Human Pol alpha
From
H. sapiens
(aliases:pol α, DNA polymerase alpha)
(genes: POLA1)
Welcome to the Polymerase Page
This page presents all the information in Polbase for Human Pol alpha.
Mutants:At the top of the page you'll find a map of all positions of known mutants. Text links to mutants and digestion products are listed in the Mutants section.
Structures/Sequence:If available, a representative structure is displayed at the upper right. All known structures are listed in the Structures section.
External links:Polbase polymerases are linked to UniProt and Genbank where possible. The UniProt search link directs you to a pre-constructed UniProt search containing relevant terms.
References:All references that refer to this Polymerase are listed with their topics and paper's title in the References table.
Results:All the results for this polymerase can be examined by following the "Results" link at the bottom of the page.
Help icons:
The symbol in the upper-right corner of the page
links to this help text. The question mark icon is used everywhere to indicate that help is available.
Human Pol alpha
is a family B enzyme
from
H. sapiens.
Selected Properties for Human Pol alpha: |
3'-5' exo activity | 5'-3' exo activity | Frameshift Rate | Substitution Rate | General Error Rate |
|---|---|---|---|---|---|
| No (5) | No (3) | 4.0e-05-3.1e-04 errors/bp (2) | 1.3e-06-2.6e-04 errors/bp (6) | 5.0e-05-3.0e-03 errors/bp (2) |
- References (171)
- Structures (3)
- Sequences (1)
- Mutants (2)...
- Formulations (0)
- Polymerase Lots (0)
- External links
| Year | Authors | Title | Results by property |
|---|---|---|---|
| P Hafkemeyer, K A Neftel, Ulrich Hübscher | HIV-reverse transcriptase and human D... | ||
| 2013 | Rajika L Perera, R Torella, Sebastian Klinge, Mairi L Kilkenny, JD Maman, Luca Pellegrini | Mechanism for priming DNA synthesis b... | |
| 2013 | Valentina Aria, Mariarita De Felice, Roberta Di Perna, Shuji Uno, Hisao Masai, Juhani E Syvaoja, Barbara van Loon, Ulrich Hubscher, Francesca M Pisani | The Human Tim/Tipin Complex Directly ... | |
| 2012 | Markku Vaara, Harri Itkonen, Tomi Hillukkala, Zhe Liu, Heinz Peter Nasheuer, Daniel Schaarschmidt, Helmut Pospiech, Juhani E Syväoja | Segregation of replicative DNA polyme... | |
| 2011 | Yoshiyuki Mizushina, Naoki Maeda, Isoko Kuriyama, Hiromi Yoshida | Dehydroaltenusin is a specific inhibi... | |
| 2011 | Ryuya Fujii, Atsushi Minami, Tae Tsukagoshi, Natsuko Sato, Takehiko Sahara, Satoru Ohgiya, Katsuya Gomi, Hideaki Oikawa | Total biosynthesis of diterpene aphid... | |
| 2011 | Barbara Zdrazil, Anja Schwanke, Birte Schmitz, Monika Schäfer-Korting, Hans-Dieter Höltje | Molecular modelling studies of new po... | |
| 2011 | Vladimir P Bermudez, A Farina, V Raghavan, Inger Tappin, Jerard Hurwitz | Studies on Human DNA Polymerase {epsi... | |
| 2011 | Yoshiyuki Mizushina, Jun Maeda, Yasuhiro Irino, Masayuki Nishida, Shin Nishiumi, Yasuyuki Kondo, Kazuyuki Nishio, Kouji Kuramochi, Kazunori Tsubaki, Isoko Kuriyama, Takeshi Azuma, Hiromi Yoshida, Masaru Yoshida | Effects of Intermediates between Vita... | |
| 2011 | Kazuki Kobayashi, Shin Nishiumi, Masayuki Nishida, Midori Hirai, Takeshi Azuma, Hiromi Yoshida, Yoshiyuki Mizushina, Masaru Yoshida | Effects of quinone derivatives, such ... | |
