Proceedings of the National Academy of Sciences of the United States of America

(Proc Natl Acad Sci U S A) ISSNs: , 1091-6490

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Title	Authors	Year
DNA polymerase I gene of Saccharomyces cerevisiae: nucleotide sequence, mapping of a temperature-sensitive mutation, and protein homology with other DNA polymerases.	Pizzagalli A, Valsasnini P, Plevani P, Lucchini G	1988
Intervening sequences in an Archaea DNA polymerase gene.	Perler FB, Comb DG, Jack WE, Moran LS, Qiang B, Kucera RB, Benner J, Slatko BE, Nwankwo DO, Hempstead SK	1992
Computer analysis of retroviral pol genes: assignment of enzymatic functions to specific sequences and homologies with nonviral enzymes.	Johnson MS, McClure MA, Feng DF, Gray J, Doolittle RF	1986
Mechanism of DNA chain growth. I. Possible discontinuity and unusual secondary structure of newly synthesized chains.	Okazaki R, Okazaki T, Sakabe K, Sugimoto K, Sugino A	1968
Mitochondrial DNA polymerase editing mutation, PolgD257A, reduces the diabetic phenotype of Akita male mice by suppressing appetite.	Fox R, Kim HS, Reddick RL, Kujoth GC, Prolla TA, Tsutsumi S, Wada Y, Smithies O, Maeda N	2011
Correlation of somatic hypermutation specificity and A-T base pair substitution errors by DNA polymerase eta during copying of a mouse immunoglobulin kappa light chain transgene.	Pavlov YI, Rogozin IB, Galkin AP, Aksenova AY, Hanaoka F, Rada C, Kunkel TA	2002
DNA polymerase beta bypasses in vitro a single d(GpG)-cisplatin adduct placed on codon 13 of the HRAS gene.	Hoffmann JS, Pillaire MJ, Maga G, Podust V, Hübscher U, Villani G	1995
Capacity of RecA protein to bind preferentially to UV lesions and inhibit the editing subunit (epsilon) of DNA polymerase III: a possible mechanism for SOS-induced targeted mutagenesis.	Lu C, Scheuermann RH, Echols H	1986
The arginine finger of bacteriophage T7 gene 4 helicase: role in energy coupling.	Crampton DJ, Guo S, Johnson DE, Richardson CC	2004
Crystal structures of 2-acetylaminofluorene and 2-aminofluorene in complex with T7 DNA polymerase reveal mechanisms of mutagenesis.	Dutta S, Li Y, Johnson DE, Dzantiev L, Richardson CC, Romano LJ, Ellenberger T	2004
Molecular cloning and expression of the Saccharomyces cerevisiae RFC3 gene, an essential component of replication factor C.	Li X, Burgers PM	1994
Analysis of cytokine mRNA and DNA: detection and quantitation by competitive polymerase chain reaction.	Gilliland G, Perrin S, Blanchard K, Bunn HF	1990
A genetic system to identify DNA polymerase beta mutator mutants.	Washington SL, Yoon MS, Chagovetz AM, Li SX, Clairmont CA, Preston BD, Eckert KA, Sweasy JB	1997
Mutants in the Exo I motif of Escherichia coli dnaQ: defective proofreading and inviability due to error catastrophe.	Fijalkowska I, Schaaper RM	1996
Heterogeneity of primer extension products in asymmetric PCR is due both to cleavage by a structure-specific exo/endonuclease activity of DNA polymerases and to premature stops.	Tombline G, Bellizzi D, Sgaramella V	1996
Human coronavirus NL63 employs the severe acute respiratory syndrome coronavirus receptor for cellular entry.	Hofmann H, Pyrc K, van der Hoek L, Geier M, Berkhout B, Pöhlmann S	2005
Replication by a single DNA polymerase of a stretched single-stranded DNA.	Maier B, Bensimon D, Croquette V	2000
Comparison of the 5' nuclease activities of taq DNA polymerase and its isolated nuclease domain.	Lyamichev V, Brow MA, Varvel VE, Dahlberg JE	1999
Eukaryotic DNA polymerase amino acid sequence required for 3'----5' exonuclease activity.	Morrison A, Bell JB, Kunkel TA, Sugino A	1991
A phenotype for enigmatic DNA polymerase II: a pivotal role for pol II in replication restart in UV-irradiated Escherichia coli.	Rangarajan S, Woodgate R, Goodman MF	1999
HOMOLOGY BETWEEN RNA FROM ROUS SARCOMA VIROUS AND DNA FROM ROUS SARCOMA VIRUS-INFECTED CELLS.	TEMIN HM	1964
Proofreading DNA: recognition of aberrant DNA termini by the Klenow fragment of DNA polymerase I.	Carver TE, Hochstrasser RA, Millar DP	1994
Crystal structure of the large fragment of Thermus aquaticus DNA polymerase I at 2.5-A resolution: structural basis for thermostability.	Korolev S, Nayal M, Barnes WM, Di Cera E, Waksman G	1995
DNA polymerase activities in differentiating mouse neuroblastoma N-18 cells.	Bhattacharya P, Basu S	1978
DNA polymerase II is encoded by the DNA damage-inducible dinA gene of Escherichia coli.	Bonner CA, Hays S, McEntee K, Goodman MF	1990
Site-specifically modified oligodeoxyribonucleotides as templates for Escherichia coli DNA polymerase I.	O'Connor D, Stöhrer G	1985
Proofreading-defective DNA polymerase II increases adaptive mutation in Escherichia coli.	Foster PL, Gudmundsson G, Trimarchi JM, Cai H, Goodman MF	1995
Alternate pathways of DNA replication: DNA polymerase I-dependent replication.	Niwa O, Bryan SK, Moses RE	1981
DNA polymerase III gene of Bacillus subtilis.	Sanjanwala B, Ganesan AT	1989
Proofreading by the epsilon subunit of Escherichia coli DNA polymerase III increases the fidelity of calf thymus DNA polymerase alpha.	Perrino FW, Loeb LA	1989
Ubiquitin-binding motif of human DNA polymerase eta is required for correct localization.	Sabbioneda S, Green CM, Bienko M, Kannouche PL, Dikic I, Lehmann AR	2009
Expression in Escherichia coli of a fusion protein product containing a region of the adenovirus DNA polymerase.	Rekosh D, Lindenbaum J, Brewster J, Mertz LM, Hurwitz J, Prestine L	1985
A peptide switch regulates DNA polymerase processivity.	López de Saro FJ, Georgescu RE, O'Donnell ME	2003
The enzymatic repair of DNA. I. Formation of circular lambda-DNA.	Gefter ML, Becker A, Hurwitz J	1967
Exchange of DNA polymerases at the replication fork of bacteriophage T7.	Johnson DE, Takahashi M, Hamdan SM, Lee SJ, Richardson CC	2007
Enzymatic synthesis of DNA. 23. Synthesis of circular replicative form of phage phi-X174 DNA.	Goulian M, Kornberg A	1967
Overproduction of the epsilon subunit of DNA polymerase III counteracts the SOS mutagenic response of Escherichia coli.	Jonczyk P, Fijalkowska I, Ciesla Z	1988
The many faces of DNA polymerases: strategies for mutagenesis and for mutational avoidance.	Friedberg EC, Feaver WJ, Gerlach VL	2000
UmuD'(2)C is an error-prone DNA polymerase, Escherichia coli pol V.	Tang M, Shen X, Frank EG, O'Donnell ME, Woodgate R, Goodman MF	1999
Mechanism of DNA elongation catalyzed by Escherichia coli DNA polymerase III, dnaZ protein, and DNA elongation factors I and III.	Wickner S	1976
The highly conserved amino acid sequence motif Tyr-Gly-Asp-Thr-Asp-Ser in alpha-like DNA polymerases is required by phage phi 29 DNA polymerase for protein-primed initiation and polymerization.	Bernad A, Lázaro JM, Salas M, Blanco L	1990
Isothermal in vitro amplification of DNA by a restriction enzyme/DNA polymerase system.	Walker GT, Little MC, Nadeau JG, Shank DD	1992
Cloning of thermostable DNA polymerases from hyperthermophilic marine Archaea with emphasis on Thermococcus sp. 9 degrees N-7 and mutations affecting 3'-5' exonuclease activity.	Southworth MW, Kong H, Kucera RB, Ware J, Jannasch HW, Perler FB	1996
Tuning and switching a DNA polymerase motor with mechanical tension.	Goel A, Astumian RD, Herschbach D	2003
Dissection of functional domains of adenovirus DNA polymerase by linker-insertion mutagenesis.	Chen M, Horwitz MS	1989
Suppression of chemical mutagenesis in bacteriophage T4 by genetically modified DNA polymerases.	Drake JW, Greening EO	1970
Unique features in the structure of the complex between HIV-1 reverse transcriptase and the bis(heteroaryl)piperazine (BHAP) U-90152 explain resistance mutations for this nonnucleoside inhibitor.	Esnouf RM, Ren J, Hopkins AL, Ross CK, Jones EY, Stammers DK, Stuart DI	1997
Exonucleolytic proofreading of leading and lagging strand DNA replication errors.	Roberts JD, Thomas DC, Kunkel TA	1991
Cell-cycle dependence and properties of the HeLa cell DNA polymerase system.	Delfini C, Alfani E, De Venezia V, Oberholtzer G, Tomasello C, Eremenko T, Volpe P	1985
Intracellular metabolism and mechanism of anti-retrovirus action of 9-(2-phosphonylmethoxyethyl)adenine, a potent anti-human immunodeficiency virus compound.	Balzarini J, Hao Z, Herdewijn P, Johns DG, De Clercq E	1991
Hydroxyl radical footprint analysis of human immunodeficiency virus reverse transcriptase-template.primer complexes.	Metzger W, Hermann T, Schatz O, Le Grice SF, Heumann H	1993
Mismatch-specific thymine DNA glycosylase and DNA polymerase beta mediate the correction of G.T mispairs in nuclear extracts from human cells.	Wiebauer K, Jiricny J	1990
The fifth essential DNA polymerase phi in Saccharomyces cerevisiae is localized to the nucleolus and plays an important role in synthesis of rRNA.	Shimizu K, Kawasaki Y, Hiraga S, Tawaramoto M, Nakashima N, Sugino A	2002
Processive DNA synthesis observed in a polymerase crystal suggests a mechanism for the prevention of frameshift mutations.	Johnson SJ, Taylor JS, Beese LS	2003
Properties of a soluble DNA polymerase isolated from Rous sarcoma virus.	Duesberg P, Helm KV, Canaani E	1971
Low levels of deoxynucleotides in peripheral blood lymphocytes: a strategy to inhibit human immunodeficiency virus type 1 replication.	Gao WY, Cara A, Gallo RC, Lori F	1993
Extension of mismatched 3' termini of DNA is a major determinant of the infidelity of human immunodeficiency virus type 1 reverse transcriptase.	Perrino FW, Preston BD, Sandell LL, Loeb LA	1989
Domain structure of the Moloney murine leukemia virus reverse transcriptase: mutational analysis and separate expression of the DNA polymerase and RNase H activities.	Tanese N, Goff SP	1988
Comparison between DNA melting thermodynamics and DNA polymerase fidelity.	Petruska J, Goodman MF, Boosalis MS, Sowers LC, Cheong C, Tinoco I	1988
Deoxynucleoside [1-thio]triphosphates prevent proofreading during in vitro DNA synthesis.	Kunkel TA, Eckstein F, Mildvan AS, Koplitz RM, Loeb LA	1981
Thermostable DNA polymerase chain amplification of t(14;18) chromosome breakpoints and detection of minimal residual disease.	Crescenzi M, Seto M, Herzig GP, Weiss PD, Griffith RC, Korsmeyer SJ	1988
The influence of neighboring base pairs upon base-pair substitution mutation rates.	Koch RE	1971
Sensitivity of wild-type human immunodeficiency virus type 1 reverse transcriptase to dideoxynucleotides depends on template length; the sensitivity of drug-resistant mutants does not.	Boyer PL, Tantillo C, Jacobo-Molina A, Nanni RG, Ding J, Arnold E, Hughes SH	1994
Targeting of human DNA polymerase iota to the replication machinery via interaction with PCNA.	Haracska L, Johnson RE, Unk I, Phillips BB, Hurwitz J, Prakash L, Prakash S	2001
