Proceedings of the National Academy of Sciences of the United States of America

(Proc Natl Acad Sci U S A) ISSNs: , 1091-6490

References in Proceedings of the National Academy of Sciences of the United States of America:

Title Authors Year
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Unique features in the structure of the complex between HIV-1 reverse transcriptase and the bis(heteroaryl)piperazine (BHAP) U-90152 explain resistance mutations for this nonnucleoside inhibitor. Esnouf RM, Ren J, Hopkins AL, Ross CK, Jones EY, Stammers DK, Stuart DI 1997
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Thermostable DNA polymerase chain amplification of t(14;18) chromosome breakpoints and detection of minimal residual disease. Crescenzi M, Seto M, Herzig GP, Weiss PD, Griffith RC, Korsmeyer SJ 1988
The influence of neighboring base pairs upon base-pair substitution mutation rates. Koch RE 1971
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Overexpression of DNA polymerase beta in cell results in a mutator phenotype and a decreased sensitivity to anticancer drugs. Canitrot Y, Cazaux C, Fréchet M, Bouayadi K, Lesca C, Salles B, Hoffmann JS 1998
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A beta-like DNA polymerase activity in the slime mold Dictyostelium discoideum. Baril EF, Scheiner C, Pederson T 1980
Functional interaction between the Werner Syndrome protein and DNA polymerase delta. Kamath-Loeb AS, Johansson E, Burgers PM, Loeb LA 2000
A structural gap in Dpo4 supports mutagenic bypass of a major benzo[a]pyrene dG adduct in DNA through template misalignment. Bauer J, Xing G, Yagi H, Sayer JM, Jerina DM, Ling H 2007
A single mutation in poliovirus RNA-dependent RNA polymerase confers resistance to mutagenic nucleotide analogs via increased fidelity. Pfeiffer JK, Kirkegaard K 2003
Mice reconstituted with DNA polymerase beta-deficient fetal liver cells are able to mount a T cell-dependent immune response and mutate their Ig genes normally. Esposito G, Texido G, Betz UA, Gu H, Müller W, Klein U, Rajewsky K 2000
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The Escherichia coli SOS mutagenesis proteins UmuD and UmuD' interact physically with the replicative DNA polymerase. Sutton MD, Opperman T, Walker GC 1999
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DNA polymerase delta isolated from Schizosaccharomyces pombe contains five subunits. Zuo S, Gibbs E, Kelman Z, Wang TS, O'Donnell ME, MacNeill SA, Hurwitz J 1997
Polkappa protects mammalian cells against the lethal and mutagenic effects of benzo[a]pyrene. Ogi T, Shinkai Y, Tanaka K, Ohmori H 2002
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A single residue in DNA polymerases of the Escherichia coli DNA polymerase I family is critical for distinguishing between deoxy- and dideoxyribonucleotides. Tabor S, Richardson CC 1995
Incorrect nucleotide insertion at the active site of a G:A mismatch catalyzed by DNA polymerase beta. Lin P, Batra VK, Pedersen LC, Beard WA, Wilson SH, Pedersen LG 2008
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PCNA binding domains in all three subunits of yeast DNA polymerase {delta} modulate its function in DNA replication. Acharya N, Klassen R, Johnson RE, Prakash L, Prakash S 2011
Crystal structure of human immunodeficiency virus type 1 reverse transcriptase complexed with double-stranded DNA at 3.0 A resolution shows bent DNA. Jacobo-Molina A, Ding J, Nanni RG, Clark AD, Lu X, Tantillo C, Williams RL, Kamer G, Ferris AL, Clark PK 1993
Kinetic measurement of 2-aminopurine X cytosine and 2-aminopurine X thymine base pairs as a test of DNA polymerase fidelity mechanisms. Watanabe SM, Goodman MF 1982
Correlations between the activities of DNA polymerase alpha and the glucocorticoid receptor. Schmidt TJ, Bollum FJ, Litwack G 1982
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Demonstration of a stimulatory protein for virus-specified DNA polymerase in phorbol ester-treated Epstein-Barr virus-carrying cells. Chiou JF, Li JK, Cheng YC 1985
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Cocrystal structure of an editing complex of Klenow fragment with DNA. Freemont PS, Friedman JM, Beese LS, Sanderson MR, Steitz TA 1988