| 2010 | Shigeru Tanaka, Ke Cao, Atsuko Niimi, Siripan Limsirichaikul, Huang Qin Miao, Noriko Nakamura, Takashi Murate, Yoshinori Hasegawa, Tomonori Takahashi, Motoshi Suzuki | Functions of base selection step in h... | |
| 2010 | Mark D Sutton | Coordinating DNA polymerase traffic d... | |
| 2010 | Sandeep N Shah, Patricia L Opresko, Xiao Meng, Marietta Y W T Lee, Kristin A Eckert | DNA structure and the Werner protein ... | |
| 2010 | Linda J Reha-Krantz | DNA polymerase proofreading: Multiple... | |
| 2010 | Christopher Van, Shan Yan, W Matthew Michael, Shou Waga, Karlene A Cimprich | Continued primer synthesis at stalled... | |
| 2010 | Ken Hirano, Yuichiro Yoshida, Tomomi Ishido, Yukihisa Wada, Naoji Moriya, Naoshi Yamazaki, Yoshiyuki Mizushina, Yoshinobu Baba, Mitsuru Ishikawa | Consecutive incorporation of fluoroph... | |
| 2009 | Eric M Warren, Hao Huang, Ellen Fanning, Walter J Chazin, Brandt F Eichman | Physical interactions between Mcm10, ... | |
| 2009 | Shan Yan, W Matthew Michael | TopBP1 and DNA polymerase-alpha direc... | |
| 2009 | Tahir H Tahirov, Kira S Makarova, Igor B Rogozin, Youri I Pavlov, Eugene V Koonin | Evolution of DNA polymerases: an inac... | |
| 2009 | Yuki Matsui, Takahiko Hada, Naoki Maeda, Yoshihiro Sato, Yasuhiro Yamaguchi, Toshifumi Takeuchi, Masaharu Takemura, Fumio Sugawara, Kengo Sakaguchi, Hiromi Yoshida, Yoshiyuki Mizushina | Structure and activity relationship o... | |
| 2009 | Jennifer N Patro, Milan Urban, Robert D Kuchta | Role of the 2-amino group of purines ... | |
| 2009 | Gudrun Stengel, Byron W Purse, L Marcus Wilhelmsson, Milan Urban, Robert D Kuchta | Ambivalent incorporation of the fluor... | |
| 2009 | Jennifer N Patro, Milan Urban, Robert D Kuchta | Interaction of human DNA polymerase a... | |
| 2008 | Linda J Reha-Krantz | Recent patents of gene sequences rela... | |
| 2008 | PD Robertson, Eric M Warren, Haijiang Zhang, DB Friedman, JW Lary, JL Cole, AV Tutter, JC Walter, Ellen Fanning, Brandt F Eichman | Domain architecture and biochemical c... | |
| 2008 | Anja Richartz, Monika Höltje, Birte Brandt, Monika Schäfer-Korting, Hans-Dieter Höltje | Targeting human DNA polymerase alpha ... | |
| 2007 | Jeff W Beckman, Kristi Kincaid, Michal Hocek, Thomas E Spratt, Joachim W Engels, Richard Cosstick, Robert D Kuchta | Human DNA polymerase alpha uses a com... | |
| 2007 | Hirotomo Nakata, Masayuki Amano, Yasuhiro Koh, Eiichi N Kodama, Guangwei Yang, Christopher M Bailey, Satoru Kohgo, Hiroyuki Hayakawa, Masao Matsuoka, Karen S Anderson, Yung-Chi Cheng, Hiroyuki Mitsuya | Activity against human immunodeficien... | |
| 2007 | Mariarosaria De Falco, Elena Ferrari, Mariarita De Felice, Mosè Rossi, Ulrich Hübscher, Francesca M Pisani | The human GINS complex binds to and s... | |
| 2006 | Anna K Rytkönen, Tomi Hillukkala, Markku Vaara, Miiko Sokka, Maarit Jokela, Raija Sormunen, Heinz Peter Nasheuer, Tamar Nethanel, Gabriel Kaufmann, Helmut Pospiech, Juhani E Syväoja | DNA polymerase epsilon associates wit... | |
| 2005 | Tomonori Takahashi, Zhenghua Min, Iichiro Uchida, Michitsune Arita, Yoh Watanabe, Minoru Koi, Hiromichi Hemmi | Hypersensitivity in DNA mismatch repa... | |
| 2005 | William T Wolfle, Robert E Johnson, Irina G Minko, R Stephen Lloyd, Satya Prakash, Louise Prakash | Human DNA polymerase iota promotes re... | |
