 | I Rasolonjatovo, S R Sarfati | Development of a new DNA sequencing m... | |
| 1999 | R A Reiss, B Rutz | Quality control PCR: a method for det... | |
| 1999 | E Gunneriusson, K Nord, M Uhlén, P Nygren | Affinity maturation of a Taq DNA poly... | |
| 1998 | R Murali, M Helmer-Citterich, D J Sharkey, E R Scalice, J L Daiss, M A Sullivan, H M Krishna Murthy | Structural studies on an inhibitory a... | |
| 1998 | S K Poddar, M H Sawyer, J D Connor | Effect of inhibitors in clinical spec... | |
| 1998 | P G Zaphiropoulos | Non-homologous recombination mediated... | |
| 1998 | K B Ignatov, A I Miroshnikov, V M Kramarov | Substitution of Asn for Ser543 in the... | |
| 1998 | K Hanaki, T Odawara, Noriyuki Nakajima, Y K Shimizu, C Nozaki, K Mizuno, T Muramatsu, Y Kuchino, H Yoshikura | Two different reactions involved in t... | |
| 1998 | H J Huang, C Pears | Generation of genomic mini-libraries ... | |
| 1998 | C Kebelmann-Betzing, K Seeger, S Dragon, G Schmitt, A Möricke, T A Schild, G Henze, B Beyermann | Advantages of a new Taq DNA polymeras... | |
| 1998 | Yoshiyuki Mizushina, T Ueno, Y Goto, Y Isobe, M Sako, T Fujita, Kouji Hirota, H Hayashi, Kengo Sakaguchi | Carboxyflavins, novel inhibitors of T... | |
| 1998 | Yingqian Li, S Korolev, Gabriel Waksman | Crystal structures of open and closed... | |
| 1998 | Yingqian Li, Y Kong, S Korolev, Gabriel Waksman | Crystal structures of the Klenow frag... | |
| 1998 | R Murali, D J Sharkey, J L Daiss, H M Murthy | Crystal structure of Taq DNA polymera... | |
| 1998 | James R Kiefer, C Mao, J C Braman, Lorena S Beese | Visualizing DNA replication in a cata... | Full length or truncated,Specific Activity,Processivity,3-5' exo,KM,kcat,All properties |
| 1998 | D F Chen, I Seibert, H Y Chen, I Herbst-Kiene, L T Pastucha, W Stangel | Improvement of HLA class I and class ... | |
| 1997 | B Villbrandt, G Sagner, D Schomburg | Investigations on the thermostability... | |
| 1997 | Y Park, H Choi, D S Lee, Y Kim | Improvement of the 3'-5' exonuclease ... | |
| 1997 | Y Kim, Joong Su Kim, Y Park, C S Chang, S W Suh, D S Lee | Mutagenesis of the positively charged... | |
| 1997 | L A Haff, I P Smirnov | Single-nucleotide polymorphism identi... | |
| 1997 | T Gräslund, J Nilsson, A M Lindberg, M Uhlén, P A Nygren | Production of a thermostable DNA poly... | |
| 1997 | James R Kiefer, C Mao, Connie J Hansen, S L Basehore, Holly H Hogrefe, J C Braman, Lorena S Beese | Crystal structure of a thermostable B... | Specific Activity,Processivity,KM,kcat,All properties |
| 1997 | J Fan, R S Ranu | Direct cycle sequencing with delta Ta... | |
| 1997 | C Leelayuwat, T Srisuk, R Paechaiyaphum, T Limpaiboon, A Romphruk, A Romphruk | Production and evaluation of Taq DNA ... | |
| 1997 | G C Hoops, Peiming Zhang, W T Johnson, Natasha Paul, Donald E Bergstrom, V Jo Davisson | Template directed incorporation of nu... | |
| 1997 | J Nilsson, M Bosnes, F Larsen, P A Nygren, M Uhlén, J Lundeberg | Heat-mediated activation of affinity-... | |
| 1997 | Zhixin Chen, D E Ruffner | Post-PCR labeling using Taq DNA polym... | |
| 1997 | D Yu, M Mukai, Q Liu, C R Steinman | Specific inhibition of PCR by non-ext... | |
| 1997 | Motoshi Suzuki, A K Avicola, L Hood, Lawrence A Loeb | Low fidelity mutants in the O-helix o... | |
| 1996 | Motoshi Suzuki, D Baskin, L Hood, Lawrence A Loeb | Random mutagenesis of Thermus aquatic... | |
| 1996 | R E Wellinger, F Thoma | Taq DNA polymerase blockage at pyrimi... | |
