| DNA polymerase I gene of Saccharomyces cerevisiae: nucleotide sequence, mapping of a temperature-sensitive mutation, and protein homology with other DNA polymerases. |
Pizzagalli A, Valsasnini P, Plevani P, Lucchini G |
1988 |
| Intervening sequences in an Archaea DNA polymerase gene. |
Perler FB, Comb DG, Jack WE, Moran LS, Qiang B, Kucera RB, Benner J, Slatko BE, Nwankwo DO, Hempstead SK |
1992 |
| Computer analysis of retroviral pol genes: assignment of enzymatic functions to specific sequences and homologies with nonviral enzymes. |
Johnson MS, McClure MA, Feng DF, Gray J, Doolittle RF |
1986 |
| Mechanism of DNA chain growth. I. Possible discontinuity and unusual secondary structure of newly synthesized chains. |
Okazaki R, Okazaki T, Sakabe K, Sugimoto K, Sugino A |
1968 |
| Mitochondrial DNA polymerase editing mutation, PolgD257A, reduces the diabetic phenotype of Akita male mice by suppressing appetite. |
Fox R, Kim HS, Reddick RL, Kujoth GC, Prolla TA, Tsutsumi S, Wada Y, Smithies O, Maeda N |
2011 |
| Correlation of somatic hypermutation specificity and A-T base pair substitution errors by DNA polymerase eta during copying of a mouse immunoglobulin kappa light chain transgene. |
Pavlov YI, Rogozin IB, Galkin AP, Aksenova AY, Hanaoka F, Rada C, Kunkel TA |
2002 |
| DNA polymerase beta bypasses in vitro a single d(GpG)-cisplatin adduct placed on codon 13 of the HRAS gene. |
Hoffmann JS, Pillaire MJ, Maga G, Podust V, Hübscher U, Villani G |
1995 |
| Capacity of RecA protein to bind preferentially to UV lesions and inhibit the editing subunit (epsilon) of DNA polymerase III: a possible mechanism for SOS-induced targeted mutagenesis. |
Lu C, Scheuermann RH, Echols H |
1986 |
| The arginine finger of bacteriophage T7 gene 4 helicase: role in energy coupling. |
Crampton DJ, Guo S, Johnson DE, Richardson CC |
2004 |
| Crystal structures of 2-acetylaminofluorene and 2-aminofluorene in complex with T7 DNA polymerase reveal mechanisms of mutagenesis. |
Dutta S, Li Y, Johnson DE, Dzantiev L, Richardson CC, Romano LJ, Ellenberger T |
2004 |
| Molecular cloning and expression of the Saccharomyces cerevisiae RFC3 gene, an essential component of replication factor C. |
Li X, Burgers PM |
1994 |
| Analysis of cytokine mRNA and DNA: detection and quantitation by competitive polymerase chain reaction. |
Gilliland G, Perrin S, Blanchard K, Bunn HF |
1990 |
| A genetic system to identify DNA polymerase beta mutator mutants. |
Washington SL, Yoon MS, Chagovetz AM, Li SX, Clairmont CA, Preston BD, Eckert KA, Sweasy JB |
1997 |
| Mutants in the Exo I motif of Escherichia coli dnaQ: defective proofreading and inviability due to error catastrophe. |
Fijalkowska I, Schaaper RM |
1996 |
| Heterogeneity of primer extension products in asymmetric PCR is due both to cleavage by a structure-specific exo/endonuclease activity of DNA polymerases and to premature stops. |
Tombline G, Bellizzi D, Sgaramella V |
1996 |
| Human coronavirus NL63 employs the severe acute respiratory syndrome coronavirus receptor for cellular entry. |
Hofmann H, Pyrc K, van der Hoek L, Geier M, Berkhout B, Pöhlmann S |
2005 |
| Replication by a single DNA polymerase of a stretched single-stranded DNA. |
Maier B, Bensimon D, Croquette V |
2000 |
| Comparison of the 5' nuclease activities of taq DNA polymerase and its isolated nuclease domain. |
Lyamichev V, Brow MA, Varvel VE, Dahlberg JE |
1999 |
| Eukaryotic DNA polymerase amino acid sequence required for 3'----5' exonuclease activity. |
Morrison A, Bell JB, Kunkel TA, Sugino A |
1991 |
| A phenotype for enigmatic DNA polymerase II: a pivotal role for pol II in replication restart in UV-irradiated Escherichia coli. |
Rangarajan S, Woodgate R, Goodman MF |
1999 |
| HOMOLOGY BETWEEN RNA FROM ROUS SARCOMA VIROUS AND DNA FROM ROUS SARCOMA VIRUS-INFECTED CELLS. |
TEMIN HM |
1964 |
| Proofreading DNA: recognition of aberrant DNA termini by the Klenow fragment of DNA polymerase I. |
Carver TE, Hochstrasser RA, Millar DP |
1994 |
| Crystal structure of the large fragment of Thermus aquaticus DNA polymerase I at 2.5-A resolution: structural basis for thermostability. |
Korolev S, Nayal M, Barnes WM, Di Cera E, Waksman G |
1995 |
| DNA polymerase activities in differentiating mouse neuroblastoma N-18 cells. |
Bhattacharya P, Basu S |
1978 |
| DNA polymerase II is encoded by the DNA damage-inducible dinA gene of Escherichia coli. |
Bonner CA, Hays S, McEntee K, Goodman MF |
1990 |
| Site-specifically modified oligodeoxyribonucleotides as templates for Escherichia coli DNA polymerase I. |
O'Connor D, Stöhrer G |
1985 |
| Proofreading-defective DNA polymerase II increases adaptive mutation in Escherichia coli. |
Foster PL, Gudmundsson G, Trimarchi JM, Cai H, Goodman MF |
1995 |
| Alternate pathways of DNA replication: DNA polymerase I-dependent replication. |
Niwa O, Bryan SK, Moses RE |
1981 |
| DNA polymerase III gene of Bacillus subtilis. |
Sanjanwala B, Ganesan AT |
1989 |
| Proofreading by the epsilon subunit of Escherichia coli DNA polymerase III increases the fidelity of calf thymus DNA polymerase alpha. |
Perrino FW, Loeb LA |
1989 |
| Ubiquitin-binding motif of human DNA polymerase eta is required for correct localization. |
Sabbioneda S, Green CM, Bienko M, Kannouche PL, Dikic I, Lehmann AR |
2009 |
| Expression in Escherichia coli of a fusion protein product containing a region of the adenovirus DNA polymerase. |
Rekosh D, Lindenbaum J, Brewster J, Mertz LM, Hurwitz J, Prestine L |
1985 |
| A peptide switch regulates DNA polymerase processivity. |
López de Saro FJ, Georgescu RE, O'Donnell ME |
2003 |
| The enzymatic repair of DNA. I. Formation of circular lambda-DNA. |
Gefter ML, Becker A, Hurwitz J |
1967 |
| Exchange of DNA polymerases at the replication fork of bacteriophage T7. |
Johnson DE, Takahashi M, Hamdan SM, Lee SJ, Richardson CC |
2007 |
| Enzymatic synthesis of DNA. 23. Synthesis of circular replicative form of phage phi-X174 DNA. |
Goulian M, Kornberg A |
1967 |
| Overproduction of the epsilon subunit of DNA polymerase III counteracts the SOS mutagenic response of Escherichia coli. |
Jonczyk P, Fijalkowska I, Ciesla Z |
1988 |
| The many faces of DNA polymerases: strategies for mutagenesis and for mutational avoidance. |
Friedberg EC, Feaver WJ, Gerlach VL |
2000 |
| UmuD'(2)C is an error-prone DNA polymerase, Escherichia coli pol V. |
Tang M, Shen X, Frank EG, O'Donnell ME, Woodgate R, Goodman MF |
1999 |
| Mechanism of DNA elongation catalyzed by Escherichia coli DNA polymerase III, dnaZ protein, and DNA elongation factors I and III. |
Wickner S |
1976 |
| The highly conserved amino acid sequence motif Tyr-Gly-Asp-Thr-Asp-Ser in alpha-like DNA polymerases is required by phage phi 29 DNA polymerase for protein-primed initiation and polymerization. |
Bernad A, Lázaro JM, Salas M, Blanco L |
1990 |
| Isothermal in vitro amplification of DNA by a restriction enzyme/DNA polymerase system. |
Walker GT, Little MC, Nadeau JG, Shank DD |
1992 |
| Cloning of thermostable DNA polymerases from hyperthermophilic marine Archaea with emphasis on Thermococcus sp. 9 degrees N-7 and mutations affecting 3'-5' exonuclease activity. |
Southworth MW, Kong H, Kucera RB, Ware J, Jannasch HW, Perler FB |
1996 |
| Tuning and switching a DNA polymerase motor with mechanical tension. |
Goel A, Astumian RD, Herschbach D |
2003 |
| Dissection of functional domains of adenovirus DNA polymerase by linker-insertion mutagenesis. |
Chen M, Horwitz MS |
1989 |
| Suppression of chemical mutagenesis in bacteriophage T4 by genetically modified DNA polymerases. |
Drake JW, Greening EO |
1970 |
| Unique features in the structure of the complex between HIV-1 reverse transcriptase and the bis(heteroaryl)piperazine (BHAP) U-90152 explain resistance mutations for this nonnucleoside inhibitor. |
Esnouf RM, Ren J, Hopkins AL, Ross CK, Jones EY, Stammers DK, Stuart DI |
1997 |
| Exonucleolytic proofreading of leading and lagging strand DNA replication errors. |
Roberts JD, Thomas DC, Kunkel TA |
1991 |
| Cell-cycle dependence and properties of the HeLa cell DNA polymerase system. |
Delfini C, Alfani E, De Venezia V, Oberholtzer G, Tomasello C, Eremenko T, Volpe P |
1985 |
| Intracellular metabolism and mechanism of anti-retrovirus action of 9-(2-phosphonylmethoxyethyl)adenine, a potent anti-human immunodeficiency virus compound. |
Balzarini J, Hao Z, Herdewijn P, Johns DG, De Clercq E |
1991 |
| Hydroxyl radical footprint analysis of human immunodeficiency virus reverse transcriptase-template.primer complexes. |
Metzger W, Hermann T, Schatz O, Le Grice SF, Heumann H |
1993 |
| Mismatch-specific thymine DNA glycosylase and DNA polymerase beta mediate the correction of G.T mispairs in nuclear extracts from human cells. |
Wiebauer K, Jiricny J |
1990 |
| The fifth essential DNA polymerase phi in Saccharomyces cerevisiae is localized to the nucleolus and plays an important role in synthesis of rRNA. |
Shimizu K, Kawasaki Y, Hiraga S, Tawaramoto M, Nakashima N, Sugino A |
2002 |
| Processive DNA synthesis observed in a polymerase crystal suggests a mechanism for the prevention of frameshift mutations. |
Johnson SJ, Taylor JS, Beese LS |
2003 |
| Properties of a soluble DNA polymerase isolated from Rous sarcoma virus. |
Duesberg P, Helm KV, Canaani E |
1971 |
| Low levels of deoxynucleotides in peripheral blood lymphocytes: a strategy to inhibit human immunodeficiency virus type 1 replication. |
Gao WY, Cara A, Gallo RC, Lori F |
1993 |
| Extension of mismatched 3' termini of DNA is a major determinant of the infidelity of human immunodeficiency virus type 1 reverse transcriptase. |
Perrino FW, Preston BD, Sandell LL, Loeb LA |
1989 |
| Domain structure of the Moloney murine leukemia virus reverse transcriptase: mutational analysis and separate expression of the DNA polymerase and RNase H activities. |
Tanese N, Goff SP |
1988 |
| Comparison between DNA melting thermodynamics and DNA polymerase fidelity. |
Petruska J, Goodman MF, Boosalis MS, Sowers LC, Cheong C, Tinoco I |
1988 |
| Deoxynucleoside [1-thio]triphosphates prevent proofreading during in vitro DNA synthesis. |
Kunkel TA, Eckstein F, Mildvan AS, Koplitz RM, Loeb LA |
1981 |
| Thermostable DNA polymerase chain amplification of t(14;18) chromosome breakpoints and detection of minimal residual disease. |
Crescenzi M, Seto M, Herzig GP, Weiss PD, Griffith RC, Korsmeyer SJ |
1988 |
| The influence of neighboring base pairs upon base-pair substitution mutation rates. |
Koch RE |
1971 |
| Sensitivity of wild-type human immunodeficiency virus type 1 reverse transcriptase to dideoxynucleotides depends on template length; the sensitivity of drug-resistant mutants does not. |
Boyer PL, Tantillo C, Jacobo-Molina A, Nanni RG, Ding J, Arnold E, Hughes SH |
1994 |
| Targeting of human DNA polymerase iota to the replication machinery via interaction with PCNA. |
Haracska L, Johnson RE, Unk I, Phillips BB, Hurwitz J, Prakash L, Prakash S |
2001 |
| Overexpression of DNA polymerase beta in cell results in a mutator phenotype and a decreased sensitivity to anticancer drugs. |
Canitrot Y, Cazaux C, Fréchet M, Bouayadi K, Lesca C, Salles B, Hoffmann JS |
1998 |
| Directed evolution of novel polymerase activities: mutation of a DNA polymerase into an efficient RNA polymerase. |
Xia G, Chen L, Sera T, Fa M, Schultz PG, Romesberg FE |
2002 |