| 2005 | Emmanuele Crespan, Samantha Zanoli, Anastasiya Khandazhinskaya, Igor V Shevelev, Maxim Jasko, Ludmila Alexandrova, Marina Kukhanova, Giuseppina Blanca, Giuseppe Villani, Ulrich Hübscher, Silvio Spadari, Giovanni Maga | Incorporation of non-nucleoside triph... | |
| 2004 | Katherine A Richardson, Tanya P Vega, Frank C Richardson, Chad L Moore, John C Rohloff, Blake Tomkinson, Raymond A Bendele, Robert D Kuchta | Polymerization of the triphosphates o... | |
| 2004 | Youri I Pavlov, Satoko Maki, Hisaji Maki, Thomas A Kunkel | Evidence for interplay among yeast re... | 3-5' exo,5-3' exo,All properties |
| 2004 | Naomi Suzuki, Manabu Yasui, Y R Santosh Laxmi, Haruo Ohmori, Fumio Hanaoka, Shinya Shibutani | Translesion synthesis past equine est... | |
| 2003 | Molly Chiaramonte, Chad L Moore, Kristi Kincaid, Robert D Kuchta | Facile polymerization of dNTPs bearin... | |
| 2003 | Ferenc Evanics, Leila Maurmann, Wei Wen Yang, Rathindra N Bose | Nuclear magnetic resonance structures... | |
| 2003 | Siripan Limsirichaikul, Masanori Ogawa, Atsuko Niimi, Shigenori Iwai, Takashi Murate, Shonen Yoshida, Motoshi Suzuki | The Gly-952 residue of Saccharomyces ... | |
| 2002 | Richard W P Smith, Claudia Steffen, Frank Grosse, Heinz Peter Nasheuer | Species specificity of simian virus 4... | |
| 2002 | Robert D Ott, Christoph Rehfuess, Vladimir N Podust, Jill E Clark, Ellen Fanning | Role of the p68 subunit of human DNA ... | |
| 2002 | Ulrich Hubscher, Giovanni Maga, Silvio Spadari | Eukaryotic DNA polymerases. | |
| 2001 | Phillip A Furman, J Jeffrey, L L Kiefer, Joy Y Feng, Karen S Anderson, K Borroto-Esoda, E Hill, William C Copeland, Chung K Chu, J P Sommadossi, I Liberman, Raymond F Schinazi, George R Painter | Mechanism of action of 1-beta-D-2,6-d... | |
| 2000 | Frank C Richardson, Robert D Kuchta, A Mazurkiewicz, Katherine A Richardson | Polymerization of 2'-fluoro- and 2'-O... | |
| 2000 | T Niki, I Galli, H Ariga, S M Iguchi-Ariga | MSSP, a protein binding to an origin ... | |
| 2000 | Eiji Ohashi, Katarzyna Bebenek, Toshiro Matsuda, William J Feaver, Valerie L Gerlach, Errol C Friedberg, Haruo Ohmori, Thomas A Kunkel | Fidelity and processivity of DNA synt... | Nucleotide Substitution Rate,All properties |
| 1999 | C Voitenleitner, Christoph Rehfuess, M Hilmes, L O'Rear, P C Liao, D A Gage, Robert Ott, Heinz Peter Nasheuer, Ellen Fanning | Cell cycle-dependent regulation of hu... | |
| 1999 | E Efrati, G Tocco, R Eritja, Samuel H Wilson, Myron F Goodman | "Action-at-a-distance" mutagenesis. 8... | |
| 1999 | J M de Muys, H Gourdeau, N Nguyen-Ba, D L Taylor, P S Ahmed, T Mansour, C Locas, N Richard, Mark A. Wainberg, R F Rando | Anti-human immunodeficiency virus typ... | |
| 1999 | K L Conger, Jen-Sing Liu, Shu-Ru Kuo, L T Chow, Teresa S-F Wang | Human papillomavirus DNA replication.... | |
| 1999 | Thomas A Steitz | DNA polymerases: structural diversity... | |
| 1998 | A Schneider, Richard W P Smith, A R Kautz, Klaus Weisshart, Frank Grosse, Heinz Peter Nasheuer | Primase activity of human DNA polymer... | |
| 1998 | A Tomikawa, M Seno, K Sato-Kiyotaki, C Ohtsuki, T Hirai, Tsuyoshi Yamaguchi, T Kawaguchi, Shonen Yoshida, Mineo Saneyoshi | Synthetic nucleosides and nucleotides... | |
| 1998 | S G Huang, Klaus Weisshart, I Gilbert, Ellen Fanning | Stoichiometry and mechanism of assemb... | |
