HIV-specific cytotoxic T-lymphocyte activity in immunologically normal HIV-infected persons.

Bernard NF, Pederson K, Chung F, Ouellet L, Wainberg MA, Tsoukas CM
AIDS (London, England) (1998), Volume 12, Page 2125
PubMed entry

Abstract:

CD8+ T-cell counts usually increase soon after infection with HIV, ...
CD8+ T-cell counts usually increase soon after infection with HIV, whereas CD4+ cell counts decrease. The result of these changes in T-cell subpopulation subsets in most HIV-infected subjects is inversion of the CD4 : CD8 ratio from greater than 1.0 typical of uninfected persons to less than 1.0 after infection.

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