| Fidelity of DNA polymerases in DNA amplification. |
Keohavong P, Thilly WG |
1989 |
| Variations of DNA polymerase-alpha and -beta during prolonged stimulation of human lymphocytes. |
Bertazzoni U, Stefanini M, Noy GP, Giulotto E, Nuzzo F, Falaschi A, Spadari S |
1976 |
| A beta-like DNA polymerase activity in the slime mold Dictyostelium discoideum. |
Baril EF, Scheiner C, Pederson T |
1980 |
| Functional interaction between the Werner Syndrome protein and DNA polymerase delta. |
Kamath-Loeb AS, Johansson E, Burgers PM, Loeb LA |
2000 |
| A structural gap in Dpo4 supports mutagenic bypass of a major benzo[a]pyrene dG adduct in DNA through template misalignment. |
Bauer J, Xing G, Yagi H, Sayer JM, Jerina DM, Ling H |
2007 |
| A single mutation in poliovirus RNA-dependent RNA polymerase confers resistance to mutagenic nucleotide analogs via increased fidelity. |
Pfeiffer JK, Kirkegaard K |
2003 |
| Mice reconstituted with DNA polymerase beta-deficient fetal liver cells are able to mount a T cell-dependent immune response and mutate their Ig genes normally. |
Esposito G, Texido G, Betz UA, Gu H, Müller W, Klein U, Rajewsky K |
2000 |
| Degradation of DNA RNA hybrids by ribonuclease H and DNA polymerases of cellular and viral origin. |
Keller W, Crouch R |
1972 |
| The Escherichia coli SOS mutagenesis proteins UmuD and UmuD' interact physically with the replicative DNA polymerase. |
Sutton MD, Opperman T, Walker GC |
1999 |
| Random mutagenesis of Thermus aquaticus DNA polymerase I: concordance of immutable sites in vivo with the crystal structure. |
Suzuki M, Baskin D, Hood L, Loeb LA |
1996 |
| DNA polymerase delta isolated from Schizosaccharomyces pombe contains five subunits. |
Zuo S, Gibbs E, Kelman Z, Wang TS, O'Donnell ME, MacNeill SA, Hurwitz J |
1997 |
| Polkappa protects mammalian cells against the lethal and mutagenic effects of benzo[a]pyrene. |
Ogi T, Shinkai Y, Tanaka K, Ohmori H |
2002 |
| A specific subdomain in phi29 DNA polymerase confers both processivity and strand-displacement capacity. |
Rodríguez I, Lázaro JM, Blanco L, Kamtekar S, Berman AJ, Wang J, Steitz TA, Salas M, de Vega M |
2005 |
| Error-prone replication of repeated DNA sequences by T7 DNA polymerase in the absence of its processivity subunit. |
Kunkel TA, Patel SS, Johnson KA |
1994 |
| Phosphorylation of a high molecular weight DNA polymerase alpha. |
Donaldson RW, Gerner EW |
1987 |
| A defective phage system reveals bacteriophage T4 replication origins that coincide with recombination hot spots. |
Kreuzer KN, Alberts BM |
1985 |
| Comparison of nucleotide interactions in water, proteins, and vacuum: model for DNA polymerase fidelity. |
Petruska J, Sowers LC, Goodman MF |
1986 |
| Interaction of human apurinic endonuclease and DNA polymerase beta in the base excision repair pathway. |
Bennett RA, Wilson DM, Wong D, Demple B |
1997 |
| A single residue in DNA polymerases of the Escherichia coli DNA polymerase I family is critical for distinguishing between deoxy- and dideoxyribonucleotides. |
Tabor S, Richardson CC |
1995 |
| Incorrect nucleotide insertion at the active site of a G:A mismatch catalyzed by DNA polymerase beta. |
Lin P, Batra VK, Pedersen LC, Beard WA, Wilson SH, Pedersen LG |
2008 |
| 2-Aminopurine-induced mutagenesis in T4 bacteriophage: a model relating mutation frequency to 2-aminopurine incorporation in DNA. |
Goodman MF, Hopkins R, Gore WC |
1977 |
| Human immunodeficiency virus type 1 reverse transcriptase: spatial and temporal relationship between the polymerase and RNase H activities. |
Gopalakrishnan V, Peliska JA, Benkovic SJ |
1992 |
| Escherichia coli polymerase I can use O2-methyldeoxythymidine or O4-methyldeoxythymidine in place of deoxythymidine in primed poly(dA-dT).poly(dA-dT) synthesis. |
Singer B, Sági J, Kuśmierek JT |
1983 |
| Construction and characterization of a bacteriophage T4 DNA polymerase deficient in 3'-->5' exonuclease activity. |
Frey MW, Nossal NG, Capson TL, Benkovic SJ |
1993 |
| A structural rationale for stalling of a replicative DNA polymerase at the most common oxidative thymine lesion, thymine glycol. |
Aller P, Rould MA, Hogg M, Wallace SS, Doublié S |
2007 |
| Conformational changes induced in herpes simplex virus DNA polymerase upon DNA binding. |
Weisshart K, Kuo AA, Painter GR, Wright LL, Furman PA, Coen DM |
1993 |
| Highly mutagenic replication by DNA polymerase V (UmuC) provides a mechanistic basis for SOS untargeted mutagenesis. |
Maor-Shoshani A, Reuven NB, Tomer G, Livneh Z |
2000 |
| Purification of DNA polymerase II stimulatory factor I, a yeast single-stranded DNA-binding protein. |
Brown WC, Smiley JK, Campbell JL |
1990 |
| Frequent deletions and down-regulation of micro- RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia. |
Calin GA, Dumitru CD, Shimizu M, Bichi R, Zupo S, Noch E, Aldler H, Rattan S, Keating M, Rai K, Rassenti L, Kipps T, Negrini M, Bullrich F, Croce CM |
2002 |
| Oxidation state of the XRCC1 N-terminal domain regulates DNA polymerase beta binding affinity. |
Cuneo MJ, London RE |
2010 |
| RNA-primed DNA synthesis: specific catalysis by HeLa cell DNA polymerase alpha. |
Spadari S, Weissbach A |
1975 |
| Homology between DNA polymerases of poxviruses, herpesviruses, and adenoviruses: nucleotide sequence of the vaccinia virus DNA polymerase gene. |
Earl PL, Jones EV, Moss B |
1986 |
| Evidence that a high molecular weight replicative DNA polymerase is conserved during evolution. |
Hübscher U, Spanos A, Albert W, Grummt F, Banks GR |
1981 |
| Isolation of an intact DNA polymerase-primase from embryos of Drosophila melanogaster. |
Kaguni LS, Rossignol JM, Conaway RC, Lehman IR |
1983 |
| Mutagenesis during in vitro DNA synthesis. |
Weymouth LA, Loeb LA |
1978 |
| Role of human DNA polymerase kappa as an extender in translesion synthesis. |
Haracska L, Prakash L, Prakash S |
2002 |
| Werner syndrome protein interacts functionally with translesion DNA polymerases. |
Kamath-Loeb AS, Lan L, Nakajima S, Yasui A, Loeb LA |
2007 |
| Identification of 5'-deoxyribose phosphate lyase activity in human DNA polymerase gamma and its role in mitochondrial base excision repair in vitro. |
Longley MJ, Prasad R, Srivastava DK, Wilson SH, Copeland WC |
1998 |
| Phage phi29 and Nf terminal protein-priming domain specifies the internal template nucleotide to initiate DNA replication. |
Longás E, Villar L, Lázaro JM, de Vega M, Salas M |
2008 |
| Werner protein recruits DNA polymerase delta to the nucleolus. |
Szekely AM, Chen YH, Zhang C, Oshima J, Weissman SM |
2000 |
| Purification in a functional form of the terminal protein of Bacillus subtilis phage phi 29. |
Prieto I, Lázaro JM, García JA, Hermoso JM, Salas M |
1984 |
| Terminal protein-primed DNA amplification. |
Blanco L, Lázaro JM, de Vega M, Bonnin A, Salas M |
1994 |
| Exonucleolytic proofreading by calf thymus DNA polymerase delta. |
Kunkel TA, Sabatino RD, Bambara RA |
1987 |
| Structural analysis of the inactive state of the Escherichia coli DNA polymerase clamp-loader complex. |
Kazmirski SL, Podobnik M, Weitze TF, O'Donnell ME, Kuriyan J |
2004 |
| A separate editing exonuclease for DNA replication: the epsilon subunit of Escherichia coli DNA polymerase III holoenzyme. |
Scheuermann RH, Echols H |
1984 |
| DNA polymerization in the absence of exonucleolytic proofreading: in vivo and in vitro studies. |
Reha-Krantz LJ, Stocki S, Nonay RL, Dimayuga E, Goodrich LD, Konigsberg WH, Spicer EK |
1991 |
| A unique loop in the DNA-binding crevice of bacteriophage T7 DNA polymerase influences primer utilization. |
Chowdhury K, Tabor S, Richardson CC |
2000 |
| De novo synthesis of budding yeast DNA polymerase alpha and POL1 transcription at the G1/S boundary are not required for entrance into S phase. |
Muzi Falconi M, Piseri A, Ferrari M, Lucchini G, Plevani P, Foiani M |
1993 |
| The kinetoplast structure-specific endonuclease I is related to the 5' exo/endonuclease domain of bacterial DNA polymerase I and colocalizes with the kinetoplast topoisomerase II and DNA polymerase beta during replication. |
Engel ML, Ray DS |
1999 |
| The 3'-->5' exonuclease of DNA polymerase delta can substitute for the 5' flap endonuclease Rad27/Fen1 in processing Okazaki fragments and preventing genome instability. |
Jin YH, Obert R, Burgers PM, Kunkel TA, Resnick MA, Gordenin DA |
2001 |
| Evidence for a role for DNA polymerase beta in mammalian meiosis. |
Plug AW, Clairmont CA, Sapi E, Ashley T, Sweasy JB |
1997 |
| Resolution of the diadenosine 5',5"'-P1,P4-tetraphosphate binding subunit from a multiprotein form of HeLa cell DNA polymerase alpha. |
Baril E, Bonin P, Burstein D, Mara K, Zamecnik P |
1983 |
| Escherichia coli DNA polymerase II catalyzes chromosomal and episomal DNA synthesis in vivo. |
Rangarajan S, Gudmundsson G, Qiu Z, Foster PL, Goodman MF |
1997 |
| Construction of a plasmid that overproduces the large proteolytic fragment (Klenow fragment) of DNA polymerase I of Escherichia coli. |
Joyce CM, Grindley ND |
1983 |
| The cellular DNA polymerase alpha-primase is required for papillomavirus DNA replication and associates with the viral E1 helicase. |
Park P, Copeland W, Yang L, Wang T, Botchan MR, Mohr IJ |
1994 |
| Structure of PolC reveals unique DNA binding and fidelity determinants. |
Evans RJ, Davies DR, Bullard JM, Christensen J, Green LS, Guiles JW, Pata JD, Ribble WK, Janjic N, Jarvis TC |
2008 |
| Design and synthesis of a 3'-O-allyl photocleavable fluorescent nucleotide as a reversible terminator for DNA sequencing by synthesis. |
Ruparel H, Bi L, Li Z, Bai X, Kim DH, Turro NJ, Ju J |
2005 |
| The Tyr-265-to-Cys mutator mutant of DNA polymerase beta induces a mutator phenotype in mouse LN12 cells. |
Clairmont CA, Narayanan L, Sun KW, Glazer PM, Sweasy JB |
1999 |
| Cloning and expression of T4 DNA polymerase. |
Lin TC, Rush J, Spicer EK, Konigsberg WH |
1987 |
| Human and mouse homologs of Escherichia coli DinB (DNA polymerase IV), members of the UmuC/DinB superfamily. |
Gerlach VL, Aravind L, Gotway G, Schultz RA, Koonin EV, Friedberg EC |
1999 |
| Structure of the HIV-1 integrase catalytic domain complexed with an inhibitor: a platform for antiviral drug design. |
Goldgur Y, Craigie R, Cohen GH, Fujiwara T, Yoshinaga T, Fujishita T, Sugimoto H, Endo T, Murai H, Davies DR |
1999 |
| Orchestration of cooperative events in DNA synthesis and repair mechanism unraveled by transition path sampling of DNA polymerase beta's closing. |
Radhakrishnan R, Schlick T |
2004 |
| Biochemical evidence for the requirement of Hoogsteen base pairing for replication by human DNA polymerase iota. |
Johnson RE, Prakash L, Prakash S |
2005 |
| Identification of the epsilon-subunit of Escherichia coli DNA polymerase III holoenzyme as the dnaQ gene product: a fidelity subunit for DNA replication. |
Scheuermann R, Tam S, Burgers PM, Lu C, Echols H |
1983 |
| Replication protein A and proliferating cell nuclear antigen coordinate DNA polymerase selection in 8-oxo-guanine repair. |
Maga G, Crespan E, Wimmer U, van Loon B, Amoroso A, Mondello C, Belgiovine C, Ferrari E, Locatelli GA, Villani G, Hübscher U |
2008 |
| Limited terminal transferase in human DNA polymerase mu defines the required balance between accuracy and efficiency in NHEJ. |
Andrade P, Martín MJ, Juárez R, López de Saro F, Blanco L |
2009 |