DNA conformational changes at the primer-template junction regulate the fidelity of replication by DNA polymerase. Datta K, Johnson NP, von Hippel PH 2010
Identification of a higher molecular weight DNA polymerase alpha catalytic polypeptide in monkey cells by monoclonal antibody. Karawya E, Swack J, Albert W, Fedorko J, Minna JD, Wilson SH 1984
A cancer-associated DNA polymerase delta variant modeled in yeast causes a catastrophic increase in genomic instability. Daee DL, Mertz TM, Shcherbakova PV 2010
Archaeal eukaryote-like Orc1/Cdc6 initiators physically interact with DNA polymerase B1 and regulate its functions. Zhang L, Zhang L, Liu Y, Yang S, Gao C, Gong H, Feng Y, He ZG 2009
Efficient and accurate bypass of N2-(1-carboxyethyl)-2'-deoxyguanosine by DinB DNA polymerase in vitro and in vivo. Yuan B, Cao H, Jiang Y, Hong H, Wang Y 2008
Conformational transitions in DNA polymerase I revealed by single-molecule FRET. Santoso Y, Joyce CM, Potapova O, Le Reste L, Hohlbein J, Torella JP, Grindley ND, Kapanidis AN 2010
A heterodimeric DNA polymerase: evidence that members of Euryarchaeota possess a distinct DNA polymerase. Cann IK, Komori K, Toh H, Kanai S, Ishino Y 1998
Enzymatic joining of DNA strands: a novel reaction of diphosphopyridine nucleotide. Zimmerman SB, Little JW, Oshinsky CK, Gellert M 1967
Separation of the adenovirus terminal protein precursor from its associated DNA polymerase: role of both proteins in the initiation of adenovirus DNA replication. Lichy JH, Field J, Horwitz MS, Hurwitz J 1982
A type IB topoisomerase with DNA repair activities. Belova GI, Prasad R, Kozyavkin SA, Lake JA, Wilson SH, Slesarev AI 2001
Comparative properties of RNA and DNA templates for the DNA polymerase of Rous sarcoma virus. Duesberg P, Helm KV, Canaani E 1971
DNA polymerase alpha mutants from a Drosophila melanogaster cell line. Sugino A, Nakayama K 1980
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DNA endonucleases associated with the avian myeloblastosis virus DNA polymerase. Samuel KP, Papas TS, Chirikjian JG 1979
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Replication of duplex DNA by bacteriophage T7 DNA polymerase and gene 4 protein is accompanied by hydrolysis of nucleoside 5'-triphosphates. Kolodner R, Richardson CC 1977
Mechanism of DNA polymerase II-mediated frameshift mutagenesis. Becherel OJ, Fuchs RP 2001
Genetic analysis of the interaction between bacteriophage T7 DNA polymerase and Escherichia coli thioredoxin. Himawan JS, Richardson CC 1992
Targeting of DNA polymerase to the adenovirus origin of DNA replication by interaction with nuclear factor I. Armentero MT, Horwitz M, Mermod N 1994
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DPB2, the gene encoding DNA polymerase II subunit B, is required for chromosome replication in Saccharomyces cerevisiae. Araki H, Hamatake RK, Johnston LH, Sugino A 1991
3'-Azido-3'-deoxythymidine drug resistance mutations in HIV-1 reverse transcriptase can induce long range conformational changes. Ren J, Esnouf RM, Hopkins AL, Jones EY, Kirby I, Keeling J, Ross CK, Larder BA, Stuart DI, Stammers DK 1998
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Single-strand binding protein enhances fidelity of DNA synthesis in vitro. Kunkel TA, Meyer RR, Loeb LA 1979
A tumor necrosis factor alpha- and interleukin 6-inducible protein that interacts with the small subunit of DNA polymerase delta and proliferating cell nuclear antigen. He H, Tan CK, Downey KM, So AG 2001
Identification of a transient excision intermediate at the crossroads between DNA polymerase extension and proofreading pathways. Baker RP, Reha-Krantz LJ 1998
Protein affinity chromatography with purified yeast DNA polymerase alpha detects proteins that bind to DNA polymerase. Miles J, Formosa T 1992
Mismatch-specific 3'----5' exonuclease associated with the mitochondrial DNA polymerase from Drosophila embryos. Kaguni LS, Olson MW 1989
Hydrogen bonding revisited: geometric selection as a principal determinant of DNA replication fidelity. Goodman MF 1997
Rapid assembly of the bacteriophage T4 core replication complex on a linear primer/template construct. Kaboord BF, Benkovic SJ 1993