Overexpression of DNA polymerase beta in cell results in a mutator phenotype and a decreased sensitivity to anticancer drugs.	Canitrot Y, Cazaux C, Fréchet M, Bouayadi K, Lesca C, Salles B, Hoffmann JS	1998
Directed evolution of novel polymerase activities: mutation of a DNA polymerase into an efficient RNA polymerase.	Xia G, Chen L, Sera T, Fa M, Schultz PG, Romesberg FE	2002
Fidelity of DNA polymerases in DNA amplification.	Keohavong P, Thilly WG	1989
Variations of DNA polymerase-alpha and -beta during prolonged stimulation of human lymphocytes.	Bertazzoni U, Stefanini M, Noy GP, Giulotto E, Nuzzo F, Falaschi A, Spadari S	1976
A beta-like DNA polymerase activity in the slime mold Dictyostelium discoideum.	Baril EF, Scheiner C, Pederson T	1980
Functional interaction between the Werner Syndrome protein and DNA polymerase delta.	Kamath-Loeb AS, Johansson E, Burgers PM, Loeb LA	2000
A structural gap in Dpo4 supports mutagenic bypass of a major benzo[a]pyrene dG adduct in DNA through template misalignment.	Bauer J, Xing G, Yagi H, Sayer JM, Jerina DM, Ling H	2007
A single mutation in poliovirus RNA-dependent RNA polymerase confers resistance to mutagenic nucleotide analogs via increased fidelity.	Pfeiffer JK, Kirkegaard K	2003
Mice reconstituted with DNA polymerase beta-deficient fetal liver cells are able to mount a T cell-dependent immune response and mutate their Ig genes normally.	Esposito G, Texido G, Betz UA, Gu H, Müller W, Klein U, Rajewsky K	2000
Degradation of DNA RNA hybrids by ribonuclease H and DNA polymerases of cellular and viral origin.	Keller W, Crouch R	1972
The Escherichia coli SOS mutagenesis proteins UmuD and UmuD' interact physically with the replicative DNA polymerase.	Sutton MD, Opperman T, Walker GC	1999
Random mutagenesis of Thermus aquaticus DNA polymerase I: concordance of immutable sites in vivo with the crystal structure.	Suzuki M, Baskin D, Hood L, Loeb LA	1996
DNA polymerase delta isolated from Schizosaccharomyces pombe contains five subunits.	Zuo S, Gibbs E, Kelman Z, Wang TS, O'Donnell ME, MacNeill SA, Hurwitz J	1997
Polkappa protects mammalian cells against the lethal and mutagenic effects of benzo[a]pyrene.	Ogi T, Shinkai Y, Tanaka K, Ohmori H	2002
A specific subdomain in phi29 DNA polymerase confers both processivity and strand-displacement capacity.	Rodríguez I, Lázaro JM, Blanco L, Kamtekar S, Berman AJ, Wang J, Steitz TA, Salas M, de Vega M	2005
Error-prone replication of repeated DNA sequences by T7 DNA polymerase in the absence of its processivity subunit.	Kunkel TA, Patel SS, Johnson KA	1994
Phosphorylation of a high molecular weight DNA polymerase alpha.	Donaldson RW, Gerner EW	1987
A defective phage system reveals bacteriophage T4 replication origins that coincide with recombination hot spots.	Kreuzer KN, Alberts BM	1985
Comparison of nucleotide interactions in water, proteins, and vacuum: model for DNA polymerase fidelity.	Petruska J, Sowers LC, Goodman MF	1986
Interaction of human apurinic endonuclease and DNA polymerase beta in the base excision repair pathway.	Bennett RA, Wilson DM, Wong D, Demple B	1997
A single residue in DNA polymerases of the Escherichia coli DNA polymerase I family is critical for distinguishing between deoxy- and dideoxyribonucleotides.	Tabor S, Richardson CC	1995
Incorrect nucleotide insertion at the active site of a G:A mismatch catalyzed by DNA polymerase beta.	Lin P, Batra VK, Pedersen LC, Beard WA, Wilson SH, Pedersen LG	2008
2-Aminopurine-induced mutagenesis in T4 bacteriophage: a model relating mutation frequency to 2-aminopurine incorporation in DNA.	Goodman MF, Hopkins R, Gore WC	1977
Human immunodeficiency virus type 1 reverse transcriptase: spatial and temporal relationship between the polymerase and RNase H activities.	Gopalakrishnan V, Peliska JA, Benkovic SJ	1992
Escherichia coli polymerase I can use O2-methyldeoxythymidine or O4-methyldeoxythymidine in place of deoxythymidine in primed poly(dA-dT).poly(dA-dT) synthesis.	Singer B, Sági J, Kuśmierek JT	1983
Construction and characterization of a bacteriophage T4 DNA polymerase deficient in 3'-->5' exonuclease activity.	Frey MW, Nossal NG, Capson TL, Benkovic SJ	1993
A structural rationale for stalling of a replicative DNA polymerase at the most common oxidative thymine lesion, thymine glycol.	Aller P, Rould MA, Hogg M, Wallace SS, Doublié S	2007
Conformational changes induced in herpes simplex virus DNA polymerase upon DNA binding.	Weisshart K, Kuo AA, Painter GR, Wright LL, Furman PA, Coen DM	1993
Highly mutagenic replication by DNA polymerase V (UmuC) provides a mechanistic basis for SOS untargeted mutagenesis.	Maor-Shoshani A, Reuven NB, Tomer G, Livneh Z	2000
Purification of DNA polymerase II stimulatory factor I, a yeast single-stranded DNA-binding protein.	Brown WC, Smiley JK, Campbell JL	1990
Frequent deletions and down-regulation of micro- RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia.	Calin GA, Dumitru CD, Shimizu M, Bichi R, Zupo S, Noch E, Aldler H, Rattan S, Keating M, Rai K, Rassenti L, Kipps T, Negrini M, Bullrich F, Croce CM	2002
Oxidation state of the XRCC1 N-terminal domain regulates DNA polymerase beta binding affinity.	Cuneo MJ, London RE	2010
RNA-primed DNA synthesis: specific catalysis by HeLa cell DNA polymerase alpha.	Spadari S, Weissbach A	1975
Homology between DNA polymerases of poxviruses, herpesviruses, and adenoviruses: nucleotide sequence of the vaccinia virus DNA polymerase gene.	Earl PL, Jones EV, Moss B	1986
Evidence that a high molecular weight replicative DNA polymerase is conserved during evolution.	Hübscher U, Spanos A, Albert W, Grummt F, Banks GR	1981
Isolation of an intact DNA polymerase-primase from embryos of Drosophila melanogaster.	Kaguni LS, Rossignol JM, Conaway RC, Lehman IR	1983
Mutagenesis during in vitro DNA synthesis.	Weymouth LA, Loeb LA	1978
Role of human DNA polymerase kappa as an extender in translesion synthesis.	Haracska L, Prakash L, Prakash S	2002
Werner syndrome protein interacts functionally with translesion DNA polymerases.	Kamath-Loeb AS, Lan L, Nakajima S, Yasui A, Loeb LA	2007
Identification of 5'-deoxyribose phosphate lyase activity in human DNA polymerase gamma and its role in mitochondrial base excision repair in vitro.	Longley MJ, Prasad R, Srivastava DK, Wilson SH, Copeland WC	1998
Phage phi29 and Nf terminal protein-priming domain specifies the internal template nucleotide to initiate DNA replication.	Longás E, Villar L, Lázaro JM, de Vega M, Salas M	2008
Werner protein recruits DNA polymerase delta to the nucleolus.	Szekely AM, Chen YH, Zhang C, Oshima J, Weissman SM	2000
Purification in a functional form of the terminal protein of Bacillus subtilis phage phi 29.	Prieto I, Lázaro JM, García JA, Hermoso JM, Salas M	1984
Terminal protein-primed DNA amplification.	Blanco L, Lázaro JM, de Vega M, Bonnin A, Salas M	1994
Exonucleolytic proofreading by calf thymus DNA polymerase delta.	Kunkel TA, Sabatino RD, Bambara RA	1987
Structural analysis of the inactive state of the Escherichia coli DNA polymerase clamp-loader complex.	Kazmirski SL, Podobnik M, Weitze TF, O'Donnell ME, Kuriyan J	2004
A separate editing exonuclease for DNA replication: the epsilon subunit of Escherichia coli DNA polymerase III holoenzyme.	Scheuermann RH, Echols H	1984
DNA polymerization in the absence of exonucleolytic proofreading: in vivo and in vitro studies.	Reha-Krantz LJ, Stocki S, Nonay RL, Dimayuga E, Goodrich LD, Konigsberg WH, Spicer EK	1991
A unique loop in the DNA-binding crevice of bacteriophage T7 DNA polymerase influences primer utilization.	Chowdhury K, Tabor S, Richardson CC	2000
De novo synthesis of budding yeast DNA polymerase alpha and POL1 transcription at the G1/S boundary are not required for entrance into S phase.	Muzi Falconi M, Piseri A, Ferrari M, Lucchini G, Plevani P, Foiani M	1993
The kinetoplast structure-specific endonuclease I is related to the 5' exo/endonuclease domain of bacterial DNA polymerase I and colocalizes with the kinetoplast topoisomerase II and DNA polymerase beta during replication.	Engel ML, Ray DS	1999
The 3'-->5' exonuclease of DNA polymerase delta can substitute for the 5' flap endonuclease Rad27/Fen1 in processing Okazaki fragments and preventing genome instability.	Jin YH, Obert R, Burgers PM, Kunkel TA, Resnick MA, Gordenin DA	2001
Evidence for a role for DNA polymerase beta in mammalian meiosis.	Plug AW, Clairmont CA, Sapi E, Ashley T, Sweasy JB	1997
Resolution of the diadenosine 5',5"'-P1,P4-tetraphosphate binding subunit from a multiprotein form of HeLa cell DNA polymerase alpha.	Baril E, Bonin P, Burstein D, Mara K, Zamecnik P	1983
Escherichia coli DNA polymerase II catalyzes chromosomal and episomal DNA synthesis in vivo.	Rangarajan S, Gudmundsson G, Qiu Z, Foster PL, Goodman MF	1997
Construction of a plasmid that overproduces the large proteolytic fragment (Klenow fragment) of DNA polymerase I of Escherichia coli.	Joyce CM, Grindley ND	1983
The cellular DNA polymerase alpha-primase is required for papillomavirus DNA replication and associates with the viral E1 helicase.	Park P, Copeland W, Yang L, Wang T, Botchan MR, Mohr IJ	1994
Structure of PolC reveals unique DNA binding and fidelity determinants.	Evans RJ, Davies DR, Bullard JM, Christensen J, Green LS, Guiles JW, Pata JD, Ribble WK, Janjic N, Jarvis TC	2008
Design and synthesis of a 3'-O-allyl photocleavable fluorescent nucleotide as a reversible terminator for DNA sequencing by synthesis.	Ruparel H, Bi L, Li Z, Bai X, Kim DH, Turro NJ, Ju J	2005
The Tyr-265-to-Cys mutator mutant of DNA polymerase beta induces a mutator phenotype in mouse LN12 cells.	Clairmont CA, Narayanan L, Sun KW, Glazer PM, Sweasy JB	1999
Cloning and expression of T4 DNA polymerase.	Lin TC, Rush J, Spicer EK, Konigsberg WH	1987
Human and mouse homologs of Escherichia coli DinB (DNA polymerase IV), members of the UmuC/DinB superfamily.	Gerlach VL, Aravind L, Gotway G, Schultz RA, Koonin EV, Friedberg EC	1999
Structure of the HIV-1 integrase catalytic domain complexed with an inhibitor: a platform for antiviral drug design.	Goldgur Y, Craigie R, Cohen GH, Fujiwara T, Yoshinaga T, Fujishita T, Sugimoto H, Endo T, Murai H, Davies DR	1999
Orchestration of cooperative events in DNA synthesis and repair mechanism unraveled by transition path sampling of DNA polymerase beta's closing.	Radhakrishnan R, Schlick T	2004
Biochemical evidence for the requirement of Hoogsteen base pairing for replication by human DNA polymerase iota.	Johnson RE, Prakash L, Prakash S	2005
Identification of the epsilon-subunit of Escherichia coli DNA polymerase III holoenzyme as the dnaQ gene product: a fidelity subunit for DNA replication.	Scheuermann R, Tam S, Burgers PM, Lu C, Echols H	1983