| 1997 | Ashwini S Kamath-Loeb, A Hizi, Hironori Kasai, Lawrence A Loeb | Incorporation of the guanosine tripho... | |
| 1997 | V Gandhi, P Huang, A J Chapman, F Chen, W Plunkett | Incorporation of fludarabine and 1-be... | |
| 1997 | E Efrati, G Tocco, R Eritja, Samuel H Wilson, Myron F Goodman | Abasic translesion synthesis by DNA p... | |
| 1996 | T I Kolocheva, G A Maksakova, O D Zakharova, G A Nevinsky | The algorithm of estimation of the Km... | |
| 1996 | F B Perler, Sandeep Kumar, H Kong | Thermostable DNA polymerases. | Full length or truncated,3-5' exo,5-3' exo,All properties |
| 1996 | J Y Mo, Roel M Schaaper | Fidelity and error specificity of the... | Cloned or native,Full length or truncated,Specific Activity,Gap fill,3-5' exo,Frameshift Error Rate,Nucleotide Substitution Rate,Overall Error Rate,All properties |
| 1995 | Hiroyuki Kamiya, Hironori Kasai | Formation of 2-hydroxydeoxyadenosine ... | KM,Vmax,All properties |
| 1995 | Federico Focher, Giovanni Maga, A Bendiscioli, M Capobianco, F Colonna, A Garbesi, Silvio Spadari | Stereospecificity of human DNA polyme... | |
| 1995 | Hiroyuki Kamiya, Tadamasa Ueda, T Ohgi, Akio Matsukage, Hironori Kasai | Misincorporation of dAMP opposite 2-h... | |
| 1995 | T H Broschard, M Wiessler, H H Schmeiser | Effect of site-specifically located a... | |
| 1995 | T Melendy, Juhan Sedman, A Stenlund | Cellular factors required for papillo... | |
| 1995 | R R Vyas, A K Basu | DNA polymerase action on an oligonucl... | |
| 1995 | D G Semizarov, M V Ias'ko, M K Kukhanova, A A Kraevskiĭ | [New nucleotide inhibitors of human D... | |
| 1995 | Q Dong, Teresa S-F Wang | Mutational studies of human DNA polym... | |
| 1994 | P Hentosh, P Grippo | Template 2-chloro-2'-deoxyadenosine m... | |
| 1994 | S Niranjanakumari, K P Gopinathan | DNA polymerase alpha-primase complex ... | |
| 1994 | Shonen Yoshida, C M Simbulan | Interaction of poly(ADP-ribose)polyme... | |
| 1993 | William C Copeland, Teresa S-F Wang | Mutational analysis of the human DNA ... | |
| 1993 | Svetlana N Khodyreva, Vladimir N Podust, D S Sergeev, E M Ivanova, E I Frolova, A A Koshkin, T S Godovikova, V F Zarytova, Miria Ricchetti, Olga I Lavrik | Comparison of interactions of 5'-deri... | |
| 1993 | Q Dong, William C Copeland, Teresa S-F Wang | Mutational studies of human DNA polym... | |
| 1993 | K L Collins, A A Russo, B Y Tseng, T J Kelly | The role of the 70 kDa subunit of hum... | |
| 1993 | I Dornreiter, William C Copeland, Teresa S-F Wang | Initiation of simian virus 40 DNA rep... | |
| 1993 | William C Copeland, N K Lam, Teresa S-F Wang | Fidelity studies of the human DNA pol... | |
| 1993 | Kristin A Eckert, Thomas A Kunkel | Fidelity of DNA synthesis catalyzed b... | Cloned or native,Full length or truncated,Specific Activity,Nucleotide Substitution Rate,All properties |
| 1993 | Q Dong, William C Copeland, Teresa S-F Wang | Mutational studies of human DNA polym... | |
| 1993 | G Bialek, Frank Grosse | An error-correcting proofreading exon... | |
| 1993 | Vladimir N Podust, Ulrich Hübscher | Lagging strand DNA synthesis by calf ... | |
| 1993 | M S Chen, R T Suttmann, E Papp, P D Cannon, M J McRoberts, C Bach, William C Copeland, Teresa S-F Wang | Selective action of 4'-azidothymidine... | |