Interaction of the beta sliding clamp with MutS, ligase, and DNA polymerase I. López de Saro FJ, O'Donnell ME 2001
Analysis of mutations at positions 115 and 116 in the dNTP binding site of HIV-1 reverse transcriptase. Boyer PL, Sarafianos SG, Arnold E, Hughes SH 2000
Activity of the purified mutagenesis proteins UmuC, UmuD', and RecA in replicative bypass of an abasic DNA lesion by DNA polymerase III. Rajagopalan M, Lu C, Woodgate R, O'Donnell ME, Goodman MF, Echols H 1992
Pentaribonucleotides of mixed sequence are synthesized and efficiently prime de novo DNA chain starts in the T4 bacteriophage DNA replication system. Liu CC, Alberts BM 1980
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Isolation and partial characterization of a mutant of Escherichia coli deficient in DNA polymerase II. Campbell JL, Soll L, Richardson CC 1972
Expression of soluble, enzymatically active, human immunodeficiency virus reverse transcriptase in Escherichia coli and analysis of mutants. Hizi A, McGill C, Hughes SH 1988
Structural basis for the synthesis of nucleobase modified DNA by Thermus aquaticus DNA polymerase. Obeid S, Baccaro A, Welte W, Diederichs K, Marx A 2010
Leading and lagging strand DNA synthesis in vitro by a reconstituted herpes simplex virus type 1 replisome. Falkenberg M, Lehman IR, Elias P 2000
Synthesis and biological evaluation of fluorinated deoxynucleotide analogs based on bis-(difluoromethylene)triphosphoric acid. Surya Prakash GK, Zibinsky M, Upton TG, Kashemirov BA, McKenna CE, Oertell K, Goodman MF, Batra VK, Pedersen LC, Beard WA, Shock DD, Wilson SH, Olah GA 2010
A model for DNA polymerase switching involving a single cleft and the rim of the sliding clamp. Heltzel JM, Maul RW, Scouten Ponticelli SK, Sutton MD 2009
DNA polymerase epsilon and delta proofreading suppress discrete mutator and cancer phenotypes in mice. Albertson TM, Ogawa M, Bugni JM, Hays LE, Chen Y, Wang Y, Treuting PM, Heddle JA, Goldsby RE, Preston BD 2009
A conditional lethal mutant of Escherichia coli K12 defective in the 5' leads to 3' exonuclease associated with DNA polymerase I. Konrad EB, Lehman IR 1974
Translational frameshifting generates the gamma subunit of DNA polymerase III holoenzyme. Tsuchihashi Z, Kornberg A 1990
HIV-1 reverse transcriptase connection subdomain mutations reduce template RNA degradation and enhance AZT excision. Delviks-Frankenberry KA, Nikolenko GN, Boyer PL, Hughes SH, Coffin JM, Jere A, Pathak VK 2008
Synthesis by the DNA primase of Drosophila melanogaster of a primer with a unique chain length. Conaway RC, Lehman IR 1982
Computer simulations of protein functions: searching for the molecular origin of the replication fidelity of DNA polymerases. Florián J, Goodman MF, Warshel A 2005
Hybrid Ty1/HIV-1 elements used to detect inhibitors and monitor the activity of HIV-1 reverse transcriptase. Nissley DV, Boyer PL, Garfinkel DJ, Hughes SH, Strathern JN 1998
Crystals of a ternary complex of human immunodeficiency virus type 1 reverse transcriptase with a monoclonal antibody Fab fragment and double-stranded DNA diffract x-rays to 3.5-A resolution. Jacobo-Molina A, Clark AD, Williams RL, Nanni RG, Clark PK, Ferris AL, Hughes SH, Arnold E 1991
Regulation of oxidative DNA damage repair by DNA polymerase λ and MutYH by cross-talk of phosphorylation and ubiquitination. Markkanen E, van Loon B, Ferrari E, Parsons JL, Dianov GL, Hübscher U 2011
Error-free replicative bypass of thymine glycol by the combined action of DNA polymerases kappa and zeta in human cells. Yoon JH, Bhatia G, Prakash S, Prakash L 2010
Uracil incorporation: a source of pulse-labeled DNA fragments in the replication of the Escherichia coli chromosome. Tye BK, Chien J, Lehman IR, Duncan BK, Warner HR 1978
A DNA binding protein specific for an origin of replication of herpes simplex virus type 1. Elias P, O'Donnell ME, Mocarski ES, Lehman IR 1986
Yeast RPO41 gene product is required for transcription and maintenance of the mitochondrial genome. Greenleaf AL, Kelly JL, Lehman IR 1986
A constant rate of spontaneous mutation in DNA-based microbes. Drake JW 1991
Human DNA polymerase kappa forms nonproductive complexes with matched primer termini but not with mismatched primer termini. Carlson KD, Johnson RE, Prakash L, Prakash S, Washington MT 2006