Replication protein A and proliferating cell nuclear antigen coordinate DNA polymerase selection in 8-oxo-guanine repair.	Maga G, Crespan E, Wimmer U, van Loon B, Amoroso A, Mondello C, Belgiovine C, Ferrari E, Locatelli GA, Villani G, Hübscher U	2008
Limited terminal transferase in human DNA polymerase mu defines the required balance between accuracy and efficiency in NHEJ.	Andrade P, Martín MJ, Juárez R, López de Saro F, Blanco L	2009
DNA polymerase accuracy and spontaneous mutation rates: frequencies of purine.purine, purine.pyrimidine, and pyrimidine.pyrimidine mismatches during DNA replication.	Fersht AR, Knill-Jones JW	1981
In vitro evolution of terminal protein-containing genomes.	Esteban JA, Blanco L, Villar L, Salas M	1997
A DNA polymerase alpha pause site is a hot spot for nucleotide misinsertion.	Fry M, Loeb LA	1992
The carboxyl terminus of the bacteriophage T4 DNA polymerase is required for holoenzyme complex formation.	Berdis AJ, Soumillion P, Benkovic SJ	1996
Detection of specific polymerase chain reaction product by utilizing the 5'----3' exonuclease activity of Thermus aquaticus DNA polymerase.	Holland PM, Abramson RD, Watson R, Gelfand DH	1991
PCNA binding domains in all three subunits of yeast DNA polymerase {delta} modulate its function in DNA replication.	Acharya N, Klassen R, Johnson RE, Prakash L, Prakash S	2011
Crystal structure of human immunodeficiency virus type 1 reverse transcriptase complexed with double-stranded DNA at 3.0 A resolution shows bent DNA.	Jacobo-Molina A, Ding J, Nanni RG, Clark AD, Lu X, Tantillo C, Williams RL, Kamer G, Ferris AL, Clark PK	1993
Kinetic measurement of 2-aminopurine X cytosine and 2-aminopurine X thymine base pairs as a test of DNA polymerase fidelity mechanisms.	Watanabe SM, Goodman MF	1982
Correlations between the activities of DNA polymerase alpha and the glucocorticoid receptor.	Schmidt TJ, Bollum FJ, Litwack G	1982
Proofreading by DNA polymerase III of Escherichia coli depends on cooperative interaction of the polymerase and exonuclease subunits.	Maki H, Kornberg A	1987
Abundant ribonucleotide incorporation into DNA by yeast replicative polymerases.	Nick McElhinny SA, Watts BE, Kumar D, Watt DL, Lundström EB, Burgers PM, Johansson E, Chabes A, Kunkel TA	2010
Demonstration of a stimulatory protein for virus-specified DNA polymerase in phorbol ester-treated Epstein-Barr virus-carrying cells.	Chiou JF, Li JK, Cheng YC	1985
Yeast Rev1 protein promotes complex formation of DNA polymerase zeta with Pol32 subunit of DNA polymerase delta.	Acharya N, Johnson RE, Pagès V, Prakash L, Prakash S	2009
Cocrystal structure of an editing complex of Klenow fragment with DNA.	Freemont PS, Friedman JM, Beese LS, Sanderson MR, Steitz TA	1988
DNA conformational changes at the primer-template junction regulate the fidelity of replication by DNA polymerase.	Datta K, Johnson NP, von Hippel PH	2010
Identification of a higher molecular weight DNA polymerase alpha catalytic polypeptide in monkey cells by monoclonal antibody.	Karawya E, Swack J, Albert W, Fedorko J, Minna JD, Wilson SH	1984
A cancer-associated DNA polymerase delta variant modeled in yeast causes a catastrophic increase in genomic instability.	Daee DL, Mertz TM, Shcherbakova PV	2010
Archaeal eukaryote-like Orc1/Cdc6 initiators physically interact with DNA polymerase B1 and regulate its functions.	Zhang L, Zhang L, Liu Y, Yang S, Gao C, Gong H, Feng Y, He ZG	2009
Efficient and accurate bypass of N2-(1-carboxyethyl)-2'-deoxyguanosine by DinB DNA polymerase in vitro and in vivo.	Yuan B, Cao H, Jiang Y, Hong H, Wang Y	2008
Conformational transitions in DNA polymerase I revealed by single-molecule FRET.	Santoso Y, Joyce CM, Potapova O, Le Reste L, Hohlbein J, Torella JP, Grindley ND, Kapanidis AN	2010
A heterodimeric DNA polymerase: evidence that members of Euryarchaeota possess a distinct DNA polymerase.	Cann IK, Komori K, Toh H, Kanai S, Ishino Y	1998
Enzymatic joining of DNA strands: a novel reaction of diphosphopyridine nucleotide.	Zimmerman SB, Little JW, Oshinsky CK, Gellert M	1967
Separation of the adenovirus terminal protein precursor from its associated DNA polymerase: role of both proteins in the initiation of adenovirus DNA replication.	Lichy JH, Field J, Horwitz MS, Hurwitz J	1982
A type IB topoisomerase with DNA repair activities.	Belova GI, Prasad R, Kozyavkin SA, Lake JA, Wilson SH, Slesarev AI	2001
Comparative properties of RNA and DNA templates for the DNA polymerase of Rous sarcoma virus.	Duesberg P, Helm KV, Canaani E	1971
DNA polymerase alpha mutants from a Drosophila melanogaster cell line.	Sugino A, Nakayama K	1980
Terminal protein-primed amplification of heterologous DNA with a minimal replication system based on phage {Phi}29.	Mencía M, Gella P, Camacho A, de Vega M, Salas M	2011
DNA endonucleases associated with the avian myeloblastosis virus DNA polymerase.	Samuel KP, Papas TS, Chirikjian JG	1979
Mechanism of nucleotide incorporation opposite a thymine-thymine dimer by yeast DNA polymerase eta.	Washington MT, Prakash L, Prakash S	2003
Replication of duplex DNA by bacteriophage T7 DNA polymerase and gene 4 protein is accompanied by hydrolysis of nucleoside 5'-triphosphates.	Kolodner R, Richardson CC	1977
ENZYMATIC SYNTHESIS OF DEOXYRIBONUCLEIC ACID. III. THE INCORPORATION OF PYRIMIDINE AND PURINE ANALOGUES INTO DEOXYRIBONUCLEIC ACID.	Bessman MJ, Lehman IR, Adler J, Zimmerman SB, Simms ES, Kornberg A	1958
Mechanism of DNA polymerase II-mediated frameshift mutagenesis.	Becherel OJ, Fuchs RP	2001
ENZYMATIC SYNTHESIS OF DEOXYRIBONUCLEIC ACID. IV. LINKAGE OF SINGLE DEOXYNUCLEOTIDES TO THE DEOXYNUCLEOSIDE ENDS OF DEOXYRIBONUCLEIC ACID.	Adler J, Lehman IR, Bessman MJ, Simms ES, Kornberg A	1958
Genetic analysis of the interaction between bacteriophage T7 DNA polymerase and Escherichia coli thioredoxin.	Himawan JS, Richardson CC	1992
Targeting of DNA polymerase to the adenovirus origin of DNA replication by interaction with nuclear factor I.	Armentero MT, Horwitz M, Mermod N	1994
Ubiquitinated proliferating cell nuclear antigen activates translesion DNA polymerases eta and REV1.	Garg P, Burgers PM	2005
A 5' to 3' exonuclease functionally interacts with calf DNA polymerase epsilon.	Siegal G, Turchi JJ, Myers TW, Bambara RA	1992
DPB2, the gene encoding DNA polymerase II subunit B, is required for chromosome replication in Saccharomyces cerevisiae.	Araki H, Hamatake RK, Johnston LH, Sugino A	1991
3'-Azido-3'-deoxythymidine drug resistance mutations in HIV-1 reverse transcriptase can induce long range conformational changes.	Ren J, Esnouf RM, Hopkins AL, Jones EY, Kirby I, Keeling J, Ross CK, Larder BA, Stuart DI, Stammers DK	1998
Effect of 3' flanking neighbors on kinetics of pairing of dCTP or dTTP opposite O6-methylguanine in a defined primed oligonucleotide when Escherichia coli DNA polymerase I is used.	Singer B, Chavez F, Goodman MF, Essigmann JM, Dosanjh MK	1989
Directed evolution of polymerase function by compartmentalized self-replication.	Ghadessy FJ, Ong JL, Holliger P	2001
A coupled complex of T4 DNA replication helicase (gp41) and polymerase (gp43) can perform rapid and processive DNA strand-displacement synthesis.	Dong F, Weitzel SE, von Hippel PH	1996
Purification and characterization of the DNA polymerase of human breast cancer particles.	Ohno T, Sweet RW, Dejak D, Spiegelman S	1977
Intracellular localization of mouse DNA polymerase-alpha.	Herrick G, Spear BB, Veomett G	1976
Regulation of polymerase exchange between Poleta and Poldelta by monoubiquitination of PCNA and the movement of DNA polymerase holoenzyme.	Zhuang Z, Johnson RE, Haracska L, Prakash L, Prakash S, Benkovic SJ	2008
Single-strand binding protein enhances fidelity of DNA synthesis in vitro.	Kunkel TA, Meyer RR, Loeb LA	1979
A tumor necrosis factor alpha- and interleukin 6-inducible protein that interacts with the small subunit of DNA polymerase delta and proliferating cell nuclear antigen.	He H, Tan CK, Downey KM, So AG	2001
Identification of a transient excision intermediate at the crossroads between DNA polymerase extension and proofreading pathways.	Baker RP, Reha-Krantz LJ	1998
Protein affinity chromatography with purified yeast DNA polymerase alpha detects proteins that bind to DNA polymerase.	Miles J, Formosa T	1992
Mismatch-specific 3'----5' exonuclease associated with the mitochondrial DNA polymerase from Drosophila embryos.	Kaguni LS, Olson MW	1989
Hydrogen bonding revisited: geometric selection as a principal determinant of DNA replication fidelity.	Goodman MF	1997
Rapid assembly of the bacteriophage T4 core replication complex on a linear primer/template construct.	Kaboord BF, Benkovic SJ	1993
Interaction of the beta sliding clamp with MutS, ligase, and DNA polymerase I.	López de Saro FJ, O'Donnell ME	2001
Analysis of mutations at positions 115 and 116 in the dNTP binding site of HIV-1 reverse transcriptase.	Boyer PL, Sarafianos SG, Arnold E, Hughes SH	2000
Activity of the purified mutagenesis proteins UmuC, UmuD', and RecA in replicative bypass of an abasic DNA lesion by DNA polymerase III.	Rajagopalan M, Lu C, Woodgate R, O'Donnell ME, Goodman MF, Echols H	1992
Pentaribonucleotides of mixed sequence are synthesized and efficiently prime de novo DNA chain starts in the T4 bacteriophage DNA replication system.	Liu CC, Alberts BM	1980
Discrimination against purine-pyrimidine mispairs in the polymerase active site of DNA polymerase I: a structural explanation.	Minnick DT, Liu L, Grindley ND, Kunkel TA, Joyce CM	2002
Detection and characterization of mammalian DNA polymerase beta mutants by functional complementation in Escherichia coli.	Sweasy JB, Loeb LA	1993
Mammalian mutator mutant with an aphidicolin-resistant DNA polymerase alpha.	Liu PK, Chang CC, Trosko JE, Dube DK, Martin GM, Loeb LA	1983
Promoters selected from random DNA sequences.	Horwitz MS, Loeb LA	1986
Rearrangements of DNA mediated by terminal transferase.	Kunkel TA, Gopinathan KP, Dube DK, Snow ET, Loeb LA	1986
Cyclin A activates the DNA polymerase delta -dependent elongation machinery in vitro: A parvovirus DNA replication model.	Bashir T, Horlein R, Rommelaere J, Willwand K	2000
Fialuridine and its metabolites inhibit DNA polymerase gamma at sites of multiple adjacent analog incorporation, decrease mtDNA abundance, and cause mitochondrial structural defects in cultured hepatoblasts.	Lewis W, Levine ES, Griniuviene B, Tankersley KO, Colacino JM, Sommadossi JP, Watanabe KA, Perrino FW	1996
Transposon Tn5 excision in yeast: influence of DNA polymerases alpha, delta, and epsilon and repair genes.	Gordenin DA, Malkova AL, Peterzen A, Kulikov VN, Pavlov YI, Perkins E, Resnick MA	1992