| DNA polymerase accuracy and spontaneous mutation rates: frequencies of purine.purine, purine.pyrimidine, and pyrimidine.pyrimidine mismatches during DNA replication. |
Fersht AR, Knill-Jones JW |
1981 |
| In vitro evolution of terminal protein-containing genomes. |
Esteban JA, Blanco L, Villar L, Salas M |
1997 |
| A DNA polymerase alpha pause site is a hot spot for nucleotide misinsertion. |
Fry M, Loeb LA |
1992 |
| The carboxyl terminus of the bacteriophage T4 DNA polymerase is required for holoenzyme complex formation. |
Berdis AJ, Soumillion P, Benkovic SJ |
1996 |
| Detection of specific polymerase chain reaction product by utilizing the 5'----3' exonuclease activity of Thermus aquaticus DNA polymerase. |
Holland PM, Abramson RD, Watson R, Gelfand DH |
1991 |
| PCNA binding domains in all three subunits of yeast DNA polymerase {delta} modulate its function in DNA replication. |
Acharya N, Klassen R, Johnson RE, Prakash L, Prakash S |
2011 |
| Crystal structure of human immunodeficiency virus type 1 reverse transcriptase complexed with double-stranded DNA at 3.0 A resolution shows bent DNA. |
Jacobo-Molina A, Ding J, Nanni RG, Clark AD, Lu X, Tantillo C, Williams RL, Kamer G, Ferris AL, Clark PK |
1993 |
| Kinetic measurement of 2-aminopurine X cytosine and 2-aminopurine X thymine base pairs as a test of DNA polymerase fidelity mechanisms. |
Watanabe SM, Goodman MF |
1982 |
| Correlations between the activities of DNA polymerase alpha and the glucocorticoid receptor. |
Schmidt TJ, Bollum FJ, Litwack G |
1982 |
| Proofreading by DNA polymerase III of Escherichia coli depends on cooperative interaction of the polymerase and exonuclease subunits. |
Maki H, Kornberg A |
1987 |
| Abundant ribonucleotide incorporation into DNA by yeast replicative polymerases. |
Nick McElhinny SA, Watts BE, Kumar D, Watt DL, Lundström EB, Burgers PM, Johansson E, Chabes A, Kunkel TA |
2010 |
| Demonstration of a stimulatory protein for virus-specified DNA polymerase in phorbol ester-treated Epstein-Barr virus-carrying cells. |
Chiou JF, Li JK, Cheng YC |
1985 |
| Yeast Rev1 protein promotes complex formation of DNA polymerase zeta with Pol32 subunit of DNA polymerase delta. |
Acharya N, Johnson RE, Pagès V, Prakash L, Prakash S |
2009 |
| Cocrystal structure of an editing complex of Klenow fragment with DNA. |
Freemont PS, Friedman JM, Beese LS, Sanderson MR, Steitz TA |
1988 |
| DNA conformational changes at the primer-template junction regulate the fidelity of replication by DNA polymerase. |
Datta K, Johnson NP, von Hippel PH |
2010 |
| Identification of a higher molecular weight DNA polymerase alpha catalytic polypeptide in monkey cells by monoclonal antibody. |
Karawya E, Swack J, Albert W, Fedorko J, Minna JD, Wilson SH |
1984 |
| A cancer-associated DNA polymerase delta variant modeled in yeast causes a catastrophic increase in genomic instability. |
Daee DL, Mertz TM, Shcherbakova PV |
2010 |
| Archaeal eukaryote-like Orc1/Cdc6 initiators physically interact with DNA polymerase B1 and regulate its functions. |
Zhang L, Zhang L, Liu Y, Yang S, Gao C, Gong H, Feng Y, He ZG |
2009 |
| Efficient and accurate bypass of N2-(1-carboxyethyl)-2'-deoxyguanosine by DinB DNA polymerase in vitro and in vivo. |
Yuan B, Cao H, Jiang Y, Hong H, Wang Y |
2008 |
| Conformational transitions in DNA polymerase I revealed by single-molecule FRET. |
Santoso Y, Joyce CM, Potapova O, Le Reste L, Hohlbein J, Torella JP, Grindley ND, Kapanidis AN |
2010 |
| A heterodimeric DNA polymerase: evidence that members of Euryarchaeota possess a distinct DNA polymerase. |
Cann IK, Komori K, Toh H, Kanai S, Ishino Y |
1998 |
| Enzymatic joining of DNA strands: a novel reaction of diphosphopyridine nucleotide. |
Zimmerman SB, Little JW, Oshinsky CK, Gellert M |
1967 |
| Separation of the adenovirus terminal protein precursor from its associated DNA polymerase: role of both proteins in the initiation of adenovirus DNA replication. |
Lichy JH, Field J, Horwitz MS, Hurwitz J |
1982 |
| A type IB topoisomerase with DNA repair activities. |
Belova GI, Prasad R, Kozyavkin SA, Lake JA, Wilson SH, Slesarev AI |
2001 |
| Comparative properties of RNA and DNA templates for the DNA polymerase of Rous sarcoma virus. |
Duesberg P, Helm KV, Canaani E |
1971 |
| DNA polymerase alpha mutants from a Drosophila melanogaster cell line. |
Sugino A, Nakayama K |
1980 |
| Terminal protein-primed amplification of heterologous DNA with a minimal replication system based on phage {Phi}29. |
Mencía M, Gella P, Camacho A, de Vega M, Salas M |
2011 |
| DNA endonucleases associated with the avian myeloblastosis virus DNA polymerase. |
Samuel KP, Papas TS, Chirikjian JG |
1979 |
| Mechanism of nucleotide incorporation opposite a thymine-thymine dimer by yeast DNA polymerase eta. |
Washington MT, Prakash L, Prakash S |
2003 |
| Replication of duplex DNA by bacteriophage T7 DNA polymerase and gene 4 protein is accompanied by hydrolysis of nucleoside 5'-triphosphates. |
Kolodner R, Richardson CC |
1977 |
| ENZYMATIC SYNTHESIS OF DEOXYRIBONUCLEIC ACID. III. THE INCORPORATION OF PYRIMIDINE AND PURINE ANALOGUES INTO DEOXYRIBONUCLEIC ACID. |
Bessman MJ, Lehman IR, Adler J, Zimmerman SB, Simms ES, Kornberg A |
1958 |
| Mechanism of DNA polymerase II-mediated frameshift mutagenesis. |
Becherel OJ, Fuchs RP |
2001 |
| ENZYMATIC SYNTHESIS OF DEOXYRIBONUCLEIC ACID. IV. LINKAGE OF SINGLE DEOXYNUCLEOTIDES TO THE DEOXYNUCLEOSIDE ENDS OF DEOXYRIBONUCLEIC ACID. |
Adler J, Lehman IR, Bessman MJ, Simms ES, Kornberg A |
1958 |
| Genetic analysis of the interaction between bacteriophage T7 DNA polymerase and Escherichia coli thioredoxin. |
Himawan JS, Richardson CC |
1992 |
| Targeting of DNA polymerase to the adenovirus origin of DNA replication by interaction with nuclear factor I. |
Armentero MT, Horwitz M, Mermod N |
1994 |
| Ubiquitinated proliferating cell nuclear antigen activates translesion DNA polymerases eta and REV1. |
Garg P, Burgers PM |
2005 |
| A 5' to 3' exonuclease functionally interacts with calf DNA polymerase epsilon. |
Siegal G, Turchi JJ, Myers TW, Bambara RA |
1992 |
| DPB2, the gene encoding DNA polymerase II subunit B, is required for chromosome replication in Saccharomyces cerevisiae. |
Araki H, Hamatake RK, Johnston LH, Sugino A |
1991 |
| 3'-Azido-3'-deoxythymidine drug resistance mutations in HIV-1 reverse transcriptase can induce long range conformational changes. |
Ren J, Esnouf RM, Hopkins AL, Jones EY, Kirby I, Keeling J, Ross CK, Larder BA, Stuart DI, Stammers DK |
1998 |
| Effect of 3' flanking neighbors on kinetics of pairing of dCTP or dTTP opposite O6-methylguanine in a defined primed oligonucleotide when Escherichia coli DNA polymerase I is used. |
Singer B, Chavez F, Goodman MF, Essigmann JM, Dosanjh MK |
1989 |
| Directed evolution of polymerase function by compartmentalized self-replication. |
Ghadessy FJ, Ong JL, Holliger P |
2001 |
| A coupled complex of T4 DNA replication helicase (gp41) and polymerase (gp43) can perform rapid and processive DNA strand-displacement synthesis. |
Dong F, Weitzel SE, von Hippel PH |
1996 |
| Purification and characterization of the DNA polymerase of human breast cancer particles. |
Ohno T, Sweet RW, Dejak D, Spiegelman S |
1977 |
| Intracellular localization of mouse DNA polymerase-alpha. |
Herrick G, Spear BB, Veomett G |
1976 |
| Regulation of polymerase exchange between Poleta and Poldelta by monoubiquitination of PCNA and the movement of DNA polymerase holoenzyme. |
Zhuang Z, Johnson RE, Haracska L, Prakash L, Prakash S, Benkovic SJ |
2008 |
| Single-strand binding protein enhances fidelity of DNA synthesis in vitro. |
Kunkel TA, Meyer RR, Loeb LA |
1979 |
| A tumor necrosis factor alpha- and interleukin 6-inducible protein that interacts with the small subunit of DNA polymerase delta and proliferating cell nuclear antigen. |
He H, Tan CK, Downey KM, So AG |
2001 |
| Identification of a transient excision intermediate at the crossroads between DNA polymerase extension and proofreading pathways. |
Baker RP, Reha-Krantz LJ |
1998 |
| Protein affinity chromatography with purified yeast DNA polymerase alpha detects proteins that bind to DNA polymerase. |
Miles J, Formosa T |
1992 |
| Mismatch-specific 3'----5' exonuclease associated with the mitochondrial DNA polymerase from Drosophila embryos. |
Kaguni LS, Olson MW |
1989 |
| Hydrogen bonding revisited: geometric selection as a principal determinant of DNA replication fidelity. |
Goodman MF |
1997 |
| Rapid assembly of the bacteriophage T4 core replication complex on a linear primer/template construct. |
Kaboord BF, Benkovic SJ |
1993 |
| Interaction of the beta sliding clamp with MutS, ligase, and DNA polymerase I. |
López de Saro FJ, O'Donnell ME |
2001 |
| Analysis of mutations at positions 115 and 116 in the dNTP binding site of HIV-1 reverse transcriptase. |
Boyer PL, Sarafianos SG, Arnold E, Hughes SH |
2000 |
| Activity of the purified mutagenesis proteins UmuC, UmuD', and RecA in replicative bypass of an abasic DNA lesion by DNA polymerase III. |
Rajagopalan M, Lu C, Woodgate R, O'Donnell ME, Goodman MF, Echols H |
1992 |
| Pentaribonucleotides of mixed sequence are synthesized and efficiently prime de novo DNA chain starts in the T4 bacteriophage DNA replication system. |
Liu CC, Alberts BM |
1980 |
| Discrimination against purine-pyrimidine mispairs in the polymerase active site of DNA polymerase I: a structural explanation. |
Minnick DT, Liu L, Grindley ND, Kunkel TA, Joyce CM |
2002 |
| Detection and characterization of mammalian DNA polymerase beta mutants by functional complementation in Escherichia coli. |
Sweasy JB, Loeb LA |
1993 |
| Mammalian mutator mutant with an aphidicolin-resistant DNA polymerase alpha. |
Liu PK, Chang CC, Trosko JE, Dube DK, Martin GM, Loeb LA |
1983 |
| Promoters selected from random DNA sequences. |
Horwitz MS, Loeb LA |
1986 |
| Rearrangements of DNA mediated by terminal transferase. |
Kunkel TA, Gopinathan KP, Dube DK, Snow ET, Loeb LA |
1986 |
| Cyclin A activates the DNA polymerase delta -dependent elongation machinery in vitro: A parvovirus DNA replication model. |
Bashir T, Horlein R, Rommelaere J, Willwand K |
2000 |
| Fialuridine and its metabolites inhibit DNA polymerase gamma at sites of multiple adjacent analog incorporation, decrease mtDNA abundance, and cause mitochondrial structural defects in cultured hepatoblasts. |
Lewis W, Levine ES, Griniuviene B, Tankersley KO, Colacino JM, Sommadossi JP, Watanabe KA, Perrino FW |
1996 |
| Transposon Tn5 excision in yeast: influence of DNA polymerases alpha, delta, and epsilon and repair genes. |
Gordenin DA, Malkova AL, Peterzen A, Kulikov VN, Pavlov YI, Perkins E, Resnick MA |
1992 |
| Polymerase recognition of synthetic oligodeoxyribonucleotides incorporating degenerate pyrimidine and purine bases. |
Hill F, Loakes D, Brown DM |
1998 |
| Replication of UV-irradiated single-stranded DNA by DNA polymerase III holoenzyme of Escherichia coli: evidence for bypass of pyrimidine photodimers. |
Livneh Z |
1986 |
| Probable involvement of a glycoconjugate in IMR-32 DNA synthesis: decrease of DNA polymerase alpha 2 activity after tunicamycin treatment. |
Bhattacharya P, Basu S |
1982 |
| DNA polymerase delta from embryos of Drosophila melanogaster. |
Chiang CS, Mitsis PG, Lehman IR |
1993 |
| A cryptic proofreading 3'----5' exonuclease associated with the polymerase subunit of the DNA polymerase-primase from Drosophila melanogaster. |