DNA polymerase 3 star requires ATP to start synthesis on a primed DNA. Wickner W, Kornberg A 1973
Human immunodeficiency virus type 1 mutants resistant to nonnucleoside inhibitors of reverse transcriptase arise in tissue culture. Richman D, Shih CK, Lowy I, Rose J, Prodanovich P, Goff S, Griffin J 1991
Binary complex crystal structure of DNA polymerase β reveals multiple conformations of the templating 8-oxoguanine lesion. Batra VK, Shock DD, Beard WA, McKenna CE, Wilson SH 2011
A new form of DNA polymerase 3 and a copolymerase replicate a long, single-stranded primer-template. Wickner W, Schekman R, Geider K, Kornberg A 1973
The dnaN gene codes for the beta subunit of DNA polymerase III holoenzyme of escherichia coli. Burgers PM, Kornberg A, Sakakibara Y 1981
The delta subunit of Escherichia coli DNA polymerase III holoenzyme is the dnaX gene product. Hübscher U, Kornberg A 1979
Binding of RNA template to a complex of HIV-1 reverse transcriptase/primer/template. Canard B, Sarfati R, Richardson CC 1997
Mutations in the connection domain of HIV-1 reverse transcriptase increase 3'-azido-3'-deoxythymidine resistance. Nikolenko GN, Delviks-Frankenberry KA, Palmer S, Maldarelli F, Fivash MJ, Coffin JM, Pathak VK 2007
Helicase-DNA polymerase interaction is critical to initiate leading-strand DNA synthesis. Zhang H, Lee SJ, Zhu B, Tran NQ, Tabor S, Richardson CC 2011
Efficient translesion replication in the absence of Escherichia coli Umu proteins and 3'-5' exonuclease proofreading function. Vandewiele D, Borden A, O'Grady PI, Woodgate R, Lawrence CW 1998
Ubiquitylation of yeast proliferating cell nuclear antigen and its implications for translesion DNA synthesis. Haracska L, Unk I, Prakash L, Prakash S 2006
Isolation and characterization of a dideoxyguanosine triphosphate-resistant mutant of human immunodeficiency virus reverse transcriptase. Prasad VR, Lowy I, de los Santos T, Chiang L, Goff SP 1991
Reconstitution of repair-gap UV mutagenesis with purified proteins from Escherichia coli: a role for DNA polymerases III and II. Tomer G, Cohen-Fix O, O'Donnell ME, Goodman M, Livneh Z 1996
Human immunodeficiency virus type 1 (HIV-1) strains selected for resistance against the HIV-1-specific [2',5'-bis-O-(tert-butyldimethylsilyl)-3'-spiro- 5''-(4''-amino-1'',2''-oxathiole-2'',2''-dioxide)]-beta-D-pentofurano syl (TSAO) nucleoside analogues retain sensitivity to HIV-1-specific nonnucleoside inhibitors. Balzarini J, Karlsson A, Vandamme AM, Pérez-Pérez MJ, Zhang H, Vrang L, Oberg B, Bäckbro K, Unge T, San-Félix A 1993
Human immunodeficiency virus 1 (HIV-1)-specific reverse transcriptase (RT) inhibitors may suppress the replication of specific drug-resistant (E138K)RT HIV-1 mutants or select for highly resistant (Y181C-->C181I)RT HIV-1 mutants. Balzarini J, Karlsson A, Sardana VV, Emini EA, Camarasa MJ, De Clercq E 1994
A mutation in reverse transcriptase of bis(heteroaryl)piperazine-resistant human immunodeficiency virus type 1 that confers increased sensitivity to other nonnucleoside inhibitors. Dueweke TJ, Pushkarskaya T, Poppe SM, Swaney SM, Zhao JQ, Chen IS, Stevenson M, Tarpley WG 1993
Identification of amino acids in herpes simplex virus DNA polymerase involved in substrate and drug recognition. Gibbs JS, Chiou HC, Bastow KF, Cheng YC, Coen DM 1988
Rapid in vitro selection of human immunodeficiency virus type 1 resistant to 3'-thiacytidine inhibitors due to a mutation in the YMDD region of reverse transcriptase. Tisdale M, Kemp SD, Parry NR, Larder BA 1993
Fifth mutation in human immunodeficiency virus type 1 reverse transcriptase contributes to the development of high-level resistance to zidovudine. Kellam P, Boucher CA, Larder BA 1992
Suppression of the breakthrough of human immunodeficiency virus type 1 (HIV-1) in cell culture by thiocarboxanilide derivatives when used individually or in combination with other HIV-1-specific inhibitors (i.e., TSAO derivatives). Balzarini J, Pérez-Pérez MJ, Vélazquez S, San-Félix A, Camarasa MJ, De Clercq E, Karlsson A 1995
Selective pressure of a quinoxaline nonnucleoside inhibitor of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT) on HIV-1 replication results in the emergence of nucleoside RT-inhibitor-specific (RT Leu-74-->Val or Ile and Val-75-->Leu or Ile) HIV-1 mutants. Kleim JP, Rösner M, Winkler I, Paessens A, Kirsch R, Hsiou Y, Arnold E, Riess G 1996
