Cell cycle-specific expression and nuclear binding of DNA polymerase alpha.

Abstract:

The expression and distribution of DNA polymerase alpha was measured ...
The expression and distribution of DNA polymerase alpha was measured by cytometry and confocal laser scanning microscopy. Expression was proportional to DNA content in proliferating cells, while only S-phase cells retained DNA polymerase alpha after detergent extraction. Nuclear DNA polymerase alpha binding may be one of the key events of S-phase entry.

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