Cotterill SM, Reyland ME, Loeb LA, Lehman IR |
1987 |
| Mechanism of elongation of primed DNA by DNA polymerase delta, proliferating cell nuclear antigen, and activator 1. |
Lee SH, Hurwitz J |
1990 |
| Crystal structure of a benzo[a]pyrene diol epoxide adduct in a ternary complex with a DNA polymerase. |
Ling H, Sayer JM, Plosky BS, Yagi H, Boudsocq F, Woodgate R, Jerina DM, Yang WW |
2004 |
| Structure of a small-molecule inhibitor of a DNA polymerase sliding clamp. |
Georgescu RE, Yurieva O, Kim SS, Kuriyan J, Kong XP, O'Donnell ME |
2008 |
| Functional roles of DNA polymerases beta and gamma. |
Hübscher U, Kuenzle CC, Spadari S |
1979 |
| Crystal structure of DNA-bound Co(III) bleomycin B2: Insights on intercalation and minor groove binding. |
Goodwin KD, Lewis MA, Long EC, Georgiadis MM |
2008 |
| Absolute configuration of the diastereomers of adenosine 5'-O-(1-thiotriphosphate): consequences for the stereochemistry of polymerization by DNA-dependent RNA polymerase from Escherichia coli. |
Burgers PM, Eckstein F |
1978 |
| Requirement of proliferating cell nuclear antigen in RAD6-dependent postreplicational DNA repair. |
Torres-Ramos CA, Yoder BL, Burgers PM, Prakash S, Prakash L |
1996 |
| What a difference a decade makes: insights into translesion DNA synthesis. |
Yang WW, Woodgate R |
2007 |
| Multiple point mutations in a shuttle vector propagated in human cells: evidence for an error-prone DNA polymerase activity. |
Seidman MM, Bredberg A, Seetharam S, Kraemer KH |
1987 |
| Specificity and efficiency of editing of mismatches involved in the formation of base-substitution mutations by the 3'----5' exonuclease activity of phage T4 DNA polymerase. |
Sinha NK |
1987 |
| A single side chain prevents Escherichia coli DNA polymerase I (Klenow fragment) from incorporating ribonucleotides. |
Astatke M, Ng K, Grindley ND, Joyce CM |
1998 |
| Expression of DNA polymerase {beta} cancer-associated variants in mouse cells results in cellular transformation. |
Sweasy JB, Lang T, Starcevic D, Sun KW, Lai CC, Dimaio D, Dalal S |
2005 |
| Reduced in vivo mutagenesis by mutant herpes simplex DNA polymerase involves improved nucleotide selection. |
Hall JD, Furman PA, St Clair MH, Knopf CW |
1985 |
| Mammalian DNA polymerase alpha holoenzymes with possible functions at the leading and lagging strand of the replication fork. |
Ottiger HP, Hübscher U |
1984 |
| Synthesis of DNA containing the simian virus 40 origin of replication by the combined action of DNA polymerases alpha and delta. |
Lee SH, Eki T, Hurwitz J |
1989 |
| Incorporation into DNA of the base analog 2-aminopurine by the Epstein-Barr virus-induced DNA polymerase in vivo and in vitro. |
Grossberger D, Clough W |
1981 |
| The enzymological basis for resistance of herpesvirus DNA polymerase mutants to acyclovir: relationship to the structure of alpha-like DNA polymerases. |
Huang L, Ishii KK, Zuccola H, Gehring AM, Hwang CB, Hogle J, Coen DM |
1999 |
| The beta subunit sliding DNA clamp is responsible for unassisted mutagenic translesion replication by DNA polymerase III holoenzyme. |
Tomer G, Reuven NB, Livneh Z |
1998 |
| DNA nick processing by exonuclease and polymerase activities of bacteriophage T4 DNA polymerase accounts for acridine-induced mutation specificities in T4. |
Kaiser VL, Ripley LS |
1995 |
| Creating a dynamic picture of the sliding clamp during T4 DNA polymerase holoenzyme assembly by using fluorescence resonance energy transfer. |
Trakselis MA, Alley SC, Abel-Santos E, Benkovic SJ |
2001 |
| Structure of the binding site for nonnucleoside inhibitors of the reverse transcriptase of human immunodeficiency virus type 1. |
Smerdon SJ, Jäger J, Wang J, Kohlstaedt LA, Chirino AJ, Friedman JM, Rice PA, Steitz TA |
1994 |
| The replicative DNA polymerase of herpes simplex virus 1 exhibits apurinic/apyrimidinic and 5'-deoxyribose phosphate lyase activities. |
Bogani F, Boehmer PE |
2008 |
| Use of DNA polymerase I primed by a synthetic oligonucleotide to determine a nucleotide sequence in phage fl DNA. |
Sanger F, Donelson JE, Coulson AR, Kössel H, Fischer D |
1973 |
| Single molecule measurement of the "speed limit" of DNA polymerase. |
Schwartz JJ, Quake SR |
2009 |
| DNA polymerase active site is highly mutable: evolutionary consequences. |
Patel PH, Loeb LA |
2000 |
| An antiviral target on reverse transcriptase of human immunodeficiency virus type 1 revealed by tetrahydroimidazo-[4,5,1-jk] [1,4]benzodiazepin-2 (1H)-one and -thione derivatives. |
Debyser Z, Pauwels R, Andries K, Desmyter J, Kukla M, Janssen PA, De Clercq E |
1991 |
| Construction of biologically functional bacterial plasmids in vitro. |
Cohen SN, Chang AC, Boyer HW, Helling RB |
1973 |
| Structure of HIV-2 reverse transcriptase at 2.35-A resolution and the mechanism of resistance to non-nucleoside inhibitors. |
Ren J, Bird LE, Chamberlain PP, Stewart-Jones GB, Stuart DI, Stammers DK |
2002 |
| The thioredoxin binding domain of bacteriophage T7 DNA polymerase confers processivity on Escherichia coli DNA polymerase I. |
Bedford E, Tabor S, Richardson CC |
1997 |
| Participation of mouse DNA polymerase iota in strand-biased mutagenic bypass of UV photoproducts and suppression of skin cancer. |
Dumstorf CA, Clark AB, Lin Q, Kissling GE, Yuan T, Kucherlapati R, McGregor WG, Kunkel TA |
2006 |
| Affinity purification of bacteriophage T4 proteins essential for DNA replication and genetic recombination. |
Formosa T, Burke RL, Alberts BM |
1983 |
| Bacterial and phage mutations that reveal helix-unwinding activities required for bacteriophage T4 DNA replication. |
Gauss P, Doherty DH, Gold L |
1983 |
| Probing the active site tightness of DNA polymerase in subangstrom increments. |
Kim TW, Delaney JC, Essigmann JM, Kool ET |
2005 |
| Accessory proteins for DNA polymerase alpha activity with single-strand DNA templates. |
Lamothe P, Baril B, Chi A, Lee L, Baril E |
1981 |
| A DNA primase activity associated with DNA polymerase alpha from Drosophila melanogaster embryos. |
Conaway RC, Lehman IR |
1982 |
| Diadenosine 5',5'''-P1,P4-tetraphosphate, a ligand of the 57-kilodalton subunit of DNA polymerase alpha. |
Grummt F, Waltl G, Jantzen HM, Hamprecht K, Huebscher U, Kuenzle CC |
1979 |
| Stationary-phase mutation in the bacterial chromosome: recombination protein and DNA polymerase IV dependence. |
Bull HJ, Lombardo MJ, Rosenberg SM |
2001 |
| Crystal structure of Taq DNA polymerase in complex with an inhibitory Fab: the Fab is directed against an intermediate in the helix-coil dynamics of the enzyme. |
Murali R, Sharkey DJ, Daiss JL, Murthy HM |
1998 |
| Two distinct modes of RecA action are required for DNA polymerase V-catalyzed translesion synthesis. |
Pham P, Seitz EM, Saveliev S, Shen X, Woodgate R, Cox MM, Goodman MF |
2002 |
| Quantitative measurement of translesion replication in human cells: evidence for bypass of abasic sites by a replicative DNA polymerase. |
Avkin S, Adar S, Blander G, Livneh Z |
2002 |
| Molecular analysis of mutations in DNA polymerase eta in xeroderma pigmentosum-variant patients. |
Broughton BC, Cordonnier AM, Kleijer WJ, Jaspers NG, Fawcett H, Raams A, Garritsen VH, Stary A, Avril MF, Boudsocq F, Masutani C, Hanaoka F, Fuchs RP, Sarasin A, Lehmann AR |
2002 |
| Long-term inhibition of human T-lymphotropic virus type III/lymphadenopathy-associated virus (human immunodeficiency virus) DNA synthesis and RNA expression in T cells protected by 2',3'-dideoxynucleosides in vitro. |
Mitsuya H, Jarrett RF, Matsukura M, di Marzo Veronese F, DeVico AL, Sarngadharan MG, Johns DG, Reitz MS, Broder S |
1987 |
| Broad spectrum of in vivo forward mutations, hypermutations, and mutational hotspots in a retroviral shuttle vector after a single replication cycle: deletions and deletions with insertions. |
Pathak VK, Temin HM |
1990 |
| The C-terminal region of Schizosaccaromyces pombe proliferating cell nuclear antigen is essential for DNA polymerase activity. |
Kelman Z, Zuo S, Arroyo MP, Wang TS, Hurwitz J |
1999 |
| DNA sequencing with chain-terminating inhibitors. |
Sanger F, Nicklen S, Coulson AR |
1977 |
| Copy-choice recombination mediated by DNA polymerase III holoenzyme from Escherichia coli. |
Canceill D, Ehrlich SD |
1996 |
| Interaction of herpes simplex virus 1 origin-binding protein with DNA polymerase alpha. |
Lee SS, Dong Q, Wang TS, Lehman IR |
1995 |
| DNA polymerase of bacteriophage T4 is an autogenous translational repressor. |
Andrake M, Guild N, Hsu T, Gold L, Tuerk C, Karam J |
1988 |
| Targeted gene evolution in Escherichia coli using a highly error-prone DNA polymerase I. |
Camps M, Naukkarinen J, Johnson BP, Loeb LA |
2003 |
| Functions of replication factor C and proliferating-cell nuclear antigen: functional similarity of DNA polymerase accessory proteins from human cells and bacteriophage T4. |
Tsurimoto T, Stillman B |
1990 |
| Okazaki fragment processing: modulation of the strand displacement activity of DNA polymerase delta by the concerted action of replication protein A, proliferating cell nuclear antigen, and flap endonuclease-1. |
Maga G, Villani G, Tillement V, Stucki M, Locatelli GA, Frouin I, Spadari S, Hübscher U |
2001 |
| Specific inhibition of herpes simplex virus DNA polymerase by helical peptides corresponding to the subunit interface. |
Digard P, Williams KP, Hensley P, Brooks IS, Dahl CE, Coen DM |
1995 |
| High incidence of epithelial cancers in mice deficient for DNA polymerase delta proofreading. |
Goldsby RE, Hays LE, Chen X, Olmsted EA, Slayton WB, Spangrude GJ, Preston BD |
2002 |
| An 8-oxo-guanine repair pathway coordinated by MUTYH glycosylase and DNA polymerase lambda. |
van Loon B, Hübscher U |
2009 |
| Cdk-interacting protein 1 directly binds with proliferating cell nuclear antigen and inhibits DNA replication catalyzed by the DNA polymerase delta holoenzyme. |
Flores-Rozas H, Kelman Z, Dean FB, Pan ZQ, Harper JW, Elledge SJ, O'Donnell ME, Hurwitz J |
1994 |
| Human immunodeficiency virus reverse transcriptase substitutes for DNA polymerase I in Escherichia coli. |
Kim B, Loeb LA |
1995 |
| Recombination hotspots in bacteriophage T4 are dependent on replication origins. |
Yap WY, Kreuzer KN |
1991 |
| Structure-based design of Taq DNA polymerases with improved properties of dideoxynucleotide incorporation. |
Li Y, Mitaxov V, Waksman G |
1999 |
| Stimulation of human neuroblastoma DNA polymerase alpha and primase activities by a protein factor isolated from rat liver chromatin. |
Takada S, Torres-Rosado A, Ray S, Basu S |
1986 |
| Inhibition of human neuroblastoma DNA polymerase activities by plant lectins and toxins. |
Bhattacharya P, Simet I, Basu S |
1979 |
| Purification and DNA synthesis in cell-free extracts: properties of DNA polymerase II. |
Kornberg T, Gefter ML |
1971 |
| DNA polymerase delta is required for base excision repair of DNA methylation damage in Saccharomyces cerevisiae. |
Blank A, Kim B, Loeb LA |
1994 |
| Accuracy of thymine-thymine dimer bypass by Saccharomyces cerevisiae DNA polymerase eta. |
Washington MT, Johnson RE, Prakash S, Prakash L |
2000 |
| Escherichia coli DnaX product, the tau subunit of DNA polymerase III, is a multifunctional protein with single-stranded DNA-dependent ATPase activity. |
Lee SH, Walker JR |
1987 |