DNA polymerase theta up-regulation is associated with poor survival in breast cancer, perturbs DNA replication, and promotes genetic instability. Lemée F, Bergoglio V, Fernandez-Vidal A, Machado-Silva A, Pillaire MJ, Bieth A, Gentil C, Baker L, Martin AL, Leduc C, Lam E, Magdeleine E, Filleron T, Oumouhou N, Kaina B, Seki M, Grimal F, Lacroix-Triki M, Thompson A, Roché H, Bourdon JC, Wood RD, Hoffmann JS, Cazaux C 2010
Replication of adenovirus DNA-protein complex with purified proteins. Ikeda JE, Enomoto T, Hurwitz J 1981
The alternative Ctf18-Dcc1-Ctf8-replication factor C complex required for sister chromatid cohesion loads proliferating cell nuclear antigen onto DNA. Bermudez VP, Maniwa Y, Tappin I, Ozato K, Yokomori K, Hurwitz J 2003
Reconstitution of human replication factor C from its five subunits in baculovirus-infected insect cells. Cai J, Uhlmann F, Gibbs E, Flores-Rozas H, Lee CG, Phillips B, Finkelstein J, Yao N, O'Donnell ME, Hurwitz J 1996
Association of phiX174 DNA-dependent ATPase activity with an Escherichia coli protein, replication factor Y, required for in vitro synthesis of phiX174 DNA. Wickner S, Hurwitz J 1975
Studies of the cloned 37-kDa subunit of activator 1 (replication factor C) of HeLa cells. Chen M, Pan ZQ, Hurwitz J 1992
Studies on the DNA elongation inhibitor and its proliferating cell nuclear antigen-dependent control in simian virus 40 DNA replication in vitro. Lee SH, Kwong AD, Ishimi Y, Hurwitz J 1989
Role of DNA polymerase alpha and DNA primase in simian virus 40 DNA replication in vitro. Murakami Y, Wobbe CR, Weissbach L, Dean FB, Hurwitz J 1986
DNA sequences required for the in vitro replication of adenovirus DNA. Guggenheimer RA, Stillman BW, Nagata K, Tamanoi F, Hurwitz J 1984
Disclosing the in vivo organization of a viral histone-like protein in Bacillus subtilis mediated by its capacity to recognize the viral genome. Holguera I, Ballesteros-Plaza D, Muñoz-Espín D, Salas M 2012
Properties of the human Cdc45/Mcm2-7/GINS helicase complex and its action with DNA polymerase {varepsilon} in rolling circle DNA synthesis. Kang YH, Galal WC, Farina A, Tappin I, Hurwitz J 2012
Y265C DNA polymerase beta knockin mice survive past birth and accumulate base excision repair intermediate substrates. Senejani AG, Dalal S, Liu Y, Nottoli TP, McGrath JM, Clairmont CS, Sweasy JB 2012
Structural basis of human DNA polymerase η-mediated chemoresistance to cisplatin. Zhao Y, Biertümpfel C, Gregory MT, Hua YJ, Hanaoka F, Yang WW 2012
Genomic footprinting in mammalian cells with ultraviolet light. Becker MM, Wang Z, Grossmann G, Becherer KA 1989
On the molecular basis of transition mutations: frequencies of forming 2-aminopurine.cytosine and adenine.cytosine base mispairs in vitro. Watanabe SM, Goodman MF 1981
Replication of simian virus 40 origin-containing DNA in vitro with purified proteins. Wobbe CR, Weissbach L, Borowiec JA, Dean FB, Murakami Y, Bullock P, Hurwitz J 1987
Mechanism of action of ribonuclease H isolated from avian myeloblastosis virus and Escherichia coli. Leis JP, Berkower I, Hurwitz J 1973
In situ analysis of repair processes for oxidative DNA damage in mammalian cells. Lan L, Nakajima S, Oohata Y, Takao M, Okano S, Masutani M, Wilson SH, Yasui A 2004
Different mutation signatures in DNA polymerase eta- and MSH6-deficient mice suggest separate roles in antibody diversification. Martomo SA, Yang WW, Wersto RP, Ohkumo T, Kondo Y, Yokoi M, Masutani C, Hanaoka F, Gearhart PJ 2005
Structure of the gene 2.5 protein, a single-stranded DNA binding protein encoded by bacteriophage T7. Hollis T, Stattel JM, Walther DS, Richardson CC, Ellenberger T 2001
An N-terminal fragment of the gene 4 helicase/primase of bacteriophage T7 retains primase activity in the absence of helicase activity. Frick DN, Baradaran K, Richardson CC 1998
A general two-metal-ion mechanism for catalytic RNA. Steitz TA, Steitz JA 1993
Viral terminal protein directs early organization of phage DNA replication at the bacterial nucleoid. Muñoz-Espín D, Holguera I, Ballesteros-Plaza D, Carballido-López R, Salas M 2010