Polymerase recognition of synthetic oligodeoxyribonucleotides incorporating degenerate pyrimidine and purine bases.	Hill F, Loakes D, Brown DM	1998
Replication of UV-irradiated single-stranded DNA by DNA polymerase III holoenzyme of Escherichia coli: evidence for bypass of pyrimidine photodimers.	Livneh Z	1986
Probable involvement of a glycoconjugate in IMR-32 DNA synthesis: decrease of DNA polymerase alpha 2 activity after tunicamycin treatment.	Bhattacharya P, Basu S	1982
DNA polymerase delta from embryos of Drosophila melanogaster.	Chiang CS, Mitsis PG, Lehman IR	1993
A cryptic proofreading 3'----5' exonuclease associated with the polymerase subunit of the DNA polymerase-primase from Drosophila melanogaster.	Cotterill SM, Reyland ME, Loeb LA, Lehman IR	1987
Mechanism of elongation of primed DNA by DNA polymerase delta, proliferating cell nuclear antigen, and activator 1.	Lee SH, Hurwitz J	1990
Crystal structure of a benzo[a]pyrene diol epoxide adduct in a ternary complex with a DNA polymerase.	Ling H, Sayer JM, Plosky BS, Yagi H, Boudsocq F, Woodgate R, Jerina DM, Yang WW	2004
Structure of a small-molecule inhibitor of a DNA polymerase sliding clamp.	Georgescu RE, Yurieva O, Kim SS, Kuriyan J, Kong XP, O'Donnell ME	2008
Functional roles of DNA polymerases beta and gamma.	Hübscher U, Kuenzle CC, Spadari S	1979
Crystal structure of DNA-bound Co(III) bleomycin B2: Insights on intercalation and minor groove binding.	Goodwin KD, Lewis MA, Long EC, Georgiadis MM	2008
Absolute configuration of the diastereomers of adenosine 5'-O-(1-thiotriphosphate): consequences for the stereochemistry of polymerization by DNA-dependent RNA polymerase from Escherichia coli.	Burgers PM, Eckstein F	1978
Requirement of proliferating cell nuclear antigen in RAD6-dependent postreplicational DNA repair.	Torres-Ramos CA, Yoder BL, Burgers PM, Prakash S, Prakash L	1996
What a difference a decade makes: insights into translesion DNA synthesis.	Yang WW, Woodgate R	2007
Multiple point mutations in a shuttle vector propagated in human cells: evidence for an error-prone DNA polymerase activity.	Seidman MM, Bredberg A, Seetharam S, Kraemer KH	1987
Specificity and efficiency of editing of mismatches involved in the formation of base-substitution mutations by the 3'----5' exonuclease activity of phage T4 DNA polymerase.	Sinha NK	1987
A single side chain prevents Escherichia coli DNA polymerase I (Klenow fragment) from incorporating ribonucleotides.	Astatke M, Ng K, Grindley ND, Joyce CM	1998
Expression of DNA polymerase {beta} cancer-associated variants in mouse cells results in cellular transformation.	Sweasy JB, Lang T, Starcevic D, Sun KW, Lai CC, Dimaio D, Dalal S	2005
Reduced in vivo mutagenesis by mutant herpes simplex DNA polymerase involves improved nucleotide selection.	Hall JD, Furman PA, St Clair MH, Knopf CW	1985
Mammalian DNA polymerase alpha holoenzymes with possible functions at the leading and lagging strand of the replication fork.	Ottiger HP, Hübscher U	1984
Synthesis of DNA containing the simian virus 40 origin of replication by the combined action of DNA polymerases alpha and delta.	Lee SH, Eki T, Hurwitz J	1989
Incorporation into DNA of the base analog 2-aminopurine by the Epstein-Barr virus-induced DNA polymerase in vivo and in vitro.	Grossberger D, Clough W	1981
The enzymological basis for resistance of herpesvirus DNA polymerase mutants to acyclovir: relationship to the structure of alpha-like DNA polymerases.	Huang L, Ishii KK, Zuccola H, Gehring AM, Hwang CB, Hogle J, Coen DM	1999
The beta subunit sliding DNA clamp is responsible for unassisted mutagenic translesion replication by DNA polymerase III holoenzyme.	Tomer G, Reuven NB, Livneh Z	1998
DNA nick processing by exonuclease and polymerase activities of bacteriophage T4 DNA polymerase accounts for acridine-induced mutation specificities in T4.	Kaiser VL, Ripley LS	1995
Creating a dynamic picture of the sliding clamp during T4 DNA polymerase holoenzyme assembly by using fluorescence resonance energy transfer.	Trakselis MA, Alley SC, Abel-Santos E, Benkovic SJ	2001
Structure of the binding site for nonnucleoside inhibitors of the reverse transcriptase of human immunodeficiency virus type 1.	Smerdon SJ, Jäger J, Wang J, Kohlstaedt LA, Chirino AJ, Friedman JM, Rice PA, Steitz TA	1994
The replicative DNA polymerase of herpes simplex virus 1 exhibits apurinic/apyrimidinic and 5'-deoxyribose phosphate lyase activities.	Bogani F, Boehmer PE	2008
Use of DNA polymerase I primed by a synthetic oligonucleotide to determine a nucleotide sequence in phage fl DNA.	Sanger F, Donelson JE, Coulson AR, Kössel H, Fischer D	1973
Single molecule measurement of the "speed limit" of DNA polymerase.	Schwartz JJ, Quake SR	2009
DNA polymerase active site is highly mutable: evolutionary consequences.	Patel PH, Loeb LA	2000
An antiviral target on reverse transcriptase of human immunodeficiency virus type 1 revealed by tetrahydroimidazo-[4,5,1-jk] [1,4]benzodiazepin-2 (1H)-one and -thione derivatives.	Debyser Z, Pauwels R, Andries K, Desmyter J, Kukla M, Janssen PA, De Clercq E	1991
Construction of biologically functional bacterial plasmids in vitro.	Cohen SN, Chang AC, Boyer HW, Helling RB	1973
Structure of HIV-2 reverse transcriptase at 2.35-A resolution and the mechanism of resistance to non-nucleoside inhibitors.	Ren J, Bird LE, Chamberlain PP, Stewart-Jones GB, Stuart DI, Stammers DK	2002
The thioredoxin binding domain of bacteriophage T7 DNA polymerase confers processivity on Escherichia coli DNA polymerase I.	Bedford E, Tabor S, Richardson CC	1997
Participation of mouse DNA polymerase iota in strand-biased mutagenic bypass of UV photoproducts and suppression of skin cancer.	Dumstorf CA, Clark AB, Lin Q, Kissling GE, Yuan T, Kucherlapati R, McGregor WG, Kunkel TA	2006
Affinity purification of bacteriophage T4 proteins essential for DNA replication and genetic recombination.	Formosa T, Burke RL, Alberts BM	1983
Bacterial and phage mutations that reveal helix-unwinding activities required for bacteriophage T4 DNA replication.	Gauss P, Doherty DH, Gold L	1983
Probing the active site tightness of DNA polymerase in subangstrom increments.	Kim TW, Delaney JC, Essigmann JM, Kool ET	2005
Accessory proteins for DNA polymerase alpha activity with single-strand DNA templates.	Lamothe P, Baril B, Chi A, Lee L, Baril E	1981
A DNA primase activity associated with DNA polymerase alpha from Drosophila melanogaster embryos.	Conaway RC, Lehman IR	1982
Diadenosine 5',5'''-P1,P4-tetraphosphate, a ligand of the 57-kilodalton subunit of DNA polymerase alpha.	Grummt F, Waltl G, Jantzen HM, Hamprecht K, Huebscher U, Kuenzle CC	1979
Stationary-phase mutation in the bacterial chromosome: recombination protein and DNA polymerase IV dependence.	Bull HJ, Lombardo MJ, Rosenberg SM	2001
Crystal structure of Taq DNA polymerase in complex with an inhibitory Fab: the Fab is directed against an intermediate in the helix-coil dynamics of the enzyme.	Murali R, Sharkey DJ, Daiss JL, Murthy HM	1998
Two distinct modes of RecA action are required for DNA polymerase V-catalyzed translesion synthesis.	Pham P, Seitz EM, Saveliev S, Shen X, Woodgate R, Cox MM, Goodman MF	2002
Quantitative measurement of translesion replication in human cells: evidence for bypass of abasic sites by a replicative DNA polymerase.	Avkin S, Adar S, Blander G, Livneh Z	2002
Molecular analysis of mutations in DNA polymerase eta in xeroderma pigmentosum-variant patients.	Broughton BC, Cordonnier AM, Kleijer WJ, Jaspers NG, Fawcett H, Raams A, Garritsen VH, Stary A, Avril MF, Boudsocq F, Masutani C, Hanaoka F, Fuchs RP, Sarasin A, Lehmann AR	2002
Long-term inhibition of human T-lymphotropic virus type III/lymphadenopathy-associated virus (human immunodeficiency virus) DNA synthesis and RNA expression in T cells protected by 2',3'-dideoxynucleosides in vitro.	Mitsuya H, Jarrett RF, Matsukura M, di Marzo Veronese F, DeVico AL, Sarngadharan MG, Johns DG, Reitz MS, Broder S	1987
Broad spectrum of in vivo forward mutations, hypermutations, and mutational hotspots in a retroviral shuttle vector after a single replication cycle: deletions and deletions with insertions.	Pathak VK, Temin HM	1990
The C-terminal region of Schizosaccaromyces pombe proliferating cell nuclear antigen is essential for DNA polymerase activity.	Kelman Z, Zuo S, Arroyo MP, Wang TS, Hurwitz J	1999
DNA sequencing with chain-terminating inhibitors.	Sanger F, Nicklen S, Coulson AR	1977
Copy-choice recombination mediated by DNA polymerase III holoenzyme from Escherichia coli.	Canceill D, Ehrlich SD	1996
Interaction of herpes simplex virus 1 origin-binding protein with DNA polymerase alpha.	Lee SS, Dong Q, Wang TS, Lehman IR	1995
DNA polymerase of bacteriophage T4 is an autogenous translational repressor.	Andrake M, Guild N, Hsu T, Gold L, Tuerk C, Karam J	1988
Targeted gene evolution in Escherichia coli using a highly error-prone DNA polymerase I.	Camps M, Naukkarinen J, Johnson BP, Loeb LA	2003
Functions of replication factor C and proliferating-cell nuclear antigen: functional similarity of DNA polymerase accessory proteins from human cells and bacteriophage T4.	Tsurimoto T, Stillman B	1990
Okazaki fragment processing: modulation of the strand displacement activity of DNA polymerase delta by the concerted action of replication protein A, proliferating cell nuclear antigen, and flap endonuclease-1.	Maga G, Villani G, Tillement V, Stucki M, Locatelli GA, Frouin I, Spadari S, Hübscher U	2001
Specific inhibition of herpes simplex virus DNA polymerase by helical peptides corresponding to the subunit interface.	Digard P, Williams KP, Hensley P, Brooks IS, Dahl CE, Coen DM	1995
High incidence of epithelial cancers in mice deficient for DNA polymerase delta proofreading.	Goldsby RE, Hays LE, Chen X, Olmsted EA, Slayton WB, Spangrude GJ, Preston BD	2002
An 8-oxo-guanine repair pathway coordinated by MUTYH glycosylase and DNA polymerase lambda.	van Loon B, Hübscher U	2009
Cdk-interacting protein 1 directly binds with proliferating cell nuclear antigen and inhibits DNA replication catalyzed by the DNA polymerase delta holoenzyme.	Flores-Rozas H, Kelman Z, Dean FB, Pan ZQ, Harper JW, Elledge SJ, O'Donnell ME, Hurwitz J	1994
Human immunodeficiency virus reverse transcriptase substitutes for DNA polymerase I in Escherichia coli.	Kim B, Loeb LA	1995
Recombination hotspots in bacteriophage T4 are dependent on replication origins.	Yap WY, Kreuzer KN	1991
Structure-based design of Taq DNA polymerases with improved properties of dideoxynucleotide incorporation.	Li Y, Mitaxov V, Waksman G	1999
