Gastrointestinal hyperplasia with altered expression of DNA polymerase beta.

Yoshizawa K, Jelezcova E, Brown AR, Foley JF, Nyska A, Cui X, Hofseth LJ, Maronpot RM, Wilson SH, Sepulveda AR, Sobol RW
PloS one (2009), Volume 4, Page e6493
PubMed entry Full article text Publisher's site

Abstract:

Altered expression of DNA polymerase beta (Pol beta) has been ...
Altered expression of DNA polymerase beta (Pol beta) has been documented in a large percentage of human tumors. However, tumor prevalence or predisposition resulting from Pol beta over-expression has not yet been evaluated in a mouse model.

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