Direct role for the RNA polymerase domain of T7 primase in primer delivery. Zhu B, Lee SJ, Richardson CC 2010
Residues in the central beta-hairpin of the DNA helicase of bacteriophage T7 are important in DNA unwinding. Satapathy AK, Kochaniak AB, Mukherjee S, Crampton DJ, van Oijen AM, Richardson CC 2010
Human DINB1-encoded DNA polymerase kappa is a promiscuous extender of mispaired primer termini. Washington MT, Johnson RE, Prakash L, Prakash S 2002
Genome-wide model for the normal eukaryotic DNA replication fork. Larrea AA, Lujan SA, Nick McElhinny SA, Mieczkowski PA, Resnick MA, Gordenin DA, Kunkel TA 2010
Frameshift errors initiated by nucleotide misincorporation. Bebenek K, Kunkel TA 1990
Infidelity of DNA synthesis associated with bypass of apurinic sites. Schaaper RM, Kunkel TA, Loeb LA 1983
Intrinsic apurinic/apyrimidinic (AP) endonuclease activity enables Bacillus subtilis DNA polymerase X to recognize, incise, and further repair abasic sites. Baños B, Villar L, Salas M, de Vega M 2010
Phage phi29 protein p56 prevents viral DNA replication impairment caused by uracil excision activity of uracil-DNA glycosylase. Serrano-Heras G, Bravo A, Salas M 2008
The vinyl chloride DNA derivative N2,3-ethenoguanine produces G----A transitions in Escherichia coli. Cheng KC, Preston BD, Cahill DS, Dosanjh MK, Singer B, Loeb LA 1991
Mutagenic potential of O4-methylthymine in vivo determined by an enzymatic approach to site-specific mutagenesis. Preston BD, Singer B, Loeb LA 1986
Depurination causes mutations in SOS-induced cells. Schaaper RM, Loeb LA 1981
Metal-induced infidelity during DNA synthesis. Sirover MA, Loeb LA 1976
Reverse transcriptase: correlation of zinc content with activity. Poiesz BJ, Seal G, Loeb LA 1974
Priming of DNA polymerase in nuclei of sea urchin embryos by native DNA. Loeb LA, Mazia D, Ruby AD 1967
Translesion DNA polymerases remodel the replisome and alter the speed of the replicative helicase. Indiani C, Langston LD, Yurieva O, Goodman MF, O'Donnell ME 2009
Roles of DNA polymerases V and II in SOS-induced error-prone and error-free repair in Escherichia coli. Pham P, Rangarajan S, Woodgate R, Goodman MF 2001
A fidelity assay using "dideoxy" DNA sequencing: a measurement of sequence dependence and frequency of forming 5-bromouracil X guanine base mispairs. Lasken RS, Goodman MF 1985
Evidence for an altered adenovirus DNA polymerase in cells infected with the mutant H5ts149. Friefeld BR, Lichy JH, Hurwitz J, Horwitz MS 1983
Hopping of a processivity factor on DNA revealed by single-molecule assays of diffusion. Komazin-Meredith G, Mirchev R, Golan DE, van Oijen AM, Coen DM 2008
Sequence and mapping analyses of the herpes simplex virus DNA polymerase gene predict a C-terminal substrate binding domain. Gibbs JS, Chiou HC, Hall JD, Mount DW, Retondo MJ, Weller SK, Coen DM 1985
Adenovirus DNA replication in vitro: identification of a host factor that stimulates synthesis of the preterminal protein-dCMP complex. Nagata K, Guggenheimer RA, Enomoto T, Lichy JH, Hurwitz J 1982
Adenovirus DNA replication in vitro: purification of the terminal protein in a functional form. Enomoto T, Lichy JH, Ikeda JE, Hurwitz J 1981
Elongation of primed DNA templates by eukaryotic DNA polymerases. Ikeda JE, Longiaru M, Horwitz MS, Hurwitz J 1980
The accessory subunit of mtDNA polymerase shares structural homology with aminoacyl-tRNA synthetases: implications for a dual role as a primer recognition factor and processivity clamp. Fan L, Sanschagrin PC, Kaguni LS, Kuhn LA 1999
Crystal structure of the GINS complex and functional insights into its role in DNA replication. Chang YP, Wang G, Bermudez V, Hurwitz J, Chen XS 2007
Studies on the interactions between human replication factor C and human proliferating cell nuclear antigen. Zhang G, Gibbs E, Kelman Z, O'Donnell ME, Hurwitz J 1999
Sequence and expression in Escherichia coli of the 40-kDa subunit of activator 1 (replication factor C) of HeLa cells. Chen M, Pan ZQ, Hurwitz J 1992
Molecular interactions in the priming complex of bacteriophage T7. Kulczyk AW, Richardson CC 2012
Involvement of escherichia coli dnaZ gene product in DNA elongation in vitro. Wickner S, Hurwitz J 1976