Stimulation of human neuroblastoma DNA polymerase alpha and primase activities by a protein factor isolated from rat liver chromatin.	Takada S, Torres-Rosado A, Ray S, Basu S	1986
Inhibition of human neuroblastoma DNA polymerase activities by plant lectins and toxins.	Bhattacharya P, Simet I, Basu S	1979
Purification and DNA synthesis in cell-free extracts: properties of DNA polymerase II.	Kornberg T, Gefter ML	1971
DNA polymerase delta is required for base excision repair of DNA methylation damage in Saccharomyces cerevisiae.	Blank A, Kim B, Loeb LA	1994
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Escherichia coli DnaX product, the tau subunit of DNA polymerase III, is a multifunctional protein with single-stranded DNA-dependent ATPase activity.	Lee SH, Walker JR	1987
The dynamic processivity of the T4 DNA polymerase during replication.	Yang J, Zhuang Z, Roccasecca RM, Trakselis MA, Benkovic SJ	2004
Generation of single-stranded DNA by the polymerase chain reaction and its application to direct sequencing of the HLA-DQA locus.	Gyllensten UB, Erlich HA	1988
Priming of DNA synthesis by diadenosine 5',5"'-P1,P4-tetraphosphate with a double-stranded octadecamer as a template and DNA polymerase alpha.	Zamecnik PC, Rapaport E, Baril EF	1982
Removal of polymerase-produced mutant sequences from PCR products.	Smith J, Modrich P	1997
Proliferating cell nuclear antigen promotes DNA synthesis past template lesions by mammalian DNA polymerase delta.	Mozzherin DJ, Shibutani S, Tan CK, Downey KM, Fisher PA	1997
Effect of manganese ions on the incorporation of dideoxynucleotides by bacteriophage T7 DNA polymerase and Escherichia coli DNA polymerase I.	Tabor S, Richardson CC	1989
Escherichia coli thioredoxin: a subunit of bacteriophage T7 DNA polymerase.	Mark DF, Richardson CC	1976
In search of a mutational hotspot.	Hatahet Z, Zhou M, Reha-Krantz LJ, Morrical SW, Wallace SS	1998
Retention of replication fidelity by a DNA polymerase functioning in a distantly related environment.	Dressman HK, Wang CC, Karam JD, Drake JW	1997
Heat mutagenesis in bacteriophage T4: the transversion pathway.	Bingham PM, Baltz RH, Ripley LS, Drake JW	1976
Distinct mechanisms of cis-syn thymine dimer bypass by Dpo4 and DNA polymerase eta.	Johnson RE, Prakash L, Prakash S	2005
Bridging the gap: a family of novel DNA polymerases that replicate faulty DNA.	Johnson RE, Washington MT, Prakash S, Prakash L	1999
Mechanism of DNA polymerase I: exonuclease/polymerase activity switch and DNA sequence dependence of pyrophosphorolysis and misincorporation reactions.	Mizrahi V, Benkovic P, Benkovic SJ	1986
A DNA-binding protein induced by bacteriophage T7.	Reuben RC, Gefter ML	1973
Improvement of phi29 DNA polymerase amplification performance by fusion of DNA binding motifs.	de Vega M, Lázaro JM, Mencía M, Blanco L, Salas M	2010
DNA polymerase eta lacking the ubiquitin-binding domain promotes replicative lesion bypass in humans cells.	Acharya N, Yoon JH, Hurwitz J, Prakash L, Prakash S	2010
PCR amplification of up to 35-kb DNA with high fidelity and high yield from lambda bacteriophage templates.	Barnes WM	1994
Mechanism of carcinogenesis by RNA tumor viruses. 3. Formation of RNA, DNA complex and duplex DNA molecules by the DNA polymerase (s) of avian myeloblastosis virus.	Fujinaga K, Parsons JT, Beard JW, Beard D, Green M	1970
Replication of phage phi 29 DNA with purified terminal protein and DNA polymerase: synthesis of full-length phi 29 DNA.	Blanco L, Salas M	1985
Initiation of phage phi 29 DNA replication in vitro: formation of a covalent complex between the terminal protein, p3, and 5'-dAMP.	Peñalva MA, Salas M	1982
Structure of DNA polymerase beta with a benzo[c]phenanthrene diol epoxide-adducted template exhibits mutagenic features.	Batra VK, Shock DD, Prasad R, Beard WA, Hou EW, Pedersen LC, Sayer JM, Yagi H, Kumar S, Jerina DM, Wilson SH	2006
High-resolution structures of HIV-1 reverse transcriptase/TMC278 complexes: strategic flexibility explains potency against resistance mutations.	Das K, Bauman JD, Clark AD, Frenkel YV, Lewi PJ, Shatkin AJ, Hughes SH, Arnold E	2008
DNA polymerase III of Escherichia coli is required for UV and ethyl methanesulfonate mutagenesis.	Hagensee ME, Timme TL, Bryan SK, Moses RE	1987
Nucleotide-dependent conformational change governs specificity and analog discrimination by HIV reverse transcriptase.	Kellinger MW, Johnson KA	2010
Synthesis of parvovirus H-1 replicative form from viral DNA by DNA polymerase gamma.	Kollek R, Goulian M	1981
DNA polymerase epsilon is required for coordinated and efficient chromosomal DNA replication in Xenopus egg extracts.	Waga S, Masuda T, Takisawa H, Sugino A	2001
Replication infidelity via a mismatch with Watson-Crick geometry.	Bebenek K, Pedersen LC, Kunkel TA	2011
Architecture of the DNA polymerase B-proliferating cell nuclear antigen (PCNA)-DNA ternary complex.	Mayanagi K, Kiyonari S, Nishida H, Saito M, Kohda D, Ishino Y, Shirai T, Morikawa K	2011
Conferring RNA polymerase activity to a DNA polymerase: a single residue in reverse transcriptase controls substrate selection.	Gao G, Orlova M, Georgiadis MM, Hendrickson WA, Goff SP	1997
DNA sequencing with Thermus aquaticus DNA polymerase and direct sequencing of polymerase chain reaction-amplified DNA.	Innis MA, Myambo KB, Gelfand DH, Brow MA	1988
Mechanism of resistance of human immunodeficiency virus type 1 to 2',3'-dideoxyinosine.	Martin JL, Wilson JE, Haynes RL, Furman PA	1993
DNA strand breaking by the hydroxyl radical is governed by the accessible surface areas of the hydrogen atoms of the DNA backbone.	Balasubramanian B, Pogozelski WK, Tullius TD	1998
Replication of bacteriophage phi 29 DNA in vitro: the roles of terminal protein and DNA polymerase.	Watabe K, Leusch M, Ito J	1984
RNA virus error catastrophe: direct molecular test by using ribavirin.	Crotty S, Cameron CE, Andino R	2001
Mutagenic DNA polymerase in human leukemic cells.	Springgate CF, Loeb LA	1973
Lamivudine (3TC) resistance in HIV-1 reverse transcriptase involves steric hindrance with beta-branched amino acids.	Sarafianos SG, Das K, Clark AD, Ding J, Boyer PL, Hughes SH, Arnold E	1999
Unblocking of chain-terminated primer by HIV-1 reverse transcriptase through a nucleotide-dependent mechanism.	Meyer PR, Matsuura SE, So AG, Scott WA	1998
The ATF/CREB transcription factor-binding site in the polymerase beta promoter mediates the positive effect of N-methyl-N'-nitro-N-nitrosoguanidine on transcription.	Kedar PS, Widen SG, Englander EW, Fornace AJ, Wilson SH	1991
Frameshift mutations produced by proflavin in bacteriophage T4: specificity within a hotspot.	Ripley LS, Clark A	1986
Conformational dynamics of bacteriophage T7 DNA polymerase and its processivity factor, Escherichia coli thioredoxin.	Akabayov B, Akabayov SR, Lee SJ, Tabor S, Kulczyk AW, Richardson CC	2010
Primary structure of the catalytic subunit of human DNA polymerase delta and chromosomal location of the gene.	Chung DW, Zhang JA, Tan CK, Davie EW, So AG, Downey KM	1991
A DNA polymerase beta mutant from colon cancer cells induces mutations.	Lang T, Maitra M, Starcevic D, Li SX, Sweasy JB	2004
Molecular matchmaking: NNRTIs can enhance the dimerization of HIV type 1 reverse transcriptase.	Hughes SH	2001
Structural origins of the exonuclease resistance of a zwitterionic RNA.	Teplova M, Wallace ST, Tereshko V, Minasov G, Symons AM, Cook PD, Manoharan M, Egli M	1999
Mutations in the RNase H domain of HIV-1 reverse transcriptase affect the initiation of DNA synthesis and the specificity of RNase H cleavage in vivo.	Julias JG, McWilliams MJ, Sarafianos SG, Arnold E, Hughes SH	2002
Reconstruction of bacteriophage T4 DNA replication apparatus from purified components: rolling circle replication following de novo chain initiation on a single-stranded circular DNA template.	Morris CF, Sinha NK, Alberts BM	1975
In vitro DNA replication of recombinant plasmid DNAs containing the origin of progeny replicative form DNA synthesis of phage phi X174.	Zipursky SL, Reinberg D, Hurwitz J	1980
Mechanism of the idling-turnover reaction of the large (Klenow) fragment of Escherichia coli DNA polymerase I.	Mizrahi V, Benkovic PA, Benkovic SJ	1986
Crystal structure of a thermostable type B DNA polymerase from Thermococcus gorgonarius.	Hopfner KP, Eichinger A, Engh RA, Laue F, Ankenbauer W, Huber R, Angerer B	1999
Two proton transfers in the transition state for nucleotidyl transfer catalyzed by RNA- and DNA-dependent RNA and DNA polymerases.	Castro C, Smidansky ED, Maksimchuk KR, Arnold JJ, Korneeva VS, Götte M, Konigsberg WH, Cameron CE	2007
Adriamycin and daunorubicin inhibition of mutant T4 DNA polymerases.	Goodman MF, Bessman MJ, Bachur NR	1974
DNA sequence analysis with a modified bacteriophage T7 DNA polymerase.	Tabor S, Richardson CC	1987
Effect of DNA polymerase I and DNA helicase II on the turnover rate of UvrABC excision nuclease.	Husain I, Van Houten B, Thomas DC, Abdel-Monem M, Sancar A	1985
Energy analysis of chemistry for correct insertion by DNA polymerase beta.	Lin P, Pedersen LC, Batra VK, Beard WA, Wilson SH, Pedersen LG	2006
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HeLa cell DNA polymerase alpha is tightly associated with tryptophanyl-tRNA synthetase and diadenosine 5',5"'-P1,P4-tetraphosphate binding activities.	Rapaport E, Zamecnik PC, Baril EF	1981
The structural basis for the mutagenicity of O(6)-methyl-guanine lesions.	Warren JJ, Forsberg LJ, Beese LS	2006
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A new synthetic RNA-dependent DNA polymerase from human tissue culture cells (HeLa-fibroblast-synthetic oligonucleotides-template-purified enzymes).	Fridlender B, Fry M, Bolden A, Weissbach A	1972
Assembly of a functional replication complex without ATP hydrolysis: a direct interaction of bacteriophage T4 gp45 with T4 DNA polymerase.	Reddy MK, Weitzel SE, von Hippel PH	1993
Structural determinant for switching between the polymerase and exonuclease modes in the PCNA-replicative DNA polymerase complex.	Nishida H, Mayanagi K, Kiyonari S, Sato Y, Oyama T, Ishino Y, Morikawa K	2009
Multiple functions of human single-stranded-DNA binding protein in simian virus 40 DNA replication: single-strand stabilization and stimulation of DNA polymerases alpha and delta.	Kenny MK, Lee SH, Hurwitz J	1989
The human DINB1 gene encodes the DNA polymerase Poltheta.	Johnson RE, Prakash S, Prakash L	2000
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Macromolecular crowding increases binding of DNA polymerase to DNA: an adaptive effect.	Zimmerman SB, Harrison B	1987