| 1992 | Dmitry A Gordenin, A L Malkova, A Peterzen, V N Kulikov, Youri I Pavlov, E Perkins, Michael A Resnick | Transposon Tn5 excision in yeast: inf... | |
| 1992 | Silvio Spadari, Federico Focher, Ulrich Hübscher | Developmental activity profile of DNA... | |
| 1992 | DNA Replication | ||
| 1992 | H Hao, Yanan Jiang, S J Zhang, Peiming Zhang, R X Zeng, Marietta Y W T Lee | Structural and functional relationshi... | |
| 1992 | William C Copeland, M S Chen, Teresa S-F Wang | Human DNA polymerases alpha and beta ... | Cloned or native,Tagged,Full length or truncated,KM,Kd,Vmax,Application name,Incorporation of non-standard nucleotides,All properties |
| 1992 | Fred W Perrino, H L Mekosh | Incorporation of cytosine arabinoside... | |
| 1992 | S V Doronin, M I Dobrikov, Olga I Lavrik | Photoaffinity labeling of DNA polymer... | |
| 1992 | J A Burrows, C R Goward | Purification and properties of DNA po... | |
| 1991 | T Weiser, M Gassmann, P Thömmes, Elena Ferrari, P Hafkemeyer, Ulrich Hübscher | Biochemical and functional comparison... | Specific Activity,Processivity,3-5' exo,5-3' exo,RNase H,All properties |
| 1991 | Heinz Peter Nasheuer, A Moore, A F Wahl, Teresa S-F Wang | Cell cycle-dependent phosphorylation ... | |
| 1991 | N N Khan, George E Wright, Neal C Brown | The molecular mechanism of inhibition... | |
| 1991 | P A Leegwater, M Strating, N B Murphy, R F Kooy, Peter C van der Vliet, J P Overdulve | The Trypanosoma brucei DNA polymerase... | |
| 1991 | P Hafkemeyer, K Neftel, R Hobi, A Pfaltz, H Lutz, K Lüthi, Federico Focher, Silvio Spadari, Ulrich Hübscher | HP 0.35, a cephalosporin degradation ... | |
| 1991 | Alessandra Montecucco, M Fontana, Federico Focher, M Lestingi, Silvio Spadari, G Ciarrocchi | Specific inhibition of human DNA liga... | |
| 1991 | K B Frank, G J Noll, E V Connell, I S Sim | Kinetic interaction of human immunode... | |
| 1991 | William C Copeland, Teresa S-F Wang | Catalytic subunit of human DNA polyme... | |
| 1990 | G A Nevinskiĭ, I A Potapova, N B Tarusova, O V Khalabuda, V V Khomov | [Interaction of dNTP-binding sites of... | |
| 1990 | K L Hsi, William C Copeland, Teresa S-F Wang | Human DNA polymerase alpha catalytic ... | |
| 1990 | Y Tsutsumi, S Hori, N Onoda | DNA polymerase alpha. An immunohistoc... | |
| 1990 | Peter M J Burgers, Robert A Bambara, Judith L Campbell, L M Chang, Kathleen M Downey, Ulrich Hübscher, Marietta Y W T Lee, Stuart Linn, Antero G So, Silvio Spadari | Revised nomenclature for eukaryotic D... | |
| 1990 | I A Potapova, G A Nevinsky, A G Veniaminova, V V Khomov, Olga I Lavrik | Interaction of dNTP, pyrophosphate an... | |
| 1990 | Vladimir N Podust, T O Korobeinicheva, G A Nevinsky, A S Levina, Olga I Lavrik | Inactivation of DNA polymerase by ade... | |
| 1990 | T Matsumoto, Toshihiko Eki, Jerard Hurwitz | Studies on the initiation and elongat... | |
| 1989 | J E Reardon | Herpes simplex virus type 1 and human... | |
| 1989 | Olga I Lavrik, G A Nevinskiĭ, I A Potapova, N B Tarusova, O V Khalabuda | [Modification of human DNA polymerase... | |
| 1989 | A Morrison, R B Christensen, J Alley, A K Beck, E G Bernstine, J F Lemontt, Christopher W Lawrence | REV3, a Saccharomyces cerevisiae gene... | |
| 1989 | L Ng, S J Weiss, Paul A Fisher | Recognition and binding of template-p... | |