| The dynamic processivity of the T4 DNA polymerase during replication. |
Yang J, Zhuang Z, Roccasecca RM, Trakselis MA, Benkovic SJ |
2004 |
| Generation of single-stranded DNA by the polymerase chain reaction and its application to direct sequencing of the HLA-DQA locus. |
Gyllensten UB, Erlich HA |
1988 |
| Priming of DNA synthesis by diadenosine 5',5"'-P1,P4-tetraphosphate with a double-stranded octadecamer as a template and DNA polymerase alpha. |
Zamecnik PC, Rapaport E, Baril EF |
1982 |
| Removal of polymerase-produced mutant sequences from PCR products. |
Smith J, Modrich P |
1997 |
| Proliferating cell nuclear antigen promotes DNA synthesis past template lesions by mammalian DNA polymerase delta. |
Mozzherin DJ, Shibutani S, Tan CK, Downey KM, Fisher PA |
1997 |
| Effect of manganese ions on the incorporation of dideoxynucleotides by bacteriophage T7 DNA polymerase and Escherichia coli DNA polymerase I. |
Tabor S, Richardson CC |
1989 |
| Escherichia coli thioredoxin: a subunit of bacteriophage T7 DNA polymerase. |
Mark DF, Richardson CC |
1976 |
| In search of a mutational hotspot. |
Hatahet Z, Zhou M, Reha-Krantz LJ, Morrical SW, Wallace SS |
1998 |
| Retention of replication fidelity by a DNA polymerase functioning in a distantly related environment. |
Dressman HK, Wang CC, Karam JD, Drake JW |
1997 |
| Heat mutagenesis in bacteriophage T4: the transversion pathway. |
Bingham PM, Baltz RH, Ripley LS, Drake JW |
1976 |
| Distinct mechanisms of cis-syn thymine dimer bypass by Dpo4 and DNA polymerase eta. |
Johnson RE, Prakash L, Prakash S |
2005 |
| Bridging the gap: a family of novel DNA polymerases that replicate faulty DNA. |
Johnson RE, Washington MT, Prakash S, Prakash L |
1999 |
| Mechanism of DNA polymerase I: exonuclease/polymerase activity switch and DNA sequence dependence of pyrophosphorolysis and misincorporation reactions. |
Mizrahi V, Benkovic P, Benkovic SJ |
1986 |
| A DNA-binding protein induced by bacteriophage T7. |
Reuben RC, Gefter ML |
1973 |
| Improvement of phi29 DNA polymerase amplification performance by fusion of DNA binding motifs. |
de Vega M, Lázaro JM, Mencía M, Blanco L, Salas M |
2010 |
| DNA polymerase eta lacking the ubiquitin-binding domain promotes replicative lesion bypass in humans cells. |
Acharya N, Yoon JH, Hurwitz J, Prakash L, Prakash S |
2010 |
| PCR amplification of up to 35-kb DNA with high fidelity and high yield from lambda bacteriophage templates. |
Barnes WM |
1994 |
| Mechanism of carcinogenesis by RNA tumor viruses. 3. Formation of RNA, DNA complex and duplex DNA molecules by the DNA polymerase (s) of avian myeloblastosis virus. |
Fujinaga K, Parsons JT, Beard JW, Beard D, Green M |
1970 |
| Replication of phage phi 29 DNA with purified terminal protein and DNA polymerase: synthesis of full-length phi 29 DNA. |
Blanco L, Salas M |
1985 |
| Initiation of phage phi 29 DNA replication in vitro: formation of a covalent complex between the terminal protein, p3, and 5'-dAMP. |
Peñalva MA, Salas M |
1982 |
| Structure of DNA polymerase beta with a benzo[c]phenanthrene diol epoxide-adducted template exhibits mutagenic features. |
Batra VK, Shock DD, Prasad R, Beard WA, Hou EW, Pedersen LC, Sayer JM, Yagi H, Kumar S, Jerina DM, Wilson SH |
2006 |
| High-resolution structures of HIV-1 reverse transcriptase/TMC278 complexes: strategic flexibility explains potency against resistance mutations. |
Das K, Bauman JD, Clark AD, Frenkel YV, Lewi PJ, Shatkin AJ, Hughes SH, Arnold E |
2008 |
| DNA polymerase III of Escherichia coli is required for UV and ethyl methanesulfonate mutagenesis. |
Hagensee ME, Timme TL, Bryan SK, Moses RE |
1987 |
| Nucleotide-dependent conformational change governs specificity and analog discrimination by HIV reverse transcriptase. |
Kellinger MW, Johnson KA |
2010 |
| Synthesis of parvovirus H-1 replicative form from viral DNA by DNA polymerase gamma. |
Kollek R, Goulian M |
1981 |
| DNA polymerase epsilon is required for coordinated and efficient chromosomal DNA replication in Xenopus egg extracts. |
Waga S, Masuda T, Takisawa H, Sugino A |
2001 |
| Replication infidelity via a mismatch with Watson-Crick geometry. |
Bebenek K, Pedersen LC, Kunkel TA |
2011 |
| Architecture of the DNA polymerase B-proliferating cell nuclear antigen (PCNA)-DNA ternary complex. |
Mayanagi K, Kiyonari S, Nishida H, Saito M, Kohda D, Ishino Y, Shirai T, Morikawa K |
2011 |
| Conferring RNA polymerase activity to a DNA polymerase: a single residue in reverse transcriptase controls substrate selection. |
Gao G, Orlova M, Georgiadis MM, Hendrickson WA, Goff SP |
1997 |
| DNA sequencing with Thermus aquaticus DNA polymerase and direct sequencing of polymerase chain reaction-amplified DNA. |
Innis MA, Myambo KB, Gelfand DH, Brow MA |
1988 |
| Mechanism of resistance of human immunodeficiency virus type 1 to 2',3'-dideoxyinosine. |
Martin JL, Wilson JE, Haynes RL, Furman PA |
1993 |
| DNA strand breaking by the hydroxyl radical is governed by the accessible surface areas of the hydrogen atoms of the DNA backbone. |
Balasubramanian B, Pogozelski WK, Tullius TD |
1998 |
| Replication of bacteriophage phi 29 DNA in vitro: the roles of terminal protein and DNA polymerase. |
Watabe K, Leusch M, Ito J |
1984 |
| RNA virus error catastrophe: direct molecular test by using ribavirin. |
Crotty S, Cameron CE, Andino R |
2001 |
| Mutagenic DNA polymerase in human leukemic cells. |
Springgate CF, Loeb LA |
1973 |
| Lamivudine (3TC) resistance in HIV-1 reverse transcriptase involves steric hindrance with beta-branched amino acids. |
Sarafianos SG, Das K, Clark AD, Ding J, Boyer PL, Hughes SH, Arnold E |
1999 |
| Unblocking of chain-terminated primer by HIV-1 reverse transcriptase through a nucleotide-dependent mechanism. |
Meyer PR, Matsuura SE, So AG, Scott WA |
1998 |
| The ATF/CREB transcription factor-binding site in the polymerase beta promoter mediates the positive effect of N-methyl-N'-nitro-N-nitrosoguanidine on transcription. |
Kedar PS, Widen SG, Englander EW, Fornace AJ, Wilson SH |
1991 |
| Frameshift mutations produced by proflavin in bacteriophage T4: specificity within a hotspot. |
Ripley LS, Clark A |
1986 |
| Conformational dynamics of bacteriophage T7 DNA polymerase and its processivity factor, Escherichia coli thioredoxin. |
Akabayov B, Akabayov SR, Lee SJ, Tabor S, Kulczyk AW, Richardson CC |
2010 |
| Primary structure of the catalytic subunit of human DNA polymerase delta and chromosomal location of the gene. |
Chung DW, Zhang JA, Tan CK, Davie EW, So AG, Downey KM |
1991 |
| A DNA polymerase beta mutant from colon cancer cells induces mutations. |
Lang T, Maitra M, Starcevic D, Li SX, Sweasy JB |
2004 |
| Molecular matchmaking: NNRTIs can enhance the dimerization of HIV type 1 reverse transcriptase. |
Hughes SH |
2001 |
| Structural origins of the exonuclease resistance of a zwitterionic RNA. |
Teplova M, Wallace ST, Tereshko V, Minasov G, Symons AM, Cook PD, Manoharan M, Egli M |
1999 |
| Mutations in the RNase H domain of HIV-1 reverse transcriptase affect the initiation of DNA synthesis and the specificity of RNase H cleavage in vivo. |
Julias JG, McWilliams MJ, Sarafianos SG, Arnold E, Hughes SH |
2002 |
| Reconstruction of bacteriophage T4 DNA replication apparatus from purified components: rolling circle replication following de novo chain initiation on a single-stranded circular DNA template. |
Morris CF, Sinha NK, Alberts BM |
1975 |
| In vitro DNA replication of recombinant plasmid DNAs containing the origin of progeny replicative form DNA synthesis of phage phi X174. |
Zipursky SL, Reinberg D, Hurwitz J |
1980 |
| Mechanism of the idling-turnover reaction of the large (Klenow) fragment of Escherichia coli DNA polymerase I. |
Mizrahi V, Benkovic PA, Benkovic SJ |
1986 |
| Crystal structure of a thermostable type B DNA polymerase from Thermococcus gorgonarius. |
Hopfner KP, Eichinger A, Engh RA, Laue F, Ankenbauer W, Huber R, Angerer B |
1999 |
| Two proton transfers in the transition state for nucleotidyl transfer catalyzed by RNA- and DNA-dependent RNA and DNA polymerases. |
Castro C, Smidansky ED, Maksimchuk KR, Arnold JJ, Korneeva VS, Götte M, Konigsberg WH, Cameron CE |
2007 |
| Adriamycin and daunorubicin inhibition of mutant T4 DNA polymerases. |
Goodman MF, Bessman MJ, Bachur NR |
1974 |
| DNA sequence analysis with a modified bacteriophage T7 DNA polymerase. |
Tabor S, Richardson CC |
1987 |
| Effect of DNA polymerase I and DNA helicase II on the turnover rate of UvrABC excision nuclease. |
Husain I, Van Houten B, Thomas DC, Abdel-Monem M, Sancar A |
1985 |
| Energy analysis of chemistry for correct insertion by DNA polymerase beta. |
Lin P, Pedersen LC, Batra VK, Beard WA, Wilson SH, Pedersen LG |
2006 |
| Nonnucleoside reverse transcriptase inhibitors are chemical enhancers of dimerization of the HIV type 1 reverse transcriptase. |
Tachedjian G, Orlova M, Sarafianos SG, Arnold E, Goff SP |
2001 |
| HeLa cell DNA polymerase alpha is tightly associated with tryptophanyl-tRNA synthetase and diadenosine 5',5"'-P1,P4-tetraphosphate binding activities. |
Rapaport E, Zamecnik PC, Baril EF |
1981 |
| The structural basis for the mutagenicity of O(6)-methyl-guanine lesions. |
Warren JJ, Forsberg LJ, Beese LS |
2006 |
| In vitro bypass of UV-induced lesions by Escherichia coli DNA polymerase I: specificity of nucleotide incorporation. |
Rabkin SD, Moore PD, Strauss BS |
1983 |
| A new synthetic RNA-dependent DNA polymerase from human tissue culture cells (HeLa-fibroblast-synthetic oligonucleotides-template-purified enzymes). |
Fridlender B, Fry M, Bolden A, Weissbach A |
1972 |
| Assembly of a functional replication complex without ATP hydrolysis: a direct interaction of bacteriophage T4 gp45 with T4 DNA polymerase. |
Reddy MK, Weitzel SE, von Hippel PH |
1993 |
| Structural determinant for switching between the polymerase and exonuclease modes in the PCNA-replicative DNA polymerase complex. |
Nishida H, Mayanagi K, Kiyonari S, Sato Y, Oyama T, Ishino Y, Morikawa K |
2009 |
| Multiple functions of human single-stranded-DNA binding protein in simian virus 40 DNA replication: single-strand stabilization and stimulation of DNA polymerases alpha and delta. |
Kenny MK, Lee SH, Hurwitz J |
1989 |
| The human DINB1 gene encodes the DNA polymerase Poltheta. |
Johnson RE, Prakash S, Prakash L |
2000 |
| DNA polymerases alpha, delta, and epsilon: three distinct enzymes from HeLa cells. |
Syväoja J, Suomensaari S, Nishida C, Goldsmith JS, Chui GS, Jain S, Linn S |
1990 |
| Macromolecular crowding increases binding of DNA polymerase to DNA: an adaptive effect. |
Zimmerman SB, Harrison B |
1987 |
| Emergence of human immunodeficiency virus type 1 variants with resistance to multiple dideoxynucleosides in patients receiving therapy with dideoxynucleosides. |
Shirasaka T, Kavlick MF, Ueno T, Gao WY, Kojima E, Alcaide ML, Chokekijchai S, Roy BM, Arnold E, Yarchoan R |
1995 |
| Separation of deoxyribo-oligonucleotidases induced by infection with bacteriophage T2. |
Short EC, Koerner JF |
1965 |
| Induction of DNA polymerase in human lymphocytes by phytohemagglutinin. |
Loeb LA, Agarwal SS, Woodside AM |
1968 |
| Clusters of mutations from transient hypermutability. |
Drake JW, Bebenek A, Kissling GE, Peddada S |
2005 |
| Characterization of a temperature-sensitive mutant of mouse FM3A cells defective in DNA replication. |