| 1996 | C Dang, S D Jayasena | Oligonucleotide inhibitors of Taq DNA... | |
| 1996 | V I Grabko, L G Chistyakova, V N Lyapustin, V G Korobko, A I Miroshnikov | Reverse transcription, amplification ... | |
| 1996 | J Cline, J C Braman, Holly H Hogrefe | PCR fidelity of pfu DNA polymerase an... | Overall Error Rate,All properties |
| 1996 | Xu Zhao, Jinming Li, Rong Li, Shuren Zhang, Yong Zhang, Zhengan Yang | Amplification, cloning, and sequence ... | |
| 1996 | J W Brandis, S G Edwards, Kenneth A Johnson | Slow rate of phosphodiester bond form... | |
| 1996 | F B Perler, Sandeep Kumar, H Kong | Thermostable DNA polymerases. | 3-5' exo,5-3' exo,Molecular Weight,All properties |
| 1996 | I Vainshtein, A Atrazhev, Soo Hyun Eom, J F Elliott, D S Wishart, B A Malcolm | Peptide rescue of an N-terminal trunc... | |
| 1996 | Soo Hyun Eom, Jianhong Wang, Thomas A Steitz | Structure of Taq polymerase with DNA ... | |
| 1995 | P C Loewen, J Switala | Template secondary structure can incr... | |
| 1995 | Y Kim, Soo Hyun Eom, Jianhong Wang, D S Lee, S W Suh, Thomas A Steitz | Crystal structure of Thermus aquaticu... | |
| 1995 | A De Milito, M Catucci, F Iannelli, L Romano, M Zazzi, P E Valensin | Increased reliability of selective PC... | |
| 1995 | U K Urs, D J Sharkey, T S Peat, W A Hendrickson, K Murthy | Characterization of crystals of the t... | |
| 1995 | R S Ranu | DNA sequencing with delta Taq DNA pol... | |
| 1995 | J R Smith, J D Carpten, M J Brownstein, Sharmistha Ghosh, V L Magnuson, D A Gilbert, J M Trent, F S Collins | Approach to genotyping errors caused ... | |
| 1995 | S J Odelberg, R B Weiss, A Hata, R White | Template-switching during DNA synthes... | |
| 1995 | Stanley Tabor, Charles C Richardson | A single residue in DNA polymerases o... | |
| 1995 | P N Hengen | Fidelity of DNA polymerases for PCR. | |
| 1995 | S Korolev, M Nayal, Wayne M Barnes, E Di Cera, Gabriel Waksman | Crystal structure of the large fragme... | |
| 1995 | L S Merkens, S K Bryan, Robb E Moses | Inactivation of the 5'-3' exonuclease... | |
| 1995 | U J Desai, P K Pfaffle | Single-step purification of a thermos... | |
| 1994 | Wayne M Barnes | PCR amplification of up to 35-kb DNA ... | |
| 1994 | Yoshizumi Ishino, Takayuki Ueno, M Miyagi, Takashi Uemori, M Imamura, S Tsunasawa, Ikunoshin Kato | Overproduction of Thermus aquaticus D... | |
| 1994 | M Wada, C Klein, J Schell, B Reiss | A functional assay for Taq DNA polyme... | |
| 1994 | D E Kellogg, I Rybalkin, S Chen, N Mukhamedova, T Vlasik, P D Siebert, A Chenchik | TaqStart Antibody: "hot start" PCR fa... | |
| 1994 | M S Hughes, L A Beck, R A Skuce | Identification and elimination of DNA... | |
| 1993 | H Kong, R B Kucera, William E Jack | Characterization of a DNA polymerase ... | Full length or truncated,Processivity,KM,All properties |
| 1993 | F G Pluthero | Rapid purification of high-activity T... | |
| 1993 | F C Lawyer, S Stoffel, R K Saiki, S Y Chang, P A Landre, R D Abramson, D H Gelfand | High-level expression, purification, ... | Cloned or native,Full length or truncated,Specific Activity,5-3' exo,Molecular Weight,Vmax,All properties |
| 1993 | Kristin A Eckert, Thomas A Kunkel | Fidelity of DNA synthesis catalyzed b... | |
| 1992 | Wayne M Barnes | The fidelity of Taq polymerase cataly... | |
| 1992 | P Hentosh, J C McCastlain, P Grippo, B Y Bugg | Polymerase chain reaction amplificati... | |
| 1992 | M M Huang, Norman Arnheim, Myron F Goodman | Extension of base mispairs by Taq DNA... | |