| 1989 | Vladimir N Podust, Olga I Lavrik, Heinz Peter Nasheuer, Frank Grosse | DNA polymerase alpha-DNA primase from... | |
| 1989 | Federico Focher, M Gassmann, P Hafkemeyer, Elena Ferrari, Silvio Spadari, Ulrich Hübscher | Calf thymus DNA polymerase delta inde... | |
| 1988 | S W Wong, A F Wahl, P M Yuan, N Arai, B E Pearson, K Arai, D Korn, M W Hunkapiller, Teresa S-F Wang | Human DNA polymerase alpha gene expre... | 3-5' exo,All properties |
| 1988 | H Nakane, Jan Balzarini, Erik De Clercq, K Ono | Differential inhibition of various de... | |
| 1988 | J D Roberts, Thomas A Kunkel | Fidelity of a human cell DNA replicat... | |
| 1987 | R Namikawa, T Suchi, R Ueda, G Itoh, K Koike, K Ota, T Takahashi | Phenotyping of proliferating lymphocy... | |
| 1987 | M S Boosalis, John Petruska, Myron F Goodman | DNA polymerase insertion fidelity. Ge... | KM,Vmax,All properties |
| 1987 | Olga I Lavrik, A S Levina, G A Nevinsky, Vladimir N Podust | Role of nucleoside components and int... | |
| 1987 | R W Donaldson, E W Gerner | Phosphorylation of a high molecular w... | |
| 1987 | R Namikawa, R Ueda, T Suchi, G Itoh, K Ota, T Takahashi | Double immunoenzymatic detection of s... | |
| 1987 | G A Nevinskiĭ, S V Doronin, Vladimir N Podust, Olga I Lavrik | [Effectiveness of complex-formation o... | |
| 1986 | Hiroshi Miyazawa, M Tandai, Fumio Hanaoka, Masami Yamada, T Hori, Kikuo Shimizu, M Sekiguchi | Identification of a DNA segment conta... | |
| 1986 | L Kaczmarek, M R Miller, R A Hammond, W E Mercer | A microinjected monoclonal antibody a... | |
| 1986 | Marietta Y W T Lee, N L Toomey | Differential effects of dimethylsulfo... | |
| 1986 | M Tsuda, M Masuyama, T Katsunuma | Inhibition of human DNA polymerase al... | |
| 1985 | C W Greider, E H Blackburn | Identification of a specific telomere... | |
| 1985 | M R Miller, R G Ulrich, Teresa S-F Wang, D Korn | Monoclonal antibodies against human D... | |
| 1984 | Fumio Hanaoka, M Tandai, Hiroshi Miyazawa, Y Murakami, T Hori, Masami Yamada | Human DNA polymerase alpha. Compensat... | |
| 1983 | J A Hall, R Saffhill | The incorporation of O6-methyldeoxygu... | |
| 1982 | Ulrich Hübscher, P Gerschwiler, G K McMaster | A mammalian DNA polymerase alpha holo... | |
| 1982 | Shigeru Tanaka, S Z Hu, Teresa S-F Wang, D Korn | Preparation and preliminary character... | |
| 1982 | K G Bensch, Shigeru Tanaka, S Z Hu, Teresa S-F Wang, D Korn | Intracellular localization of human D... | |
| 1981 | M Geuskens, N Hardt, G Pedrali-Noy, Silvio Spadari | An autoradiographic demonstration of ... | |
| 1981 | Paul A Fisher, D Korn | Ordered sequential mechanism of subst... | |
| 1981 | F Sala, M G Galli, M Levi, D Burroni, B Parisi, G Pedrali-Noy, Silvio Spadari | Functional roles of the plant alpha-l... | |
| 1980 | G Pedrali-Noy, Silvio Spadari, A Miller-Faurès, A O Miller, J Kruppa, G Koch | Synchronization of HeLa cell cultures... | |
| 1980 | G Pedrali-Noy, Silvio Spadari | Mechanism of inhibition of herpes sim... | |
| 1980 | George E Wright, E F Baril, Neal C Brown | Butylanilinouracil: a selective inhib... | |
| 1980 | F Sala, B Parisi, D Burroni, A R Amileni, G Pedrali-Noy, Silvio Spadari | Specific and reversible inhibition by... | |
| 1979 | P F Pignatti, E Cassai, U Bertazzoni | Herpes simplex virus DNA synthesis in... | |
