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Reference: Fidelity and error specificity of the alpha catalytic subunit of Escherichia coli DNA polymerase III.

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Polymerase	Reference	Property	Result	Context
Human Pol alpha	Fidelity and error specificity of the alpha catalytic subunit of Escherichia coli DNA polymerase III.	3-5' Exonuclease (proofreading)	No
Human Pol alpha	Fidelity and error specificity of the alpha catalytic subunit of Escherichia coli DNA polymerase III.	Cloned or native	Cloned in E. coli
Human Pol alpha	Fidelity and error specificity of the alpha catalytic subunit of Escherichia coli DNA polymerase III.	Frameshift Error Rate	0.00031 errors/bp	Technique: Reversion
Human Pol alpha	Fidelity and error specificity of the alpha catalytic subunit of Escherichia coli DNA polymerase III.	Frameshift Error Rate	4E-05 errors/bp	Technique: Forward mutational
Human Pol alpha	Fidelity and error specificity of the alpha catalytic subunit of Escherichia coli DNA polymerase III.	Overall Error Rate	0.003 errors/bp	Technique: M13mp2 forward mutation assay
Human Pol alpha	Fidelity and error specificity of the alpha catalytic subunit of Escherichia coli DNA polymerase III.	Overall Error Rate	5E-05 errors/bp	Technique: Forward mutational
Human Pol alpha	Fidelity and error specificity of the alpha catalytic subunit of Escherichia coli DNA polymerase III.	Nucleotide Substitution Rate	1.3E-06 errors/bp	Technique: Reversion
Human Pol alpha	Fidelity and error specificity of the alpha catalytic subunit of Escherichia coli DNA polymerase III.	Nucleotide Substitution Rate	1.1E-05 errors/bp	Technique: Forward mutational
Human Pol alpha	Fidelity and error specificity of the alpha catalytic subunit of Escherichia coli DNA polymerase III.	Full length or truncated	Full length
Human Pol alpha	Fidelity and error specificity of the alpha catalytic subunit of Escherichia coli DNA polymerase III.	Specific Activity	4.5E+06 units/mg
Human Pol alpha	Fidelity and error specificity of the alpha catalytic subunit of Escherichia coli DNA polymerase III.	Gap Filling	Yes