Murakami Y, Yasuda H, Miyazawa H, Hanaoka F, Yamada M |
1985 |
| Mutator strains of Escherichia coli, mutD and dnaQ, with defective exonucleolytic editing by DNA polymerase III holoenzyme. |
Echols H, Lu C, Burgers PM |
1983 |
| Linkage of polynucleotides through phosphodiester bonds by an enzyme from Escherichia coli. |
Olivera BM, Lehman IR |
1967 |
| Human DNA polymerase eta activity and translocation is regulated by phosphorylation. |
Chen YW, Cleaver JE, Hatahet Z, Honkanen RE, Chang JY, Yen Y, Chou KM |
2008 |
| Open clamp structure in the clamp-loading complex visualized by electron microscopic image analysis. |
Miyata T, Suzuki H, Oyama T, Mayanagi K, Ishino Y, Morikawa K |
2005 |
| Yeast DNA polymerase eta makes functional contacts with the DNA minor groove only at the incoming nucleoside triphosphate. |
Washington MT, Wolfle WT, Spratt TE, Prakash L, Prakash S |
2003 |
| The yeast analog of mammalian cyclin/proliferating-cell nuclear antigen interacts with mammalian DNA polymerase delta. |
Bauer GA, Burgers PM |
1988 |
| Exonuclease VI, a new nuclease activity associated with E. coli DNA polymerase. |
Klett RP, Cerami A, Reich E |
1968 |
| The structure of unliganded reverse transcriptase from the human immunodeficiency virus type 1. |
Rodgers DW, Gamblin SJ, Harris BA, Ray S, Culp JS, Hellmig B, Woolf DJ, Debouck C, Harrison SC |
1995 |
| Human immunodeficiency virus reverse transcriptase substrate-induced conformational changes and the mechanism of inhibition by nonnucleoside inhibitors. |
Rittinger K, Divita G, Goody RS |
1995 |
| Characterization and purification of a phage phi 29-encoded DNA polymerase required for the initiation of replication. |
Blanco L, Salas M |
1984 |
| Single-molecule and ensemble fluorescence assays for a functionally important conformational change in T7 DNA polymerase. |
Luo G, Wang M, Konigsberg WH, Xie XS |
2007 |
| Studies on in vitro DNA synthesis. Purification of the dna G gene product from Escherichia coli. |
Wickner S, Wright M, Hurwitz J |
1973 |
| Accuracy of lesion bypass by yeast and human DNA polymerase eta. |
Washington MT, Johnson RE, Prakash L, Prakash S |
2001 |
| Effects of different DNA polymerases in ligation-mediated PCR: enhanced genomic sequencing and in vivo footprinting. |
Garrity PA, Wold BJ |
1992 |
| A bacteriophage T7 RNA polymerase/promoter system for controlled exclusive expression of specific genes. |
Tabor S, Richardson CC |
1985 |
| Selective elimination of the exonuclease activity of the deoxyribonucleic acid polymerase from Escherichia coli B by limited proteolysis. |
Klenow H, Henningsen I |
1970 |
| DNA primase activity associated with DNA polymerase alpha from Xenopus laevis ovaries. |
Shioda M, Nelson EM, Bayne ML, Benbow RM |
1982 |
| The structural gene for deoxyribonucleic acid polymerase in bacteriophages T4 and T5. |
De Waard A, Paul AV, Lehman IR |
1965 |
| Absence of RNase H allows replication of pBR322 in Escherichia coli mutants lacking DNA polymerase I. |
Kogoma T |
1984 |
| Formation of covalent circles of lambda DNA by E. coli extracts. |
Gellert M |
1967 |
| Cell-free cloning using phi29 DNA polymerase. |
Hutchison CA, Smith HO, Pfannkoch C, Venter JC |
2005 |
| Decreased fidelity of DNA polymerase activity during N-2-fluorenylacetamide hepatocarcinogenesis. |
Chan JY, Becker FF |
1979 |
| The accessory subunit of DNA polymerase gamma is essential for mitochondrial DNA maintenance and development in Drosophila melanogaster. |
Iyengar B, Luo N, Farr CL, Kaguni LS, Campos AR |
2002 |
| Fidelity of replication of phage phi X174 DNA by DNA polymerase III holoenzyme: spontaneous mutation by misincorporation. |
Fersht AR |
1979 |
| Differential inhibition of multiple forms of DNA polymerase alpha from IMR-32 human neuroblastoma cells. |
Bhattacharya P, Simet I, Basu S |
1981 |
| The enzymatic termination of polydeoxynucleotides by 2',3'-dideoxyadenosine triphosphate. |
Toji L, Cohen SS |
1969 |
| Enzymatic breakage and joining of deoxyribonucleic acid, I. Repair of single-strand breaks in DNA by an enzyme system from Escherichia coli infected with T4 bacteriophage. |
Weiss B, Richardson CC |
1967 |
| Thioredoxin suppresses microscopic hopping of T7 DNA polymerase on duplex DNA. |
Etson CM, Hamdan SM, Richardson CC, van Oijen AM |
2010 |
| Highly error-free role of DNA polymerase eta in the replicative bypass of UV-induced pyrimidine dimers in mouse and human cells. |
Yoon JH, Prakash L, Prakash S |
2009 |
| DNA polymerase zeta cooperates with polymerases kappa and iota in translesion DNA synthesis across pyrimidine photodimers in cells from XPV patients. |
Ziv O, Geacintov NE, Nakajima S, Yasui A, Livneh Z |
2009 |
| Cell-free synthesis of the precursor polypeptide for avian myeloblastosis virus DNA polymerase. |
Paterson BM, Marciani DJ, Papas TS |
1977 |
| A unique loop in T7 DNA polymerase mediates the binding of helicase-primase, DNA binding protein, and processivity factor. |
Hamdan SM, Marintcheva B, Cook TE, Lee SJ, Tabor S, Richardson CC |
2005 |
| Template-directed pausing in in vitro DNA synthesis by DNA polymerase a from Drosophila melanogaster embryos. |
Kaguni LS, Clayton DA |
1982 |
| Isolation of a herpesvirus-specific DNA polymerase from tissues of an American patient with Burkitt lymphoma. |
Allaudeen HS, Bertino JR |
1978 |
| Single-molecule measurements of synthesis by DNA polymerase with base-pair resolution. |
Christian TD, Romano LJ, Rueda D |
2009 |
| Roles of PCNA-binding and ubiquitin-binding domains in human DNA polymerase eta in translesion DNA synthesis. |
Acharya N, Yoon JH, Gali H, Unk I, Haracska L, Johnson RE, Hurwitz J, Prakash L, Prakash S |
2008 |
| Rolling circle DNA replication in vitro by a complex of herpes simplex virus type 1-encoded enzymes. |
Skaliter R, Lehman IR |
1994 |
| Posttranslational modification of the umuD-encoded subunit of Escherichia coli DNA polymerase V regulates its interactions with the beta processivity clamp. |
Sutton MD, Narumi I, Walker GC |
2002 |
| Recombinational bypass of pyrimidine dimers promoted by the recA protein of Escherichia coli. |
Livneh Z, Lehman IR |
1982 |
| A variant of DNA polymerase beta acts as a dominant negative mutant. |
Bhattacharyya N, Banerjee S |
1997 |
| Dpb11, which interacts with DNA polymerase II(epsilon) in Saccharomyces cerevisiae, has a dual role in S-phase progression and at a cell cycle checkpoint. |
Araki H, Leem SH, Phongdara A, Sugino A |
1995 |
| ENZYMATIC SYNTHESIS OF DEOXYRIBONUCLEIC ACID. V. CHEMICAL COMPOSITION OF ENZYMATICALLY SYNTHESIZED DEOXYRIBONUCLEIC ACID. |
Lehman IR, Zimmerman SB, Adler J, Bessman MJ, Simms ES, Kornberg A |
1958 |
| Multiple forms of DNA polymerase in mouse myeloma. |
Matsukage A, Bohn EW, Wilson SH |
1974 |
| A novel DNA polymerase activity found in association with intracisternal A-type particles. |
Wilson SH, Kuff EL |
1972 |
| Differential correction of lagging-strand replication errors made by DNA polymerases {alpha} and {delta}. |
Nick McElhinny SA, Kissling GE, Kunkel TA |
2010 |
| Fidelity of a human cell DNA replication complex. |
Roberts JD, Kunkel TA |
1988 |
| Initiation of phi 29 DNA replication occurs at the second 3' nucleotide of the linear template: a sliding-back mechanism for protein-primed DNA replication. |
Méndez J, Blanco L, Esteban JA, Bernad A, Salas M |
1992 |
| Optimization of DNA polymerase mutation rates during bacterial evolution. |
Loh E, Salk JJ, Loeb LA |
2010 |
| Bacteriophage T7 gene 2.5 protein: an essential protein for DNA replication. |
Kim YT, Richardson CC |
1993 |
| Two-dimensional infrared spectra reveal relaxation of the nonnucleoside inhibitor TMC278 complexed with HIV-1 reverse transcriptase. |
Fang C, Bauman JD, Das K, Remorino A, Arnold E, Hochstrasser RM |
2008 |
| Template recognition sequence for RNA primer synthesis by gene 4 protein of bacteriophage T7. |
Tabor S, Richardson CC |
1981 |
| Isolation of a specialized transducing bacteriophage lambda carrying the polC locus of Escherichia coli. |
Shizuya H, Livingston DM, Richardson CC |
1974 |
| Isolation and partial characterization of a mutant of Escherichia coli deficient in DNA polymerase II. |
Campbell JL, Soll L, Richardson CC |
1972 |
| Expression of soluble, enzymatically active, human immunodeficiency virus reverse transcriptase in Escherichia coli and analysis of mutants. |
Hizi A, McGill C, Hughes SH |
1988 |
| Structural basis for the synthesis of nucleobase modified DNA by Thermus aquaticus DNA polymerase. |
Obeid S, Baccaro A, Welte W, Diederichs K, Marx A |
2010 |
| Leading and lagging strand DNA synthesis in vitro by a reconstituted herpes simplex virus type 1 replisome. |
Falkenberg M, Lehman IR, Elias P |
2000 |
| Synthesis and biological evaluation of fluorinated deoxynucleotide analogs based on bis-(difluoromethylene)triphosphoric acid. |
Surya Prakash GK, Zibinsky M, Upton TG, Kashemirov BA, McKenna CE, Oertell K, Goodman MF, Batra VK, Pedersen LC, Beard WA, Shock DD, Wilson SH, Olah GA |
2010 |
| A model for DNA polymerase switching involving a single cleft and the rim of the sliding clamp. |
Heltzel JM, Maul RW, Scouten Ponticelli SK, Sutton MD |
2009 |
| DNA polymerase epsilon and delta proofreading suppress discrete mutator and cancer phenotypes in mice. |
Albertson TM, Ogawa M, Bugni JM, Hays LE, Chen Y, Wang Y, Treuting PM, Heddle JA, Goldsby RE, Preston BD |
2009 |
| A conditional lethal mutant of Escherichia coli K12 defective in the 5' leads to 3' exonuclease associated with DNA polymerase I. |
Konrad EB, Lehman IR |
1974 |
| Translational frameshifting generates the gamma subunit of DNA polymerase III holoenzyme. |
Tsuchihashi Z, Kornberg A |
1990 |
| HIV-1 reverse transcriptase connection subdomain mutations reduce template RNA degradation and enhance AZT excision. |
Delviks-Frankenberry KA, Nikolenko GN, Boyer PL, Hughes SH, Coffin JM, Jere A, Pathak VK |
2008 |
| Synthesis by the DNA primase of Drosophila melanogaster of a primer with a unique chain length. |
Conaway RC, Lehman IR |
1982 |
| Computer simulations of protein functions: searching for the molecular origin of the replication fidelity of DNA polymerases. |
Florián J, Goodman MF, Warshel A |
2005 |
| Hybrid Ty1/HIV-1 elements used to detect inhibitors and monitor the activity of HIV-1 reverse transcriptase. |
Nissley DV, Boyer PL, Garfinkel DJ, Hughes SH, Strathern JN |
1998 |
| Crystals of a ternary complex of human immunodeficiency virus type 1 reverse transcriptase with a monoclonal antibody Fab fragment and double-stranded DNA diffract x-rays to 3.5-A resolution. |
Jacobo-Molina A, Clark AD, Williams RL, Nanni RG, Clark PK, Ferris AL, Hughes SH, Arnold E |
1991 |
| Regulation of oxidative DNA damage repair by DNA polymerase λ and MutYH by cross-talk of phosphorylation and ubiquitination. |
Markkanen E, van Loon B, Ferrari E, Parsons JL, Dianov GL, Hübscher U |
2011 |
| Error-free replicative bypass of thymine glycol by the combined action of DNA polymerases kappa and zeta in human cells. |
Yoon JH, Bhatia G, Prakash S, Prakash L |
2010 |
| Uracil incorporation: a source of pulse-labeled DNA fragments in the replication of the Escherichia coli chromosome. |
Tye BK, Chien J, Lehman IR, Duncan BK, Warner HR |
1978 |
| A DNA binding protein specific for an origin of replication of herpes simplex virus type 1. |
Elias P, O'Donnell ME, Mocarski ES, Lehman IR |