| 1992 | P A Garrity, B J Wold | Effects of different DNA polymerases ... | |
| 1992 | V Murray, H Motyka, P R England, G Wickham, H H Lee, W A Denny, W D McFadyen | The use of Taq DNA polymerase to dete... | |
| 1992 | L P Savochkina, L B Dĭachenko, M A Lukin, L A Aleksandrova | [Analogs of nucleotides, modified by ... | |
| 1992 | Q Chou | Minimizing deletion mutagenesis artif... | |
| 1991 | Y H Zhou, X P Zhang, R H Ebright | Random mutagenesis of gene-sized DNA ... | |
| 1991 | L L Ling, P Keohavong, C Dias, William G Thilly | Optimization of the polymerase chain ... | Overall Error Rate,All properties |
| 1991 | Kristin A Eckert, Thomas A Kunkel | DNA polymerase fidelity and the polym... | |
| 1991 | N F Cariello, James A Swenberg, T R Skopek | Fidelity of Thermococcus litoralis DN... | 3-5' exo,Nucleotide Substitution Rate,Application name,All properties |
| 1991 | N F Cariello, William G Thilly, James A Swenberg, T R Skopek | Deletion mutagenesis during polymeras... | |
| 1991 | M Ponti, S M Forrow, R L Souhami, M D'Incalci, J A Hartley | Measurement of the sequence specifici... | |
| 1991 | M J White, B W Fristensky, W F Thompson | Concatemer chain reaction: a Taq DNA ... | |
| 1991 | U Finckh, P A Lingenfelter, D Myerson | Producing single-stranded DNA probes ... | |
| 1990 | Kristin A Eckert, Thomas A Kunkel | High fidelity DNA synthesis by the Th... | Cloned or native,Full length or truncated,3-5' exo,Frameshift Error Rate,Nucleotide Substitution Rate,All properties |
| 1990 | D R Engelke, A Krikos, M E Bruck, D Ginsburg | Purification of Thermus aquaticus DNA... | |
| 1990 | Yoshizumi Ishino, Kiyozo Asada | [Methods of DNA sequencing with Taq D... | |
| 1989 | M M Becker, Zhengqiang Wang, G Grossmann, K A Becherer | Genomic footprinting in mammalian cel... | |
| 1989 | F C Lawyer, S Stoffel, R K Saiki, K Myambo, R Drummond, D H Gelfand | Isolation, characterization, and expr... | |
| 1989 | P Keohavong, William G Thilly | Fidelity of DNA polymerases in DNA am... | Nucleotide Substitution Rate,All properties |
| 1989 | H Kadowaki, T Kadowaki, F E Wondisford, S I Taylor | Use of polymerase chain reaction cata... | |
| 1989 | S Fucharoen, G Fucharoen, P Fucharoen, Y Fukumaki | A novel ochre mutation in the beta-th... | |
| 1988 | M A Innis, K B Myambo, D H Gelfand, M A Brow | DNA sequencing with Thermus aquaticus... | |
| 1988 | K R Tindall, Thomas A Kunkel | Fidelity of DNA synthesis by the Ther... | Full length or truncated,3-5' exo,Frameshift Error Rate,Nucleotide Substitution Rate,All properties |
| 1988 | R K Saiki, D H Gelfand, S Stoffel, S J Scharf, R Higuchi, G T Horn, K B Mullis, H A Erlich | Primer-directed enzymatic amplificati... | Nucleotide Substitution Rate,All properties |
| 1982 | Catherine M Joyce, W S Kelley, Nigel D F Grindley | Nucleotide sequence of the Escherichi... | Cloned or native,Tagged,Tag Name,Full length or truncated,All properties |
| 1980 | A S Kaledin, A G Sliusarenko, S I Gorodetskiĭ | [Isolation and properties of DNA poly... | |
| 1976 | A Chien, D B Edgar, J M Trela | Deoxyribonucleic acid polymerase from... |
Protein sequence:
Predicted Structure Model
Predicted model
AlphaFold DB
Not experimentally determined
This AlphaFold DB model is predicted and not an experimentally determined structure. View AlphaFold DB entry Download predicted model (.pdb)
Confidence legend (pLDDT)
AlphaFold DB colors residues by predicted confidence. Use high-confidence regions for structural context and treat low-confidence regions cautiously.
