Hydrogen bonding revisited: geometric selection as a principal determinant of DNA replication fidelity.




Nucleotide Incorporation, Exonuclease Activity, Nucleotide Analogs / Template Lesions, Fidelity

One line summary:

Hydrogen bonding is not completely essential in the formation of base pairs, difluorotoulene proves this case as a non H-bonding structural facsimile of thymine


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