1986 |
| Yeast RPO41 gene product is required for transcription and maintenance of the mitochondrial genome. |
Greenleaf AL, Kelly JL, Lehman IR |
1986 |
| A constant rate of spontaneous mutation in DNA-based microbes. |
Drake JW |
1991 |
| Human DNA polymerase kappa forms nonproductive complexes with matched primer termini but not with mismatched primer termini. |
Carlson KD, Johnson RE, Prakash L, Prakash S, Washington MT |
2006 |
| DNA polymerase 3 star requires ATP to start synthesis on a primed DNA. |
Wickner W, Kornberg A |
1973 |
| Human immunodeficiency virus type 1 mutants resistant to nonnucleoside inhibitors of reverse transcriptase arise in tissue culture. |
Richman D, Shih CK, Lowy I, Rose J, Prodanovich P, Goff S, Griffin J |
1991 |
| Binary complex crystal structure of DNA polymerase β reveals multiple conformations of the templating 8-oxoguanine lesion. |
Batra VK, Shock DD, Beard WA, McKenna CE, Wilson SH |
2011 |
| A new form of DNA polymerase 3 and a copolymerase replicate a long, single-stranded primer-template. |
Wickner W, Schekman R, Geider K, Kornberg A |
1973 |
| The dnaN gene codes for the beta subunit of DNA polymerase III holoenzyme of escherichia coli. |
Burgers PM, Kornberg A, Sakakibara Y |
1981 |
| The delta subunit of Escherichia coli DNA polymerase III holoenzyme is the dnaX gene product. |
Hübscher U, Kornberg A |
1979 |
| Binding of RNA template to a complex of HIV-1 reverse transcriptase/primer/template. |
Canard B, Sarfati R, Richardson CC |
1997 |
| Mutations in the connection domain of HIV-1 reverse transcriptase increase 3'-azido-3'-deoxythymidine resistance. |
Nikolenko GN, Delviks-Frankenberry KA, Palmer S, Maldarelli F, Fivash MJ, Coffin JM, Pathak VK |
2007 |
| Helicase-DNA polymerase interaction is critical to initiate leading-strand DNA synthesis. |
Zhang H, Lee SJ, Zhu B, Tran NQ, Tabor S, Richardson CC |
2011 |
| Efficient translesion replication in the absence of Escherichia coli Umu proteins and 3'-5' exonuclease proofreading function. |
Vandewiele D, Borden A, O'Grady PI, Woodgate R, Lawrence CW |
1998 |
| Ubiquitylation of yeast proliferating cell nuclear antigen and its implications for translesion DNA synthesis. |
Haracska L, Unk I, Prakash L, Prakash S |
2006 |
| Isolation and characterization of a dideoxyguanosine triphosphate-resistant mutant of human immunodeficiency virus reverse transcriptase. |
Prasad VR, Lowy I, de los Santos T, Chiang L, Goff SP |
1991 |
| Reconstitution of repair-gap UV mutagenesis with purified proteins from Escherichia coli: a role for DNA polymerases III and II. |
Tomer G, Cohen-Fix O, O'Donnell ME, Goodman M, Livneh Z |
1996 |
| Human immunodeficiency virus type 1 (HIV-1) strains selected for resistance against the HIV-1-specific [2',5'-bis-O-(tert-butyldimethylsilyl)-3'-spiro- 5''-(4''-amino-1'',2''-oxathiole-2'',2''-dioxide)]-beta-D-pentofurano syl (TSAO) nucleoside analogues retain sensitivity to HIV-1-specific nonnucleoside inhibitors. |
Balzarini J, Karlsson A, Vandamme AM, Pérez-Pérez MJ, Zhang H, Vrang L, Oberg B, Bäckbro K, Unge T, San-Félix A |
1993 |
| Human immunodeficiency virus 1 (HIV-1)-specific reverse transcriptase (RT) inhibitors may suppress the replication of specific drug-resistant (E138K)RT HIV-1 mutants or select for highly resistant (Y181C-->C181I)RT HIV-1 mutants. |
Balzarini J, Karlsson A, Sardana VV, Emini EA, Camarasa MJ, De Clercq E |
1994 |
| A mutation in reverse transcriptase of bis(heteroaryl)piperazine-resistant human immunodeficiency virus type 1 that confers increased sensitivity to other nonnucleoside inhibitors. |
Dueweke TJ, Pushkarskaya T, Poppe SM, Swaney SM, Zhao JQ, Chen IS, Stevenson M, Tarpley WG |
1993 |
| Identification of amino acids in herpes simplex virus DNA polymerase involved in substrate and drug recognition. |
Gibbs JS, Chiou HC, Bastow KF, Cheng YC, Coen DM |
1988 |
| Rapid in vitro selection of human immunodeficiency virus type 1 resistant to 3'-thiacytidine inhibitors due to a mutation in the YMDD region of reverse transcriptase. |
Tisdale M, Kemp SD, Parry NR, Larder BA |
1993 |
| Fifth mutation in human immunodeficiency virus type 1 reverse transcriptase contributes to the development of high-level resistance to zidovudine. |
Kellam P, Boucher CA, Larder BA |
1992 |
| Suppression of the breakthrough of human immunodeficiency virus type 1 (HIV-1) in cell culture by thiocarboxanilide derivatives when used individually or in combination with other HIV-1-specific inhibitors (i.e., TSAO derivatives). |
Balzarini J, Pérez-Pérez MJ, Vélazquez S, San-Félix A, Camarasa MJ, De Clercq E, Karlsson A |
1995 |
| Selective pressure of a quinoxaline nonnucleoside inhibitor of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT) on HIV-1 replication results in the emergence of nucleoside RT-inhibitor-specific (RT Leu-74-->Val or Ile and Val-75-->Leu or Ile) HIV-1 mutants. |
Kleim JP, Rösner M, Winkler I, Paessens A, Kirsch R, Hsiou Y, Arnold E, Riess G |
1996 |
| DNA polymerase theta up-regulation is associated with poor survival in breast cancer, perturbs DNA replication, and promotes genetic instability. |
Lemée F, Bergoglio V, Fernandez-Vidal A, Machado-Silva A, Pillaire MJ, Bieth A, Gentil C, Baker L, Martin AL, Leduc C, Lam E, Magdeleine E, Filleron T, Oumouhou N, Kaina B, Seki M, Grimal F, Lacroix-Triki M, Thompson A, Roché H, Bourdon JC, Wood RD, Hoffmann JS, Cazaux C |
2010 |
| Replication of adenovirus DNA-protein complex with purified proteins. |
Ikeda JE, Enomoto T, Hurwitz J |
1981 |
| The alternative Ctf18-Dcc1-Ctf8-replication factor C complex required for sister chromatid cohesion loads proliferating cell nuclear antigen onto DNA. |
Bermudez VP, Maniwa Y, Tappin I, Ozato K, Yokomori K, Hurwitz J |
2003 |
| Reconstitution of human replication factor C from its five subunits in baculovirus-infected insect cells. |
Cai J, Uhlmann F, Gibbs E, Flores-Rozas H, Lee CG, Phillips B, Finkelstein J, Yao N, O'Donnell ME, Hurwitz J |
1996 |
| Association of phiX174 DNA-dependent ATPase activity with an Escherichia coli protein, replication factor Y, required for in vitro synthesis of phiX174 DNA. |
Wickner S, Hurwitz J |
1975 |
| Studies of the cloned 37-kDa subunit of activator 1 (replication factor C) of HeLa cells. |
Chen M, Pan ZQ, Hurwitz J |
1992 |
| Studies on the DNA elongation inhibitor and its proliferating cell nuclear antigen-dependent control in simian virus 40 DNA replication in vitro. |
Lee SH, Kwong AD, Ishimi Y, Hurwitz J |
1989 |
| Role of DNA polymerase alpha and DNA primase in simian virus 40 DNA replication in vitro. |
Murakami Y, Wobbe CR, Weissbach L, Dean FB, Hurwitz J |
1986 |
| DNA sequences required for the in vitro replication of adenovirus DNA. |
Guggenheimer RA, Stillman BW, Nagata K, Tamanoi F, Hurwitz J |
1984 |
| Disclosing the in vivo organization of a viral histone-like protein in Bacillus subtilis mediated by its capacity to recognize the viral genome. |
Holguera I, Ballesteros-Plaza D, Muñoz-Espín D, Salas M |
2012 |
| Properties of the human Cdc45/Mcm2-7/GINS helicase complex and its action with DNA polymerase {varepsilon} in rolling circle DNA synthesis. |
Kang YH, Galal WC, Farina A, Tappin I, Hurwitz J |
2012 |
| Y265C DNA polymerase beta knockin mice survive past birth and accumulate base excision repair intermediate substrates. |
Senejani AG, Dalal S, Liu Y, Nottoli TP, McGrath JM, Clairmont CS, Sweasy JB |
2012 |
| Structural basis of human DNA polymerase η-mediated chemoresistance to cisplatin. |
Zhao Y, Biertümpfel C, Gregory MT, Hua YJ, Hanaoka F, Yang WW |
2012 |
| Genomic footprinting in mammalian cells with ultraviolet light. |
Becker MM, Wang Z, Grossmann G, Becherer KA |
1989 |
| On the molecular basis of transition mutations: frequencies of forming 2-aminopurine.cytosine and adenine.cytosine base mispairs in vitro. |
Watanabe SM, Goodman MF |
1981 |
| Replication of simian virus 40 origin-containing DNA in vitro with purified proteins. |
Wobbe CR, Weissbach L, Borowiec JA, Dean FB, Murakami Y, Bullock P, Hurwitz J |
1987 |
| Mechanism of action of ribonuclease H isolated from avian myeloblastosis virus and Escherichia coli. |
Leis JP, Berkower I, Hurwitz J |
1973 |
| In situ analysis of repair processes for oxidative DNA damage in mammalian cells. |
Lan L, Nakajima S, Oohata Y, Takao M, Okano S, Masutani M, Wilson SH, Yasui A |
2004 |
| Different mutation signatures in DNA polymerase eta- and MSH6-deficient mice suggest separate roles in antibody diversification. |
Martomo SA, Yang WW, Wersto RP, Ohkumo T, Kondo Y, Yokoi M, Masutani C, Hanaoka F, Gearhart PJ |
2005 |
| Structure of the gene 2.5 protein, a single-stranded DNA binding protein encoded by bacteriophage T7. |
Hollis T, Stattel JM, Walther DS, Richardson CC, Ellenberger T |
2001 |
| An N-terminal fragment of the gene 4 helicase/primase of bacteriophage T7 retains primase activity in the absence of helicase activity. |
Frick DN, Baradaran K, Richardson CC |
1998 |
| A general two-metal-ion mechanism for catalytic RNA. |
Steitz TA, Steitz JA |
1993 |
| Viral terminal protein directs early organization of phage DNA replication at the bacterial nucleoid. |
Muñoz-Espín D, Holguera I, Ballesteros-Plaza D, Carballido-López R, Salas M |
2010 |
| Direct role for the RNA polymerase domain of T7 primase in primer delivery. |
Zhu B, Lee SJ, Richardson CC |
2010 |
| Residues in the central beta-hairpin of the DNA helicase of bacteriophage T7 are important in DNA unwinding. |
Satapathy AK, Kochaniak AB, Mukherjee S, Crampton DJ, van Oijen AM, Richardson CC |
2010 |
| Human DINB1-encoded DNA polymerase kappa is a promiscuous extender of mispaired primer termini. |
Washington MT, Johnson RE, Prakash L, Prakash S |
2002 |
| Genome-wide model for the normal eukaryotic DNA replication fork. |
Larrea AA, Lujan SA, Nick McElhinny SA, Mieczkowski PA, Resnick MA, Gordenin DA, Kunkel TA |
2010 |
| Frameshift errors initiated by nucleotide misincorporation. |
Bebenek K, Kunkel TA |
1990 |
| Infidelity of DNA synthesis associated with bypass of apurinic sites. |
Schaaper RM, Kunkel TA, Loeb LA |
1983 |
| Intrinsic apurinic/apyrimidinic (AP) endonuclease activity enables Bacillus subtilis DNA polymerase X to recognize, incise, and further repair abasic sites. |
Baños B, Villar L, Salas M, de Vega M |
2010 |
| Phage phi29 protein p56 prevents viral DNA replication impairment caused by uracil excision activity of uracil-DNA glycosylase. |
Serrano-Heras G, Bravo A, Salas M |
2008 |
| The vinyl chloride DNA derivative N2,3-ethenoguanine produces G----A transitions in Escherichia coli. |
Cheng KC, Preston BD, Cahill DS, Dosanjh MK, Singer B, Loeb LA |
1991 |
| Mutagenic potential of O4-methylthymine in vivo determined by an enzymatic approach to site-specific mutagenesis. |
Preston BD, Singer B, Loeb LA |
1986 |
| Depurination causes mutations in SOS-induced cells. |
Schaaper RM, Loeb LA |
1981 |
| Metal-induced infidelity during DNA synthesis. |
Sirover MA, Loeb LA |
1976 |
| Reverse transcriptase: correlation of zinc content with activity. |
Poiesz BJ, Seal G, Loeb LA |
1974 |
| Priming of DNA polymerase in nuclei of sea urchin embryos by native DNA. |
Loeb LA, Mazia D, Ruby AD |
1967 |
| Translesion DNA polymerases remodel the replisome and alter the speed of the replicative helicase. |
Indiani C, Langston LD, Yurieva O, Goodman MF, O'Donnell ME |