- Very high (pLDDT > 90) Backbone and side chains are usually reliable.
- Confident (pLDDT 70-90) Overall fold is usually reliable, but some local detail may shift.
- Low (pLDDT 50-70) Use with caution; this region may be flexible or uncertain.
- Very low (pLDDT < 50) Often disordered or not confidently placed.
| Name | 3'-5' exo activity | 5'-3' exo activity | Frameshift Rate | Substitution Rate | General Error Rate |
|---|---|---|---|---|---|
| Taq A608D | |||||
| Taq I614M | |||||
| Taq I614K | |||||
| Taq L614I | |||||
| Taq I614N | |||||
| Taq E615D | |||||
| Taq R660S | |||||
| Taq R660F | |||||
| Taq R660D | |||||
| Taq R660Y | |||||
| Taq R660L | |||||
| Taq (F667Y) | |||||
| Klentaq1 | 1.2e-04-1.5e-04 errors/bp (3) | ||||
| Taq (exo-) | No (1) | ||||
| Klentaq2 | |||||
| Stoffel fragment | No (1) | ||||
| TaqTBD (exo-) | |||||
| TaqTBD | Yes (1) | 1.5e-03 errors/bp (1) | |||
| Klentaq |
- AccuTaq LA DNA Polymerase
- AmpliTaq Gold® 360
- DF-Taq (NEB)
- Dream Taq DNA Polymerase
- FastStart High Fielity DNAP
- FastStart Taq DNAP
- GoTaq® Green Master Mix (2x)
- GoTaq Hot Start
- HotStar HiFielity Polymerase
- HotStarTaq
- Hot Start Taq 2X Master Mix
- Hot Start Taq lot 2
- JumpStart AccuTaq LA DNAP
- JumpStart Taq
- LA Taq Hot Start Version
- Maxima Hot Start Taq
- OneTaq 2X MM w GC Buffer M0483
- OneTaq GC MasterMix 20 (2X)
- OneTaq HotStart GC MasterMix 20 (2X)
- OneTaq HotStart MasterMix 21 (2X)
- OneTaq Hotstart Quickload 2X MM w/ GC Buffer
- OneTaq HotStart Quickload 2X MM w/ Standard Buffer
- OneTaq Hot StartTurboAmp Hot Start Prod lot
- OneTaq MasterMix 21 (2X)
- OneTaq Quickload 2X MM w/ GC Buffer
- OneTaq Quickload 2X MM w/ Standard Buffer
- OneTaqTurboAmp 25:1 prodn lot
- Platinum® Taq
- Quick-load Taq 2X Master Mix
- SP-45A*
- Taq 2Tip
- Taq 2Tip HsTaqDiluent
- Taq 2X Master Mix (NEB)
- Taq DSC 2.0 Hot Start DNA Polymerase
- Taq in house
- Taq lysate
- Taq (NEB)A
- Taq (NEB) with Thermopol Buffer (same protein as 4049P)
- Taq (NEB) w ST buffer (same protein as 1174P)
- TecRT3
- TecRT4
- Thermo-Start Taq DNAP
- TopTaq Master Mix Kit
- TurboAmp 25:1
- TurboAmp Hot Start (25:1, W3 2:1)
- TurboAmp Hot Start Taq (25:1, W3 1.6:1)
Protein information: Uniprot P19821 search for Taq pol I at UniProt
Sequence information: NCBI nucleotides European nucleotide archive
Predicted structure: AlphaFold DB entry AF-P19821-F1