Initiation of replication in chromosomal DNA induced by extracts from proliferating cells. Jazwinski SM, Wang JL, Edelman GM 1976
Chromosomal location of the human gene for DNA polymerase beta. McBride OW, Zmudzka BZ, Wilson SH 1987
Structure of rat DNA polymerase beta revealed by partial amino acid sequencing and cDNA cloning. Zmudzka BZ, SenGupta D, Matsukage A, Cobianchi F, Kumar P, Wilson SH 1986
A human homolog of the Saccharomyces cerevisiae REV3 gene, which encodes the catalytic subunit of DNA polymerase zeta. Gibbs PE, McGregor WG, Maher VM, Nisson P, Lawrence CW 1998
Oncornavirus expression in human x mouse hybrid cells segregating mouse chromosomes. Minna JD, Gazdar AF, Iverson GM, Marshall TH, STORMBERG K, Wilson SH 1974
Mutator phenotypes of yeast strains heterozygous for mutations in the MSH2 gene. Drotschmann K, Clark AB, Tran HT, Resnick MA, Gordenin DA, Kunkel TA 1999
Unequal human immunodeficiency virus type 1 reverse transcriptase error rates with RNA and DNA templates. Boyer JC, Bebenek K, Kunkel TA 1992
Lethal mutagenesis of HIV with mutagenic nucleoside analogs. Loeb LA, Essigmann JM, Kazazi F, Zhang J, Rose KD, Mullins JI 1999
Posttranscriptional modification of retroviral primers is required for late stages of DNA replication. Burnett BP, McHenry CS 1997
Reverse transcriptase of human immunodeficiency virus can use either human tRNA(3Lys) or Escherichia coli tRNA(2Gln) as a primer in an in vitro primer-utilization assay. Kohlstaedt LA, Steitz TA 1992
Gene 1.7 of bacteriophage T7 confers sensitivity of phage growth to dideoxythymidine. Tran NQ, Rezende LF, Qimron U, Richardson CC, Tabor S 2008
Initiation of DNA replication at the primary origin of bacteriophage T7 by purified proteins: requirement for T7 RNA polymerase. Romano LJ, Tamanoi F, Richardson CC 1981
The gamma subunit of DNA polymerase III holoenzyme of Escherichia coli is produced by ribosomal frameshifting. Flower AM, McHenry CS 1990
UmuC mutagenesis protein of Escherichia coli: purification and interaction with UmuD and UmuD'. Woodgate R, Rajagopalan M, Lu C, Echols H 1989
Conversion of phiX174 and fd single-stranded DNA to replicative forms in extracts of Escherichia coli. Wickner RB, Wright M, Wickner S, Hurwitz J 1972
Two distinct loci confer resistance to acycloguanosine in herpes simplex virus type 1. Coen DM, Schaffer PA 1980
Conversion of phiX174 viral DNA to double-stranded form by purified Escherichia coli proteins. Wickner S, Hurwitz J 1974
Studies on the initiation of simian virus 40 replication in vitro: RNA primer synthesis and its elongation. Murakami Y, Eki T, Hurwitz J 1992
Studies on the initiation and elongation reactions in the simian virus 40 DNA replication system. Matsumoto T, Eki T, Hurwitz J 1990
Involvement of two protein factors and ATP in in vitro DNA synthesis catalyzed by DNA polymerase 3 of Escherichia coli. Hurwitz J, Wickner S 1974
ATP hydrolysis catalyzed by human replication factor C requires participation of multiple subunits. Cai J, Yao N, Gibbs E, Finkelstein J, Phillips B, O'Donnell ME, Hurwitz J 1998
In vitro reconstitution of human replication factor C from its five subunits. Uhlmann F, Cai J, Flores-Rozas H, Dean FB, Finkelstein J, O'Donnell ME, Hurwitz J 1996
The subunits of activator 1 (replication factor C) carry out multiple functions essential for proliferating-cell nuclear antigen-dependent DNA synthesis. Pan ZQ, Chen M, Hurwitz J 1993
Species-specific in vitro synthesis of DNA containing the polyoma virus origin of replication. Murakami Y, Eki T, Yamada M, Prives C, Hurwitz J 1986
Adenovirus DNA replication in vitro: synthesis of full-length DNA with purified proteins. Nagata K, Guggenheimer RA, Hurwitz J 1983
Adenoviral protein-primed initiation of DNA chains in vitro. Ikeda JE, Enomoto T, Hurwitz J 1982
Mechanism of ultraviolet-induced mutagenesis: extent and fidelity of in vitro DNA synthesis on irradiated templates. Villani G, Boiteux S, Radman M 1978
Knotted DNA from bacteriophage capsids. Liu LF, Perkocha L, Calendar R, Wang JC 1981
Reverse chemical mutagenesis: identification of the mutagenic lesions resulting from reactive oxygen species-mediated damage to DNA. Feig DI, Sowers LC, Loeb LA 1994