Emergence of human immunodeficiency virus type 1 variants with resistance to multiple dideoxynucleosides in patients receiving therapy with dideoxynucleosides.	Shirasaka T, Kavlick MF, Ueno T, Gao WY, Kojima E, Alcaide ML, Chokekijchai S, Roy BM, Arnold E, Yarchoan R	1995
Separation of deoxyribo-oligonucleotidases induced by infection with bacteriophage T2.	Short EC, Koerner JF	1965
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Clusters of mutations from transient hypermutability.	Drake JW, Bebenek A, Kissling GE, Peddada S	2005
Characterization of a temperature-sensitive mutant of mouse FM3A cells defective in DNA replication.	Murakami Y, Yasuda H, Miyazawa H, Hanaoka F, Yamada M	1985
Mutator strains of Escherichia coli, mutD and dnaQ, with defective exonucleolytic editing by DNA polymerase III holoenzyme.	Echols H, Lu C, Burgers PM	1983
Linkage of polynucleotides through phosphodiester bonds by an enzyme from Escherichia coli.	Olivera BM, Lehman IR	1967
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Yeast DNA polymerase eta makes functional contacts with the DNA minor groove only at the incoming nucleoside triphosphate.	Washington MT, Wolfle WT, Spratt TE, Prakash L, Prakash S	2003
The yeast analog of mammalian cyclin/proliferating-cell nuclear antigen interacts with mammalian DNA polymerase delta.	Bauer GA, Burgers PM	1988
Exonuclease VI, a new nuclease activity associated with E. coli DNA polymerase.	Klett RP, Cerami A, Reich E	1968
The structure of unliganded reverse transcriptase from the human immunodeficiency virus type 1.	Rodgers DW, Gamblin SJ, Harris BA, Ray S, Culp JS, Hellmig B, Woolf DJ, Debouck C, Harrison SC	1995
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Characterization and purification of a phage phi 29-encoded DNA polymerase required for the initiation of replication.	Blanco L, Salas M	1984
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Effects of different DNA polymerases in ligation-mediated PCR: enhanced genomic sequencing and in vivo footprinting.	Garrity PA, Wold BJ	1992
A bacteriophage T7 RNA polymerase/promoter system for controlled exclusive expression of specific genes.	Tabor S, Richardson CC	1985
Selective elimination of the exonuclease activity of the deoxyribonucleic acid polymerase from Escherichia coli B by limited proteolysis.	Klenow H, Henningsen I	1970
DNA primase activity associated with DNA polymerase alpha from Xenopus laevis ovaries.	Shioda M, Nelson EM, Bayne ML, Benbow RM	1982
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Absence of RNase H allows replication of pBR322 in Escherichia coli mutants lacking DNA polymerase I.	Kogoma T	1984
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Decreased fidelity of DNA polymerase activity during N-2-fluorenylacetamide hepatocarcinogenesis.	Chan JY, Becker FF	1979
The accessory subunit of DNA polymerase gamma is essential for mitochondrial DNA maintenance and development in Drosophila melanogaster.	Iyengar B, Luo N, Farr CL, Kaguni LS, Campos AR	2002
Fidelity of replication of phage phi X174 DNA by DNA polymerase III holoenzyme: spontaneous mutation by misincorporation.	Fersht AR	1979
Differential inhibition of multiple forms of DNA polymerase alpha from IMR-32 human neuroblastoma cells.	Bhattacharya P, Simet I, Basu S	1981
The enzymatic termination of polydeoxynucleotides by 2',3'-dideoxyadenosine triphosphate.	Toji L, Cohen SS	1969
Enzymatic breakage and joining of deoxyribonucleic acid, I. Repair of single-strand breaks in DNA by an enzyme system from Escherichia coli infected with T4 bacteriophage.	Weiss B, Richardson CC	1967
Thioredoxin suppresses microscopic hopping of T7 DNA polymerase on duplex DNA.	Etson CM, Hamdan SM, Richardson CC, van Oijen AM	2010
Highly error-free role of DNA polymerase eta in the replicative bypass of UV-induced pyrimidine dimers in mouse and human cells.	Yoon JH, Prakash L, Prakash S	2009
DNA polymerase zeta cooperates with polymerases kappa and iota in translesion DNA synthesis across pyrimidine photodimers in cells from XPV patients.	Ziv O, Geacintov NE, Nakajima S, Yasui A, Livneh Z	2009
Cell-free synthesis of the precursor polypeptide for avian myeloblastosis virus DNA polymerase.	Paterson BM, Marciani DJ, Papas TS	1977
A unique loop in T7 DNA polymerase mediates the binding of helicase-primase, DNA binding protein, and processivity factor.	Hamdan SM, Marintcheva B, Cook TE, Lee SJ, Tabor S, Richardson CC	2005
Template-directed pausing in in vitro DNA synthesis by DNA polymerase a from Drosophila melanogaster embryos.	Kaguni LS, Clayton DA	1982
Isolation of a herpesvirus-specific DNA polymerase from tissues of an American patient with Burkitt lymphoma.	Allaudeen HS, Bertino JR	1978
Single-molecule measurements of synthesis by DNA polymerase with base-pair resolution.	Christian TD, Romano LJ, Rueda D	2009
Roles of PCNA-binding and ubiquitin-binding domains in human DNA polymerase eta in translesion DNA synthesis.	Acharya N, Yoon JH, Gali H, Unk I, Haracska L, Johnson RE, Hurwitz J, Prakash L, Prakash S	2008
Rolling circle DNA replication in vitro by a complex of herpes simplex virus type 1-encoded enzymes.	Skaliter R, Lehman IR	1994
Posttranslational modification of the umuD-encoded subunit of Escherichia coli DNA polymerase V regulates its interactions with the beta processivity clamp.	Sutton MD, Narumi I, Walker GC	2002
Recombinational bypass of pyrimidine dimers promoted by the recA protein of Escherichia coli.	Livneh Z, Lehman IR	1982
A variant of DNA polymerase beta acts as a dominant negative mutant.	Bhattacharyya N, Banerjee S	1997
Dpb11, which interacts with DNA polymerase II(epsilon) in Saccharomyces cerevisiae, has a dual role in S-phase progression and at a cell cycle checkpoint.	Araki H, Leem SH, Phongdara A, Sugino A	1995
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Multiple forms of DNA polymerase in mouse myeloma.	Matsukage A, Bohn EW, Wilson SH	1974
A novel DNA polymerase activity found in association with intracisternal A-type particles.	Wilson SH, Kuff EL	1972
Differential correction of lagging-strand replication errors made by DNA polymerases {alpha} and {delta}.	Nick McElhinny SA, Kissling GE, Kunkel TA	2010
Fidelity of a human cell DNA replication complex.	Roberts JD, Kunkel TA	1988
Initiation of phi 29 DNA replication occurs at the second 3' nucleotide of the linear template: a sliding-back mechanism for protein-primed DNA replication.	Méndez J, Blanco L, Esteban JA, Bernad A, Salas M	1992
Optimization of DNA polymerase mutation rates during bacterial evolution.	Loh E, Salk JJ, Loeb LA	2010
Bacteriophage T7 gene 2.5 protein: an essential protein for DNA replication.	Kim YT, Richardson CC	1993
Two-dimensional infrared spectra reveal relaxation of the nonnucleoside inhibitor TMC278 complexed with HIV-1 reverse transcriptase.	Fang C, Bauman JD, Das K, Remorino A, Arnold E, Hochstrasser RM	2008
Template recognition sequence for RNA primer synthesis by gene 4 protein of bacteriophage T7.	Tabor S, Richardson CC	1981
Isolation of a specialized transducing bacteriophage lambda carrying the polC locus of Escherichia coli.	Shizuya H, Livingston DM, Richardson CC	1974
Isolation and partial characterization of a mutant of Escherichia coli deficient in DNA polymerase II.	Campbell JL, Soll L, Richardson CC	1972
Expression of soluble, enzymatically active, human immunodeficiency virus reverse transcriptase in Escherichia coli and analysis of mutants.	Hizi A, McGill C, Hughes SH	1988
Structural basis for the synthesis of nucleobase modified DNA by Thermus aquaticus DNA polymerase.	Obeid S, Baccaro A, Welte W, Diederichs K, Marx A	2010
Leading and lagging strand DNA synthesis in vitro by a reconstituted herpes simplex virus type 1 replisome.	Falkenberg M, Lehman IR, Elias P	2000
Synthesis and biological evaluation of fluorinated deoxynucleotide analogs based on bis-(difluoromethylene)triphosphoric acid.	Surya Prakash GK, Zibinsky M, Upton TG, Kashemirov BA, McKenna CE, Oertell K, Goodman MF, Batra VK, Pedersen LC, Beard WA, Shock DD, Wilson SH, Olah GA	2010
A model for DNA polymerase switching involving a single cleft and the rim of the sliding clamp.	Heltzel JM, Maul RW, Scouten Ponticelli SK, Sutton MD	2009
DNA polymerase epsilon and delta proofreading suppress discrete mutator and cancer phenotypes in mice.	Albertson TM, Ogawa M, Bugni JM, Hays LE, Chen Y, Wang Y, Treuting PM, Heddle JA, Goldsby RE, Preston BD	2009
A conditional lethal mutant of Escherichia coli K12 defective in the 5' leads to 3' exonuclease associated with DNA polymerase I.	Konrad EB, Lehman IR	1974
Translational frameshifting generates the gamma subunit of DNA polymerase III holoenzyme.	Tsuchihashi Z, Kornberg A	1990
HIV-1 reverse transcriptase connection subdomain mutations reduce template RNA degradation and enhance AZT excision.	Delviks-Frankenberry KA, Nikolenko GN, Boyer PL, Hughes SH, Coffin JM, Jere A, Pathak VK	2008
Synthesis by the DNA primase of Drosophila melanogaster of a primer with a unique chain length.	Conaway RC, Lehman IR	1982
Computer simulations of protein functions: searching for the molecular origin of the replication fidelity of DNA polymerases.	Florián J, Goodman MF, Warshel A	2005
Hybrid Ty1/HIV-1 elements used to detect inhibitors and monitor the activity of HIV-1 reverse transcriptase.	Nissley DV, Boyer PL, Garfinkel DJ, Hughes SH, Strathern JN	1998
Crystals of a ternary complex of human immunodeficiency virus type 1 reverse transcriptase with a monoclonal antibody Fab fragment and double-stranded DNA diffract x-rays to 3.5-A resolution.	Jacobo-Molina A, Clark AD, Williams RL, Nanni RG, Clark PK, Ferris AL, Hughes SH, Arnold E	1991
Regulation of oxidative DNA damage repair by DNA polymerase λ and MutYH by cross-talk of phosphorylation and ubiquitination.	Markkanen E, van Loon B, Ferrari E, Parsons JL, Dianov GL, Hübscher U	2011
Error-free replicative bypass of thymine glycol by the combined action of DNA polymerases kappa and zeta in human cells.	Yoon JH, Bhatia G, Prakash S, Prakash L	2010
Uracil incorporation: a source of pulse-labeled DNA fragments in the replication of the Escherichia coli chromosome.	Tye BK, Chien J, Lehman IR, Duncan BK, Warner HR	1978
A DNA binding protein specific for an origin of replication of herpes simplex virus type 1.	Elias P, O'Donnell ME, Mocarski ES, Lehman IR	1986
Yeast RPO41 gene product is required for transcription and maintenance of the mitochondrial genome.	Greenleaf AL, Kelly JL, Lehman IR	1986
A constant rate of spontaneous mutation in DNA-based microbes.	Drake JW	1991
Human DNA polymerase kappa forms nonproductive complexes with matched primer termini but not with mismatched primer termini.	Carlson KD, Johnson RE, Prakash L, Prakash S, Washington MT	2006