| 1979 | Paul A Fisher, Teresa S-F Wang, D Korn | Enzymological characterization of DNA... | Full length or truncated,Processivity,Nick Extension,Gap fill,KM,All properties |
| 1979 | G Pedrali-Noy, Silvio Spadari | Effect of aphidicolin on viral and hu... | |
| 1979 | Y Ono, Takemi Enomoto, Masami Yamada | Variation of two forms of DNA polymer... | |
| 1979 | Ulrich Hübscher, C C Kuenzle, W Limacher, P Scherrer, Silvio Spadari | Functions of DNA polymerases alpha, b... | |
| 1978 | P Bhattacharya, S Basu | DNA polymerase activities in differen... | |
| 1978 | Mochihiko Ohashi, Takahiko Taguchi, S Ikegami | Aphidicolin: a specific inhibitor of ... | |
| 1978 | R Dicioccio, B I Srivastava | Inhibition of deoxyribonucleic acid p... | |
| 1978 | B Novak, E F Baril | HeLa DNA polymerase alpha activity in... | |
| 1978 | T Shimada, Masami Yamada, M Miwa, H Nagano, Y Mano | Differential susceptibilities of DNA ... | |
| 1978 | M A Waqar, M J Evans, J A Huberman | Effect of 2',3'-dideoxythymidine-5'-t... | |
| 1977 | D C Eichler, Paul A Fisher, D Korn | Effect of calcium on the recovery and... | |
| 1977 | Paul A Fisher, D Korn | DNA polymerase-alpha. Purification an... | |
| 1977 | Ulrich Hübscher, C C Kuenzle, Silvio Spadari | Variation of DNA polymerases-alpha, -... | |
| 1976 | U Bertazzoni, M Stefanini, G P Noy, E Giulotto, F Nuzzo, A Falaschi, Silvio Spadari | Variations of DNA polymerase-alpha an... | |
| 1976 | G Herrick, B B Spear, G Veomett | Intracellular localization of mouse D... | |
| 1975 | Silvio Spadari, A Weissbach | RNA-primed DNA synthesis: specific ca... | |
| 1975 | R G Smith, J W Abrell, B J Lewis, R C Gallo | Serological analysis of human deoxyri... | |
| 1975 | G M Brun, L M Assairi, F Chapeville | Immunological relationships between c... | |
| 1975 | R W Chiu, E F Baril | Nuclear DNA polymerases and the HeLa ... | |
| 1975 | R J Mayer, R G Smith, R C Gallo | DNA-metabolizing enzymes in normal hu... | |
| 1974 | Silvio Spadari, R Muller, A Weissbach | The dissimilitude of the low and high... | |
| 1974 | Silvio Spadari, A Weissbach | The interrelation between DNA synthes... | |
| 1973 | E F Baril, M D Jenkins, O E Brown, J Laszlo, H P Morris | DNA polymerases I and II in regenerat... | |
| 1973 | N B Hecht | Interconvertibility of mouse DNA poly... | |
| 1973 | L H Lazarus, N Kitron | Letter: Cytoplasmic DNA polymerase: p... | |
| 1973 | R A Bucknall, H Moores, R Simms, B Hesp | Antiviral effects of aphidicolin, a n... | |
| 1973 | L M Chang, M Brown, F J Bollum | Induction of DNA polymerase in mouse ... | |
| 1972 | L M Chang, F J Bollum | Antigenic relationships in mammalian ... | |
| 1972 | B Fridlender, M Fry, A Bolden, A Weissbach | A new synthetic RNA-dependent DNA pol... | |
| 1965 | M YONEDA, F J Bollum | DEOXYNUCLEOTIDE-POLYMERIZING ENZYMES ... | Optimal pH,All properties |
| 1956 | M FRIEDKIN, D TILSON, D ROBERTS | Studies of deoxyribonucleic acid bios... | |
| 1956 | M FRIEDKIN, H I V WOOD | Utilization of thymidine-C14 by bone ... |
Protein sequence:
| Name | 3'-5' exo activity | 5'-3' exo activity | Frameshift Rate | Substitution Rate | General Error Rate |
|---|---|---|---|---|---|
| pol alpha L864F | |||||
| pol alpha G952A |
Protein information: Uniprot P09884 search for Human Pol alpha at UniProt
Sequence information: NCBI nucleotides European nucleotide archive