Structural basis of asymmetry in the human immunodeficiency virus type 1 reverse transcriptase heterodimer. Wang J, Smerdon SJ, Jäger J, Kohlstaedt LA, Rice PA, Friedman JM, Steitz TA 1994
Recognition by viral and cellular DNA polymerases of nucleosides bearing bases with nonstandard hydrogen bonding patterns. Horlacher J, Hottiger M, Podust VN, Hübscher U, Benner SA 1995
Active DNA unwinding dynamics during processive DNA replication. Morin JA, Cao FJ, Lázaro JM, Arias-Gonzalez JR, Valpuesta JM, Carrascosa JL, Salas M, Ibarra B 2012
The p15 carboxyl-terminal proteolysis product of the human immunodeficiency virus type 1 reverse transcriptase p66 has DNA polymerase activity. Hafkemeyer P, Ferrari E, Brecher J, Hübscher U 1991
The joining (J) chain is present in invertebrates that do not express immunoglobulins. Takahashi T, Iwase T, Takenouchi N, Saito M, Kobayashi K, Moldoveanu Z, Mestecky J, Moro I 1996
Suppressed catalytic activity of base excision repair enzymes on rotationally positioned uracil in nucleosomes. Beard BC, Wilson SH, Smerdon MJ 2003
A short adaptive path from DNA to RNA polymerases. Cozens C, Pinheiro VB, Vaisman A, Woodgate R, Holliger P 2012
Gene 5.5 protein of bacteriophage T7 in complex with Escherichia coli nucleoid protein H-NS and transfer RNA masks transfer RNA priming in T7 DNA replication. Zhu B, Lee SJ, Tan M, Wang ED, Richardson CC 2012
Pol31 and Pol32 subunits of yeast DNA polymerase δ are also essential subunits of DNA polymerase ζ Johnson RE, Prakash L, Prakash S 2012
2',5'-Bis-O-(tert-butyldimethylsilyl)-3'-spiro-5''-(4''-amino-1'',2''- oxathiole-2'',2'-dioxide)pyrimidine (TSAO) nucleoside analogues: highlyselective inhibitors of human immunodeficiency virus type 1 that are targeted at the viral reverse transcriptase. Balzarini J, Pérez-Pérez MJ, San-Félix A, Schols D, Perno CF, Vandamme AM, Camarasa MJ, De Clercq E 1992
Mechanism of inhibitory effect of dextran sulfate and heparin on replication of human immunodeficiency virus in vitro. Baba M, Pauwels R, Balzarini J, Arnout J, Desmyter J, De Clercq E 1988
Inhibition of oncornavirus functions by 2'-azido polynucleotides. De Clercq E, Billiau A, Hobbs J, Torrence PF, Witkop B 1975
Importance of compartment formation for a self-encoding system. Matsuura T, Yamaguchi M, Ko-Mitamura EP, Shima Y, Urabe I, Yomo T 2002
9-[(2RS)-3-fluoro-2-phosphonylmethoxypropyl] derivatives of purines: a class of highly selective antiretroviral agents in vitro and in vivo. Balzarini J, Holy A, Jindrich J, Dvorakova H, Hao Z, Snoeck R, Herdewijn P, Johns DG, De Clercq E 1991
Mutated K65R recombinant reverse transcriptase of human immunodeficiency virus type 1 shows diminished chain termination in the presence of 2',3'-dideoxycytidine 5'-triphosphate and other drugs. Gu Z, Arts EJ, Parniak MA, Wainberg MA 1995
On the mechanism of selective inhibition of herpesvirus replication by (E)-5-(2-bromovinyl)-2'-deoxyuridine. Allaudeen HS, Kozarich JW, Bertino JR, De Clercq E 1981
Potent and selective inhibition of human immunodeficiency virus type 1 (HIV-1) by 5-ethyl-6-phenylthiouracil derivatives through their interaction with the HIV-1 reverse transcriptase. Baba M, De Clercq E, Tanaka H, Ubasawa M, Takashima H, Sekiya K, Nitta I, Umezu K, Nakashima H, Mori S 1991
Mechanism of somatic hypermutation at the WA motif by human DNA polymerase η Zhao Y, Gregory MT, Biertümpfel C, Hua YJ, Hanaoka F, Yang WW 2013
Dual role for mammalian DNA polymerase ζ in maintaining genome stability and proliferative responses. Lange SS, Bedford E, Reh S, Wittschieben JP, Carbajal S, Kusewitt DF, DiGiovanni J, Wood RD 2013
RecA acts as a switch to regulate polymerase occupancy in a moving replication fork. Indiani C, Patel M, Goodman MF, O'Donnell ME 2013
Evidence for allosterism in in vitro DNA synthesis on RNA templates. Cavalieri LF, Modak MJ, Marcus SL 1974
Structure-function analysis of ribonucleotide bypass by B family DNA replicases. Clausen AR, Murray MS, Passer AR, Pedersen LC, Kunkel TA 2013
DNA polymerase δ-interacting protein 2 is a processivity factor for DNA polymerase λ during 8-oxo-7,8-dihydroguanine bypass. Maga G, Crespan E, Markkanen E, Imhof R, Furrer A, Villani G, Hübscher U, van Loon B 2013

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