DNA polymerase 3 star requires ATP to start synthesis on a primed DNA.	Wickner W, Kornberg A	1973
Human immunodeficiency virus type 1 mutants resistant to nonnucleoside inhibitors of reverse transcriptase arise in tissue culture.	Richman D, Shih CK, Lowy I, Rose J, Prodanovich P, Goff S, Griffin J	1991
Binary complex crystal structure of DNA polymerase β reveals multiple conformations of the templating 8-oxoguanine lesion.	Batra VK, Shock DD, Beard WA, McKenna CE, Wilson SH	2011
A new form of DNA polymerase 3 and a copolymerase replicate a long, single-stranded primer-template.	Wickner W, Schekman R, Geider K, Kornberg A	1973
The dnaN gene codes for the beta subunit of DNA polymerase III holoenzyme of escherichia coli.	Burgers PM, Kornberg A, Sakakibara Y	1981
The delta subunit of Escherichia coli DNA polymerase III holoenzyme is the dnaX gene product.	Hübscher U, Kornberg A	1979
Binding of RNA template to a complex of HIV-1 reverse transcriptase/primer/template.	Canard B, Sarfati R, Richardson CC	1997
Mutations in the connection domain of HIV-1 reverse transcriptase increase 3'-azido-3'-deoxythymidine resistance.	Nikolenko GN, Delviks-Frankenberry KA, Palmer S, Maldarelli F, Fivash MJ, Coffin JM, Pathak VK	2007
Helicase-DNA polymerase interaction is critical to initiate leading-strand DNA synthesis.	Zhang H, Lee SJ, Zhu B, Tran NQ, Tabor S, Richardson CC	2011
Efficient translesion replication in the absence of Escherichia coli Umu proteins and 3'-5' exonuclease proofreading function.	Vandewiele D, Borden A, O'Grady PI, Woodgate R, Lawrence CW	1998
Ubiquitylation of yeast proliferating cell nuclear antigen and its implications for translesion DNA synthesis.	Haracska L, Unk I, Prakash L, Prakash S	2006
Isolation and characterization of a dideoxyguanosine triphosphate-resistant mutant of human immunodeficiency virus reverse transcriptase.	Prasad VR, Lowy I, de los Santos T, Chiang L, Goff SP	1991
Reconstitution of repair-gap UV mutagenesis with purified proteins from Escherichia coli: a role for DNA polymerases III and II.	Tomer G, Cohen-Fix O, O'Donnell ME, Goodman M, Livneh Z	1996
Human immunodeficiency virus type 1 (HIV-1) strains selected for resistance against the HIV-1-specific [2',5'-bis-O-(tert-butyldimethylsilyl)-3'-spiro- 5''-(4''-amino-1'',2''-oxathiole-2'',2''-dioxide)]-beta-D-pentofurano syl (TSAO) nucleoside analogues retain sensitivity to HIV-1-specific nonnucleoside inhibitors.	Balzarini J, Karlsson A, Vandamme AM, Pérez-Pérez MJ, Zhang H, Vrang L, Oberg B, Bäckbro K, Unge T, San-Félix A	1993
Human immunodeficiency virus 1 (HIV-1)-specific reverse transcriptase (RT) inhibitors may suppress the replication of specific drug-resistant (E138K)RT HIV-1 mutants or select for highly resistant (Y181C-->C181I)RT HIV-1 mutants.	Balzarini J, Karlsson A, Sardana VV, Emini EA, Camarasa MJ, De Clercq E	1994
A mutation in reverse transcriptase of bis(heteroaryl)piperazine-resistant human immunodeficiency virus type 1 that confers increased sensitivity to other nonnucleoside inhibitors.	Dueweke TJ, Pushkarskaya T, Poppe SM, Swaney SM, Zhao JQ, Chen IS, Stevenson M, Tarpley WG	1993
Identification of amino acids in herpes simplex virus DNA polymerase involved in substrate and drug recognition.	Gibbs JS, Chiou HC, Bastow KF, Cheng YC, Coen DM	1988
Rapid in vitro selection of human immunodeficiency virus type 1 resistant to 3'-thiacytidine inhibitors due to a mutation in the YMDD region of reverse transcriptase.	Tisdale M, Kemp SD, Parry NR, Larder BA	1993
Fifth mutation in human immunodeficiency virus type 1 reverse transcriptase contributes to the development of high-level resistance to zidovudine.	Kellam P, Boucher CA, Larder BA	1992
Suppression of the breakthrough of human immunodeficiency virus type 1 (HIV-1) in cell culture by thiocarboxanilide derivatives when used individually or in combination with other HIV-1-specific inhibitors (i.e., TSAO derivatives).	Balzarini J, Pérez-Pérez MJ, Vélazquez S, San-Félix A, Camarasa MJ, De Clercq E, Karlsson A	1995
Selective pressure of a quinoxaline nonnucleoside inhibitor of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT) on HIV-1 replication results in the emergence of nucleoside RT-inhibitor-specific (RT Leu-74-->Val or Ile and Val-75-->Leu or Ile) HIV-1 mutants.	Kleim JP, Rösner M, Winkler I, Paessens A, Kirsch R, Hsiou Y, Arnold E, Riess G	1996
DNA polymerase theta up-regulation is associated with poor survival in breast cancer, perturbs DNA replication, and promotes genetic instability.	Lemée F, Bergoglio V, Fernandez-Vidal A, Machado-Silva A, Pillaire MJ, Bieth A, Gentil C, Baker L, Martin AL, Leduc C, Lam E, Magdeleine E, Filleron T, Oumouhou N, Kaina B, Seki M, Grimal F, Lacroix-Triki M, Thompson A, Roché H, Bourdon JC, Wood RD, Hoffmann JS, Cazaux C	2010
Replication of adenovirus DNA-protein complex with purified proteins.	Ikeda JE, Enomoto T, Hurwitz J	1981
The alternative Ctf18-Dcc1-Ctf8-replication factor C complex required for sister chromatid cohesion loads proliferating cell nuclear antigen onto DNA.	Bermudez VP, Maniwa Y, Tappin I, Ozato K, Yokomori K, Hurwitz J	2003
Reconstitution of human replication factor C from its five subunits in baculovirus-infected insect cells.	Cai J, Uhlmann F, Gibbs E, Flores-Rozas H, Lee CG, Phillips B, Finkelstein J, Yao N, O'Donnell ME, Hurwitz J	1996
Association of phiX174 DNA-dependent ATPase activity with an Escherichia coli protein, replication factor Y, required for in vitro synthesis of phiX174 DNA.	Wickner S, Hurwitz J	1975
Studies of the cloned 37-kDa subunit of activator 1 (replication factor C) of HeLa cells.	Chen M, Pan ZQ, Hurwitz J	1992
Studies on the DNA elongation inhibitor and its proliferating cell nuclear antigen-dependent control in simian virus 40 DNA replication in vitro.	Lee SH, Kwong AD, Ishimi Y, Hurwitz J	1989
Role of DNA polymerase alpha and DNA primase in simian virus 40 DNA replication in vitro.	Murakami Y, Wobbe CR, Weissbach L, Dean FB, Hurwitz J	1986
DNA sequences required for the in vitro replication of adenovirus DNA.	Guggenheimer RA, Stillman BW, Nagata K, Tamanoi F, Hurwitz J	1984
Disclosing the in vivo organization of a viral histone-like protein in Bacillus subtilis mediated by its capacity to recognize the viral genome.	Holguera I, Ballesteros-Plaza D, Muñoz-Espín D, Salas M	2012
Properties of the human Cdc45/Mcm2-7/GINS helicase complex and its action with DNA polymerase {varepsilon} in rolling circle DNA synthesis.	Kang YH, Galal WC, Farina A, Tappin I, Hurwitz J	2012
Y265C DNA polymerase beta knockin mice survive past birth and accumulate base excision repair intermediate substrates.	Senejani AG, Dalal S, Liu Y, Nottoli TP, McGrath JM, Clairmont CS, Sweasy JB	2012
Structural basis of human DNA polymerase η-mediated chemoresistance to cisplatin.	Zhao Y, Biertümpfel C, Gregory MT, Hua YJ, Hanaoka F, Yang WW	2012
Genomic footprinting in mammalian cells with ultraviolet light.	Becker MM, Wang Z, Grossmann G, Becherer KA	1989
On the molecular basis of transition mutations: frequencies of forming 2-aminopurine.cytosine and adenine.cytosine base mispairs in vitro.	Watanabe SM, Goodman MF	1981
Replication of simian virus 40 origin-containing DNA in vitro with purified proteins.	Wobbe CR, Weissbach L, Borowiec JA, Dean FB, Murakami Y, Bullock P, Hurwitz J	1987
Mechanism of action of ribonuclease H isolated from avian myeloblastosis virus and Escherichia coli.	Leis JP, Berkower I, Hurwitz J	1973
In situ analysis of repair processes for oxidative DNA damage in mammalian cells.	Lan L, Nakajima S, Oohata Y, Takao M, Okano S, Masutani M, Wilson SH, Yasui A	2004
Different mutation signatures in DNA polymerase eta- and MSH6-deficient mice suggest separate roles in antibody diversification.	Martomo SA, Yang WW, Wersto RP, Ohkumo T, Kondo Y, Yokoi M, Masutani C, Hanaoka F, Gearhart PJ	2005
Structure of the gene 2.5 protein, a single-stranded DNA binding protein encoded by bacteriophage T7.	Hollis T, Stattel JM, Walther DS, Richardson CC, Ellenberger T	2001
An N-terminal fragment of the gene 4 helicase/primase of bacteriophage T7 retains primase activity in the absence of helicase activity.	Frick DN, Baradaran K, Richardson CC	1998
A general two-metal-ion mechanism for catalytic RNA.	Steitz TA, Steitz JA	1993
Viral terminal protein directs early organization of phage DNA replication at the bacterial nucleoid.	Muñoz-Espín D, Holguera I, Ballesteros-Plaza D, Carballido-López R, Salas M	2010
Direct role for the RNA polymerase domain of T7 primase in primer delivery.	Zhu B, Lee SJ, Richardson CC	2010
Residues in the central beta-hairpin of the DNA helicase of bacteriophage T7 are important in DNA unwinding.	Satapathy AK, Kochaniak AB, Mukherjee S, Crampton DJ, van Oijen AM, Richardson CC	2010
Human DINB1-encoded DNA polymerase kappa is a promiscuous extender of mispaired primer termini.	Washington MT, Johnson RE, Prakash L, Prakash S	2002
Genome-wide model for the normal eukaryotic DNA replication fork.	Larrea AA, Lujan SA, Nick McElhinny SA, Mieczkowski PA, Resnick MA, Gordenin DA, Kunkel TA	2010
Frameshift errors initiated by nucleotide misincorporation.	Bebenek K, Kunkel TA	1990
Infidelity of DNA synthesis associated with bypass of apurinic sites.	Schaaper RM, Kunkel TA, Loeb LA	1983
Intrinsic apurinic/apyrimidinic (AP) endonuclease activity enables Bacillus subtilis DNA polymerase X to recognize, incise, and further repair abasic sites.	Baños B, Villar L, Salas M, de Vega M	2010
Phage phi29 protein p56 prevents viral DNA replication impairment caused by uracil excision activity of uracil-DNA glycosylase.	Serrano-Heras G, Bravo A, Salas M	2008
The vinyl chloride DNA derivative N2,3-ethenoguanine produces G----A transitions in Escherichia coli.	Cheng KC, Preston BD, Cahill DS, Dosanjh MK, Singer B, Loeb LA	1991
Mutagenic potential of O4-methylthymine in vivo determined by an enzymatic approach to site-specific mutagenesis.	Preston BD, Singer B, Loeb LA	1986
Depurination causes mutations in SOS-induced cells.	Schaaper RM, Loeb LA	1981
Metal-induced infidelity during DNA synthesis.	Sirover MA, Loeb LA	1976
Reverse transcriptase: correlation of zinc content with activity.	Poiesz BJ, Seal G, Loeb LA	1974
Priming of DNA polymerase in nuclei of sea urchin embryos by native DNA.	Loeb LA, Mazia D, Ruby AD	1967
Translesion DNA polymerases remodel the replisome and alter the speed of the replicative helicase.	Indiani C, Langston LD, Yurieva O, Goodman MF, O'Donnell ME	2009
Roles of DNA polymerases V and II in SOS-induced error-prone and error-free repair in Escherichia coli.	Pham P, Rangarajan S, Woodgate R, Goodman MF	2001