2009 |
| Roles of DNA polymerases V and II in SOS-induced error-prone and error-free repair in Escherichia coli. |
Pham P, Rangarajan S, Woodgate R, Goodman MF |
2001 |
| A fidelity assay using "dideoxy" DNA sequencing: a measurement of sequence dependence and frequency of forming 5-bromouracil X guanine base mispairs. |
Lasken RS, Goodman MF |
1985 |
| Evidence for an altered adenovirus DNA polymerase in cells infected with the mutant H5ts149. |
Friefeld BR, Lichy JH, Hurwitz J, Horwitz MS |
1983 |
| Hopping of a processivity factor on DNA revealed by single-molecule assays of diffusion. |
Komazin-Meredith G, Mirchev R, Golan DE, van Oijen AM, Coen DM |
2008 |
| Sequence and mapping analyses of the herpes simplex virus DNA polymerase gene predict a C-terminal substrate binding domain. |
Gibbs JS, Chiou HC, Hall JD, Mount DW, Retondo MJ, Weller SK, Coen DM |
1985 |
| Adenovirus DNA replication in vitro: identification of a host factor that stimulates synthesis of the preterminal protein-dCMP complex. |
Nagata K, Guggenheimer RA, Enomoto T, Lichy JH, Hurwitz J |
1982 |
| Adenovirus DNA replication in vitro: purification of the terminal protein in a functional form. |
Enomoto T, Lichy JH, Ikeda JE, Hurwitz J |
1981 |
| Elongation of primed DNA templates by eukaryotic DNA polymerases. |
Ikeda JE, Longiaru M, Horwitz MS, Hurwitz J |
1980 |
| The accessory subunit of mtDNA polymerase shares structural homology with aminoacyl-tRNA synthetases: implications for a dual role as a primer recognition factor and processivity clamp. |
Fan L, Sanschagrin PC, Kaguni LS, Kuhn LA |
1999 |
| Crystal structure of the GINS complex and functional insights into its role in DNA replication. |
Chang YP, Wang G, Bermudez V, Hurwitz J, Chen XS |
2007 |
| Studies on the interactions between human replication factor C and human proliferating cell nuclear antigen. |
Zhang G, Gibbs E, Kelman Z, O'Donnell ME, Hurwitz J |
1999 |
| Sequence and expression in Escherichia coli of the 40-kDa subunit of activator 1 (replication factor C) of HeLa cells. |
Chen M, Pan ZQ, Hurwitz J |
1992 |
| Molecular interactions in the priming complex of bacteriophage T7. |
Kulczyk AW, Richardson CC |
2012 |
| Involvement of escherichia coli dnaZ gene product in DNA elongation in vitro. |
Wickner S, Hurwitz J |
1976 |
| Initiation of replication in chromosomal DNA induced by extracts from proliferating cells. |
Jazwinski SM, Wang JL, Edelman GM |
1976 |
| Chromosomal location of the human gene for DNA polymerase beta. |
McBride OW, Zmudzka BZ, Wilson SH |
1987 |
| Structure of rat DNA polymerase beta revealed by partial amino acid sequencing and cDNA cloning. |
Zmudzka BZ, SenGupta D, Matsukage A, Cobianchi F, Kumar P, Wilson SH |
1986 |
| A human homolog of the Saccharomyces cerevisiae REV3 gene, which encodes the catalytic subunit of DNA polymerase zeta. |
Gibbs PE, McGregor WG, Maher VM, Nisson P, Lawrence CW |
1998 |
| Oncornavirus expression in human x mouse hybrid cells segregating mouse chromosomes. |
Minna JD, Gazdar AF, Iverson GM, Marshall TH, STORMBERG K, Wilson SH |
1974 |
| Mutator phenotypes of yeast strains heterozygous for mutations in the MSH2 gene. |
Drotschmann K, Clark AB, Tran HT, Resnick MA, Gordenin DA, Kunkel TA |
1999 |
| Unequal human immunodeficiency virus type 1 reverse transcriptase error rates with RNA and DNA templates. |
Boyer JC, Bebenek K, Kunkel TA |
1992 |
| Lethal mutagenesis of HIV with mutagenic nucleoside analogs. |
Loeb LA, Essigmann JM, Kazazi F, Zhang J, Rose KD, Mullins JI |
1999 |
| Posttranscriptional modification of retroviral primers is required for late stages of DNA replication. |
Burnett BP, McHenry CS |
1997 |
| Reverse transcriptase of human immunodeficiency virus can use either human tRNA(3Lys) or Escherichia coli tRNA(2Gln) as a primer in an in vitro primer-utilization assay. |
Kohlstaedt LA, Steitz TA |
1992 |
| Gene 1.7 of bacteriophage T7 confers sensitivity of phage growth to dideoxythymidine. |
Tran NQ, Rezende LF, Qimron U, Richardson CC, Tabor S |
2008 |
| Initiation of DNA replication at the primary origin of bacteriophage T7 by purified proteins: requirement for T7 RNA polymerase. |
Romano LJ, Tamanoi F, Richardson CC |
1981 |
| The gamma subunit of DNA polymerase III holoenzyme of Escherichia coli is produced by ribosomal frameshifting. |
Flower AM, McHenry CS |
1990 |
| UmuC mutagenesis protein of Escherichia coli: purification and interaction with UmuD and UmuD'. |
Woodgate R, Rajagopalan M, Lu C, Echols H |
1989 |
| Conversion of phiX174 and fd single-stranded DNA to replicative forms in extracts of Escherichia coli. |
Wickner RB, Wright M, Wickner S, Hurwitz J |
1972 |
| Two distinct loci confer resistance to acycloguanosine in herpes simplex virus type 1. |
Coen DM, Schaffer PA |
1980 |
| Conversion of phiX174 viral DNA to double-stranded form by purified Escherichia coli proteins. |
Wickner S, Hurwitz J |
1974 |
| Studies on the initiation of simian virus 40 replication in vitro: RNA primer synthesis and its elongation. |
Murakami Y, Eki T, Hurwitz J |
1992 |
| Studies on the initiation and elongation reactions in the simian virus 40 DNA replication system. |
Matsumoto T, Eki T, Hurwitz J |
1990 |
| Involvement of two protein factors and ATP in in vitro DNA synthesis catalyzed by DNA polymerase 3 of Escherichia coli. |
Hurwitz J, Wickner S |
1974 |
| ATP hydrolysis catalyzed by human replication factor C requires participation of multiple subunits. |
Cai J, Yao N, Gibbs E, Finkelstein J, Phillips B, O'Donnell ME, Hurwitz J |
1998 |
| In vitro reconstitution of human replication factor C from its five subunits. |
Uhlmann F, Cai J, Flores-Rozas H, Dean FB, Finkelstein J, O'Donnell ME, Hurwitz J |
1996 |
| The subunits of activator 1 (replication factor C) carry out multiple functions essential for proliferating-cell nuclear antigen-dependent DNA synthesis. |
Pan ZQ, Chen M, Hurwitz J |
1993 |
| Species-specific in vitro synthesis of DNA containing the polyoma virus origin of replication. |
Murakami Y, Eki T, Yamada M, Prives C, Hurwitz J |
1986 |
| Adenovirus DNA replication in vitro: synthesis of full-length DNA with purified proteins. |
Nagata K, Guggenheimer RA, Hurwitz J |
1983 |
| Adenoviral protein-primed initiation of DNA chains in vitro. |
Ikeda JE, Enomoto T, Hurwitz J |
1982 |
| Mechanism of ultraviolet-induced mutagenesis: extent and fidelity of in vitro DNA synthesis on irradiated templates. |
Villani G, Boiteux S, Radman M |
1978 |
| Knotted DNA from bacteriophage capsids. |
Liu LF, Perkocha L, Calendar R, Wang JC |
1981 |
| Reverse chemical mutagenesis: identification of the mutagenic lesions resulting from reactive oxygen species-mediated damage to DNA. |
Feig DI, Sowers LC, Loeb LA |
1994 |
| Structural basis of asymmetry in the human immunodeficiency virus type 1 reverse transcriptase heterodimer. |
Wang J, Smerdon SJ, Jäger J, Kohlstaedt LA, Rice PA, Friedman JM, Steitz TA |
1994 |
| Recognition by viral and cellular DNA polymerases of nucleosides bearing bases with nonstandard hydrogen bonding patterns. |
Horlacher J, Hottiger M, Podust VN, Hübscher U, Benner SA |
1995 |
| Active DNA unwinding dynamics during processive DNA replication. |
Morin JA, Cao FJ, Lázaro JM, Arias-Gonzalez JR, Valpuesta JM, Carrascosa JL, Salas M, Ibarra B |
2012 |
| The p15 carboxyl-terminal proteolysis product of the human immunodeficiency virus type 1 reverse transcriptase p66 has DNA polymerase activity. |
Hafkemeyer P, Ferrari E, Brecher J, Hübscher U |
1991 |
| The joining (J) chain is present in invertebrates that do not express immunoglobulins. |
Takahashi T, Iwase T, Takenouchi N, Saito M, Kobayashi K, Moldoveanu Z, Mestecky J, Moro I |
1996 |
| Suppressed catalytic activity of base excision repair enzymes on rotationally positioned uracil in nucleosomes. |
Beard BC, Wilson SH, Smerdon MJ |
2003 |
| A short adaptive path from DNA to RNA polymerases. |
Cozens C, Pinheiro VB, Vaisman A, Woodgate R, Holliger P |
2012 |
| Gene 5.5 protein of bacteriophage T7 in complex with Escherichia coli nucleoid protein H-NS and transfer RNA masks transfer RNA priming in T7 DNA replication. |
Zhu B, Lee SJ, Tan M, Wang ED, Richardson CC |
2012 |
| Pol31 and Pol32 subunits of yeast DNA polymerase δ are also essential subunits of DNA polymerase ζ |
Johnson RE, Prakash L, Prakash S |
2012 |
| 2',5'-Bis-O-(tert-butyldimethylsilyl)-3'-spiro-5''-(4''-amino-1'',2''- oxathiole-2'',2'-dioxide)pyrimidine (TSAO) nucleoside analogues: highlyselective inhibitors of human immunodeficiency virus type 1 that are targeted at the viral reverse transcriptase. |
Balzarini J, Pérez-Pérez MJ, San-Félix A, Schols D, Perno CF, Vandamme AM, Camarasa MJ, De Clercq E |
1992 |
| Mechanism of inhibitory effect of dextran sulfate and heparin on replication of human immunodeficiency virus in vitro. |
Baba M, Pauwels R, Balzarini J, Arnout J, Desmyter J, De Clercq E |
1988 |
| Inhibition of oncornavirus functions by 2'-azido polynucleotides. |
De Clercq E, Billiau A, Hobbs J, Torrence PF, Witkop B |
1975 |
| Importance of compartment formation for a self-encoding system. |
Matsuura T, Yamaguchi M, Ko-Mitamura EP, Shima Y, Urabe I, Yomo T |
2002 |
| 9-[(2RS)-3-fluoro-2-phosphonylmethoxypropyl] derivatives of purines: a class of highly selective antiretroviral agents in vitro and in vivo. |
Balzarini J, Holy A, Jindrich J, Dvorakova H, Hao Z, Snoeck R, Herdewijn P, Johns DG, De Clercq E |
1991 |
| Mutated K65R recombinant reverse transcriptase of human immunodeficiency virus type 1 shows diminished chain termination in the presence of 2',3'-dideoxycytidine 5'-triphosphate and other drugs. |
Gu Z, Arts EJ, Parniak MA, Wainberg MA |
1995 |
| On the mechanism of selective inhibition of herpesvirus replication by (E)-5-(2-bromovinyl)-2'-deoxyuridine. |
Allaudeen HS, Kozarich JW, Bertino JR, De Clercq E |
1981 |
| Potent and selective inhibition of human immunodeficiency virus type 1 (HIV-1) by 5-ethyl-6-phenylthiouracil derivatives through their interaction with the HIV-1 reverse transcriptase. |
Baba M, De Clercq E, Tanaka H, Ubasawa M, Takashima H, Sekiya K, Nitta I, Umezu K, Nakashima H, Mori S |
1991 |
| Mechanism of somatic hypermutation at the WA motif by human DNA polymerase η |
Zhao Y, Gregory MT, Biertümpfel C, Hua YJ, Hanaoka F, Yang WW |
2013 |
| Dual role for mammalian DNA polymerase ζ in maintaining genome stability and proliferative responses. |
Lange SS, Bedford E, Reh S, Wittschieben JP, Carbajal S, Kusewitt DF, DiGiovanni J, Wood RD |
2013 |
| RecA acts as a switch to regulate polymerase occupancy in a moving replication fork. |
Indiani C, Patel M, Goodman MF, O'Donnell ME |
2013 |
| Evidence for allosterism in in vitro DNA synthesis on RNA templates. |
Cavalieri LF, Modak MJ, Marcus SL |
1974 |
| Structure-function analysis of ribonucleotide bypass by B family DNA replicases. |
Clausen AR, Murray MS, Passer AR, Pedersen LC, Kunkel TA |
2013 |
| DNA polymerase δ-interacting protein 2 is a processivity factor for DNA polymerase λ during 8-oxo-7,8-dihydroguanine bypass. |
Maga G, Crespan E, Markkanen E, Imhof R, Furrer A, Villani G, Hübscher U, van Loon B |
2013 |
| ENZYMATIC SYNTHESIS OF DEOXYRIBONUCLEIC ACID, XVI. OLIGONUCLEOTIDES AS TEMPLATES AND THE MECHANISM OF THEIR REPLICATION. |
Kornberg A, BERTSCH LL, JACKSON JF, KHORANA HG |
1964 |