A fidelity assay using "dideoxy" DNA sequencing: a measurement of sequence dependence and frequency of forming 5-bromouracil X guanine base mispairs.	Lasken RS, Goodman MF	1985
Evidence for an altered adenovirus DNA polymerase in cells infected with the mutant H5ts149.	Friefeld BR, Lichy JH, Hurwitz J, Horwitz MS	1983
Hopping of a processivity factor on DNA revealed by single-molecule assays of diffusion.	Komazin-Meredith G, Mirchev R, Golan DE, van Oijen AM, Coen DM	2008
Sequence and mapping analyses of the herpes simplex virus DNA polymerase gene predict a C-terminal substrate binding domain.	Gibbs JS, Chiou HC, Hall JD, Mount DW, Retondo MJ, Weller SK, Coen DM	1985
Adenovirus DNA replication in vitro: identification of a host factor that stimulates synthesis of the preterminal protein-dCMP complex.	Nagata K, Guggenheimer RA, Enomoto T, Lichy JH, Hurwitz J	1982
Adenovirus DNA replication in vitro: purification of the terminal protein in a functional form.	Enomoto T, Lichy JH, Ikeda JE, Hurwitz J	1981
Elongation of primed DNA templates by eukaryotic DNA polymerases.	Ikeda JE, Longiaru M, Horwitz MS, Hurwitz J	1980
The accessory subunit of mtDNA polymerase shares structural homology with aminoacyl-tRNA synthetases: implications for a dual role as a primer recognition factor and processivity clamp.	Fan L, Sanschagrin PC, Kaguni LS, Kuhn LA	1999
Crystal structure of the GINS complex and functional insights into its role in DNA replication.	Chang YP, Wang G, Bermudez V, Hurwitz J, Chen XS	2007
Studies on the interactions between human replication factor C and human proliferating cell nuclear antigen.	Zhang G, Gibbs E, Kelman Z, O'Donnell ME, Hurwitz J	1999
Sequence and expression in Escherichia coli of the 40-kDa subunit of activator 1 (replication factor C) of HeLa cells.	Chen M, Pan ZQ, Hurwitz J	1992
Molecular interactions in the priming complex of bacteriophage T7.	Kulczyk AW, Richardson CC	2012
Involvement of escherichia coli dnaZ gene product in DNA elongation in vitro.	Wickner S, Hurwitz J	1976
Initiation of replication in chromosomal DNA induced by extracts from proliferating cells.	Jazwinski SM, Wang JL, Edelman GM	1976
Chromosomal location of the human gene for DNA polymerase beta.	McBride OW, Zmudzka BZ, Wilson SH	1987
Structure of rat DNA polymerase beta revealed by partial amino acid sequencing and cDNA cloning.	Zmudzka BZ, SenGupta D, Matsukage A, Cobianchi F, Kumar P, Wilson SH	1986
A human homolog of the Saccharomyces cerevisiae REV3 gene, which encodes the catalytic subunit of DNA polymerase zeta.	Gibbs PE, McGregor WG, Maher VM, Nisson P, Lawrence CW	1998
Oncornavirus expression in human x mouse hybrid cells segregating mouse chromosomes.	Minna JD, Gazdar AF, Iverson GM, Marshall TH, STORMBERG K, Wilson SH	1974
Mutator phenotypes of yeast strains heterozygous for mutations in the MSH2 gene.	Drotschmann K, Clark AB, Tran HT, Resnick MA, Gordenin DA, Kunkel TA	1999
Unequal human immunodeficiency virus type 1 reverse transcriptase error rates with RNA and DNA templates.	Boyer JC, Bebenek K, Kunkel TA	1992
Lethal mutagenesis of HIV with mutagenic nucleoside analogs.	Loeb LA, Essigmann JM, Kazazi F, Zhang J, Rose KD, Mullins JI	1999
Posttranscriptional modification of retroviral primers is required for late stages of DNA replication.	Burnett BP, McHenry CS	1997
Reverse transcriptase of human immunodeficiency virus can use either human tRNA(3Lys) or Escherichia coli tRNA(2Gln) as a primer in an in vitro primer-utilization assay.	Kohlstaedt LA, Steitz TA	1992
Gene 1.7 of bacteriophage T7 confers sensitivity of phage growth to dideoxythymidine.	Tran NQ, Rezende LF, Qimron U, Richardson CC, Tabor S	2008
Initiation of DNA replication at the primary origin of bacteriophage T7 by purified proteins: requirement for T7 RNA polymerase.	Romano LJ, Tamanoi F, Richardson CC	1981
The gamma subunit of DNA polymerase III holoenzyme of Escherichia coli is produced by ribosomal frameshifting.	Flower AM, McHenry CS	1990
UmuC mutagenesis protein of Escherichia coli: purification and interaction with UmuD and UmuD'.	Woodgate R, Rajagopalan M, Lu C, Echols H	1989
Conversion of phiX174 and fd single-stranded DNA to replicative forms in extracts of Escherichia coli.	Wickner RB, Wright M, Wickner S, Hurwitz J	1972
Two distinct loci confer resistance to acycloguanosine in herpes simplex virus type 1.	Coen DM, Schaffer PA	1980
Conversion of phiX174 viral DNA to double-stranded form by purified Escherichia coli proteins.	Wickner S, Hurwitz J	1974
Studies on the initiation of simian virus 40 replication in vitro: RNA primer synthesis and its elongation.	Murakami Y, Eki T, Hurwitz J	1992
Studies on the initiation and elongation reactions in the simian virus 40 DNA replication system.	Matsumoto T, Eki T, Hurwitz J	1990
Involvement of two protein factors and ATP in in vitro DNA synthesis catalyzed by DNA polymerase 3 of Escherichia coli.	Hurwitz J, Wickner S	1974
ATP hydrolysis catalyzed by human replication factor C requires participation of multiple subunits.	Cai J, Yao N, Gibbs E, Finkelstein J, Phillips B, O'Donnell ME, Hurwitz J	1998
In vitro reconstitution of human replication factor C from its five subunits.	Uhlmann F, Cai J, Flores-Rozas H, Dean FB, Finkelstein J, O'Donnell ME, Hurwitz J	1996
The subunits of activator 1 (replication factor C) carry out multiple functions essential for proliferating-cell nuclear antigen-dependent DNA synthesis.	Pan ZQ, Chen M, Hurwitz J	1993
Species-specific in vitro synthesis of DNA containing the polyoma virus origin of replication.	Murakami Y, Eki T, Yamada M, Prives C, Hurwitz J	1986
Adenovirus DNA replication in vitro: synthesis of full-length DNA with purified proteins.	Nagata K, Guggenheimer RA, Hurwitz J	1983
Adenoviral protein-primed initiation of DNA chains in vitro.	Ikeda JE, Enomoto T, Hurwitz J	1982
Mechanism of ultraviolet-induced mutagenesis: extent and fidelity of in vitro DNA synthesis on irradiated templates.	Villani G, Boiteux S, Radman M	1978
Knotted DNA from bacteriophage capsids.	Liu LF, Perkocha L, Calendar R, Wang JC	1981
Reverse chemical mutagenesis: identification of the mutagenic lesions resulting from reactive oxygen species-mediated damage to DNA.	Feig DI, Sowers LC, Loeb LA	1994
Structural basis of asymmetry in the human immunodeficiency virus type 1 reverse transcriptase heterodimer.	Wang J, Smerdon SJ, Jäger J, Kohlstaedt LA, Rice PA, Friedman JM, Steitz TA	1994
Recognition by viral and cellular DNA polymerases of nucleosides bearing bases with nonstandard hydrogen bonding patterns.	Horlacher J, Hottiger M, Podust VN, Hübscher U, Benner SA	1995
Active DNA unwinding dynamics during processive DNA replication.	Morin JA, Cao FJ, Lázaro JM, Arias-Gonzalez JR, Valpuesta JM, Carrascosa JL, Salas M, Ibarra B	2012
The p15 carboxyl-terminal proteolysis product of the human immunodeficiency virus type 1 reverse transcriptase p66 has DNA polymerase activity.	Hafkemeyer P, Ferrari E, Brecher J, Hübscher U	1991
The joining (J) chain is present in invertebrates that do not express immunoglobulins.	Takahashi T, Iwase T, Takenouchi N, Saito M, Kobayashi K, Moldoveanu Z, Mestecky J, Moro I	1996
Suppressed catalytic activity of base excision repair enzymes on rotationally positioned uracil in nucleosomes.	Beard BC, Wilson SH, Smerdon MJ	2003
A short adaptive path from DNA to RNA polymerases.	Cozens C, Pinheiro VB, Vaisman A, Woodgate R, Holliger P	2012
Gene 5.5 protein of bacteriophage T7 in complex with Escherichia coli nucleoid protein H-NS and transfer RNA masks transfer RNA priming in T7 DNA replication.	Zhu B, Lee SJ, Tan M, Wang ED, Richardson CC	2012
Pol31 and Pol32 subunits of yeast DNA polymerase δ are also essential subunits of DNA polymerase ζ	Johnson RE, Prakash L, Prakash S	2012
2',5'-Bis-O-(tert-butyldimethylsilyl)-3'-spiro-5''-(4''-amino-1'',2''- oxathiole-2'',2'-dioxide)pyrimidine (TSAO) nucleoside analogues: highlyselective inhibitors of human immunodeficiency virus type 1 that are targeted at the viral reverse transcriptase.	Balzarini J, Pérez-Pérez MJ, San-Félix A, Schols D, Perno CF, Vandamme AM, Camarasa MJ, De Clercq E	1992
Mechanism of inhibitory effect of dextran sulfate and heparin on replication of human immunodeficiency virus in vitro.	Baba M, Pauwels R, Balzarini J, Arnout J, Desmyter J, De Clercq E	1988
Inhibition of oncornavirus functions by 2'-azido polynucleotides.	De Clercq E, Billiau A, Hobbs J, Torrence PF, Witkop B	1975
Importance of compartment formation for a self-encoding system.	Matsuura T, Yamaguchi M, Ko-Mitamura EP, Shima Y, Urabe I, Yomo T	2002
9-[(2RS)-3-fluoro-2-phosphonylmethoxypropyl] derivatives of purines: a class of highly selective antiretroviral agents in vitro and in vivo.	Balzarini J, Holy A, Jindrich J, Dvorakova H, Hao Z, Snoeck R, Herdewijn P, Johns DG, De Clercq E	1991
Mutated K65R recombinant reverse transcriptase of human immunodeficiency virus type 1 shows diminished chain termination in the presence of 2',3'-dideoxycytidine 5'-triphosphate and other drugs.	Gu Z, Arts EJ, Parniak MA, Wainberg MA	1995
On the mechanism of selective inhibition of herpesvirus replication by (E)-5-(2-bromovinyl)-2'-deoxyuridine.	Allaudeen HS, Kozarich JW, Bertino JR, De Clercq E	1981
Potent and selective inhibition of human immunodeficiency virus type 1 (HIV-1) by 5-ethyl-6-phenylthiouracil derivatives through their interaction with the HIV-1 reverse transcriptase.	Baba M, De Clercq E, Tanaka H, Ubasawa M, Takashima H, Sekiya K, Nitta I, Umezu K, Nakashima H, Mori S	1991
Mechanism of somatic hypermutation at the WA motif by human DNA polymerase η	Zhao Y, Gregory MT, Biertümpfel C, Hua YJ, Hanaoka F, Yang WW	2013
Dual role for mammalian DNA polymerase ζ in maintaining genome stability and proliferative responses.	Lange SS, Bedford E, Reh S, Wittschieben JP, Carbajal S, Kusewitt DF, DiGiovanni J, Wood RD	2013
RecA acts as a switch to regulate polymerase occupancy in a moving replication fork.	Indiani C, Patel M, Goodman MF, O'Donnell ME	2013
Evidence for allosterism in in vitro DNA synthesis on RNA templates.	Cavalieri LF, Modak MJ, Marcus SL	1974
Structure-function analysis of ribonucleotide bypass by B family DNA replicases.	Clausen AR, Murray MS, Passer AR, Pedersen LC, Kunkel TA	2013
DNA polymerase δ-interacting protein 2 is a processivity factor for DNA polymerase λ during 8-oxo-7,8-dihydroguanine bypass.	Maga G, Crespan E, Markkanen E, Imhof R, Furrer A, Villani G, Hübscher U, van Loon B	2013
ENZYMATIC SYNTHESIS OF DEOXYRIBONUCLEIC ACID, XVI. OLIGONUCLEOTIDES AS TEMPLATES AND THE MECHANISM OF THEIR REPLICATION.	Kornberg A, BERTSCH LL, JACKSON JF, KHORANA HG	1964

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